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Items: 1 to 50 of 187

1.

Preclinical Validation of a Single-Scan Rest/Stress Imaging Technique for 13N-Ammonia Positron Emission Tomography Cardiac Perfusion Studies.

Guehl NJ, Pelletier-Galarneau M, Wooten DW, Guerrero JL, Kas A, Normandin MD, Fakhri GE, Alpert NM.

Circ Cardiovasc Imaging. 2020 Jan;13(1):e009407. doi: 10.1161/CIRCIMAGING.119.009407. Epub 2020 Jan 21.

PMID:
31959009
2.

Body motion detection and correction in cardiac PET: Phantom and human studies.

Sun T, Petibon Y, Han PK, Ma C, Kim SJW, Alpert NM, El Fakhri G, Ouyang J.

Med Phys. 2019 Nov;46(11):4898-4906. doi: 10.1002/mp.13815. Epub 2019 Oct 8.

PMID:
31508827
3.

Quantitative in vivo mapping of myocardial mitochondrial membrane potential.

Alpert NM, Guehl N, Ptaszek L, Pelletier-Galarneau M, Ruskin J, Mansour MC, Wooten D, Ma C, Takahashi K, Zhou Y, Shoup TM, Normandin MD, El Fakhri G.

PLoS One. 2018 Jan 16;13(1):e0190968. doi: 10.1371/journal.pone.0190968. eCollection 2018. Erratum in: PLoS One. 2018 Feb 8;13(2):e0192876.

4.

Frontostriatal and Dopamine Markers of Individual Differences in Reinforcement Learning: A Multi-modal Investigation.

Kaiser RH, Treadway MT, Wooten DW, Kumar P, Goer F, Murray L, Beltzer M, Pechtel P, Whitton A, Cohen AL, Alpert NM, El Fakhri G, Normandin MD, Pizzagalli DA.

Cereb Cortex. 2018 Dec 1;28(12):4281-4290. doi: 10.1093/cercor/bhx281.

5.

Rapid computation of single PET scan rest-stress myocardial blood flow parametric images by table look up.

Guehl NJ, Normandin MD, Wooten DW, Rozen G, Ruskin JN, Shoup TM, Woo J, Ptaszek LM, Fakhri GE, Alpert NM.

Med Phys. 2017 Sep;44(9):4643-4651. doi: 10.1002/mp.12398. Epub 2017 Jul 18.

6.

Single-scan rest/stress imaging: validation in a porcine model with 18F-Flurpiridaz.

Guehl NJ, Normandin MD, Wooten DW, Rozen G, Sitek A, Ruskin J, Shoup TM, Ptaszek LM, El Fakhri G, Alpert NM.

Eur J Nucl Med Mol Imaging. 2017 Aug;44(9):1538-1546. doi: 10.1007/s00259-017-3684-6. Epub 2017 Apr 1.

PMID:
28365789
7.

Impact of motion and partial volume effects correction on PET myocardial perfusion imaging using simultaneous PET-MR.

Petibon Y, Guehl NJ, Reese TG, Ebrahimi B, Normandin MD, Shoup TM, Alpert NM, El Fakhri G, Ouyang J.

Phys Med Biol. 2017 Jan 21;62(2):326-343. doi: 10.1088/1361-6560/aa5087. Epub 2016 Dec 20.

8.

Validation of Bayesian analysis of compartmental kinetic models in medical imaging.

Sitek A, Li Q, El Fakhri G, Alpert NM.

Phys Med. 2016 Oct;32(10):1252-1258. doi: 10.1016/j.ejmp.2016.09.010. Epub 2016 Sep 28.

9.

National Electrical Manufacturers Association and Clinical Evaluation of a Novel Brain PET/CT Scanner.

Grogg KS, Toole T, Ouyang J, Zhu X, Normandin MD, Li Q, Johnson K, Alpert NM, El Fakhri G.

J Nucl Med. 2016 Apr;57(4):646-52. doi: 10.2967/jnumed.115.159723. Epub 2015 Dec 23.

10.

Mapping (15)O production rate for proton therapy verification.

