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Items: 1 to 50 of 159

1.

Mamu-B*17+ rhesus macaques vaccinated with env, vif, and nef manifest early control of SIVmac239 replication.

Martins MA, Tully DC, Pedreño-Lopez N, von Bredow B, Pauthner MG, Shin YC, Yuan M, Lima NS, Bean DJ, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Magnani DM, Ricciardi MJ, Bailey VK, Altman JD, Burton DR, Ejima K, Allison DB, Evans DT, Rakasz EG, Parks CL, Bonaldo MC, Capuano S 3rd, Lifson JD, Desrosiers RC, Allen TM, Watkins DI.

J Virol. 2018 Jun 6. pii: JVI.00690-18. doi: 10.1128/JVI.00690-18. [Epub ahead of print]

PMID:
29875239
2.

Empty conformers of HLA-B preferentially bind CD8 and regulate CD8+ T cell function.

Geng J, Altman JD, Krishnakumar S, Raghavan M.

Elife. 2018 May 9;7. pii: e36341. doi: 10.7554/eLife.36341.

3.

A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in Human Mycobacterium tuberculosis Infection.

Whatney WE, Gandhi NR, Lindestam Arlehamn CS, Nizam A, Wu H, Quezada MJ, Campbell A, Allana S, Kabongo MM, Khayumbi J, Muchiri B, Ongalo J, Tonui J, Sasser LE, Fergus TJ, Ouma GS, Ouma SG, Beck AA, Mulligan MJ, Oladele A, Kaushal D, Cain KP, Waller L, Blumberg HM, Altman JD, Ernst JD, Rengarajan J, Day CL; TBRU-ASTRa Study Group.

J Immunol. 2018 Apr 15;200(8):3008-3019. doi: 10.4049/jimmunol.1701737. Epub 2018 Mar 14.

PMID:
29540577
4.

T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.

Wun KS, Reijneveld JF, Cheng TY, Ladell K, Uldrich AP, Le Nours J, Miners KL, McLaren JE, Grant EJ, Haigh OL, Watkins TS, Suliman S, Iwany S, Jimenez J, Calderon R, Tamara KL, Leon SR, Murray MB, Mayfield JA, Altman JD, Purcell AW, Miles JJ, Godfrey DI, Gras S, Price DA, Van Rhijn I, Moody DB, Rossjohn J.

Nat Immunol. 2018 Apr;19(4):397-406. doi: 10.1038/s41590-018-0065-7. Epub 2018 Mar 12.

PMID:
29531339
5.

Synthesis, stabilization, and characterization of the MR1 ligand precursor 5-amino-6-D-ribitylaminouracil (5-A-RU).

Li K, Vorkas CK, Chaudhry A, Bell DL, Willis RA, Rudensky A, Altman JD, Glickman MS, Aubé J.

PLoS One. 2018 Feb 5;13(2):e0191837. doi: 10.1371/journal.pone.0191837. eCollection 2018.

6.

Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques.

Martins MA, Shin YC, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Castro I, Magnani DM, Ricciardi M, Pedreño-Lopez N, Bailey V, Betancourt D, Altman JD, Pauthner M, Burton DR, von Bredow B, Evans DT, Yuan M, Parks CL, Ejima K, Allison DB, Rakasz E, Barber GN, Capuano S 3rd, Lifson JD, Desrosiers RC, Watkins DI.

PLoS Pathog. 2017 Jul 21;13(7):e1006529. doi: 10.1371/journal.ppat.1006529. eCollection 2017 Jul.

7.

Rare Control of SIVmac239 Infection in a Vaccinated Rhesus Macaque.

Martins MA, Tully DC, Shin YC, Gonzalez-Nieto L, Weisgrau KL, Bean DJ, Gadgil R, Gutman MJ, Domingues A, Maxwell HS, Magnani DM, Ricciardi M, Pedreño-Lopez N, Bailey V, Cruz MA, Lima NS, Bonaldo MC, Altman JD, Rakasz E, Capuano S 3rd, Reimann KA, Piatak M Jr, Lifson JD, Desrosiers RC, Allen TM, Watkins DI.

