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Items: 29


Direct interaction of whole-inactivated influenza A and pneumococcal vaccines enhances influenza-specific immunity.

David SC, Norton T, Tyllis T, Wilson JJ, Singleton EV, Laan Z, Davies J, Hirst TR, Comerford I, McColl SR, Paton JC, Alsharifi M.

Nat Microbiol. 2019 Aug;4(8):1316-1327. doi: 10.1038/s41564-019-0443-4. Epub 2019 May 20.


Enhanced safety and immunogenicity of a pneumococcal surface antigen A mutant whole-cell inactivated pneumococcal vaccine.

David SC, Laan Z, Minhas V, Chen AY, Davies J, Hirst TR, McColl SR, Alsharifi M, Paton JC.

Immunol Cell Biol. 2019 May 3. doi: 10.1111/imcb.12257. [Epub ahead of print]


Gamma-irradiated rotavirus: A possible whole virus inactivated vaccine.

Shahrudin S, Chen C, David SC, Singleton EV, Davies J, Kirkwood CD, Hirst TR, Beard M, Alsharifi M.

PLoS One. 2018 Jun 7;13(6):e0198182. doi: 10.1371/journal.pone.0198182. eCollection 2018.


Atypical chemokine receptor 4 shapes activated B cell fate.

Kara EE, Bastow CR, McKenzie DR, Gregor CE, Fenix KA, Babb R, Norton TS, Zotos D, Rodda LB, Hermes JR, Bourne K, Gilchrist DS, Nibbs RJ, Alsharifi M, Vinuesa CG, Tarlinton DM, Brink R, Hill GR, Cyster JG, Comerford I, McColl SR.

J Exp Med. 2018 Mar 5;215(3):801-813. doi: 10.1084/jem.20171067. Epub 2018 Jan 31.


The effect of gamma-irradiation conditions on the immunogenicity of whole-inactivated Influenza A virus vaccine.

David SC, Lau J, Singleton EV, Babb R, Davies J, Hirst TR, McColl SR, Paton JC, Alsharifi M.

Vaccine. 2017 Feb 15;35(7):1071-1079. doi: 10.1016/j.vaccine.2016.12.044. Epub 2017 Jan 18.


Intracranial Injection of Dengue Virus Induces Interferon Stimulated Genes and CD8+ T Cell Infiltration by Sphingosine Kinase 1 Independent Pathways.

Al-Shujairi WH, Clarke JN, Davies LT, Alsharifi M, Pitson SM, Carr JM.

PLoS One. 2017 Jan 17;12(1):e0169814. doi: 10.1371/journal.pone.0169814. eCollection 2017.


Enhanced protective responses to a serotype-independent pneumococcal vaccine when combined with an inactivated influenza vaccine.

Babb R, Chen A, Ogunniyi AD, Hirst TR, Kara EE, McColl SR, Alsharifi M, Paton JC.

Clin Sci (Lond). 2017 Jan 1;131(2):169-180. doi: 10.1042/CS20160475. Epub 2016 Nov 24.


Preserved antiviral adaptive immunity following polyclonal antibody immunotherapy for severe murine influenza infection.

Stevens NE, Hatjopolous A, Fraser CK, Alsharifi M, Diener KR, Hayball JD.

Sci Rep. 2016 Jul 6;6:29154. doi: 10.1038/srep29154.


Intranasal vaccination with γ-irradiated Streptococcus pneumoniae whole-cell vaccine provides serotype-independent protection mediated by B-cells and innate IL-17 responses.

Babb R, Chen A, Hirst TR, Kara EE, McColl SR, Ogunniyi AD, Paton JC, Alsharifi M.

Clin Sci (Lond). 2016 May;130(9):697-710. doi: 10.1042/CS20150699. Epub 2016 Feb 1.


Vaccine-Induced Antibody Responses Prevent the Induction of Interferon Type I Responses Upon a Homotypic Live Virus Challenge.

Chan J, Babb R, David SC, McColl SR, Alsharifi M.

Scand J Immunol. 2016 Mar;83(3):165-73. doi: 10.1111/sji.12410.


Gamma-Irradiated Influenza A Virus Provides Adjuvant Activity to a Co-Administered Poorly Immunogenic SFV Vaccine in Mice.

Babb R, Chan J, Khairat JE, Furuya Y, Alsharifi M.

Front Immunol. 2014 Jun 10;5:267. doi: 10.3389/fimmu.2014.00267. eCollection 2014.


Understanding the undelaying mechanism of HA-subtyping in the level of physic-chemical characteristics of protein.

Ebrahimi M, Aghagolzadeh P, Shamabadi N, Tahmasebi A, Alsharifi M, Adelson DL, Hemmatzadeh F, Ebrahimie E.

PLoS One. 2014 May 8;9(5):e96984. doi: 10.1371/journal.pone.0096984. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e99921.


MHC class II-alpha chain knockout mice support increased viral replication that is independent of their lack of MHC class II cell surface expression and associated immune function deficiencies.