Grogg K, Alpert NM, Zhu X, Min CH, Testa M, Winey B, Normandin MD, Shih HA, Paganetti H, Bortfeld T, El Fakhri G.

Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):453-9. doi: 10.1016/j.ijrobp.2015.01.023. Epub 2015 Mar 25.

11.

Direct reconstruction of cardiac PET kinetic parametric images using a preconditioned conjugate gradient approach.

Rakvongthai Y, Ouyang J, Guerin B, Li Q, Alpert NM, El Fakhri G.

Med Phys. 2013 Oct;40(10):102501. doi: 10.1118/1.4819821.

12.

Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI.

Sander CY, Hooker JM, Catana C, Normandin MD, Alpert NM, Knudsen GM, Vanduffel W, Rosen BR, Mandeville JB.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11169-74. doi: 10.1073/pnas.1220512110. Epub 2013 May 30.

13.

Dual-tracer PET using generalized factor analysis of dynamic sequences.

El Fakhri G, Trott CM, Sitek A, Bonab A, Alpert NM.

Mol Imaging Biol. 2013 Dec;15(6):666-74. doi: 10.1007/s11307-013-0631-1.

14.

A receptor-based model for dopamine-induced fMRI signal.

Mandeville JB, Sander CYM, Jenkins BG, Hooker JM, Catana C, Vanduffel W, Alpert NM, Rosen BR, Normandin MD.

Neuroimage. 2013 Jul 15;75:46-57. doi: 10.1016/j.neuroimage.2013.02.036. Epub 2013 Mar 1.

15.

MRI-based nonrigid motion correction in simultaneous PET/MRI.

Chun SY, Reese TG, Ouyang J, Guerin B, Catana C, Zhu X, Alpert NM, El Fakhri G.

J Nucl Med. 2012 Aug;53(8):1284-91. doi: 10.2967/jnumed.111.092353. Epub 2012 Jun 28.

16.

Parametric imaging with Bayesian priors: a validation study with (11)C-Altropane PET.

Fang YH, El Fakhri G, Becker JA, Alpert NM.

Neuroimage. 2012 May 15;61(1):131-8. doi: 10.1016/j.neuroimage.2012.03.003. Epub 2012 Mar 9.

PMID:
22425668
17.

Nonrigid PET motion compensation in the lower abdomen using simultaneous tagged-MRI and PET imaging.

Guérin B, Cho S, Chun SY, Zhu X, Alpert NM, El Fakhri G, Reese T, Catana C.

Med Phys. 2011 Jun;38(6):3025-38.

18.

Decreased regional cerebral blood flow in medial prefrontal cortex during trauma-unrelated stressful imagery in Vietnam veterans with post-traumatic stress disorder.

Gold AL, Shin LM, Orr SP, Carson MA, Rauch SL, Macklin ML, Lasko NB, Metzger LJ, Dougherty DD, Alpert NM, Fischman AJ, Pitman RK.

Psychol Med. 2011 Dec;41(12):2563-72. doi: 10.1017/S0033291711000730. Epub 2011 May 13.

PMID:
21733221
19.

Dopamine release during human emotional processing.

Badgaiyan RD, Fischman AJ, Alpert NM.

Neuroimage. 2009 Oct 1;47(4):2041-5. doi: 10.1016/j.neuroimage.2009.06.008. Epub 2009 Jun 11.

20.

A general method of Bayesian estimation for parametric imaging of the brain.

Alpert NM, Yuan F.

Neuroimage. 2009 May 1;45(4):1183-9. doi: 10.1016/j.neuroimage.2008.12.064. Epub 2009 Jan 14.

PMID:
19349233
21.

Explicit motor memory activates the striatal dopamine system.

Badgaiyan RD, Fischman AJ, Alpert NM.

Neuroreport. 2008 Mar 5;19(4):409-12. doi: 10.1097/WNR.0b013e3282f6435f.

PMID:
18287937
22.

Striatal dopamine release in sequential learning.

Badgaiyan RD, Fischman AJ, Alpert NM.

Neuroimage. 2007 Nov 15;38(3):549-56. Epub 2007 Aug 15.

