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Items: 1 to 50 of 139

1.

Muco-Obstructive Lung Diseases.

Boyton RJ, Altmann DM.

N Engl J Med. 2019 Sep 5;381(10):e20. doi: 10.1056/NEJMc1907962. No abstract available.

PMID:
31483985
2.

Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C.

Sim MJW, Rajagopalan S, Altmann DM, Boyton RJ, Sun PD, Long EO.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12964-12973. doi: 10.1073/pnas.1903781116. Epub 2019 May 28.

3.

Knowns and unknowns of tissue-resident memory T cells.

Altmann DM.

Immunology. 2019 May;157(1):1-2. doi: 10.1111/imm.13062.

PMID:
30977128
4.

Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial.

Chambers ES, Byrne CS, Morrison DJ, Murphy KG, Preston T, Tedford C, Garcia-Perez I, Fountana S, Serrano-Contreras JI, Holmes E, Reynolds CJ, Roberts JF, Boyton RJ, Altmann DM, McDonald JAK, Marchesi JR, Akbar AN, Riddell NE, Wallis GA, Frost GS.

Gut. 2019 Aug;68(8):1430-1438. doi: 10.1136/gutjnl-2019-318424. Epub 2019 Apr 10.

5.

'Just 17 if you know what I mean' … but what do we really mean to say about Th17 immunity?

Altmann DM.

Immunology. 2019 Apr;156(4):297-298. doi: 10.1111/imm.13055.

PMID:
30873603
6.

Bioluminescent Reporting of In Vivo IFN-γ Immune Responses during Infection and Autoimmunity.

Reynolds CJ, Chong DLW, Li Y, Black SL, Cutler A, Webster Z, Manji J, Altmann DM, Boyton RJ.

J Immunol. 2019 Apr 15;202(8):2502-2510. doi: 10.4049/jimmunol.1801453. Epub 2019 Feb 27.

7.

The immune regulatory role of neutrophils.

Altmann DM.

Immunology. 2019 Mar;156(3):215-216. doi: 10.1111/imm.13049.

PMID:
30767207
8.

Natural killer cell transcriptional control, subsets, receptors and effector function.

Altmann DM.

Immunology. 2019 Feb;156(2):109-110. doi: 10.1111/imm.13041.

PMID:
30632618
9.

T-cell immunology of the lung: maintaining the balance between host defence and immune pathology.

Altmann DM.

Immunology. 2019 Jan;156(1):1-2. doi: 10.1111/imm.13029.

PMID:
30522167
10.

Functions of adipose-resident immune subsets and the impact on metabolic syndrome.

Altmann DM.

Immunology. 2018 Dec;155(4):405-406. doi: 10.1111/imm.13015.

PMID:
30417378
11.

A Nobel Prize-worthy pursuit: cancer immunology and harnessing immunity to tumour neoantigens.

Altmann DM.

Immunology. 2018 Nov;155(3):283-284. doi: 10.1111/imm.13008.

PMID:
30320408
12.

Regulatory T-cells: receptors, repertoires and roles in disease.

Altmann DM.

Immunology. 2018 Oct;155(2):153-154. doi: 10.1111/imm.12999.

13.

Bioinformatics for immunologists.

Altmann DM.

Immunology. 2018 Sep;155(1):1-2. doi: 10.1111/imm.12987.

14.
15.

Lung Defense through IL-8 Carries a Cost of Chronic Lung Remodeling and Impaired Function.

Reynolds CJ, Quigley K, Cheng X, Suresh A, Tahir S, Ahmed-Jushuf F, Nawab K, Choy K, Walker SA, Mathie SA, Sim M, Stowell J, Manji J, Pollard T, Altmann DM, Boyton RJ.

Am J Respir Cell Mol Biol. 2018 Nov;59(5):557-571. doi: 10.1165/rcmb.2018-0007OC.

16.

Neuroimmunology and neuroinflammation in autoimmune, neurodegenerative and psychiatric disease.

Altmann DM.

Immunology. 2018 Jun;154(2):167-168. doi: 10.1111/imm.12943.

17.

Mapping innate and adaptive immune function in arbovirus infections.

Altmann DM.

Immunology. 2018 May;154(1):1-2. doi: 10.1111/imm.12932. No abstract available.

18.

Immune Control of Burkholderia pseudomallei--Common, High-Frequency T-Cell Responses to a Broad Repertoire of Immunoprevalent Epitopes.

