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Items: 10

1.

Inhibition of the stromal p38MAPK/MK2 pathway limits breast cancer metastases and chemotherapy-induced bone loss.

Murali B, Ren Q, Luo X, Faget DV, Wang C, Johnson RM, Gruosso T, Flanagan KC, Fu Y, Leahy KM, Alspach E, Su X, Ross MH, Burnette B, Weilbaecher KN, Park M, Mbalaviele G, Monahan J, Stewart SA.

Cancer Res. 2018 Aug 9. pii: canres.0234.2018. doi: 10.1158/0008-5472.CAN-18-0234. [Epub ahead of print]

PMID:
30093561
2.

Interferon γ and Its Important Roles in Promoting and Inhibiting Spontaneous and Therapeutic Cancer Immunity.

Alspach E, Lussier DM, Schreiber RD.

Cold Spring Harb Perspect Biol. 2018 Apr 16. pii: a028480. doi: 10.1101/cshperspect.a028480. [Epub ahead of print]

PMID:
29661791
3.

c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors.

Flanagan KC, Alspach E, Pazolli E, Parajuli S, Ren Q, Arthur LL, Tapia R, Stewart SA.

Oncotarget. 2017 Dec 5;9(1):21-36. doi: 10.18632/oncotarget.22940. eCollection 2018 Jan 2.

4.

Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.

Ruhland MK, Loza AJ, Capietto AH, Luo X, Knolhoff BL, Flanagan KC, Belt BA, Alspach E, Leahy K, Luo J, Schaffer A, Edwards JR, Longmore G, Faccio R, DeNardo DG, Stewart SA.

Nat Commun. 2016 Jun 8;7:11762. doi: 10.1038/ncomms11762.

5.

Hematopoietic Age at Onset of Triple-Negative Breast Cancer Dictates Disease Aggressiveness and Progression.

Marsh T, Wong I, Sceneay J, Barakat A, Qin Y, Sjödin A, Alspach E, Nilsson B, Stewart SA, McAllister SS.

Cancer Res. 2016 May 15;76(10):2932-43. doi: 10.1158/0008-5472.CAN-15-3332. Epub 2016 Apr 7.

7.

Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand.

Teasley DC, Parajuli S, Nguyen M, Moore HR, Alspach E, Lock YJ, Honaker Y, Saharia A, Piwnica-Worms H, Stewart SA.

J Biol Chem. 2015 Jun 12;290(24):15133-45. doi: 10.1074/jbc.M115.647388. Epub 2015 Apr 28.

8.

p38MAPK plays a crucial role in stromal-mediated tumorigenesis.

Alspach E, Flanagan KC, Luo X, Ruhland MK, Huang H, Pazolli E, Donlin MJ, Marsh T, Piwnica-Worms D, Monahan J, Novack DV, McAllister SS, Stewart SA.

Cancer Discov. 2014 Jun;4(6):716-29. doi: 10.1158/2159-8290.CD-13-0743. Epub 2014 Mar 26.

9.

Senescence and the pro-tumorigenic stroma.

Alspach E, Fu Y, Stewart SA.

Crit Rev Oncog. 2013;18(6):549-58. Review.

10.

Chromatin remodeling underlies the senescence-associated secretory phenotype of tumor stromal fibroblasts that supports cancer progression.

Pazolli E, Alspach E, Milczarek A, Prior J, Piwnica-Worms D, Stewart SA.

Cancer Res. 2012 May 1;72(9):2251-61. doi: 10.1158/0008-5472.CAN-11-3386. Epub 2012 Mar 15.

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