23.

PET/CT imaging for treatment verification after proton therapy: a study with plastic phantoms and metallic implants.

Parodi K, Paganetti H, Cascio E, Flanz JB, Bonab AA, Alpert NM, Lohmann K, Bortfeld T.

Med Phys. 2007 Feb;34(2):419-35.

24.

A functional neuroimaging investigation of deep brain stimulation in patients with obsessive-compulsive disorder.

Rauch SL, Dougherty DD, Malone D, Rezai A, Friehs G, Fischman AJ, Alpert NM, Haber SN, Stypulkowski PH, Rise MT, Rasmussen SA, Greenberg BD.

J Neurosurg. 2006 Apr;104(4):558-65.

PMID:
16619660
25.

Decreased striatal D1 binding as measured using PET and [11C]SCH 23,390 in patients with major depression with anger attacks.

Dougherty DD, Bonab AA, Ottowitz WE, Livni E, Alpert NM, Rauch SL, Fava M, Fischman AJ.

Depress Anxiety. 2006;23(3):175-7.

PMID:
16528700
26.

Optimization of dynamic measurement of receptor kinetics by wavelet denoising.

Alpert NM, Reilhac A, Chio TC, Selesnick I.

Neuroimage. 2006 Apr 1;30(2):444-51. Epub 2005 Oct 27.

PMID:
16257238
27.

Accelerated triacylglycerol turnover kinetics in hearts of diabetic rats include evidence for compartmented lipid storage.

O'Donnell JM, Zampino M, Alpert NM, Fasano MJ, Geenen DL, Lewandowski ED.

Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E448-55. Epub 2005 Oct 18.

28.

Effects of sildenafil on myocardial blood flow in humans with ischemic heart disease.

Tawakol A, Aziz K, Migrino R, Watkowska J, Zusman R, Alpert NM, Fischman AJ, Gewirtz H.

Coron Artery Dis. 2005 Nov;16(7):443-9.

PMID:
16205453
29.

Two types of image generation: evidence from PET.

Kosslyn SM, Thompson WL, Sukel KE, Alpert NM.

Cogn Affect Behav Neurosci. 2005 Mar;5(1):41-53.

PMID:
15913007
30.

High-dose folic acid acutely improves coronary vasodilator function in patients with coronary artery disease.

Tawakol A, Migrino RQ, Aziz KS, Waitkowska J, Holmvang G, Alpert NM, Muller JE, Fischman AJ, Gewirtz H.

J Am Coll Cardiol. 2005 May 17;45(10):1580-4. Epub 2005 Apr 26.

31.

Ventromedial prefrontal cortex and amygdala dysfunction during an anger induction positron emission tomography study in patients with major depressive disorder with anger attacks.

Dougherty DD, Rauch SL, Deckersbach T, Marci C, Loh R, Shin LM, Alpert NM, Fischman AJ, Fava M.

Arch Gen Psychiatry. 2004 Aug;61(8):795-804.

PMID:
15289278
32.

Hippocampal function in posttraumatic stress disorder.

Shin LM, Shin PS, Heckers S, Krangel TS, Macklin ML, Orr SP, Lasko N, Segal E, Makris N, Richert K, Levering J, Schacter DL, Alpert NM, Fischman AJ, Pitman RK, Rauch SL.

Hippocampus. 2004;14(3):292-300.

PMID:
15132428
33.

Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSD.

Shin LM, Orr SP, Carson MA, Rauch SL, Macklin ML, Lasko NB, Peters PM, Metzger LJ, Dougherty DD, Cannistraro PA, Alpert NM, Fischman AJ, Pitman RK.

Arch Gen Psychiatry. 2004 Feb;61(2):168-76.

PMID:
14757593
34.

Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for treatment of major depression.

Dougherty DD, Weiss AP, Cosgrove GR, Alpert NM, Cassem EH, Nierenberg AA, Price BH, Mayberg HS, Fischman AJ, Rauch SL.

J Neurosurg. 2003 Dec;99(6):1010-7.

PMID:
14705729
35.