AIDS Res Hum Retroviruses. 2017 Aug;33(8):843-858. doi: 10.1089/AID.2017.0046. Epub 2017 Jun 29.

PMID:
28503929
8.

MHC-Peptide Tetramers to Visualize Antigen-Specific T Cells.

Altman JD, Davis MM.

Curr Protoc Immunol. 2016 Nov 1;115:17.3.1-17.3.44. doi: 10.1002/cpim.14.

PMID:
27801510
9.

Molecular Analysis of Lipid-Reactive Vδ1 γδ T Cells Identified by CD1c Tetramers.

Roy S, Ly D, Castro CD, Li NS, Hawk AJ, Altman JD, Meredith SC, Piccirilli JA, Moody DB, Adams EJ.

J Immunol. 2016 Feb 15;196(4):1933-42. doi: 10.4049/jimmunol.1502202. Epub 2016 Jan 11.

10.

Human autoreactive T cells recognize CD1b and phospholipids.

Van Rhijn I, van Berlo T, Hilmenyuk T, Cheng TY, Wolf BJ, Tatituri RV, Uldrich AP, Napolitani G, Cerundolo V, Altman JD, Willemsen P, Huang S, Rossjohn J, Besra GS, Brenner MB, Godfrey DI, Moody DB.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):380-5. doi: 10.1073/pnas.1520947112. Epub 2015 Nov 30.

11.

Vaccine-Induced Simian Immunodeficiency Virus-Specific CD8+ T-Cell Responses Focused on a Single Nef Epitope Select for Escape Variants Shortly after Infection.

Martins MA, Tully DC, Cruz MA, Power KA, Veloso de Santana MG, Bean DJ, Ogilvie CB, Gadgil R, Lima NS, Magnani DM, Ejima K, Allison DB, Piatak M Jr, Altman JD, Parks CL, Rakasz EG, Capuano S 3rd, Galler R, Bonaldo MC, Lifson JD, Allen TM, Watkins DI.

J Virol. 2015 Nov;89(21):10802-20. doi: 10.1128/JVI.01440-15. Epub 2015 Aug 19.

12.

Prospective Assessment of the Diagnostic Accuracy of Instantaneous Wave-Free Ratio to Assess Coronary Stenosis Relevance: Results of ADVISE II International, Multicenter Study (ADenosine Vasodilator Independent Stenosis Evaluation II).

Escaned J, Echavarría-Pinto M, Garcia-Garcia HM, van de Hoef TP, de Vries T, Kaul P, Raveendran G, Altman JD, Kurz HI, Brechtken J, Tulli M, Von Birgelen C, Schneider JE, Khashaba AA, Jeremias A, Baucum J, Moreno R, Meuwissen M, Mishkel G, van Geuns RJ, Levite H, Lopez-Palop R, Mayhew M, Serruys PW, Samady H, Piek JJ, Lerman A; ADVISE II Study Group.

JACC Cardiovasc Interv. 2015 May;8(6):824-833. doi: 10.1016/j.jcin.2015.01.029.

13.

Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by αβ T cells.

Roy S, Ly D, Li NS, Altman JD, Piccirilli JA, Moody DB, Adams EJ.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4648-57. doi: 10.1073/pnas.1408549111. Epub 2014 Oct 8.

14.

CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens.

de Jong A, Cheng TY, Huang S, Gras S, Birkinshaw RW, Kasmar AG, Van Rhijn I, Peña-Cruz V, Ruan DT, Altman JD, Rossjohn J, Moody DB.

Nat Immunol. 2014 Feb;15(2):177-85. doi: 10.1038/ni.2790. Epub 2013 Dec 22.

15.

Cutting Edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo.

Kasmar AG, Van Rhijn I, Magalhaes KG, Young DC, Cheng TY, Turner MT, Schiefner A, Kalathur RC, Wilson IA, Bhati M, Gras S, Birkinshaw RW, Tan LL, Rossjohn J, Shires J, Jakobsen S, Altman JD, Moody DB.

J Immunol. 2013 Nov 1;191(9):4499-503. doi: 10.4049/jimmunol.1301660. Epub 2013 Oct 2.

16.

A conserved human T cell population targets mycobacterial antigens presented by CD1b.

