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Items: 1 to 50 of 259

1.

CD49a Expression Identifies a Subset of Intrahepatic Macrophages in Humans.

Martrus G, Goebels H, Langeneckert AE, Kah J, Flomm F, Ziegler AE, Niehrs A, Löbl SM, Russu K, Hess LU, Salzberger W, Poch T, Nashan B, Schramm C, Oldhafer KJ, Dandri M, Koch M, Lunemann S, Altfeld M.

Front Immunol. 2019 Jun 7;10:1247. doi: 10.3389/fimmu.2019.01247. eCollection 2019.

2.

Interferon-γ-dependent immune responses contribute to the pathogenesis of sclerosing cholangitis in mice.

Ravichandran G, Neumann K, Berkhout LK, Weidemann S, Langeneckert AE, Schwinge D, Poch T, Huber S, Schiller B, Hess LU, Ziegler AE, Oldhafer KJ, Barikbin R, Schramm C, Altfeld M, Tiegs G.

J Hepatol. 2019 Jun 5. pii: S0168-8278(19)30309-5. doi: 10.1016/j.jhep.2019.05.023. [Epub ahead of print]

PMID:
31173810
3.

Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine.

Sagebiel AF, Steinert F, Lunemann S, Körner C, Schreurs RRCE, Altfeld M, Perez D, Reinshagen K, Bunders MJ.

Nat Commun. 2019 Feb 28;10(1):975. doi: 10.1038/s41467-018-08267-7.

4.

CCL21-expression and accumulation of CCR7+ NK cells in livers of patients with primary sclerosing cholangitis.

Langeneckert AE, Lunemann S, Martrus G, Salzberger W, Hess LU, Ziegler AE, Poch T, Ravichandran G, Matschl U, Bosse JB, Tiegs G, Fischer L, Koch M, Herkel J, Oldhafer KJ, Schramm C, Altfeld M.

Eur J Immunol. 2019 May;49(5):758-769. doi: 10.1002/eji.201847965. Epub 2019 Feb 27.

PMID:
30785638
5.

Human liver-derived CXCR6+ NK cells are predominantly educated through NKG2A and show reduced cytokine production.

Lunemann S, Langeneckert AE, Martrus G, Hess LU, Salzberger W, Ziegler AE, Löbl SM, Poch T, Ravichandran G, Sauter J, Schmidt AH, Schramm C, Oldhafer KJ, Altfeld M, Körner C.

J Leukoc Biol. 2019 Jun;105(6):1331-1340. doi: 10.1002/JLB.1MA1118-428R. Epub 2019 Feb 19.

PMID:
30779432
6.

Sex differences in immunity.

Lotter H, Altfeld M.

Semin Immunopathol. 2019 Mar;41(2):133-135. doi: 10.1007/s00281-018-00728-x. Epub 2019 Feb 11. No abstract available.

PMID:
30742253
7.

Natural Killer Cell Education Is Associated With a Distinct Glycolytic Profile.

Pfeifer C, Highton AJ, Peine S, Sauter J, Schmidt AH, Bunders MJ, Altfeld M, Körner C.

Front Immunol. 2018 Dec 19;9:3020. doi: 10.3389/fimmu.2018.03020. eCollection 2018.

8.

Stable Frequencies of HLA-C*03:04/Peptide-Binding KIR2DL2/3+ Natural Killer Cells Following Vaccination.

Ziegler MC, Grañana FB, Garcia-Beltran WF, Schulze Zur Wiesch J, Hoffmann C, Rechtien A, Lunemann S, Altfeld M.

Front Immunol. 2018 Oct 17;9:2361. doi: 10.3389/fimmu.2018.02361. eCollection 2018.

9.

Sex-Based Differences in Human Immunodeficiency Virus Type 1 Reservoir Activity and Residual Immune Activation.

Scully EP, Gandhi M, Johnston R, Hoh R, Lockhart A, Dobrowolski C, Pagliuzza A, Milush JM, Baker CA, Girling V, Ellefson A, Gorelick R, Lifson J, Altfeld M, Alter G, Cedars M, Solomon A, Lewin SR, Karn J, Chomont N, Bacchetti P, Deeks SG.

J Infect Dis. 2019 Mar 15;219(7):1084-1094. doi: 10.1093/infdis/jiy617.

