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Items: 1 to 50 of 66

1.

Regulatory Mechanisms of the Mucin-Like Region on Herpes Simplex Virus during Cellular Attachment.

Delguste M, Peerboom N, Le Brun G, Trybala E, Olofsson S, Bergström T, Alsteens D, Bally M.

ACS Chem Biol. 2019 Mar 15;14(3):534-542. doi: 10.1021/acschembio.9b00064. Epub 2019 Feb 21.

PMID:
30735356
2.

Seeing and sensing single G protein-coupled receptors by atomic force microscopy.

Sapra KT, Spoerri PM, Engel A, Alsteens D, Müller DJ.

Curr Opin Cell Biol. 2019 Apr;57:25-32. doi: 10.1016/j.ceb.2018.10.006. Epub 2018 Nov 6. Review.

3.

Multivalent binding of herpesvirus to living cells is tightly regulated during infection.

Delguste M, Zeippen C, Machiels B, Mast J, Gillet L, Alsteens D.

Sci Adv. 2018 Aug 17;4(8):eaat1273. doi: 10.1126/sciadv.aat1273. eCollection 2018 Aug.

4.

A molecular mechanism for Wnt ligand-specific signaling.

Eubelen M, Bostaille N, Cabochette P, Gauquier A, Tebabi P, Dumitru AC, Koehler M, Gut P, Alsteens D, Stainier DYR, Garcia-Pino A, Vanhollebeke B.

Science. 2018 Aug 17;361(6403). pii: eaat1178. doi: 10.1126/science.aat1178. Epub 2018 Jul 19.

PMID:
30026314
5.

Probing Single Virus Binding Sites on Living Mammalian Cells Using AFM.

Delguste M, Koehler M, Alsteens D.

Methods Mol Biol. 2018;1814:483-514. doi: 10.1007/978-1-4939-8591-3_29.

PMID:
29956251
6.

High-resolution mapping and recognition of lipid domains using AFM with toxin-derivatized probes.

Dumitru AC, Conrard L, Lo Giudice C, Henriet P, Veiga-da-Cunha M, Derclaye S, Tyteca D, Alsteens D.

Chem Commun (Camb). 2018 Jun 19;54(50):6903-6906. doi: 10.1039/c8cc02201a.

PMID:
29808215
7.

Mechanical Forces Guiding Staphylococcus aureus Cellular Invasion.

Prystopiuk V, Feuillie C, Herman-Bausier P, Viela F, Alsteens D, Pietrocola G, Speziale P, Dufrêne YF.

ACS Nano. 2018 Apr 24;12(4):3609-3622. doi: 10.1021/acsnano.8b00716. Epub 2018 Apr 10.

PMID:
29633832
8.

Topography imaging of herpesvirus in native condition using atomic force microscopy.

Delguste M, Koehler M, Gillet L, Alsteens D.

Clin Microbiol Infect. 2018 Jun;24(6):610-611. doi: 10.1016/j.cmi.2018.03.018. Epub 2018 Mar 23. No abstract available.

9.

Specific Interactions Measured by AFM on Living Cells between Peroxiredoxin-5 and TLR4: Relevance for Mechanisms of Innate Immunity.

Knoops B, Becker S, Poncin MA, Glibert J, Derclaye S, Clippe A, Alsteens D.

Cell Chem Biol. 2018 May 17;25(5):550-559.e3. doi: 10.1016/j.chembiol.2018.02.006. Epub 2018 Mar 15.

10.

Force-Induced Strengthening of the Interaction between Staphylococcus aureus Clumping Factor B and Loricrin.

Vitry P, Valotteau C, Feuillie C, Bernard S, Alsteens D, Geoghegan JA, Dufrêne YF.

MBio. 2017 Dec 5;8(6). pii: e01748-17. doi: 10.1128/mBio.01748-17.

11.

Biophysics: Rapid mass changes measured in cells.

Alsteens D, Dufrêne YF.

Nature. 2017 Oct 25;550(7677):465-466. doi: 10.1038/550465a. No abstract available.

PMID:
29072270
12.

Combining confocal and atomic force microscopy to quantify single-virus binding to mammalian cell surfaces.

Newton R, Delguste M, Koehler M, Dumitru AC, Laskowski PR, Müller DJ, Alsteens D.

Nat Protoc. 2017 Nov;12(11):2275-2292. doi: 10.1038/nprot.2017.112. Epub 2017 Oct 5.

PMID:
28981124
13.

Imaging modes of atomic force microscopy for application in molecular and cell biology.