Van Rhijn I, Kasmar A, de Jong A, Gras S, Bhati M, Doorenspleet ME, de Vries N, Godfrey DI, Altman JD, de Jager W, Rossjohn J, Moody DB.

Nat Immunol. 2013 Jul;14(7):706-13. doi: 10.1038/ni.2630. Epub 2013 Jun 2.

17.

CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens.

Ly D, Kasmar AG, Cheng TY, de Jong A, Huang S, Roy S, Bhatt A, van Summeren RP, Altman JD, Jacobs WR Jr, Adams EJ, Minnaard AJ, Porcelli SA, Moody DB.

J Exp Med. 2013 Apr 8;210(4):729-41. doi: 10.1084/jem.20120624. Epub 2013 Mar 25.

18.

CD8 T cell memory recall is enhanced by novel direct interactions with CD4 T cells enabled by MHC class II transferred from APCs.

Romagnoli PA, Premenko-Lanier MF, Loria GD, Altman JD.

PLoS One. 2013;8(2):e56999. doi: 10.1371/journal.pone.0056999. Epub 2013 Feb 18.

19.

Deletion of specific immune-modulatory genes from modified vaccinia virus Ankara-based HIV vaccines engenders improved immunogenicity in rhesus macaques.

Garber DA, O'Mara LA, Gangadhara S, McQuoid M, Zhang X, Zheng R, Gill K, Verma M, Yu T, Johnson B, Li B, Derdeyn CA, Ibegbu C, Altman JD, Hunter E, Feinberg MB.

J Virol. 2012 Dec;86(23):12605-15. doi: 10.1128/JVI.00246-12. Epub 2012 Sep 12.

20.

Platelets support a protective immune response to LCMV by preventing splenic necrosis.

Loria GD, Romagnoli PA, Moseley NB, Rucavado A, Altman JD.

Blood. 2013 Feb 7;121(6):940-50. doi: 10.1182/blood-2011-08-376822. Epub 2012 May 7.

21.

Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system.

Huang S, Cheng TY, Young DC, Layre E, Madigan CA, Shires J, Cerundolo V, Altman JD, Moody DB.

Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19335-40. doi: 10.1073/pnas.1112969108. Epub 2011 Nov 15.

22.

Use of replication restricted recombinant vesicular stomatitis virus vectors for detection of antigen-specific T cells.

Moseley NB, Laur O, Ibegbu CC, Loria GD, Ikwuenzunma G, Jayakar HR, Whitt MA, Altman JD.

J Immunol Methods. 2012 Jan 31;375(1-2):118-28. doi: 10.1016/j.jim.2011.09.016. Epub 2011 Oct 8.

23.

CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans.

Kasmar AG, van Rhijn I, Cheng TY, Turner M, Seshadri C, Schiefner A, Kalathur RC, Annand JW, de Jong A, Shires J, Leon L, Brenner M, Wilson IA, Altman JD, Moody DB.

J Exp Med. 2011 Aug 29;208(9):1741-7. doi: 10.1084/jem.20110665. Epub 2011 Aug 1.

24.

Interrogating the repertoire: broadening the scope of peptide-MHC multimer analysis.

Davis MM, Altman JD, Newell EW.

Nat Rev Immunol. 2011 Jul 15;11(8):551-8. doi: 10.1038/nri3020. Review.

25.

Phenotypic analysis of antigen-specific T lymphocytes. Science. 1996. 274: 94-96.

Altman JD, Moss PA, Goulder PJ, Barouch DH, McHeyzer-Williams MG, Bell JI, McMichael AJ, Davis MM.

J Immunol. 2011 Jul 1;187(1):7-9. No abstract available.

26.

The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response.

Akondy RS, Monson ND, Miller JD, Edupuganti S, Teuwen D, Wu H, Quyyumi F, Garg S, Altman JD, Del Rio C, Keyserling HL, Ploss A, Rice CM, Orenstein WA, Mulligan MJ, Ahmed R.

J Immunol. 2009 Dec 15;183(12):7919-30. doi: 10.4049/jimmunol.0803903.

27.

New design of MHC class II tetramers to accommodate fundamental principles of antigen presentation.