Nithichanon A, Rinchai D, Buddhisa S, Saenmuang P, Kewcharoenwong C, Kessler B, Khaenam P, Chetchotisakd P, Maillere B, Robinson J, Reynolds CJ, Boyton RJ, Altmann DM, Lertmemongkolchai G.

Front Immunol. 2018 Mar 20;9:484. doi: 10.3389/fimmu.2018.00484. eCollection 2018.

19.

T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses.

Reynolds CJ, Suleyman OM, Ortega-Prieto AM, Skelton JK, Bonnesoeur P, Blohm A, Carregaro V, Silva JS, James EA, Maillère B, Dorner M, Boyton RJ, Altmann DM.

Sci Rep. 2018 Jan 12;8(1):672. doi: 10.1038/s41598-017-18781-1.

20.

Infection with Burkholderia pseudomallei - immune correlates of survival in acute melioidosis.

Dunachie SJ, Jenjaroen K, Reynolds CJ, Quigley KJ, Sergeant R, Sumonwiriya M, Chaichana P, Chumseng S, Ariyaprasert P, Lassaux P, Gourlay L, Promwong C, Teparrukkul P, Limmathurotsakul D, Day NPJ, Altmann DM, Boyton RJ.

Sci Rep. 2017 Sep 22;7(1):12143. doi: 10.1038/s41598-017-12331-5.

21.

Guillain-Barré syndrome and arboviral infection in Brazil.

Keesen TSL, de Almeida RP, Gois BM, Peixoto RF, Pachá ASC, Vieira FCF, Paixão M, Cazzaniga R, Boyton RJ, Altmann DM.

Lancet Infect Dis. 2017 Jul;17(7):693-694. doi: 10.1016/S1473-3099(17)30333-X. Epub 2017 Jun 21. No abstract available.

22.

Canonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-C Allotypes Is Dictated by Peptides Bound to HLA-C.

Sim MJ, Malaker SA, Khan A, Stowell JM, Shabanowitz J, Peterson ME, Rajagopalan S, Hunt DF, Altmann DM, Long EO, Boyton RJ.

Front Immunol. 2017 Mar 14;8:193. doi: 10.3389/fimmu.2017.00193. eCollection 2017.

23.

Bronchiectasis: Current Concepts in Pathogenesis, Immunology, and Microbiology.

Boyton RJ, Altmann DM.

Annu Rev Pathol. 2016 May 23;11:523-54. doi: 10.1146/annurev-pathol-012615-044344. Epub 2016 Mar 2. Review.

PMID:
26980162
24.

BIITE: A Tool to Determine HLA Class II Epitopes from T Cell ELISpot Data.

Boelen L, O'Neill PK, Quigley KJ, Reynolds CJ, Maillere B, Robinson JH, Lertmemongkolchai G, Altmann DM, Boyton RJ, Asquith B.

PLoS Comput Biol. 2016 Mar 8;12(3):e1004796. doi: 10.1371/journal.pcbi.1004796. eCollection 2016 Mar.

25.

CD4+ T Cells Targeting Dominant and Cryptic Epitopes from Bacillus anthracis Lethal Factor.

Ascough S, Ingram RJ, Chu KK, Musson JA, Moore SJ, Gallagher T, Baillie L, Williamson ED, Robinson JH, Maillere B, Boyton RJ, Altmann DM.

Front Microbiol. 2016 Jan 5;6:1506. doi: 10.3389/fmicb.2015.01506. eCollection 2015.

26.

KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells.

Sim MJ, Stowell J, Sergeant R, Altmann DM, Long EO, Boyton RJ.

Eur J Immunol. 2016 Jan;46(1):185-91. doi: 10.1002/eji.201545757. Epub 2015 Nov 2.

27.

Whole genome protein microarrays for serum profiling of immunodominant antigens of Bacillus anthracis.

Kempsell KE, Kidd SP, Lewandowski K, Elmore MJ, Charlton S, Yeates A, Cuthbertson H, Hallis B, Altmann DM, Rogers M, Wattiau P, Ingram RJ, Brooks T, Vipond R.

Front Microbiol. 2015 Aug 13;6:747. doi: 10.3389/fmicb.2015.00747. eCollection 2015.

28.

Natural cutaneous anthrax infection, but not vaccination, induces a CD4(+) T cell response involving diverse cytokines.