Dufrêne YF, Ando T, Garcia R, Alsteens D, Martinez-Martin D, Engel A, Gerber C, Müller DJ.

Nat Nanotechnol. 2017 Apr 6;12(4):295-307. doi: 10.1038/nnano.2017.45. Review.

PMID:
28383040
14.

Multiparametric Atomic Force Microscopy Imaging of Biomolecular and Cellular Systems.

Alsteens D, Müller DJ, Dufrêne YF.

Acc Chem Res. 2017 Apr 18;50(4):924-931. doi: 10.1021/acs.accounts.6b00638. Epub 2017 Mar 28. Review.

PMID:
28350161
15.

The biomechanical properties of an epithelial tissue determine the location of its vasculature.

Kragl M, Schubert R, Karsjens H, Otter S, Bartosinska B, Jeruschke K, Weiss J, Chen C, Alsteens D, Kuss O, Speier S, Eberhard D, Müller DJ, Lammert E.

Nat Commun. 2016 Dec 20;7:13560. doi: 10.1038/ncomms13560.

16.

Nanomechanical mapping of first binding steps of a virus to animal cells.

Alsteens D, Newton R, Schubert R, Martinez-Martin D, Delguste M, Roska B, Müller DJ.

Nat Nanotechnol. 2017 Feb;12(2):177-183. doi: 10.1038/nnano.2016.228. Epub 2016 Oct 31.

PMID:
27798607
17.

Mechanical Strength and Inhibition of the Staphylococcus aureus Collagen-Binding Protein Cna.

Herman-Bausier P, Valotteau C, Pietrocola G, Rindi S, Alsteens D, Foster TJ, Speziale P, Dufrêne YF.

MBio. 2016 Oct 25;7(5). pii: e01529-16. doi: 10.1128/mBio.01529-16.

18.

[Study of membrane receptors by atomic force microscopy].

Alsteens D.

Med Sci (Paris). 2016 May;32(5):433-5. doi: 10.1051/medsci/20163205002. Epub 2016 May 25. French. No abstract available.

19.

Identifying and quantifying two ligand-binding sites while imaging native human membrane receptors by AFM.

Pfreundschuh M, Alsteens D, Wieneke R, Zhang C, Coughlin SR, Tampé R, Kobilka BK, Müller DJ.

Nat Commun. 2015 Nov 12;6:8857. doi: 10.1038/ncomms9857.

20.

Imaging G protein-coupled receptors while quantifying their ligand-binding free-energy landscape.

Alsteens D, Pfreundschuh M, Zhang C, Spoerri PM, Coughlin SR, Kobilka BK, Müller DJ.

Nat Methods. 2015 Sep;12(9):845-851. doi: 10.1038/nmeth.3479. Epub 2015 Jul 13.

21.

Single-molecule force spectroscopy of membrane proteins from membranes freely spanning across nanoscopic pores.

Petrosyan R, Bippes CA, Walheim S, Harder D, Fotiadis D, Schimmel T, Alsteens D, Müller DJ.

Nano Lett. 2015 May 13;15(5):3624-33. doi: 10.1021/acs.nanolett.5b01223. Epub 2015 Apr 21.

PMID:
25879249
22.

Force nanoscopy of hydrophobic interactions in the fungal pathogen Candida glabrata.

El-Kirat-Chatel S, Beaussart A, Derclaye S, Alsteens D, Kucharíková S, Van Dijck P, Dufrêne YF.

ACS Nano. 2015 Feb 24;9(2):1648-55. doi: 10.1021/nn506370f. Epub 2015 Jan 26.

PMID:
25621738
23.

Toward high-throughput biomechanical phenotyping of single molecules.

Alsteens D, Tay S, Müller DJ.

Nat Methods. 2015 Jan;12(1):45-6. doi: 10.1038/nmeth.3216. No abstract available.

PMID:
25549270
24.

Atomic force and electron microscopic-based study of sarcolemmal surface of living cardiomyocytes unveils unexpected mitochondrial shift in heart failure.

Dague E, Genet G, Lachaize V, Guilbeau-Frugier C, Fauconnier J, Mias C, Payré B, Chopinet L, Alsteens D, Kasas S, Severac C, Thireau J, Heymes C, Honton B, Lacampagne A, Pathak A, Sénard JM, Galés C.

J Mol Cell Cardiol. 2014 Sep;74:162-72. doi: 10.1016/j.yjmcc.2014.05.006. Epub 2014 May 17.

PMID:
24839910
25.