PMID:
30371873
10.

Sexual dimorphism in HIV-1 infection.

Rechtien A, Altfeld M.

Semin Immunopathol. 2019 Mar;41(2):195-202. doi: 10.1007/s00281-018-0704-y. Epub 2018 Oct 1. Review.

PMID:
30276445
11.

Interactions Between KIR3DS1 and HLA-F Activate Natural Killer Cells to Control HCV Replication in Cell Culture.

Lunemann S, Schöbel A, Kah J, Fittje P, Hölzemer A, Langeneckert AE, Hess LU, Poch T, Martrus G, Garcia-Beltran WF, Körner C, Ziegler AE, Richert L, Oldhafer KJ, Schulze Zur Wiesch J, Schramm C, Dandri M, Herker E, Altfeld M.

Gastroenterology. 2018 Nov;155(5):1366-1371.e3. doi: 10.1053/j.gastro.2018.07.019. Epub 2018 Jul 19.

PMID:
30031767
12.

Tissue-resident NK cells differ in their expression profile of the nutrient transporters Glut1, CD98 and CD71.

Salzberger W, Martrus G, Bachmann K, Goebels H, Heß L, Koch M, Langeneckert A, Lunemann S, Oldhafer KJ, Pfeifer C, Poch T, Richert L, Schramm C, Wahib R, Bunders MJ, Altfeld M.

PLoS One. 2018 Jul 20;13(7):e0201170. doi: 10.1371/journal.pone.0201170. eCollection 2018.

13.

Innate immune responses to toll-like receptor stimulation are altered during the course of pregnancy.

Ziegler SM, Feldmann CN, Hagen SH, Richert L, Barkhausen T, Goletzke J, Jazbutyte V, Martrus G, Salzberger W, Renné T, Hecher K, Diemert A, Arck PC, Altfeld M.

J Reprod Immunol. 2018 Aug;128:30-37. doi: 10.1016/j.jri.2018.05.009. Epub 2018 May 24.

PMID:
29886307
14.

Carcinoembryonic antigen-related cell adhesion molecule 1 controls IL-2-dependent regulatory T-cell induction in immune-mediated hepatitis in mice.

Horst AK, Wegscheid C, Schaefers C, Schiller B, Neumann K, Lunemann S, Langeneckert AE, Oldhafer KJ, Weiler-Normann C, Lang KS, Singer BB, Altfeld M, Diehl L, Tiegs G.

Hepatology. 2018 Jul;68(1):200-214. doi: 10.1002/hep.29812. Epub 2018 May 14.

PMID:
29377208
15.

Is There Natural Killer Cell Memory and Can It Be Harnessed by Vaccination? Can Natural Killer and CD8 T Cells Switch Jobs?

Biron CA, Altfeld M.

Cold Spring Harb Perspect Biol. 2018 Oct 1;10(10). pii: a029892. doi: 10.1101/cshperspect.a029892. Review.

PMID:
29254975
16.

Natural Killer Cell Interactions with Classical and Non-Classical Human Leukocyte Antigen Class I in HIV-1 Infection.

Hölzemer A, Garcia-Beltran WF, Altfeld M.

Front Immunol. 2017 Nov 14;8:1496. doi: 10.3389/fimmu.2017.01496. eCollection 2017. Review.

17.

Can NK cells purge HIV sanctuaries?

Bunders MJ, Altfeld M.

Nat Med. 2017 Nov 7;23(11):1254-1255. doi: 10.1038/nm.4434. No abstract available.

PMID:
29117170
18.

Human Immunodeficiency Virus 1 and Type I Interferons-Where Sex Makes a Difference.

Ziegler SM, Altfeld M.

Front Immunol. 2017 Sep 28;8:1224. doi: 10.3389/fimmu.2017.01224. eCollection 2017. Review.

19.

Saporin-conjugated tetramers identify efficacious anti-HIV CD8+ T-cell specificities.

Leitman EM, Palmer CD, Buus S, Chen F, Riddell L, Sims S, Klenerman P, Sáez-Cirión A, Walker BD, Hess PR, Altfeld M, Matthews PC, Goulder PJR.

PLoS One. 2017 Oct 11;12(10):e0184496. doi: 10.1371/journal.pone.0184496. eCollection 2017.

20.

Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV.

