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Items: 47

1.

Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling.

Chen CW, Beyer C, Liu J, Maier C, Li C, Trinh-Minh T, Xu X, Cole SH, Hsieh MH, Ng N, Althage A, Meeusen S, Pan S, Svensson EC, Seidel HM, Schett G, Gergely P, Harris JL, Distler JH.

Ann Rheum Dis. 2017 Apr;76(4):773-778. doi: 10.1136/annrheumdis-2016-210294. Epub 2017 Feb 2.

PMID:
28153829
2.

Enhanced proteolytic clearance of plasma Aβ by peripherally administered neprilysin does not result in reduced levels of brain Aβ in mice.

Walker JR, Pacoma R, Watson J, Ou W, Alves J, Mason DE, Peters EC, Urbina HD, Welzel G, Althage A, Liu B, Tuntland T, Jacobson LH, Harris JL, Schumacher AM.

J Neurosci. 2013 Feb 6;33(6):2457-64. doi: 10.1523/JNEUROSCI.3407-12.2013.

3.

A stem cell-based approach to cartilage repair.

Johnson K, Zhu S, Tremblay MS, Payette JN, Wang J, Bouchez LC, Meeusen S, Althage A, Cho CY, Wu X, Schultz PG.

Science. 2012 May 11;336(6082):717-21. doi: 10.1126/science.1215157. Epub 2012 Apr 5.

4.

Immune effectors required for hepatitis B virus clearance.

Yang PL, Althage A, Chung J, Maier H, Wieland S, Isogawa M, Chisari FV.

Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):798-802. doi: 10.1073/pnas.0913498107. Epub 2009 Dec 22.

5.

Transient expression of an IL-23R extracellular domain Fc fusion protein in CHO vs. HEK cells results in improved plasma exposure.

Suen KF, Turner MS, Gao F, Liu B, Althage A, Slavin A, Ou W, Zuo E, Eckart M, Ogawa T, Yamada M, Tuntland T, Harris JL, Trauger JW.

Protein Expr Purif. 2010 May;71(1):96-102. doi: 10.1016/j.pep.2009.12.015. Epub 2010 Jan 4.

PMID:
20045465
6.

Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs.

Uprichard SL, Boyd B, Althage A, Chisari FV.

Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):773-8. Epub 2005 Jan 7.

7.

Efficient T cell repertoire selection in tetraparental chimeric mice independent of thymic epithelial MHC.

Martinic MM, Rülicke T, Althage A, Odermatt B, Höchli M, Lamarre A, Dumrese T, Speiser DE, Kyburz D, Hengartner H, Zinkernagel RM.

Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1861-6. Epub 2003 Feb 6.

8.

Transcriptional and posttranscriptional control of hepatitis B virus gene expression.

Uprichard SL, Wieland SF, Althage A, Chisari FV.

Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1310-5. Epub 2003 Jan 27.

9.

Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection.

Yang PL, Althage A, Chung J, Chisari FV.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13825-30. Epub 2002 Oct 8.

10.

Allogeneic beta-islet cells correct diabetes and resist immune rejection.

Pericin M, Althage A, Freigang S, Hengartner H, Rolland E, Dupraz P, Thorens B, Aebischer P, Zinkernagel RM.

Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8203-6.

11.

Immunodeficiency of alymphoplasia mice (aly/aly) in vivo: structural defect of secondary lymphoid organs and functional B cell defect.

Karrer U, Althage A, Odermatt B, Hengartner H, Zinkernagel RM.

Eur J Immunol. 2000 Oct;30(10):2799-807.

12.

A comparison of T cell memory against the same antigen induced by virus versus intracellular bacteria.

Ochsenbein AF, Karrer U, Klenerman P, Althage A, Ciurea A, Shen H, Miller JF, Whitton JL, Hengartner H, Zinkernagel RM.

Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9293-8.

13.

On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells.

Zinkernagel RM, Althage A.

Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):8092-7.

14.

The role of antibody concentration and avidity in antiviral protection.

Bachmann MF, Kalinke U, Althage A, Freer G, Burkhart C, Roost H, Aguet M, Hengartner H, Zinkernagel RM.

Science. 1997 Jun 27;276(5321):2024-7.

15.

On the key role of secondary lymphoid organs in antiviral immune responses studied in alymphoplastic (aly/aly) and spleenless (Hox11(-)/-) mutant mice.

Karrer U, Althage A, Odermatt B, Roberts CW, Korsmeyer SJ, Miyawaki S, Hengartner H, Zinkernagel RM.

J Exp Med. 1997 Jun 16;185(12):2157-70.

16.

Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3'-long terminal repeat transgene.

Lindemann D, Wilhelm R, Renard P, Althage A, Zinkernagel R, Mous J.

J Exp Med. 1994 Mar 1;179(3):797-807.

17.

Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes.

Rothe J, Lesslauer W, Lötscher H, Lang Y, Koebel P, Köntgen F, Althage A, Zinkernagel R, Steinmetz M, Bluethmann H.

Nature. 1993 Aug 26;364(6440):798-802.

PMID:
8395024
18.

Immune response in mice that lack the interferon-gamma receptor.

Huang S, Hendriks W, Althage A, Hemmi S, Bluethmann H, Kamijo R, Vilcek J, Zinkernagel RM, Aguet M.

Science. 1993 Mar 19;259(5102):1742-5.

PMID:
8456301
19.

Skin test to assess virus-specific cytotoxic T-cell activity.

Kündig TM, Althage A, Hengartner H, Zinkernagel RM.

Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7757-61.

20.

Immunosuppression by lymphocytic choriomeningitis virus infection: competent effector T and B cells but impaired antigen presentation.

