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Items: 1 to 50 of 71

1.

ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer.

Manshouri R, Coyaud E, Kundu ST, Peng DH, Stratton SA, Alton K, Bajaj R, Fradette JJ, Minelli R, Peoples MD, Carugo A, Chen F, Bristow C, Kovacs JJ, Barton MC, Heffernan T, Creighton CJ, Raught B, Gibbons DL.

Nat Commun. 2019 Nov 12;10(1):5125. doi: 10.1038/s41467-019-12832-z.

2.

Garden centre customer attitudes to pollinators and pollinator-friendly planting.

Wignall VR, Alton K, Ratnieks FLW.

PeerJ. 2019 Jun 7;7:e7088. doi: 10.7717/peerj.7088. eCollection 2019.

3.

Most ornamental plants on sale in garden centres are unattractive to flower-visiting insects.

Garbuzov M, Alton K, Ratnieks FL.

PeerJ. 2017 Mar 7;5:e3066. doi: 10.7717/peerj.3066. eCollection 2017.

4.

Defining Advanced Heart Failure: A Systematic Review of Criteria Used in Clinical Trials.

Bjork JB, Alton KK, Georgiopoulou VV, Butler J, Kalogeropoulos AP.

J Card Fail. 2016 Jul;22(7):569-77. doi: 10.1016/j.cardfail.2016.03.003. Epub 2016 Mar 11. Review.

PMID:
26975942
5.

Same-Day Discharge After Minimally Invasive Myomectomy.

Alton K, Sullivan S, Udaltsova N, Yamamoto M, Zaritsky E.

Obstet Gynecol. 2016 Mar;127(3):539-44. doi: 10.1097/AOG.0000000000001291.

PMID:
26855103
6.

Heart rate variability evaluation in the assessment and management of in-utero drug-exposed infants.

Nagiub M, Alton K, Avula V, Hagglund K, Anne P.

SAGE Open Med. 2014 Nov 6;2:2050312114556525. doi: 10.1177/2050312114556525. eCollection 2014.

7.

Infantile hypotonia with failure to thrive.

Nagiub M, Alton K, Anne P.

Am J Case Rep. 2012;13:214-7. doi: 10.12659/AJCR.883367. Epub 2012 Sep 5.

8.

Intestinal lymphatic transport for drug delivery.

Yáñez JA, Wang SW, Knemeyer IW, Wirth MA, Alton KB.

Adv Drug Deliv Rev. 2011 Sep 10;63(10-11):923-42. doi: 10.1016/j.addr.2011.05.019. Epub 2011 Jun 13. Review.

PMID:
21689702
9.

Metabolomics analysis reveals elevation of 3-indoxyl sulfate in plasma and brain during chemically-induced acute kidney injury in mice: investigation of nicotinic acid receptor agonists.

Zgoda-Pols JR, Chowdhury S, Wirth M, Milburn MV, Alexander DC, Alton KB.

Toxicol Appl Pharmacol. 2011 Aug 15;255(1):48-56. doi: 10.1016/j.taap.2011.05.015. Epub 2011 May 27.

PMID:
21640743
10.

Characterization of human liver enzymes involved in the biotransformation of boceprevir, a hepatitis C virus protease inhibitor.

Ghosal A, Yuan Y, Tong W, Su AD, Gu C, Chowdhury SK, Kishnani NS, Alton KB.

Drug Metab Dispos. 2011 Mar;39(3):510-21. doi: 10.1124/dmd.110.036996. Epub 2010 Dec 1.

PMID:
21123164
11.

Quantitation of parent drug and its unstable metabolites by in situ coulometric oxidation and liquid chromatography-tandem mass spectrometry.

Tong W, Chowdhury SK, Su AD, Alton KB.

Anal Chem. 2010 Dec 15;82(24):10251-7. doi: 10.1021/ac102538s. Epub 2010 Nov 24.

PMID:
21105697
12.

Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist.

Ghosal A, Lu X, Penner N, Gao L, Ramanathan R, Chowdhury SK, Kishnani NS, Alton KB.

Drug Metab Dispos. 2011 Jan;39(1):30-8. doi: 10.1124/dmd.110.035493. Epub 2010 Oct 6.

PMID:
20926621
13.

Identification of two novel metabolites of SCH 486757, a nociceptin/orphanin FQ peptide receptor agonist, in humans.

Penner NA, Ho G, Bercovici A, Chowdhury SK, Alton KB.

Drug Metab Dispos. 2010 Nov;38(11):2067-74. doi: 10.1124/dmd.110.032516. Epub 2010 Jul 29.

PMID:
20671096
14.

Metabolism of loratadine and further characterization of its in vitro metabolites.