Landais E, Romagnoli PA, Corper AL, Shires J, Altman JD, Wilson IA, Garcia KC, Teyton L.

J Immunol. 2009 Dec 15;183(12):7949-57. doi: 10.4049/jimmunol.0902493.

28.

Vaccine-induced, simian immunodeficiency virus-specific CD8+ T cells reduce virus replication but do not protect from simian immunodeficiency virus disease progression.

Engram JC, Dunham RM, Makedonas G, Vanderford TH, Sumpter B, Klatt NR, Ratcliffe SJ, Garg S, Paiardini M, McQuoid M, Altman JD, Staprans SI, Betts MR, Garber DA, Feinberg MB, Silvestri G.

J Immunol. 2009 Jul 1;183(1):706-17. doi: 10.4049/jimmunol.0803746.

29.

IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection.

Sereti I, Dunham RM, Spritzler J, Aga E, Proschan MA, Medvik K, Battaglia CA, Landay AL, Pahwa S, Fischl MA, Asmuth DM, Tenorio AR, Altman JD, Fox L, Moir S, Malaspina A, Morre M, Buffet R, Silvestri G, Lederman MM; ACTG 5214 Study Team.

Blood. 2009 Jun 18;113(25):6304-14. doi: 10.1182/blood-2008-10-186601. Epub 2009 Apr 20.

30.

Comparisons of CD8+ T cells specific for human immunodeficiency virus, hepatitis C virus, and cytomegalovirus reveal differences in frequency, immunodominance, phenotype, and interleukin-2 responsiveness.

Jagannathan P, Osborne CM, Royce C, Manion MM, Tilton JC, Li L, Fischer S, Hallahan CW, Metcalf JA, McLaughlin M, Pipeling M, McDyer JF, Manley TJ, Meier JL, Altman JD, Hertel L, Davey RT Jr, Connors M, Migueles SA.

J Virol. 2009 Mar;83(6):2728-42. doi: 10.1128/JVI.02128-08. Epub 2009 Jan 7.

31.

Transient FTY720 treatment promotes immune-mediated clearance of a chronic viral infection.

Premenko-Lanier M, Moseley NB, Pruett ST, Romagnoli PA, Altman JD.

Nature. 2008 Aug 14;454(7206):894-8. doi: 10.1038/nature07199. Retraction in: Nature. 2010 Apr 8;464(7290):942.

PMID:
18704087
32.

Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines.

Miller JD, van der Most RG, Akondy RS, Glidewell JT, Albott S, Masopust D, Murali-Krishna K, Mahar PL, Edupuganti S, Lalor S, Germon S, Del Rio C, Mulligan MJ, Staprans SI, Altman JD, Feinberg MB, Ahmed R.

Immunity. 2008 May;28(5):710-22. doi: 10.1016/j.immuni.2008.02.020. Epub 2008 May 8.

33.

MHC-peptide tetramers to visualize antigen-specific T cells.

Altman JD, Davis MM.

Curr Protoc Immunol. 2003 May;Chapter 17:Unit 17.3. doi: 10.1002/0471142735.im1703s53. Review.

PMID:
18432902
34.

Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part I: Panel design by an empiric approach.

McLaughlin BE, Baumgarth N, Bigos M, Roederer M, De Rosa SC, Altman JD, Nixon DF, Ottinger J, Oxford C, Evans TG, Asmuth DM.

Cytometry A. 2008 May;73(5):400-10. doi: 10.1002/cyto.a.20555.

35.

Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part II: Panel performance across different instrument platforms.

McLaughlin BE, Baumgarth N, Bigos M, Roederer M, De Rosa SC, Altman JD, Nixon DF, Ottinger J, Li J, Beckett L, Shacklett BL, Evans TG, Asmuth DM.

Cytometry A. 2008 May;73(5):411-20. doi: 10.1002/cyto.a.20556.

36.
37.

IL-15 treatment during acute simian immunodeficiency virus (SIV) infection increases viral set point and accelerates disease progression despite the induction of stronger SIV-specific CD8+ T cell responses.

Mueller YM, Do DH, Altork SR, Artlett CM, Gracely EJ, Katsetos CD, Legido A, Villinger F, Altman JD, Brown CR, Lewis MG, Katsikis PD.

