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Items: 1 to 50 of 67

1.

The iron-sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation.

Simon AK, Kummer S, Wild S, Lezaja A, Teloni F, Jozwiakowski SK, Altmeyer M, Gari K.

Life Sci Alliance. 2020 Feb 18;3(3). pii: e201900547. doi: 10.26508/lsa.201900547. Print 2020 Mar.

2.

Basal CHK1 activity safeguards its stability to maintain intrinsic S-phase checkpoint functions.

Michelena J, Gatti M, Teloni F, Imhof R, Altmeyer M.

J Cell Biol. 2019 Sep 2;218(9):2865-2875. doi: 10.1083/jcb.201902085. Epub 2019 Jul 31.

PMID:
31366665
3.

Phase separation of 53BP1 determines liquid-like behavior of DNA repair compartments.

Kilic S, Lezaja A, Gatti M, Bianco E, Michelena J, Imhof R, Altmeyer M.

EMBO J. 2019 Aug 15;38(16):e101379. doi: 10.15252/embj.2018101379. Epub 2019 Jul 1.

4.

Efficient Pre-mRNA Cleavage Prevents Replication-Stress-Associated Genome Instability.

Teloni F, Michelena J, Lezaja A, Kilic S, Ambrosi C, Menon S, Dobrovolna J, Imhof R, Janscak P, Baubec T, Altmeyer M.

Mol Cell. 2019 Feb 21;73(4):670-683.e12. doi: 10.1016/j.molcel.2018.11.036. Epub 2019 Jan 10.

5.

Cells take a break when they are TIARed.

Altmeyer M.

EMBO Rep. 2019 Jan;20(1). pii: e47403. doi: 10.15252/embr.201847403. Epub 2018 Dec 11. No abstract available.

6.

Chromatin modifiers Mdm2 and RNF2 prevent RNA:DNA hybrids that impair DNA replication.

Klusmann I, Wohlberedt K, Magerhans A, Teloni F, Korbel JO, Altmeyer M, Dobbelstein M.

Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11311-E11320. doi: 10.1073/pnas.1809592115. Epub 2018 Nov 9.

7.

CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress.

Przetocka S, Porro A, Bolck HA, Walker C, Lezaja A, Trenner A, von Aesch C, Himmels SF, D'Andrea AD, Ceccaldi R, Altmeyer M, Sartori AA.

Mol Cell. 2018 Nov 1;72(3):568-582.e6. doi: 10.1016/j.molcel.2018.09.014. Epub 2018 Oct 18.

8.

Effects of locally applied adipose tissue-derived microvascular fragments by thermoresponsive hydrogel on bone healing.

Orth M, Altmeyer MAB, Scheuer C, Braun BJ, Holstein JH, Eglin D, D'Este M, Histing T, Laschke MW, Pohlemann T, Menger MD.

Acta Biomater. 2018 Sep 1;77:201-211. doi: 10.1016/j.actbio.2018.07.029. Epub 2018 Jul 17.

PMID:
30030175
9.

Analysis of PARP inhibitor toxicity by multidimensional fluorescence microscopy reveals mechanisms of sensitivity and resistance.

Michelena J, Lezaja A, Teloni F, Schmid T, Imhof R, Altmeyer M.

Nat Commun. 2018 Jul 11;9(1):2678. doi: 10.1038/s41467-018-05031-9.

10.

Publisher Correction: Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability.

Bosshard M, Aprigliano R, Gattiker C, Palibrk V, Markkanen E, Backe PH, Pellegrino S, Raymond FL, Froyen G, Altmeyer M, Bjørås M, Dianov GL, Loon BV.

Sci Rep. 2018 Apr 12;8(1):6010. doi: 10.1038/s41598-018-24189-2.

11.

The memory remains.

Altmeyer M.

Aging (Albany NY). 2018 Mar 29;10(4):516-517. doi: 10.18632/aging.101408. No abstract available.

12.

Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability.

Bosshard M, Aprigliano R, Gattiker C, Palibrk V, Markkanen E, Backe PH, Pellegrino S, Raymond FL, Froyen G, Altmeyer M, Bjørås M, Dianov GL, van Loon B.

Sci Rep. 2017 Nov 8;7(1):15050. doi: 10.1038/s41598-017-15380-y. Erratum in: Sci Rep. 2018 Apr 12;8(1):6010.

13.

Inherited DNA lesions determine G1 duration in the next cell cycle.