Ghosal A, Gupta S, Ramanathan R, Yuan Y, Lu X, Su AD, Alvarez N, Zbaida S, Chowdhury SK, Alton KB.

Drug Metab Lett. 2009 Aug;3(3):162-70. Epub 2009 Aug 1.

PMID:
19702548
15.
16.
17.

Neurogenic potential of isolated precursor cells from early post-gastrula somitic tissue.

Tropepe V, Alton K, Sachewsky N, Cheng V, Kuo C, Morshead CM.

Stem Cells Dev. 2009 Dec;18(10):1533-42. doi: 10.1089/scd.2008.0359.

PMID:
19326969
18.

Identification of human liver cytochrome P450 enzymes involved in biotransformation of vicriviroc, a CCR5 receptor antagonist.

Ghosal A, Ramanathan R, Yuan Y, Hapangama N, Chowdhury SK, Kishnani NS, Alton KB.

Drug Metab Dispos. 2007 Dec;35(12):2186-95. Epub 2007 Sep 7.

PMID:
17827338
19.

Response normalized liquid chromatography nanospray ionization mass spectrometry.

Ramanathan R, Zhong R, Blumenkrantz N, Chowdhury SK, Alton KB.

J Am Soc Mass Spectrom. 2007 Oct;18(10):1891-9. Epub 2007 Jul 29.

20.

Disposition of desloratadine in healthy volunteers.

Ramanathan R, Reyderman L, Su AD, Alvarez N, Chowdhury SK, Alton KB, Wirth MA, Clement RP, Statkevich P, Patrick JE.

Xenobiotica. 2007 Jul;37(7):770-87.

PMID:
17620222
21.

Disposition of loratadine in healthy volunteers.

Ramanathan R, Reyderman L, Kulmatycki K, Su AD, Alvarez N, Chowdhury SK, Alton KB, Wirth MA, Clement RP, Statkevich P, Patrick JE.

Xenobiotica. 2007 Jul;37(7):753-69.

PMID:
17620221
22.

Metabolism-based identification of a potent thrombin receptor antagonist.

Clasby MC, Chackalamannil S, Czarniecki M, Doller D, Eagen K, Greenlee W, Kao G, Lin Y, Tsai H, Xia Y, Ahn HS, Agans-Fantuzzi J, Boykow G, Chintala M, Foster C, Smith-Torhan A, Alton K, Bryant M, Hsieh Y, Lau J, Palamanda J.

J Med Chem. 2007 Jan 11;50(1):129-38.

PMID:
17201416
24.

Application of mass spectrometry for metabolite identification.

Ma S, Chowdhury SK, Alton KB.

Curr Drug Metab. 2006 Jun;7(5):503-23. Review.

PMID:
16787159
25.

Metabolism and excretion of loratadine in male and female mice, rats and monkeys.

Ramanathan R, Alvarez N, Su AD, Chowdhury S, Alton K, Stauber K, Patrick J.

Xenobiotica. 2005 Feb;35(2):155-89.

PMID:
16019945
26.

Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 351125, a CCR5 antagonist.

Ghosal A, Chowdhury SK, Gupta S, Yuan Y, Iannucci R, Zhang H, Zbaida S, Patrick JE, Alton KB.

Xenobiotica. 2005 May;35(5):405-17.

PMID:
16012074
28.

Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions.

Kosoglou T, Statkevich P, Johnson-Levonas AO, Paolini JF, Bergman AJ, Alton KB.

Clin Pharmacokinet. 2005;44(5):467-94. Review.

PMID:
15871634
29.

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of 3-hydroxydesloratadine.

Ghosal A, Yuan Y, Hapangama N, Su AD, Alvarez N, Chowdhury SK, Alton KB, Patrick JE, Zbaida S.

Biopharm Drug Dispos. 2004 Sep;25(6):243-52.

PMID:
15334623
30.

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).

Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S.

Drug Metab Dispos. 2004 Mar;32(3):314-20.

PMID:
14977865
31.

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil).

Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S.

Drug Metab Dispos. 2004 Feb;32(2):267-71.

PMID:
14744950
32.

Assessment of temporal biochemical and gene transcription changes in rat liver cytochrome P450: utility of real-time quantitative RT-PCR.

Goodsaid FM, Palamanda JR, Montgomery D, Mandakas G, Gu C, Li Z, You X, Norton L, Smith R, Chu I, Soares T, Alton K, Kishnani NS, Rosenblum IY.

Pharm Res. 2003 Sep;20(9):1373-80.

PMID:
14567630
33.

First-trimester diagnosis of osteogenesis imperfecta type II by three-dimensional sonography.

McEwing RL, Alton K, Johnson J, Scioscia AL, Pretorius DH.

J Ultrasound Med. 2003 Mar;22(3):311-4. No abstract available.

