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Items: 1 to 50 of 82

1.

Methotrexate-associated toxicity in children with Down syndrome and acute lymphoblastic leukemia during consolidation therapy with high dose methotrexate according to ALL-BFM treatment regimen.

Kroll M, Kaupat-Bleckmann K, Möricke A, Alten J, Schewe DM, Stanulla M, Zimmermann M, Schrappe M, Cario G.

Haematologica. 2019 Aug 1. pii: haematol.2019.224774. doi: 10.3324/haematol.2019.224774. [Epub ahead of print]

2.

Aspiration After Congenital Heart Surgery.

Raulston JEB, Smood B, Moellinger A, Heinemann A, Smith N, Borasino S, Law MA, Alten JA.

Pediatr Cardiol. 2019 Aug;40(6):1296-1303. doi: 10.1007/s00246-019-02153-9. Epub 2019 Jul 24.

PMID:
31342114
3.

TP53, ETV6 and RUNX1 germline variants in a case series of patients developing secondary neoplasms after treatment for childhood acute lymphoblastic leukemia.

Junk SV, Klein N, Schreek S, Zimmermann M, Möricke A, Bleckmann K, Alten J, Dagdan E, Cario G, Kratz CP, Schrappe M, Stanulla M.

Haematologica. 2019 Jul 9. pii: haematol.2018.205849. doi: 10.3324/haematol.2018.205849. [Epub ahead of print]

4.

How small can you go? A 2.5-kg infant with pulmonary atresia and coronary atresia bridged to cardiac transplantation with a paracorporeal-continuous flow ventricular assist device.

Villa CR, Lorts A, Riggs KW, Alten J, Morales DL.

J Thorac Cardiovasc Surg. 2019 Aug;158(2):e67-e69. doi: 10.1016/j.jtcvs.2018.09.027. Epub 2018 Oct 5. No abstract available.

PMID:
31196758
5.

Perioperative serum albumin and its influence on clinical outcomes in neonates and infants undergoing cardiac surgery with cardiopulmonary bypass: a multi-centre retrospective study.

Henry BM, Borasino S, Ortmann L, Figueroa M, Rahman AKMF, Hock KM, Briceno-Medina M, Alten JA.

Cardiol Young. 2019 Jun;29(6):761-767. doi: 10.1017/S1047951119000738. Epub 2019 Jun 4.

PMID:
31159896
6.

Neonatal and Paediatric Heart and Renal Outcomes Network: design of a multi-centre retrospective cohort study.

Gist KM, Blinder JJ, Bailly D, Borasino S, Askenazi DJ, Cooper DS, Krawczeski CD, Gaies M, Morales DLS, Hock KM, Alten J.

Cardiol Young. 2019 Apr;29(4):511-518. doi: 10.1017/S1047951119000210.

PMID:
31107196
7.

Developmental Pharmacokinetics and Age-Appropriate Dosing Design of Milrinone in Neonates and Infants with Acute Kidney Injury Following Cardiac Surgery.

Mizuno T, Gist KM, Gao Z, Wempe MF, Alten J, Cooper DS, Goldstein SL, Vinks AA.

Clin Pharmacokinet. 2019 Jun;58(6):793-803. doi: 10.1007/s40262-018-0729-3.

PMID:
30607889
8.

Impact of Hemolysis on Acute Kidney Injury and Mortality in Children Supported with Cardiac Extracorporeal Membrane Oxygenation.

Borasino S, Kalra Y, Elam AR, Carlisle O'Meara L, Timpa JG, Goldberg KG, Collins Gaddis JL, Alten JA.

J Extra Corpor Technol. 2018 Dec;50(4):217-224.

9.

A Novel Model Demonstrates Variation in Risk-Adjusted Mortality Across Pediatric Cardiac ICUs After Surgery.

Tabbutt S, Schuette J, Zhang W, Alten J, Donohue J, Gaynor JW, Ghanayem N, Jacobs J, Pasquali SK, Thiagarajan R, Dimick JB, Banerjee M, Cooper D, Gaies M.