Alsharifi M, Koskinen A, Wijesundara DK, Bettadapura J, Müllbacher A.

PLoS One. 2013 Jun 28;8(6):e68458. doi: 10.1371/journal.pone.0068458. Print 2013.


Gamma-irradiated influenza virus uniquely induces IFN-I mediated lymphocyte activation independent of the TLR7/MyD88 pathway.

Furuya Y, Chan J, Wan EC, Koskinen A, Diener KR, Hayball JD, Regner M, Müllbacher A, Alsharifi M.

PLoS One. 2011;6(10):e25765. doi: 10.1371/journal.pone.0025765. Epub 2011 Oct 5.


Antigen-specific activation thresholds of CD8+ T cells are independent of IFN-I-mediated partial lymphocyte activation.

Wijesundara DK, Kumar S, Alsharifi M, Müllbacher A, Regner M.

Int Immunol. 2010 Sep;22(9):757-67. doi: 10.1093/intimm/dxq064. Epub 2010 Aug 2.


Cytotoxic T cells are the predominant players providing cross-protective immunity induced by {gamma}-irradiated influenza A viruses.

Furuya Y, Chan J, Regner M, Lobigs M, Koskinen A, Kok T, Manavis J, Li P, Müllbacher A, Alsharifi M.

J Virol. 2010 May;84(9):4212-21. doi: 10.1128/JVI.02508-09. Epub 2010 Feb 17.


Effect of inactivation method on the cross-protective immunity induced by whole 'killed' influenza A viruses and commercial vaccine preparations.

Furuya Y, Regner M, Lobigs M, Koskinen A, Müllbacher A, Alsharifi M.

J Gen Virol. 2010 Jun;91(Pt 6):1450-60. doi: 10.1099/vir.0.018168-0. Epub 2010 Feb 10.


The gamma-irradiated influenza vaccine and the prospect of producing safe vaccines in general.

Alsharifi M, Müllbacher A.

Immunol Cell Biol. 2010 Feb;88(2):103-4. doi: 10.1038/icb.2009.81. Epub 2009 Oct 27. No abstract available.


Intranasal flu vaccine protective against seasonal and H5N1 avian influenza infections.

Alsharifi M, Furuya Y, Bowden TR, Lobigs M, Koskinen A, Regner M, Trinidad L, Boyle DB, Müllbacher A.

PLoS One. 2009;4(4):e5336. doi: 10.1371/journal.pone.0005336. Epub 2009 Apr 29.


Live chimeric and inactivated Japanese encephalitis virus vaccines differ in their cross-protective values against Murray Valley encephalitis virus.

Lobigs M, Larena M, Alsharifi M, Lee E, Pavy M.

J Virol. 2009 Mar;83(6):2436-45. doi: 10.1128/JVI.02273-08. Epub 2008 Dec 24.


Restricted Semliki Forest virus replication in perforin and Fas-ligand double-deficient mice.

Alsharifi M, Lobigs M, Bettadapura J, Koskinen A, Müllbacher A.

J Gen Virol. 2008 Aug;89(Pt 8):1942-4. doi: 10.1099/vir.0.83626-0.


Interferon type I responses in primary and secondary infections.

Alsharifi M, Müllbacher A, Regner M.

Immunol Cell Biol. 2008 Mar-Apr;86(3):239-45. doi: 10.1038/sj.icb.7100159. Epub 2008 Jan 8. Review.


Increased survival after gemfibrozil treatment of severe mouse influenza.

Budd A, Alleva L, Alsharifi M, Koskinen A, Smythe V, Müllbacher A, Wood J, Clark I.

Antimicrob Agents Chemother. 2007 Aug;51(8):2965-8. Epub 2007 Jun 11.


Exhaustion of type I interferon response following an acute viral infection.

Alsharifi M, Regner M, Blanden R, Lobigs M, Lee E, Koskinen A, Müllbacher A.

J Immunol. 2006 Sep 1;177(5):3235-41.


Cytotoxic T-cell immunity as a target for influenza vaccines.

Müllbacher A, Lobigs M, Alsharifi M, Regner M.

Lancet Infect Dis. 2006 May;6(5):255-6. No abstract available.


NK cell-mediated immunopathology during an acute viral infection of the CNS.

Alsharifi M, Lobigs M, Simon MM, Kersten A, Müller K, Koskinen A, Lee E, Müllbacher A.

Eur J Immunol. 2006 Apr;36(4):887-96.


Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor.

Rosen DB, Bettadapura J, Alsharifi M, Mathew PA, Warren HS, Lanier LL.

J Immunol. 2005 Dec 15;175(12):7796-9.


Type I interferons trigger systemic, partial lymphocyte activation in response to viral infection.

Alsharifi M, Lobigs M, Regner M, Lee E, Koskinen A, Müllbacher A.

J Immunol. 2005 Oct 1;175(7):4635-40.

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