Lezaja A, Altmeyer M.

Cell Cycle. 2018;17(1):24-32. doi: 10.1080/15384101.2017.1383578. Epub 2017 Nov 9.

14.

Primary T cells for mRNA-mediated immunotoxin delivery.

Eggers R, Philippi A, Altmeyer MO, Breinig F, Schmitt MJ.

Gene Ther. 2018 Jan;25(1):47-53. doi: 10.1038/gt.2017.87. Epub 2017 Sep 22.

PMID:
28937681
15.

Cell Cycle Resolved Measurements of Poly(ADP-Ribose) Formation and DNA Damage Signaling by Quantitative Image-Based Cytometry.

Michelena J, Altmeyer M.

Methods Mol Biol. 2017;1608:57-68. doi: 10.1007/978-1-4939-6993-7_5.

PMID:
28695503
16.

Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin.

Pellegrino S, Michelena J, Teloni F, Imhof R, Altmeyer M.

Cell Rep. 2017 May 30;19(9):1819-1831. doi: 10.1016/j.celrep.2017.05.016.

17.

A Mechanism for Controlled Breakage of Under-replicated Chromosomes during Mitosis.

Duda H, Arter M, Gloggnitzer J, Teloni F, Wild P, Blanco MG, Altmeyer M, Matos J.

Dev Cell. 2017 Feb 27;40(4):421-422. doi: 10.1016/j.devcel.2017.02.015. No abstract available.

18.

A Mechanism for Controlled Breakage of Under-replicated Chromosomes during Mitosis.

Duda H, Arter M, Gloggnitzer J, Teloni F, Wild P, Blanco MG, Altmeyer M, Matos J.

Dev Cell. 2016 Dec 19;39(6):740-755. doi: 10.1016/j.devcel.2016.11.017. Erratum in: Dev Cell. 2017 Feb 27;40(4):421-422.

19.

53BP1 fosters fidelity of homology-directed DNA repair.

Ochs F, Somyajit K, Altmeyer M, Rask MB, Lukas J, Lukas C.

Nat Struct Mol Biol. 2016 Aug;23(8):714-21. doi: 10.1038/nsmb.3251. Epub 2016 Jun 27.

PMID:
27348077
20.

Evidence for Eight-Node Mixed-Symmetry Superconductivity in a Correlated Organic Metal.

Guterding D, Diehl S, Altmeyer M, Methfessel T, Tutsch U, Schubert H, Lang M, Müller J, Huth M, Jeschke HO, Valentí R, Jourdan M, Elmers HJ.

Phys Rev Lett. 2016 Jun 10;116(23):237001. doi: 10.1103/PhysRevLett.116.237001. Epub 2016 Jun 7.

PMID:
27341250
21.

PKCα and HMGB1 antagonistically control hydrogen peroxide-induced poly-ADP-ribose formation.

Andersson A, Bluwstein A, Kumar N, Teloni F, Traenkle J, Baudis M, Altmeyer M, Hottiger MO.

Nucleic Acids Res. 2016 Sep 19;44(16):7630-45. doi: 10.1093/nar/gkw442. Epub 2016 May 19.

22.

Interplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic Stress.

Pellegrino S, Altmeyer M.

Front Genet. 2016 Apr 19;7:63. doi: 10.3389/fgene.2016.00063. eCollection 2016. Review.

23.

Magnetism, Spin Texture, and In-Gap States: Atomic Specialization at the Surface of Oxygen-Deficient SrTiO_{3}.

Altmeyer M, Jeschke HO, Hijano-Cubelos O, Martins C, Lechermann F, Koepernik K, Santander-Syro AF, Rozenberg MJ, Valentí R, Gabay M.

Phys Rev Lett. 2016 Apr 15;116(15):157203. doi: 10.1103/PhysRevLett.116.157203. Epub 2016 Apr 14.

PMID:
27127984
24.

Phase Separation: Linking Cellular Compartmentalization to Disease.

Aguzzi A, Altmeyer M.

Trends Cell Biol. 2016 Jul;26(7):547-558. doi: 10.1016/j.tcb.2016.03.004. Epub 2016 Apr 1. Review.

PMID:
27051975
25.

A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells.

Ahuja AK, Jodkowska K, Teloni F, Bizard AH, Zellweger R, Herrador R, Ortega S, Hickson ID, Altmeyer M, Mendez J, Lopes M.