Pediatr Crit Care Med. 2019 Feb;20(2):136-142. doi: 10.1097/PCC.0000000000001776.

PMID:
30489488
10.

Positive Airway Pressure Versus High-Flow Nasal Cannula for Prevention of Extubation Failure in Infants After Congenital Heart Surgery.

Richter RP, Alten JA, King RW, Gans AD, Rahman AF, Kalra Y, Borasino S.

Pediatr Crit Care Med. 2019 Feb;20(2):149-157. doi: 10.1097/PCC.0000000000001783.

PMID:
30407954
11.

Variation in Adjusted Mortality for Medical Admissions to Pediatric Cardiac ICUs.

Gaies M, Ghanayem NS, Alten JA, Costello JM, Lasa JJ, Chanani NK, Shin AY, Retzloff L, Zhang W, Pasquali SK, Banerjee M, Tabbutt S.

Pediatr Crit Care Med. 2019 Feb;20(2):143-148. doi: 10.1097/PCC.0000000000001751.

PMID:
30371635
12.

Successful Angiojet® aortic thrombectomy of extracorporeal membrane oxygenation-related thrombus in a newborn.

Gutierrez ME, Alten JA, Law MA.

Ann Pediatr Cardiol. 2018 Sep-Dec;11(3):300-303. doi: 10.4103/apc.APC_26_18.

13.

Acute kidney injury after out of hospital pediatric cardiac arrest.

Cornell TT, Selewski DT, Alten JA, Askenazi D, Fitzgerald JC, Topjian A, Holubkov R, Page K, Slomine BS, Christensen JR, Dean JM, Moler FW.

Resuscitation. 2018 Oct;131:63-68. doi: 10.1016/j.resuscitation.2018.07.362. Epub 2018 Jul 31.

PMID:
30075198
14.

Nutrition Considerations in the Pediatric Cardiac Intensive Care Unit Patient.

Justice L, Buckley JR, Floh A, Horsley M, Alten J, Anand V, Schwartz SM.

World J Pediatr Congenit Heart Surg. 2018 May;9(3):333-343. doi: 10.1177/2150135118765881. Review.

PMID:
29692230
15.

Early postoperative measurement of fibroblast growth factor 23 predicts severe acute kidney injury in infants after cardiac surgery
.

Volovelsky O, Gist KM, Terrell TC, Bennett MR, Cooper DS, Alten JA, Goldstein SL.

Clin Nephrol. 2018 Sep;90(3):165-171. doi: 10.5414/CN109359.

16.

Furosemide Response Predicts Acute Kidney Injury After Cardiac Surgery in Infants and Neonates.

Borasino S, Wall KM, Crawford JH, Hock KM, Cleveland DC, Rahman F, Martin KD, Alten JA.

Pediatr Crit Care Med. 2018 Apr;19(4):310-317. doi: 10.1097/PCC.0000000000001478.

PMID:
29620706
17.

Acute Kidney Injury Biomarkers Predict an Increase in Serum Milrinone Concentration Earlier Than Serum Creatinine-Defined Acute Kidney Injury in Infants After Cardiac Surgery.

Gist KM, Cooper DS, Wrona J, Faubel S, Altmann C, Gao Z, Marino BS, Alten J, Hock KM, Mizuno T, Vinks AA, Joy MS, Wempe MF, Bennett MR, Goldstein SL.

Ther Drug Monit. 2018 Apr;40(2):186-194. doi: 10.1097/FTD.0000000000000496.

18.

Correction to: Routine Sildenafil Does Not Improve Clinical Outcomes After Fontan Operation.

Collins JLG, Law MA, Borasino S, Erwin WC, Cleveland DC, Alten JA.

Pediatr Cardiol. 2018 Mar;39(3):644-645. doi: 10.1007/s00246-018-1816-9.

PMID:
29372280
19.