Localizing chemical groups while imaging single native proteins by high-resolution atomic force microscopy.

Pfreundschuh M, Alsteens D, Hilbert M, Steinmetz MO, Müller DJ.

Nano Lett. 2014 May 14;14(5):2957-64. doi: 10.1021/nl5012905. Epub 2014 May 5.

PMID:
24766578
26.

Quantifying the forces guiding microbial cell adhesion using single-cell force spectroscopy.

Beaussart A, El-Kirat-Chatel S, Sullan RM, Alsteens D, Herman P, Derclaye S, Dufrêne YF.

Nat Protoc. 2014 May;9(5):1049-55. doi: 10.1038/nprot.2014.066. Epub 2014 Apr 10.

PMID:
24722404
27.

Multiparametric atomic force microscopy imaging of single bacteriophages extruding from living bacteria.

Alsteens D, Trabelsi H, Soumillion P, Dufrêne YF.

Nat Commun. 2013;4:2926. doi: 10.1038/ncomms3926.

PMID:
24336094
28.

Quantifying the forces driving cell-cell adhesion in a fungal pathogen.

Alsteens D, Van Dijck P, Lipke PN, Dufrêne YF.

Langmuir. 2013 Nov 5;29(44):13473-80. doi: 10.1021/la403237f. Epub 2013 Oct 23.

29.

Atomic force microscopy: a new look at pathogens.

Alsteens D, Beaussart A, El-Kirat-Chatel S, Sullan RM, Dufrêne YF.

PLoS Pathog. 2013;9(9):e1003516. doi: 10.1371/journal.ppat.1003516. Epub 2013 Sep 5. Review. No abstract available.

30.

Sequential unfolding of beta helical protein by single-molecule atomic force microscopy.

Alsteens D, Martinez N, Jamin M, Jacob-Dubuisson F.

PLoS One. 2013 Aug 29;8(8):e73572. doi: 10.1371/journal.pone.0073572. eCollection 2013.

31.

Multiparametric imaging of biological systems by force-distance curve-based AFM.

Dufrêne YF, Martínez-Martín D, Medalsy I, Alsteens D, Müller DJ.

Nat Methods. 2013 Sep;10(9):847-54. doi: 10.1038/nmeth.2602. Review.

PMID:
23985731
32.

Single-Cell Force Spectroscopy of Als-Mediated Fungal Adhesion.

Alsteens D, Beaussart A, Derclaye S, El-Kirat-Chatel S, Park HR, Lipke PN, Dufrêne YF.

Anal Methods. 2013 Aug 7;5(15):3657-3662.

33.

Unraveling the nanoscale surface properties of chitin synthase mutants of Aspergillus fumigatus and their biological implications.

Alsteens D, Aimanianda V, Hegde P, Pire S, Beau R, Bayry J, Latgé JP, Dufrêne YF.

Biophys J. 2013 Jul 16;105(2):320-7. doi: 10.1016/j.bpj.2013.05.040.

34.

Single-cell force spectroscopy of probiotic bacteria.

Beaussart A, El-Kirat-Chatel S, Herman P, Alsteens D, Mahillon J, Hols P, Dufrêne YF.

Biophys J. 2013 May 7;104(9):1886-92. doi: 10.1016/j.bpj.2013.03.046.

35.

Single-molecule analysis of the major glycopolymers of pathogenic and non-pathogenic yeast cells.

El-Kirat-Chatel S, Beaussart A, Alsteens D, Sarazin A, Jouault T, Dufrêne YF.

Nanoscale. 2013 Jun 7;5(11):4855-63. doi: 10.1039/c3nr00813d. Epub 2013 Apr 24.

PMID:
23615555
36.

Adhesion and nanomechanics of pili from the probiotic Lactobacillus rhamnosus GG.

Tripathi P, Beaussart A, Alsteens D, Dupres V, Claes I, von Ossowski I, de Vos WM, Palva A, Lebeer S, Vanderleyden J, Dufrêne YF.

ACS Nano. 2013 Apr 23;7(4):3685-97. doi: 10.1021/nn400705u. Epub 2013 Mar 26.

PMID:
23531039
37.

Nanoscale analysis of caspofungin-induced cell surface remodelling in Candida albicans.

El-Kirat-Chatel S, Beaussart A, Alsteens D, Jackson DN, Lipke PN, Dufrêne YF.

Nanoscale. 2013 Feb 7;5(3):1105-15. doi: 10.1039/c2nr33215a. Epub 2012 Dec 21.