Rechtien A, Richert L, Lorenzo H, Martrus G, Hejblum B, Dahlke C, Kasonta R, Zinser M, Stubbe H, Matschl U, Lohse A, Krähling V, Eickmann M, Becker S; VEBCON Consortium, Thiébaut R, Altfeld M, Addo MM.

Cell Rep. 2017 Aug 29;20(9):2251-2261. doi: 10.1016/j.celrep.2017.08.023.

21.

Reduced Expression of Siglec-7, NKG2A, and CD57 on Terminally Differentiated CD56-CD16+ Natural Killer Cell Subset Is Associated with Natural Killer Cell Dysfunction in Chronic HIV-1 Clade C Infection.

Zulu MZ, Naidoo KK, Mncube Z, Jaggernath M, Goulder PJR, Ndung'u T, Altfeld M, Thobakgale CF.

AIDS Res Hum Retroviruses. 2017 Dec;33(12):1205-1213. doi: 10.1089/AID.2017.0095. Epub 2017 Sep 21.

PMID:
28810810
22.

Proliferative capacity exhibited by human liver-resident CD49a+CD25+ NK cells.

Martrus G, Kautz T, Lunemann S, Richert L, Glau L, Salzberger W, Goebels H, Langeneckert A, Hess L, Poch T, Schramm C, Oldhafer KJ, Koch M, Tolosa E, Nashan B, Altfeld M.

PLoS One. 2017 Aug 9;12(8):e0182532. doi: 10.1371/journal.pone.0182532. eCollection 2017.

23.

Hobit expression by a subset of human liver-resident CD56bright Natural Killer cells.

Lunemann S, Martrus G, Goebels H, Kautz T, Langeneckert A, Salzberger W, Koch M, J Bunders M, Nashan B, van Gisbergen KPJM, Altfeld M.

Sci Rep. 2017 Jul 27;7(1):6676. doi: 10.1038/s41598-017-06011-7.

24.

HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells.

Körner C, Simoneau CR, Schommers P, Granoff M, Ziegler M, Hölzemer A, Lunemann S, Chukwukelu J, Corleis B, Naranbhai V, Kwon DS, Scully EP, Jost S, Kirchhoff F, Carrington M, Altfeld M.

Cell Host Microbe. 2017 Jul 12;22(1):111-119.e4. doi: 10.1016/j.chom.2017.06.008.

25.

Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.

Dulberger CL, McMurtrey CP, Hölzemer A, Neu KE, Liu V, Steinbach AM, Garcia-Beltran WF, Sulak M, Jabri B, Lynch VJ, Altfeld M, Hildebrand WH, Adams EJ.

Immunity. 2017 Jun 20;46(6):1018-1029.e7. doi: 10.1016/j.immuni.2017.06.002.

26.

Peptide-specific engagement of the activating NK cell receptor KIR2DS1.

Chapel A, Garcia-Beltran WF, Hölzemer A, Ziegler M, Lunemann S, Martrus G, Altfeld M.

Sci Rep. 2017 May 25;7(1):2414. doi: 10.1038/s41598-017-02449-x.

27.

Hepatitis C virus drives increased type I interferon-associated impairments associated with fibrosis severity in antiretroviral treatment-treated HIV-1-hepatitis C virus-coinfected individuals.

Griesbeck M, Valantin MA, Lacombe K, Samri-Hassimi A, Bottero J, Blanc C, Sbihi Z, Zoorob R, Katlama C, Guiguet M, Altfeld M, Autran B; HepACT-VIH study group.

AIDS. 2017 Jun 1;31(9):1223-1234. doi: 10.1097/QAD.0000000000001455.

PMID:
28492391
28.

TLR7-mediated activation of XBP1 correlates with the IFNα production in humans.

Beisel C, Ziegler S, Martrus Zapater G, Chapel A, Griesbeck M, Hildebrandt H, Lohse AW, Altfeld M.

Cytokine. 2017 Jun;94:55-58. doi: 10.1016/j.cyto.2017.04.006. Epub 2017 Apr 10.

PMID:
28408069
29.

Early type I Interferon response induces upregulation of human β-defensin 1 during acute HIV-1 infection.

Corleis B, Lisanti AC, Körner C, Schiff AE, Rosenberg ES, Allen TM, Altfeld M, Kwon DS.