The Epidemiology of Healthcare-associated Infections in Pediatric Cardiac Intensive Care Units.

Alten JA, Rahman AKMF, Zaccagni HJ, Shin A, Cooper DS, Blinder JJ, Retzloff L, Aban IB, Graham EM, Zampi J, Domnina Y, Gaies MG.

Pediatr Infect Dis J. 2018 Aug;37(8):768-772. doi: 10.1097/INF.0000000000001884.

20.

"Mouse-MRD" in central nervous system acute lymphoblastic leukaemia: assessing bone marrow minimal residual disease using a xenograft model - from bedside to the bench and back again.

Alten J, Claviez A, Vieth S, Cario G, Schewe DM.

Br J Haematol. 2018 Nov;183(4):686-688. doi: 10.1111/bjh.15024. Epub 2017 Nov 28. No abstract available.

PMID:
29193025
21.

Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies.

Cazzaniga G, De Lorenzo P, Alten J, Röttgers S, Hancock J, Saha V, Castor A, Madsen HO, Gandemer V, Cavé H, Leoni V, Köhler R, Ferrari GM, Bleckmann K, Pieters R, van der Velden V, Stary J, Zuna J, Escherich G, Stadt UZ, Aricò M, Conter V, Schrappe M, Valsecchi MG, Biondi A.

Haematologica. 2018 Jan;103(1):107-115. doi: 10.3324/haematol.2017.176917. Epub 2017 Oct 27.

22.

Routine Sildenafil Does Not Improve Clinical Outcomes After Fontan Operation.

Collins JLG, Law MA, Borasino S, Erwin WC, Cleveland DC, Alten JA.

Pediatr Cardiol. 2017 Dec;38(8):1703-1708. doi: 10.1007/s00246-017-1716-4. Epub 2017 Sep 7. Erratum in: Pediatr Cardiol. 2018 Jan 25;:.

PMID:
28884212
23.

Epidemiology of Noninvasive Ventilation in Pediatric Cardiac ICUs.

Romans RA, Schwartz SM, Costello JM, Chanani NK, Prodhan P, Gazit AZ, Smith AH, Cooper DS, Alten J, Mistry KP, Zhang W, Donohue JE, Gaies M.

Pediatr Crit Care Med. 2017 Oct;18(10):949-957. doi: 10.1097/PCC.0000000000001282.

24.

Epidemiology and Outcomes of Cardiac Arrest in Pediatric Cardiac ICUs.

Alten JA, Klugman D, Raymond TT, Cooper DS, Donohue JE, Zhang W, Pasquali SK, Gaies MG.

Pediatr Crit Care Med. 2017 Oct;18(10):935-943. doi: 10.1097/PCC.0000000000001273.

25.

The MLL recombinome of acute leukemias in 2017.

Meyer C, Burmeister T, Gröger D, Tsaur G, Fechina L, Renneville A, Sutton R, Venn NC, Emerenciano M, Pombo-de-Oliveira MS, Barbieri Blunck C, Almeida Lopes B, Zuna J, Trka J, Ballerini P, Lapillonne H, De Braekeleer M, Cazzaniga G, Corral Abascal L, van der Velden VHJ, Delabesse E, Park TS, Oh SH, Silva MLM, Lund-Aho T, Juvonen V, Moore AS, Heidenreich O, Vormoor J, Zerkalenkova E, Olshanskaya Y, Bueno C, Menendez P, Teigler-Schlegel A, Zur Stadt U, Lentes J, Göhring G, Kustanovich A, Aleinikova O, Schäfer BW, Kubetzko S, Madsen HO, Gruhn B, Duarte X, Gameiro P, Lippert E, Bidet A, Cayuela JM, Clappier E, Alonso CN, Zwaan CM, van den Heuvel-Eibrink MM, Izraeli S, Trakhtenbrot L, Archer P, Hancock J, Möricke A, Alten J, Schrappe M, Stanulla M, Strehl S, Attarbaschi A, Dworzak M, Haas OA, Panzer-Grümayer R, Sedék L, Szczepański T, Caye A, Suarez L, Cavé H, Marschalek R.