PMID:
12636334
34.

High-performance liquid chromatographic method for the quantification of unbound evernimicin in human plasma ultrafiltrate.

Zhong R, Hernandez A, Alton KB, Kishnani NS, Patrick JE.

J Chromatogr B Analyt Technol Biomed Life Sci. 2002 May 25;772(1):191-5.

PMID:
12016032
35.

Disposition of the selective cholesterol absorption inhibitor ezetimibe in healthy male subjects.

Patrick JE, Kosoglou T, Stauber KL, Alton KB, Maxwell SE, Zhu Y, Statkevich P, Iannucci R, Chowdhury S, Affrime M, Cayen MN.

Drug Metab Dispos. 2002 Apr;30(4):430-7.

PMID:
11901097
36.

Fragmentation of N-oxides (deoxygenation) in atmospheric pressure ionization: investigation of the activation process.

Tong W, Chowdhury SK, Chen JC, Zhong R, Alton KB, Patrick JE.

Rapid Commun Mass Spectrom. 2001;15(22):2085-90.

PMID:
11746872
38.

Bioavailability and metabolism of mometasone furoate following administration by metered-dose and dry-powder inhalers in healthy human volunteers.

Affrime MB, Cuss F, Padhi D, Wirth M, Pai S, Clement RP, Lim J, Kantesaria B, Alton K, Cayen MN.

J Clin Pharmacol. 2000 Nov;40(11):1227-36.

PMID:
11075308
39.

Combined chemotherapy of murine mammary tumors by local activation of the prodrugs ifosfamide and 5-fluorocytosine.

Kammertoens T, Gelbmann W, Karle P, Alton K, Saller R, Salmons B, Günzburg WH, Uckert W.

Cancer Gene Ther. 2000 Apr;7(4):629-36.

40.

Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663.

van Heek M, Farley C, Compton DS, Hoos L, Alton KB, Sybertz EJ, Davis HR Jr.

Br J Pharmacol. 2000 Apr;129(8):1748-54.

41.

Liquid chromatography/mass spectrometry methods for distinguishing N-oxides from hydroxylated compounds

Ramanathan R, Su AD, Alvarez N, Blumenkrantz N, Chowdhury SK, Alton K, Patrick J.

Anal Chem. 2000 Mar 15;72(6):1352-9.

PMID:
10740882
42.
43.

Presence of p53 mutations in feline neoplasms.

Mayr B, Blauensteiner J, Edlinger A, Reifinger M, Alton K, Schaffner G, Brem G.

Res Vet Sci. 2000 Feb;68(1):63-70.

PMID:
10684760
44.

Novel canine tumour suppressor gene p53 mutations in cases of skin and mammary neoplasms.

Mayr B, Reifinger M, Alton K.

Vet Res Commun. 1999 Aug;23(5):285-91.

PMID:
10493115
45.

Magnetic resonance imaging and ultrasonography of the lumbricale muscles in the horse.

Bindeus T, Rand T, Alton K, Imhof H, Stanek C.

Aust Vet J. 1999 Feb;77(2):82-4. No abstract available.

PMID:
10078352
46.

Absorption, metabolism, and excretion of 14C-temozolomide following oral administration to patients with advanced cancer.

Baker SD, Wirth M, Statkevich P, Reidenberg P, Alton K, Sartorius SE, Dugan M, Cutler D, Batra V, Grochow LB, Donehower RC, Rowinsky EK.

Clin Cancer Res. 1999 Feb;5(2):309-17.

47.

Low-field magnetic resonance imaging (0.2 T) of tendons with sonographic and histologic correlation. Cadaveric study.

Rand T, Bindeus T, Alton K, Voegele T, Kukla C, Stanek C, Imhof H.

Invest Radiol. 1998 Aug;33(8):433-8.

PMID:
9704281
48.

Novel p53 tumour suppressor mutations in cases of spindle cell sarcoma, pleomorphic sarcoma and fibrosarcoma in cats.

Mayr B, Reifinger M, Alton K, Schaffner G.

Vet Res Commun. 1998 Jun;22(4):249-55.

PMID:
9686439
49.

[Radiologically detectable changes in the radial annular ligament and the supinator muscle of the domestic cat (Felis catus)].

Breit S, Künzel W, Alton K, Kneissl S, Mayrhofer E.

Schweiz Arch Tierheilkd. 1998;140(6):231-9. German.

PMID:
9646712
50.

Disposition of 14C-eptifibatide after intravenous administration to healthy men.

Alton KB, Kosoglou T, Baker S, Affrime MB, Cayen MN, Patrick JE.

Clin Ther. 1998 Mar-Apr;20(2):307-23.

PMID:
9589822

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