38.

High-resolution imaging of chemical and biological sites on living cells using peak force tapping atomic force microscopy.

Alsteens D, Dupres V, Yunus S, Latgé JP, Heinisch JJ, Dufrêne YF.

Langmuir. 2012 Dec 11;28(49):16738-44. doi: 10.1021/la303891j. Epub 2012 Nov 30.

PMID:
23198968
39.

Single-molecule imaging and functional analysis of Als adhesins and mannans during Candida albicans morphogenesis.

Beaussart A, Alsteens D, El-Kirat-Chatel S, Lipke PN, Kucharíková S, Van Dijck P, Dufrêne YF.

ACS Nano. 2012 Dec 21;6(12):10950-64. doi: 10.1021/nn304505s. Epub 2012 Nov 12.

40.

Atomic force microscopy - looking at mechanosensors on the cell surface.

Heinisch JJ, Lipke PN, Beaussart A, El Kirat Chatel S, Dupres V, Alsteens D, Dufrêne YF.

J Cell Sci. 2012 Sep 15;125(Pt 18):4189-95. doi: 10.1242/jcs.106005. Epub 2012 Oct 17. Review.

41.

Chitin synthases with a myosin motor-like domain control the resistance of Aspergillus fumigatus to echinocandins.

Jiménez-Ortigosa C, Aimanianda V, Muszkieta L, Mouyna I, Alsteens D, Pire S, Beau R, Krappmann S, Beauvais A, Dufrêne YF, Roncero C, Latgé JP.

Antimicrob Agents Chemother. 2012 Dec;56(12):6121-31. doi: 10.1128/AAC.00752-12. Epub 2012 Sep 10.

42.

Unzipping a functional microbial amyloid.

Alsteens D, Ramsook CB, Lipke PN, Dufrêne YF.

ACS Nano. 2012 Sep 25;6(9):7703-11. Epub 2012 Aug 27.

43.

Microbial cells analysis by atomic force microscopy.

Alsteens D.

Methods Enzymol. 2012;506:3-17. doi: 10.1016/B978-0-12-391856-7.00025-1.

PMID:
22341216
44.

Strengthening relationships: amyloids create adhesion nanodomains in yeasts.

Lipke PN, Garcia MC, Alsteens D, Ramsook CB, Klotz SA, Dufrêne YF.

Trends Microbiol. 2012 Feb;20(2):59-65. doi: 10.1016/j.tim.2011.10.002. Epub 2011 Nov 16.

45.

A role for amyloid in cell aggregation and biofilm formation.

Garcia MC, Lee JT, Ramsook CB, Alsteens D, Dufrêne YF, Lipke PN.

PLoS One. 2011 Mar 8;6(3):e17632. doi: 10.1371/journal.pone.0017632.

46.

Frontiers in microbial nanoscopy.

Alsteens D, Dupres V, Andre G, Dufrêne YF.

Nanomedicine (Lond). 2011 Feb;6(2):395-403. doi: 10.2217/nnm.10.151. Review.

PMID:
21385140
47.

The Pseudomonas aeruginosa membranes: a target for a new amphiphilic aminoglycoside derivative?

Ouberai M, El Garch F, Bussiere A, Riou M, Alsteens D, Lins L, Baussanne I, Dufrêne YF, Brasseur R, Decout JL, Mingeot-Leclercq MP.

Biochim Biophys Acta. 2011 Jun;1808(6):1716-27. doi: 10.1016/j.bbamem.2011.01.014. Epub 2011 Feb 1.

48.

Force-induced formation and propagation of adhesion nanodomains in living fungal cells.

Alsteens D, Garcia MC, Lipke PN, Dufrêne YF.

Proc Natl Acad Sci U S A. 2010 Nov 30;107(48):20744-9. doi: 10.1073/pnas.1013893107. Epub 2010 Nov 8.

49.

Microbial nanoscopy: a closer look at microbial cell surfaces.

Dupres V, Alsteens D, Andre G, Dufrêne YF.

Trends Microbiol. 2010 Sep;18(9):397-405. doi: 10.1016/j.tim.2010.06.004. Epub 2010 Jul 12.

PMID:
20630762
50.

Measurement of the mechanical behavior of yeast membrane sensors using single-molecule atomic force microscopy.

Heinisch JJ, Dupres V, Alsteens D, Dufrêne YF.

Nat Protoc. 2010 Apr;5(4):670-7. doi: 10.1038/nprot.2010.19. Epub 2010 Mar 18.

PMID:
20360762

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