PLoS One. 2017 Mar 2;12(3):e0173161. doi: 10.1371/journal.pone.0173161. eCollection 2017.

30.

Acute HIV-1 infection is associated with increased plasma levels of heme oxygenase-1 and presence of heme oxygenase-1-specific regulatory T cells.

Angin M, Fathi A, King M, Ledoux MB, Piechocka-Trocha A, Altfeld M, Addo MM.

AIDS. 2017 Mar 13;31(5):635-641. doi: 10.1097/QAD.0000000000001390.

PMID:
28060008
31.

Brief Report: Increased Frequency of CD39+ CD56bright Natural Killer Cells in HIV-1 Infection Correlates With Immune Activation and Disease Progression.

Dierks P, Wroblewski R, Eberhard JM, Martrus G, Degen O, Hertling S, Schmiedel S, Lunemann S, Hüfner A, Lohse AW, Altfeld M, van Lunzen J, Schulze Zur Wiesch J.

J Acquir Immune Defic Syndr. 2017 Apr 1;74(4):467-472. doi: 10.1097/QAI.0000000000001266.

PMID:
27930600
32.

Human pDCs display sex-specific differences in type I interferon subtypes and interferon α/β receptor expression.

Ziegler SM, Beisel C, Sutter K, Griesbeck M, Hildebrandt H, Hagen SH, Dittmer U, Altfeld M.

Eur J Immunol. 2017 Feb;47(2):251-256. doi: 10.1002/eji.201646725. Epub 2017 Jan 3.

33.

Comprehensive Characterization of Cellular Immune Responses Following Ebola Virus Infection.

Dahlke C, Lunemann S, Kasonta R, Kreuels B, Schmiedel S, Ly ML, Fehling SK, Strecker T, Becker S, Altfeld M, Sow A, Lohse AW, Muñoz-Fontela C, Addo MM.

J Infect Dis. 2017 Jan 15;215(2):287-292. doi: 10.1093/infdis/jiw508.

PMID:
27799354
34.

Interleukin 1-Beta (IL-1β) Production by Innate Cells Following TLR Stimulation Correlates With TB Recurrence in ART-Treated HIV-Infected Patients.

Thobakgale C, Naidoo K, McKinnon LR, Werner L, Samsunder N, Karim SA, Ndungʼu T, Altfeld M, Naidoo K.

J Acquir Immune Defic Syndr. 2017 Feb 1;74(2):213-220. doi: 10.1097/QAI.0000000000001181.

35.

Erratum to: Impact of HIV-1 infection on the feto-maternal crosstalk and consequences for pregnancy outcome and infant health.

Altfeld M, Bunders MJ.

Semin Immunopathol. 2016 Nov;38(6):783-784. No abstract available.

PMID:
27538413
36.

HLA-C levels impact natural killer cell subset distribution and function.

Sips M, Liu Q, Draghi M, Ghebremichael M, Berger CT, Suscovich TJ, Sun Y, Walker BD, Carrington M, Altfeld M, Brouckaert P, De Jager PL, Alter G.

Hum Immunol. 2016 Dec;77(12):1147-1153. doi: 10.1016/j.humimm.2016.08.004. Epub 2016 Aug 10.

PMID:
27521484
37.
38.

Kinetics of HIV-1 Latency Reversal Quantified on the Single-Cell Level Using a Novel Flow-Based Technique.

Martrus G, Niehrs A, Cornelis R, Rechtien A, García-Beltran W, Lütgehetmann M, Hoffmann C, Altfeld M.

J Virol. 2016 Sep 29;90(20):9018-28. doi: 10.1128/JVI.01448-16. Print 2016 Oct 15.

39.

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.

Garcia-Beltran WF, Hölzemer A, Martrus G, Chung AW, Pacheco Y, Simoneau CR, Rucevic M, Lamothe-Molina PA, Pertel T, Kim TE, Dugan H, Alter G, Dechanet-Merville J, Jost S, Carrington M, Altfeld M.

Nat Immunol. 2016 Sep;17(9):1067-74. doi: 10.1038/ni.3513. Epub 2016 Jul 25.

40.

Impact of HIV-1 infection on the feto-maternal crosstalk and consequences for pregnancy outcome and infant health.

Altfeld M, Bunders MJ.