Althage A, Odermatt B, Moskophidis D, Kündig T, Hoffman-Rohrer U, Hengartner H, Zinkernagel RM.

Eur J Immunol. 1992 Jul;22(7):1803-12.

PMID:
1623925
21.

Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates.

Battegay M, Cooper S, Althage A, Bänziger J, Hengartner H, Zinkernagel RM.

J Virol Methods. 1991 Jun;33(1-2):191-8. Erratum in: J Virol Methods. 1991 Nov;35(1):115. J Virol Methods. 1992 Aug;38(2):263.

PMID:
1939506
22.
23.

Antiviral T cell competence and restriction specificity of mixed allogeneic (P1 + P2----P1) irradiation chimeras.

Rüedi E, Sykes M, Ildstad ST, Chester CH, Althage A, Hengartner H, Sachs DH, Zinkernagel RM.

Cell Immunol. 1989 Jun;121(1):185-95.

PMID:
2470518
24.
25.

An acquired immune suppression in mice caused by infection with lymphocytic choriomeningitis virus.

Roost H, Charan S, Gobet R, Rüedi E, Hengartner H, Althage A, Zinkernagel RM.

Eur J Immunol. 1988 Apr;18(4):511-8.

PMID:
2452742
26.

An easy and rapid method to screen large numbers of antibodies against internal cellular determinants.

Stitz L, Hengartner H, Althage A, Zinkernagel RM.

J Immunol Methods. 1988 Feb 10;106(2):211-6.

PMID:
3276792
29.

Susceptibility to murine lymphocytic choriomeningitis maps to class I MHC genes--a model for MHC/disease associations.

Zinkernagel RM, Pfau CJ, Hengartner H, Althage A.

Nature. 1985 Aug 29-Sep 4;316(6031):814-7.

PMID:
4033780
30.

Natural killer cells vs cytotoxic T cells in the peripheral blood of virus-infected mice.

Stitz L, Althage A, Hengartner H, Zinkernagel R.

J Immunol. 1985 Jan;134(1):598-602.

PMID:
2981094
31.
32.

Thymus differentiation and T-cell specificity in nu/nu +/+ mouse aggregation chimaeras.

Zinkernagel RM, Bürki K, Cottier F, de Kossodo S, Althage A, Illmensee K.

EMBO J. 1983;2(10):1665-72.

33.
34.

On the immunocompetence of H-2 incompatible irradiation bone marrow chimeras.

Zinkernagel RM, Althage A, Callahan G, Welsh RM Jr.

J Immunol. 1980 May;124(5):2356-65. No abstract available.

PMID:
6444970
35.

Lymphohemopoietic origin of the immunogenic, virus-antigen-presenting cells triggering anti-viral T-cell responses.

Zinkernagel RM, Kreeb G, Althage A.

Clin Immunol Immunopathol. 1980 Mar;15(3):565-76. No abstract available.

PMID:
6966204
36.

Restriction specificities, alloreactivity, and allotolerance expressed by T cells from nude mice reconstituted with H-2-compatible or -incompatible thymus grafts.

Zinkernagel RM, Althage A, Waterfield E, Kindred B, Welsh RM, Callahan G, Pincetl P.

J Exp Med. 1980 Feb 1;151(2):376-99.

37.

Thymic reconstitution of nude F1 mice with one or both parental thymus grafts.

Zinkernagel RM, Althage A, Callahan G.

J Exp Med. 1979 Sep 19;150(3):693-7.

38.

Search for suppression of T cells specific for the second nonhost H-2 haplotype in F1 leads to P irradiation bone marrow chimeras.

Zinkernagel RM, Althage A.

J Immunol. 1979 May;122(5):1742-9. No abstract available.

PMID:
156219
39.
40.

Ir-genes in H-2 regulate generation of anti-viral cytotoxic T cells. Mapping to K or D and dominance of unresponsiveness.

Zinkernagel RM, Althage A, Cooper S, Kreeb G, Klein PA, Sefton B, Flaherty L, Stimpfling J, Shreffler D, Klein J.

J Exp Med. 1978 Aug 1;148(2):592-606.

41.

Target antigens for H-2-restricted vesicular stomatitis virus-specific cytotoxic T cells.

Zinkernagel RM, Althage A, Holland J.

J Immunol. 1978 Aug;121(2):744-8.

PMID:
210232
42.

Cell-mediated immunity to viruses in hamsters.

Zinkernagel RM, Althage A, Jensen F, Streilein JW, Duncan WR.

Fed Proc. 1978 May 15;37(7):2078-81. No abstract available.

PMID:
640020
43.

The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help.

Zinkernagel RM, Callahan GN, Althage A, Cooper S, Streilein JW, Klein J.

J Exp Med. 1978 Mar 1;147(3):897-911.

44.

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

Zinkernagel RM, Callahan GN, Althage A, Cooper S, Klein PA, Klein J.

J Exp Med. 1978 Mar 1;147(3):882-96.

45.

Cell-mediated immune response to lymphocytic choriomeningitis and vaccinia virus in rats.

Zinkernagel RM, Althage A, Jensen FC.

J Immunol. 1977 Oct;119(4):1242-7.

PMID:
408419
46.

H-2 restriction of cell-mediated immunity to an intracellular bacterium: effector T cells are specific for Listeria antigen in association with H-21 region-coded self-markers.

Zinkernagel RM, Althage A, Adler B, Blanden RV, Davidson WF, Kees U, Dunlop MB, Shreffler DC.

J Exp Med. 1977 May 1;145(5):1353-67.

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