Nat Commun. 2016 Feb 15;7:10660. doi: 10.1038/ncomms10660.

26.

Readers of poly(ADP-ribose): designed to be fit for purpose.

Teloni F, Altmeyer M.

Nucleic Acids Res. 2016 Feb 18;44(3):993-1006. doi: 10.1093/nar/gkv1383. Epub 2015 Dec 15. Review.

27.

Models for the Detection of Deviations from the Expected Processing Strategy in Completing the Items of Cognitive Measures.

Schweizer K, Altmeyer M, Ren X, Schreiner M.

Multivariate Behav Res. 2015;50(5):544-54. doi: 10.1080/00273171.2015.1032397. Epub 2015 Aug 5.

PMID:
26610252
28.

A lncRNA to repair DNA.

Lukas J, Altmeyer M.

EMBO Rep. 2015 Nov;16(11):1413-4. doi: 10.15252/embr.201541309. Epub 2015 Sep 29.

29.

Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose).

Altmeyer M, Neelsen KJ, Teloni F, Pozdnyakova I, Pellegrino S, Grøfte M, Rask MD, Streicher W, Jungmichel S, Nielsen ML, Lukas J.

Nat Commun. 2015 Aug 19;6:8088. doi: 10.1038/ncomms9088.

30.

Microfluidic Superheating for Peptide Sequence Elucidation.

Altmeyer MO, Manz A, Neužil P.

Anal Chem. 2015 Jun 16;87(12):5997-6003. doi: 10.1021/acs.analchem.5b00189. Epub 2015 Jun 2.

PMID:
26035024
31.

Beta-aminoketones as prodrugs for selective irreversible inhibitors of type-1 methionine aminopeptidases.

Altmeyer M, Amtmann E, Heyl C, Marschner A, Scheidig AJ, Klein CD.

Bioorg Med Chem Lett. 2014 Nov 15;24(22):5310-4. doi: 10.1016/j.bmcl.2014.09.047. Epub 2014 Sep 23.

PMID:
25293447
32.

The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage.

Larsen DH, Hari F, Clapperton JA, Gwerder M, Gutsche K, Altmeyer M, Jungmichel S, Toledo LI, Fink D, Rask MB, Grøfte M, Lukas C, Nielsen ML, Smerdon SJ, Lukas J, Stucki M.

Nat Cell Biol. 2014 Aug;16(8):792-803. doi: 10.1038/ncb3007. Epub 2014 Jul 27.

33.

ATR prohibits replication catastrophe by preventing global exhaustion of RPA.

Toledo LI, Altmeyer M, Rask MB, Lukas C, Larsen DH, Povlsen LK, Bekker-Jensen S, Mailand N, Bartek J, Lukas J.

Cell. 2013 Nov 21;155(5):1088-103. doi: 10.1016/j.cell.2013.10.043. Erratum in: Cell. 2014 Jan 16;156(1-2):374.

34.

Proteome-wide identification of poly(ADP-Ribosyl)ation targets in different genotoxic stress responses.

Jungmichel S, Rosenthal F, Altmeyer M, Lukas J, Hottiger MO, Nielsen ML.

Mol Cell. 2013 Oct 24;52(2):272-85. doi: 10.1016/j.molcel.2013.08.026. Epub 2013 Sep 19.

35.

The chromatin scaffold protein SAFB1 renders chromatin permissive for DNA damage signaling.

Altmeyer M, Toledo L, Gudjonsson T, Grøfte M, Rask MB, Lukas C, Akimov V, Blagoev B, Bartek J, Lukas J.

Mol Cell. 2013 Oct 24;52(2):206-20. doi: 10.1016/j.molcel.2013.08.025. Epub 2013 Sep 19.

36.

Guarding against collateral damage during chromatin transactions.

Altmeyer M, Lukas J.

Cell. 2013 Jun 20;153(7):1431-4. doi: 10.1016/j.cell.2013.05.044. Review.

37.

Fast spore breaking by superheating.

Přibylka A, Almeida AV, Altmeyer MO, Petr J, Sevčík J, Manz A, Neužil P.

Lab Chip. 2013 May 7;13(9):1695-8. doi: 10.1039/c3lc41305e.

PMID:
23474861
38.

Process-based account for the effects of perceptual attention and executive attention on fluid intelligence: an integrative approach.

Ren X, Altmeyer M, Reiss S, Schweizer K.