Semin Immunopathol. 2016 Nov;38(6):727-738. Epub 2016 Jul 8. Review. Erratum in: Semin Immunopathol. 2016 Nov;38(6):783-784.

PMID:
27392971
41.

Sex and gender differences in HIV-1 infection.

Griesbeck M, Scully E, Altfeld M.

Clin Sci (Lond). 2016 Aug 1;130(16):1435-51. doi: 10.1042/CS20160112. Review.

PMID:
27389589
42.

Changes in HIV-1 Capsid Stability Induced by Common Cytotoxic-T-Lymphocyte-Driven Viral Sequence Mutations.

Schommers P, Martrus G, Matschl U, Sirignano M, Lütgehetmann M, Richert L, Hope TJ, Fätkenheuer G, Altfeld M.

J Virol. 2016 Jul 27;90(16):7579-7586. doi: 10.1128/JVI.00867-16. Print 2016 Aug 15.

43.

Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus.

Tully DC, Ogilvie CB, Batorsky RE, Bean DJ, Power KA, Ghebremichael M, Bedard HE, Gladden AD, Seese AM, Amero MA, Lane K, McGrath G, Bazner SB, Tinsley J, Lennon NJ, Henn MR, Brumme ZL, Norris PJ, Rosenberg ES, Mayer KH, Jessen H, Kosakovsky Pond SL, Walker BD, Altfeld M, Carlson JM, Allen TM.

PLoS Pathog. 2016 May 10;12(5):e1005619. doi: 10.1371/journal.ppat.1005619. eCollection 2016 May.

44.

Innate immune reconstitution with suppression of HIV-1.

Scully EP, Lockhart A, Garcia-Beltran W, Palmer CD, Musante C, Rosenberg E, Allen TM, Chang JJ, Bosch RJ, Altfeld M.

JCI Insight. 2016 Mar 17;1(3):e85433.

45.

Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel.

Archary D, Seaton KE, Passmore JS, Werner L, Deal A, Dunphy LJ, Arnold KB, Yates NL, Lauffenburger DA, Bergin P, Liebenberg LJ, Samsunder N, Mureithi MW, Altfeld M, Garrett N, Abdool Karim Q, Abdool Karim SS, Morris L, Tomaras GD.

Mucosal Immunol. 2016 May;9(3):834. doi: 10.1038/mi.2016.21. No abstract available.

PMID:
27116933
46.

Assessment of the antiviral capacity of primary natural killer cells by optimized in vitro quantification of HIV-1 replication.

He X, Simoneau CR, Granoff ME, Lunemann S, Dugast AS, Shao Y, Altfeld M, Körner C.

J Immunol Methods. 2016 Jul;434:53-60. doi: 10.1016/j.jim.2016.04.007. Epub 2016 Apr 16.

47.

Sequence variations in HCV core-derived epitopes alter binding of KIR2DL3 to HLA-C∗03:04 and modulate NK cell function.

Lunemann S, Martrus G, Hölzemer A, Chapel A, Ziegler M, Körner C, Garcia Beltran W, Carrington M, Wedemeyer H, Altfeld M.

J Hepatol. 2016 Aug;65(2):252-8. doi: 10.1016/j.jhep.2016.03.016. Epub 2016 Apr 4.

48.

Immunological strategies to target HIV persistence.

Martrus G, Altfeld M.

Curr Opin HIV AIDS. 2016 Jul;11(4):402-8. doi: 10.1097/COH.0000000000000289. Review.

PMID:
27054281
49.

Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16.

Gunn B, Schneider J, Shansab M, Bastian AR, Fahrbach K, Smith A 4th, Mahan A, Karim M, Licht A, Zvonar I, Tedesco J, Anderson M, Chapel A, Suscovich T, Malaspina D, Streeck H, Walker BD, Kim A, Lauer G, Altfeld M, Pillai S, Szleifer I, Kelleher NL, Kiser PF, Hope TJ, Alter G.

Mucosal Immunol. 2016 Nov;9(6):1549-1558. doi: 10.1038/mi.2016.8. Epub 2016 Mar 9.

50.

Sex differences in HIV-1-mediated immunopathology.

Ziegler S, Altfeld M.

Curr Opin HIV AIDS. 2016 Mar;11(2):209-15. doi: 10.1097/COH.0000000000000237. Review.

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