Ingram RJ, Ascough S, Reynolds CJ, Metan G, Doganay M, Baillie L, Williamson DE, Robinson JH, Maillere B, Boyton RJ, Altmann DM.

Cell Biosci. 2015 Apr 26;5:20. doi: 10.1186/s13578-015-0011-4. eCollection 2015.

29.

Design, recruitment, and microbiological considerations in human challenge studies.

Darton TC, Blohmke CJ, Moorthy VS, Altmann DM, Hayden FG, Clutterbuck EA, Levine MM, Hill AV, Pollard AJ.

Lancet Infect Dis. 2015 Jul;15(7):840-51. doi: 10.1016/S1473-3099(15)00068-7. Epub 2015 May 27. Review.

PMID:
26026195
30.

Consensus on the development of vaccines against naturally acquired melioidosis.

Limmathurotsakul D, Funnell SG, Torres AG, Morici LA, Brett PJ, Dunachie S, Atkins T, Altmann DM, Bancroft G, Peacock SJ; Steering Group on Melioidosis Vaccine Development.

Emerg Infect Dis. 2015 Jun;21(6). doi: 10.3201/eid2106.141480.

31.

Autoantigen cross-reactive environmental antigen can trigger multiple sclerosis-like disease.

Reynolds CJ, Sim MJ, Quigley KJ, Altmann DM, Boyton RJ.

J Neuroinflammation. 2015 May 13;12:91. doi: 10.1186/s12974-015-0313-9.

32.

MS in South Asians in England: early disease onset and novel pattern of myelin autoimmunity.

Nicholas RS, Kostadima V, Hanspal M, Wakerley BR, Sergeant R, Decuypere S, Malik O, Boyton RJ, Altmann DM.

BMC Neurol. 2015 May 3;15:72. doi: 10.1186/s12883-015-0324-2.

33.

Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of "Humanized" Multiple Sclerosis-like Disease.

Kaushansky N, Eisenstein M, Boura-Halfon S, Hansen BE, Nielsen CH, Milo R, Zeilig G, Lassmann H, Altmann DM, Ben-Nun A.

J Biol Chem. 2015 Jun 12;290(24):15260-78. doi: 10.1074/jbc.M115.641209. Epub 2015 Apr 24.

34.

Anthrax in injecting drug users: the need for increased vigilance in the clinic.

Ascough S, Altmann DM.

Expert Rev Anti Infect Ther. 2015 Jun;13(6):681-4. doi: 10.1586/14787210.2015.1032255. Epub 2015 Apr 1.

PMID:
25831413
35.

Chronic Infection by Mucoid Pseudomonas aeruginosa Associated with Dysregulation in T-Cell Immunity to Outer Membrane Porin F.

Quigley KJ, Reynolds CJ, Goudet A, Raynsford EJ, Sergeant R, Quigley A, Worgall S, Bilton D, Wilson R, Loebinger MR, Maillere B, Altmann DM, Boyton RJ.

Am J Respir Crit Care Med. 2015 Jun 1;191(11):1250-64. doi: 10.1164/rccm.201411-1995OC.

36.

Host immunity to Bacillus anthracis lethal factor and other immunogens: implications for vaccine design.

Altmann DM.

Expert Rev Vaccines. 2015 Mar;14(3):429-34. doi: 10.1586/14760584.2015.981533. Epub 2014 Nov 17. Review.

PMID:
25400140
37.

CD4+ T cell epitopes of FliC conserved between strains of Burkholderia: implications for vaccines against melioidosis and cepacia complex in cystic fibrosis.

Musson JA, Reynolds CJ, Rinchai D, Nithichanon A, Khaenam P, Favry E, Spink N, Chu KK, De Soyza A, Bancroft GJ, Lertmemongkolchai G, Maillere B, Boyton RJ, Altmann DM, Robinson JH.

J Immunol. 2014 Dec 15;193(12):6041-9. doi: 10.4049/jimmunol.1402273. Epub 2014 Nov 12.

38.

The serodominant secreted effector protein of Salmonella, SseB, is a strong CD4 antigen containing an immunodominant epitope presented by diverse HLA class II alleles.

Reynolds CJ, Jones C, Blohmke CJ, Darton TC, Goudet A, Sergeant R, Maillere B, Pollard AJ, Altmann DM, Boyton RJ.