Leukemia. 2018 Feb;32(2):273-284. doi: 10.1038/leu.2017.213. Epub 2017 Jul 13.

26.

An Fc-engineered CD19 antibody eradicates MRD in patient-derived MLL-rearranged acute lymphoblastic leukemia xenografts.

Schewe DM, Alsadeq A, Sattler C, Lenk L, Vogiatzi F, Cario G, Vieth S, Valerius T, Rosskopf S, Meyersieck F, Alten J, Schrappe M, Gramatzki M, Peipp M, Kellner C.

Blood. 2017 Sep 28;130(13):1543-1552. doi: 10.1182/blood-2017-01-764316. Epub 2017 Jul 11.

27.

The authors reply.

Rhodes LA, Borasino S, Alten JA.

Pediatr Crit Care Med. 2017 Jun;18(6):605-606. doi: 10.1097/PCC.0000000000001160. No abstract available.

PMID:
28574914
28.

Impact of contrast exposure from computed tomography angiography on acute kidney injury after neonatal cardiopulmonary bypass surgery.

Carlo WF, Clark ST, Borasino S, Alten JA.

Congenit Heart Dis. 2017 Jul;12(4):540-545. doi: 10.1111/chd.12482. Epub 2017 May 30.

PMID:
28557332
29.

Clinical epidemiology and centre variation in chylothorax rates after cardiac surgery in children: a report from the Pediatric Cardiac Critical Care Consortium.

Buckley JR, Graham EM, Gaies M, Alten JA, Cooper DS, Costello JM, Domnina Y, Klugman D, Pasquali SK, Donohue JE, Zhang W, Scheurer MA.

Cardiol Young. 2017 May 29:1-8. doi: 10.1017/S104795111700097X. [Epub ahead of print]

PMID:
28552079
30.

Kinetics of the cell cycle arrest biomarkers (TIMP-2*IGFBP-7) for prediction of acute kidney injury in infants after cardiac surgery.

Gist KM, Goldstein SL, Wrona J, Alten JA, Basu RK, Cooper DS, Soranno DE, Duplantis J, Altmann C, Gao Z, Faubel S.

Pediatr Nephrol. 2017 Sep;32(9):1611-1619. doi: 10.1007/s00467-017-3655-y. Epub 2017 Apr 5.

PMID:
28382566
31.

Molecular characterization of acute lymphoblastic leukemia with high CRLF2 gene expression in childhood.

Schmäh J, Fedders B, Panzer-Grümayer R, Fischer S, Zimmermann M, Dagdan E, Bens S, Schewe D, Moericke A, Alten J, Bleckmann K, Siebert R, Schrappe M, Stanulla M, Cario G.

Pediatr Blood Cancer. 2017 Oct;64(10). doi: 10.1002/pbc.26539. Epub 2017 Apr 1.

PMID:
28371317
32.

Central Venous to Arterial CO2 Difference After Cardiac Surgery in Infants and Neonates.

Rhodes LA, Erwin WC, Borasino S, Cleveland DC, Alten JA.

Pediatr Crit Care Med. 2017 Mar;18(3):228-233. doi: 10.1097/PCC.0000000000001085.

33.

Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children.

Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Browning B, Pemberton VL, Page K, Gildea MR, Scholefield BR, Shankaran S, Hutchison JS, Berger JT, Ofori-Amanfo G, Newth CJ, Topjian A, Bennett KS, Koch JD, Pham N, Chanani NK, Pineda JA, Harrison R, Dalton HJ, Alten J, Schleien CL, Goodman DM, Zimmerman JJ, Bhalala US, Schwarz AJ, Porter MB, Shah S, Fink EL, McQuillen P, Wu T, Skellett S, Thomas NJ, Nowak JE, Baines PB, Pappachan J, Mathur M, Lloyd E, van der Jagt EW, Dobyns EL, Meyer MT, Sanders RC Jr, Clark AE, Dean JM; THAPCA Trial Investigators.