Priming of new associations: a PET study.

Badgaiyan RD, Schacter DL, Alpert NM.

Neuroreport. 2003 Dec 19;14(18):2475-9.

PMID:
14663213
36.

Striatal dopamine release during unrewarded motor task in human volunteers.

Badgaiyan RD, Fischman AJ, Alpert NM.

Neuroreport. 2003 Aug 6;14(11):1421-4.

PMID:
12960756
37.

Improved radiologic staging of lung cancer with 2-[18F]-fluoro-2-deoxy-D-glucose-positron emission tomography and computed tomography registration.

Aquino SL, Asmuth JC, Alpert NM, Halpern EF, Fischman AJ.

J Comput Assist Tomogr. 2003 Jul-Aug;27(4):479-84.

PMID:
12886128
38.

A novel method for noninvasive detection of neuromodulatory changes in specific neurotransmitter systems.

Alpert NM, Badgaiyan RD, Livni E, Fischman AJ.

Neuroimage. 2003 Jul;19(3):1049-60.

PMID:
12880831
39.

Implicit transfer of motor strategies in mental rotation.

Wraga M, Thompson WL, Alpert NM, Kosslyn SM.

Brain Cogn. 2003 Jul;52(2):135-43.

PMID:
12821095
40.
41.

Coregistration of head CT comparison studies: assessment of clinical utility.

Schellingerhout D, Lev MH, Bagga RJ, Rincon S, Berdichevsky D, Thangaraj V, Gonzalez RG, Alpert NM.

Acad Radiol. 2003 Mar;10(3):242-8.

PMID:
12643550
42.

Impaired hippocampal recruitment during normal modulation of memory performance in schizophrenia.

Weiss AP, Schacter DL, Goff DC, Rauch SL, Alpert NM, Fischman AJ, Heckers S.

Biol Psychiatry. 2003 Jan 1;53(1):48-55.

PMID:
12513944
43.

Retrieval of relational information: a role for the left inferior prefrontal cortex.

Badgaiyan RD, Schacter DL, Alpert NM.

Neuroimage. 2002 Sep;17(1):393-400.

PMID:
12482092
44.

Predictors of fluvoxamine response in contamination-related obsessive compulsive disorder: a PET symptom provocation study.

Rauch SL, Shin LM, Dougherty DD, Alpert NM, Fischman AJ, Jenike MA.

Neuropsychopharmacology. 2002 Nov;27(5):782-91.

45.

Homocysteine impairs coronary microvascular dilator function in humans.

Tawakol A, Forgione MA, Stuehlinger M, Alpert NM, Cooke JP, Loscalzo J, Fischman AJ, Creager MA, Gewirtz H.

J Am Coll Cardiol. 2002 Sep 18;40(6):1051-58.

46.

Hippocampal and brain stem activation during word retrieval after repeated and semantic encoding.

Heckers S, Weiss AP, Alpert NM, Schacter DL.

Cereb Cortex. 2002 Sep;12(9):900-7.

PMID:
12183389
47.

Pharmacokinetic imaging: a noninvasive method for determining drug distribution and action.

Fischman AJ, Alpert NM, Rubin RH.

Clin Pharmacokinet. 2002;41(8):581-602. Review.

PMID:
12102642
48.

Mapping of local renal blood flow with PET and H(2)(15)O.

Alpert NM, Rabito CA, Correia DJ, Babich JW, Littman BH, Tompkins RG, Rubin NT, Rubin RH, Fischman AJ.

J Nucl Med. 2002 Apr;43(4):470-5.

49.

Regional measurement of canine skeletal muscle blood flow by positron emission tomography with H2(15)O.

Fischman AJ, Hsu H, Carter EA, Yu YM, Tompkins RG, Guerrero JL, Young VR, Alpert NM.

J Appl Physiol (1985). 2002 Apr;92(4):1709-16.

50.

Fast formation of statistically reliable FDG parametric images based on clustering and principal components.

Kimura Y, Senda M, Alpert NM.

Phys Med Biol. 2002 Feb 7;47(3):455-68.

PMID:
11848122

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