Acta Psychol (Amst). 2013 Feb;142(2):195-202. doi: 10.1016/j.actpsy.2012.12.007. Epub 2013 Jan 19.

PMID:
23337082
39.

To spread or not to spread--chromatin modifications in response to DNA damage.

Altmeyer M, Lukas J.

Curr Opin Genet Dev. 2013 Apr;23(2):156-65. doi: 10.1016/j.gde.2012.11.001. Epub 2013 Jan 9. Review.

PMID:
23312207
40.

Addicted to PAR? A closer look at PARP inhibitor sensitivity.

Altmeyer M.

Cell Cycle. 2012 Nov 1;11(21):3916. doi: 10.4161/cc.22393. Epub 2012 Oct 3. No abstract available.

41.

TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes.

Gudjonsson T, Altmeyer M, Savic V, Toledo L, Dinant C, Grøfte M, Bartkova J, Poulsen M, Oka Y, Bekker-Jensen S, Mailand N, Neumann B, Heriche JK, Shearer R, Saunders D, Bartek J, Lukas J, Lukas C.

Cell. 2012 Aug 17;150(4):697-709. doi: 10.1016/j.cell.2012.06.039. Epub 2012 Aug 9. Erratum in: Cell. 2014 Dec 4;159(6):1476-7.

42.

Molecular cloning, structure, and reactivity of the second bromoperoxidase from Ascophyllum nodosum.

Wischang D, Radlow M, Schulz H, Vilter H, Viehweger L, Altmeyer MO, Kegler C, Herrmann J, Müller R, Gaillard F, Delage L, Leblanc C, Hartung J.

Bioorg Chem. 2012 Oct;44:25-34. doi: 10.1016/j.bioorg.2012.05.003. Epub 2012 Jun 23.

PMID:
22884431
43.

Cutaneous mercury granuloma: a case report.

Altmeyer MD, Burgdorf MR, Newsome RE, Wang AR.

Cutis. 2011 Oct;88(4):189-93.

PMID:
22106728
44.

Sandpaper dermatitis on a 17-month-old girl. Bacterial infectious panniculitis.

Black JM, Le L, Altmeyer M, Luster W, Shrum J, Wang A.

Arch Dermatol. 2011 Apr;147(4):499-504. doi: 10.1001/archdermatol.2011.62-a. No abstract available.

PMID:
21482905
45.

Therapeutic hotline. Abatacept: our experience of use in two patients with refractory psoriasis and psoriatic arthritis.

Altmeyer MD, Kerisit KG, Boh EE.

Dermatol Ther. 2011 Mar-Apr;24(2):287-90. doi: 10.1111/j.1529-8019.2011.01405.x.

PMID:
21410619
46.

Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding.

Asher G, Reinke H, Altmeyer M, Gutierrez-Arcelus M, Hottiger MO, Schibler U.

Cell. 2010 Sep 17;142(6):943-53. doi: 10.1016/j.cell.2010.08.016. Epub 2010 Sep 9.

47.

Inhibition of ADP ribosylation prevents and cures helicobacter-induced gastric preneoplasia.

Toller IM, Altmeyer M, Kohler E, Hottiger MO, Müller A.

Cancer Res. 2010 Jul 15;70(14):5912-22. doi: 10.1158/0008-5472.CAN-10-0528.

48.

Subtype-selectivity of metal-dependent methionine aminopeptidase inhibitors.

Altmeyer MA, Marschner A, Schiffmann R, Klein CD.

Bioorg Med Chem Lett. 2010 Jul 15;20(14):4038-44. doi: 10.1016/j.bmcl.2010.05.093. Epub 2010 May 27.

PMID:
20621724
49.

PARP1 ADP-ribosylates lysine residues of the core histone tails.

Messner S, Altmeyer M, Zhao H, Pozivil A, Roschitzki B, Gehrig P, Rutishauser D, Huang D, Caflisch A, Hottiger MO.

Nucleic Acids Res. 2010 Oct;38(19):6350-62. doi: 10.1093/nar/gkq463. Epub 2010 Jun 4.

50.

Absence of poly(ADP-ribose) polymerase 1 delays the onset of Salmonella enterica serovar Typhimurium-induced gut inflammation.

Altmeyer M, Barthel M, Eberhard M, Rehrauer H, Hardt WD, Hottiger MO.

Infect Immun. 2010 Aug;78(8):3420-31. doi: 10.1128/IAI.00211-10. Epub 2010 Jun 1.

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