N Engl J Med. 2017 Jan 26;376(4):318-329. doi: 10.1056/NEJMoa1610493. Epub 2017 Jan 24.

34.

Defining Low Cardiac Output Syndrome: An Ode to Justice Potter Stewart.

Alten JA, Gaies M.

Pediatr Crit Care Med. 2017 Jan;18(1):85-87. doi: 10.1097/PCC.0000000000000989. No abstract available.

PMID:
28060156
35.

DNA methylation profiling of pediatric B-cell lymphoblastic leukemia with KMT2A rearrangement identifies hypomethylation at enhancer sites.

Bergmann AK, Castellano G, Alten J, Ammerpohl O, Kolarova J, Nordlund J, Martin-Subero JI, Schrappe M, Siebert R.

Pediatr Blood Cancer. 2017 Mar;64(3). doi: 10.1002/pbc.26251. Epub 2016 Oct 27.

PMID:
27786413
36.

Adrenal insufficiency in neonates after cardiac surgery with cardiopulmonary bypass.

Crawford JH, Hull MS, Borasino S, Steenwyk BL, Hock KM, Wall K, Alten JA.

Paediatr Anaesth. 2017 Jan;27(1):77-84. doi: 10.1111/pan.13013. Epub 2016 Oct 25.

PMID:
27779350
37.

Systemic thrombolysis with recombinant tissue plasminogen activator for acute life-threatening Blalock-Taussig shunt obstruction.

Diaz F, Sasser WC, Law MA, Alten JA.

Indian J Crit Care Med. 2016 Jul;20(7):425-7. doi: 10.4103/0972-5229.186248.

38.

Distal Superficial Femoral Vein Cannulation for Peripherally Inserted Central Catheter Placement in Infants with Cardiac Disease.

Richter RP, Law MA, Borasino S, Surd JA, Alten JA.

Congenit Heart Dis. 2016 Dec;11(6):733-740. doi: 10.1111/chd.12398. Epub 2016 Jul 20.

PMID:
27436222
39.

Novel, Long-axis In-plane Ultrasound-Guided Pericardiocentesis for Postoperative Pericardial Effusion Drainage.

Law MA, Borasino S, Kalra Y, Alten JA.

Pediatr Cardiol. 2016 Oct;37(7):1328-33. doi: 10.1007/s00246-016-1438-z. Epub 2016 Jul 15.

PMID:
27421844
40.

Decreasing IV Potassium in Pediatric Cardiac Intensive Care: Quality Improvement Project.

Rhodes LA, Wall KM, Abernathy SL, Moellinger AB, Borasino S, Alten JA.

Pediatr Crit Care Med. 2016 Aug;17(8):772-8. doi: 10.1097/PCC.0000000000000849.

PMID:
27362851
41.

Early Postoperative Albumin Administration Contributes to Morbidity After the Fontan Operation.

Zaccagni HJ, Alten JA, Cleveland DC, Tyler Argent R, Law MA, Bryant AS, Borasino S.

Pediatr Cardiol. 2016 Oct;37(7):1278-83. doi: 10.1007/s00246-016-1429-0. Epub 2016 Jun 9.

PMID:
27278633
42.

The authors reply.

Alten JA, Borasino S, Kim T.

Pediatr Crit Care Med. 2016 May;17(5):476. doi: 10.1097/PCC.0000000000000680. No abstract available.

PMID:
27144702
43.

Implementation of a Multidisciplinary Bleeding and Transfusion Protocol Significantly Decreases Perioperative Blood Product Utilization and Improves Some Bleeding Outcomes.

Timpa JG, O'Meara LC, Goldberg KG, Phillips JP, Crawford JH, Jackson KW, Alten JA.