Immunology. 2014 Nov;143(3):438-46. doi: 10.1111/imm.12327.

39.

Anthrax lethal factor as an immune target in humans and transgenic mice and the impact of HLA polymorphism on CD4+ T cell immunity.

Ascough S, Ingram RJ, Chu KK, Reynolds CJ, Musson JA, Doganay M, Metan G, Ozkul Y, Baillie L, Sriskandan S, Moore SJ, Gallagher TB, Dyson H, Williamson ED, Robinson JH, Maillere B, Boyton RJ, Altmann DM.

PLoS Pathog. 2014 May 1;10(5):e1004085. doi: 10.1371/journal.ppat.1004085. eCollection 2014 May.

40.

Surveillance for antimicrobial drug resistance in under-resourced countries.

Vernet G, Mary C, Altmann DM, Doumbo O, Morpeth S, Bhutta ZA, Klugman KP.

Emerg Infect Dis. 2014 Mar;20(3):434-41. doi: 10.3201/EID2003.121157. Review.

41.

Injectional anthrax infection due to heroin use induces strong immunological memory.

Ascough S, Ingram RJ, Abarra A, Holmes AJ, Maillere B, Altmann DM, Boyton RJ.

J Infect. 2014 Feb;68(2):200-3. No abstract available.

42.

Peptide-induced immune regulation by a promiscuous and immunodominant CD4T-cell epitope of Timothy grass pollen: a role of Cbl-b and Itch in regulation.

Till SJ, Raynsford EJ, Reynolds CJ, Quigley KJ, Grzybowska-Kowalczyk A, Saggar LR, Goldstone A, Maillere B, Kwok WW, Altmann DM, Durham SR, Boyton RJ.

Thorax. 2014 Apr;69(4):335-45. doi: 10.1136/thoraxjnl-2013-204324. Epub 2013 Nov 20.

43.

Th1 not Th17 cells drive spontaneous MS-like disease despite a functional regulatory T cell response.

Lowther DE, Chong DL, Ascough S, Ettorre A, Ingram RJ, Boyton RJ, Altmann DM.

Acta Neuropathol. 2013 Oct;126(4):501-15. doi: 10.1007/s00401-013-1159-9. Epub 2013 Aug 10.

PMID:
23934116
44.

Exposure to anthrax toxin alters human leucocyte expression of anthrax toxin receptor 1.

Ingram RJ, Harris A, Ascough S, Metan G, Doganay M, Ballie L, Williamson ED, Dyson H, Robinson JH, Sriskandan S, Altmann DM.

Clin Exp Immunol. 2013 Jul;173(1):84-91. doi: 10.1111/cei.12090.

45.

Tuberculosis in London: not unexpected - Authors' reply.

Nicholas R, Dahdaleh D, Altmann DM, Malik O.

Lancet. 2013 Jan 19;381(9862):201-2. doi: 10.1016/S0140-6736(13)60085-9. No abstract available.

PMID:
23332955
46.

Immune mechanisms and the impact of the disrupted lung microbiome in chronic bacterial lung infection and bronchiectasis.

Boyton RJ, Reynolds CJ, Quigley KJ, Altmann DM.

Clin Exp Immunol. 2013 Feb;171(2):117-23. doi: 10.1111/cei.12003. Review.

47.

Immune regulation in idiopathic bronchiectasis.

Boyton RJ, Altmann DM.

Ann N Y Acad Sci. 2012 Dec;1272:68-72. doi: 10.1111/j.1749-6632.2012.06756.x.

PMID:
23231716
48.

Anthrax lethal toxin and the induction of CD4 T cell immunity.

Ascough S, Ingram RJ, Altmann DM.

Toxins (Basel). 2012 Oct;4(10):878-99. doi: 10.3390/toxins4100878. Epub 2012 Oct 19. Review.

49.

Increased HLA-E expression in white matter lesions in multiple sclerosis.

Durrenberger PF, Webb LV, Sim MJ, Nicholas RS, Altmann DM, Boyton RJ.

Immunology. 2012 Dec;137(4):317-25. doi: 10.1111/imm.12012.

50.

Breathlessness, night sweats, and weight loss on natalizumab.

Dahdaleh D, Altmann DM, Malik O, Nicholas RS.

Lancet. 2012 Aug 25;380(9843):726-7. doi: 10.1016/S0140-6736(12)61401-9. No abstract available.

PMID:
22920745

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