J Immunol. 2008 Jan 1;180(1):350-60.

38.

Memory CD8+ T cells require CD28 costimulation.

Borowski AB, Boesteanu AC, Mueller YM, Carafides C, Topham DJ, Altman JD, Jennings SR, Katsikis PD.

J Immunol. 2007 Nov 15;179(10):6494-503.

39.

Actin integrity is indispensable for CD95/Fas-induced apoptosis of HIV-specific CD8+ T cells.

Petrovas C, Mueller YM, Yang G, Altork SR, Jacobson JM, Pitsakis PG, Mounzer KC, Altman JD, Katsikis PD.

Apoptosis. 2007 Dec;12(12):2175-86.

PMID:
17891455
40.

Early establishment and antigen dependence of simian immunodeficiency virus-specific CD8+ T-cell defects.

Mueller YM, Petrovas C, Do DH, Altork SR, Fischer-Smith T, Rappaport J, Altman JD, Lewis MG, Katsikis PD.

J Virol. 2007 Oct;81(20):10861-8. Epub 2007 Aug 1.

41.
42.

A robust method for production of MHC tetramers with small molecule fluorophores.

Ramachandiran V, Grigoriev V, Lan L, Ravkov E, Mertens SA, Altman JD.

J Immunol Methods. 2007 Jan 30;319(1-2):13-20. Epub 2006 Sep 22.

43.

Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression.

Radziewicz H, Ibegbu CC, Fernandez ML, Workowski KA, Obideen K, Wehbi M, Hanson HL, Steinberg JP, Masopust D, Wherry EJ, Altman JD, Rouse BT, Freeman GJ, Ahmed R, Grakoui A.

J Virol. 2007 Mar;81(6):2545-53. Epub 2006 Dec 20.

44.

Increased mitochondrial mass characterizes the survival defect of HIV-specific CD8(+) T cells.

Petrovas C, Mueller YM, Dimitriou ID, Altork SR, Banerjee A, Sklar P, Mounzer KC, Altman JD, Katsikis PD.

Blood. 2007 Mar 15;109(6):2505-13. Epub 2006 Nov 9.

45.

A modified alpha-galactosyl ceramide for staining and stimulating natural killer T cells.

Liu Y, Goff RD, Zhou D, Mattner J, Sullivan BA, Khurana A, Cantu C 3rd, Ravkov EV, Ibegbu CC, Altman JD, Teyton L, Bendelac A, Savage PB.

J Immunol Methods. 2006 May 30;312(1-2):34-9. Epub 2006 Mar 6.

PMID:
16647712
46.

Effects of inedible, manipulable objects on captive bears.

Altman JD.

J Appl Anim Welf Sci. 1999;2(2):123-32.

PMID:
16363951
47.

Comparison of IgG reactivities to Plasmodium vivax merozoite invasion antigens in a Brazilian Amazon population.

Tran TM, Oliveira-Ferreira J, Moreno A, Santos F, Yazdani SS, Chitnis CE, Altman JD, Meyer EV, Barnwell JW, Galinski MR.

Am J Trop Med Hyg. 2005 Aug;73(2):244-55.

PMID:
16103583
48.

Nutritional and behavioral effects of gorge and fast feeding in captive lions.

Altman JD, Gross KL, Lowry SR.

J Appl Anim Welf Sci. 2005;8(1):47-57.

PMID:
16004544
49.

Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals.

Paiardini M, Cervasi B, Albrecht H, Muthukumar A, Dunham R, Gordon S, Radziewicz H, Piedimonte G, Magnani M, Montroni M, Kaech SM, Weintrob A, Altman JD, Sodora DL, Feinberg MB, Silvestri G.

J Immunol. 2005 Mar 1;174(5):2900-9.

50.

Kinetics of expansion of SIV Gag-specific CD8+ T lymphocytes following challenge of vaccinated macaques.

Abdel-Motal UM, Gillis J, Manson K, Wyand M, Montefiori D, Stefano-Cole K, Montelaro RC, Altman JD, Johnson RP.

Virology. 2005 Mar 15;333(2):226-38.

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