J Extra Corpor Technol. 2016 Mar;48(1):11-8.

44.

Perioperative feeding management of neonates with CHD: analysis of the Pediatric Cardiac Critical Care Consortium (PC4) registry.

Alten JA, Rhodes LA, Tabbutt S, Cooper DS, Graham EM, Ghanayem N, Marino BS, Figueroa MI, Chanani NK, Jacobs JP, Donohue JE, Yu S, Gaies M.

Cardiol Young. 2015 Dec;25(8):1593-601. doi: 10.1017/S1047951115002474.

PMID:
26675610
45.

Immunologic and Infectious Diseases in Pediatric Cardiac Critical Care: Proceedings of the 10th International Pediatric Cardiac Intensive Care Society Conference.

Axelrod DM, Alten JA, Berger JT, Hall MW, Thiagarajan R, Bronicki RA.

World J Pediatr Congenit Heart Surg. 2015 Oct;6(4):575-87. doi: 10.1177/2150135115598211. Review.

PMID:
26467872
46.

Data integrity of the Pediatric Cardiac Critical Care Consortium (PC4) clinical registry.

Gaies M, Donohue JE, Willis GM, Kennedy AT, Butcher J, Scheurer MA, Alten JA, William Gaynor J, Schuette JJ, Cooper DS, Jacobs JP, Pasquali SK, Tabbutt S.

Cardiol Young. 2016 Aug;26(6):1090-6. doi: 10.1017/S1047951115001833. Epub 2015 Sep 11.

47.

Clinical Epidemiology of Extubation Failure in the Pediatric Cardiac ICU: A Report From the Pediatric Cardiac Critical Care Consortium.

Gaies M, Tabbutt S, Schwartz SM, Bird GL, Alten JA, Shekerdemian LS, Klugman D, Thiagarajan RR, Gaynor JW, Jacobs JP, Nicolson SC, Donohue JE, Yu S, Pasquali SK, Cooper DS.

Pediatr Crit Care Med. 2015 Nov;16(9):837-45. doi: 10.1097/PCC.0000000000000498.

48.

Therapeutic hypothermia after out-of-hospital cardiac arrest in children.

Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Clark AE, Browning B, Pemberton VL, Page K, Shankaran S, Hutchison JS, Newth CJ, Bennett KS, Berger JT, Topjian A, Pineda JA, Koch JD, Schleien CL, Dalton HJ, Ofori-Amanfo G, Goodman DM, Fink EL, McQuillen P, Zimmerman JJ, Thomas NJ, van der Jagt EW, Porter MB, Meyer MT, Harrison R, Pham N, Schwarz AJ, Nowak JE, Alten J, Wheeler DS, Bhalala US, Lidsky K, Lloyd E, Mathur M, Shah S, Wu T, Theodorou AA, Sanders RC Jr, Dean JM; THAPCA Trial Investigators.

N Engl J Med. 2015 May 14;372(20):1898-908. doi: 10.1056/NEJMoa1411480. Epub 2015 Apr 25.

49.

Postoperative Hydrocortisone Infusion Reduces the Prevalence of Low Cardiac Output Syndrome After Neonatal Cardiopulmonary Bypass.

Robert SM, Borasino S, Dabal RJ, Cleveland DC, Hock KM, Alten JA.

Pediatr Crit Care Med. 2015 Sep;16(7):629-36. doi: 10.1097/PCC.0000000000000426.

PMID:
25901540
50.

Secondary histiocytic sarcoma may cause apparent persistence or recurrence of minimal residual disease in childhood acute lymphoblastic leukemia.

Alten J, Klapper W, Leuschner I, Eckert C, Beier R, Vallo E, Krause M, Claviez A, Vieth S, Bleckmann K, Möricke A, Schrappe M, Cario G.

Pediatr Blood Cancer. 2015 Sep;62(9):1656-60. doi: 10.1002/pbc.25523. Epub 2015 Apr 1. Review.

PMID:
25833113

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