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Items: 1 to 50 of 319

1.

Visible Light Mediated Aryl Migration by Homolytic C-N Cleavage of Aryl Amines.

Alpers D, Cole KP, Stephenson CRJ.

Angew Chem Int Ed Engl. 2018 Sep 10;57(37):12167-12170. doi: 10.1002/anie.201806659. Epub 2018 Aug 15.

PMID:
30025192
2.

Another indication for the use of oral vitamin B-12 supplementation.

Alpers DH.

Am J Clin Nutr. 2018 Jul 1;108(1):1-3. doi: 10.1093/ajcn/nqy118. No abstract available.

PMID:
29982312
3.

Drug-development concepts as guides for optimizing clinical trials of supplemental zinc for populations at risk of deficiency or diarrhea.

Alpers DH, Young GP, Tran CD, Mortimer EK, Gopalsamy GL, Krebs NF, Manary MJ, Ramakrishna BS, Binder HJ, Brown IL, Miller LV.

Nutr Rev. 2017 Mar 1;75(3):147-162. doi: 10.1093/nutrit/nuw065. Review.

PMID:
28399577
4.

A Photoredox-Induced Stereoselective Dearomative Radical (4+2)-Cyclization/1,4-Addition Cascade for the Synthesis of Highly Functionalized Hexahydro-1H-carbazoles.

Alpers D, Gallhof M, Witt J, Hoffmann F, Brasholz M.

Angew Chem Int Ed Engl. 2017 Jan 24;56(5):1402-1406. doi: 10.1002/anie.201610974. Epub 2017 Jan 9.

PMID:
28067443
5.

Evidence of Subdivisions on Evolutionary Timescales in a Large, Declining Marsupial Distributed across a Phylogeographic Barrier.

Alpers DL, Walker FM, Taylor AC, Sunnucks P, Bellman S, Hansen BD, Sherwin WB.

PLoS One. 2016 Oct 12;11(10):e0162789. doi: 10.1371/journal.pone.0162789. eCollection 2016.

6.

The pharmacodynamics, safety and pharmacokinetics of single doses of the motilin agonist, camicinal, in type 1 diabetes mellitus with slow gastric emptying.

Hellström PM, Tack J, Johnson LV, Hacquoil K, Barton ME, Richards DB, Alpers DH, Sanger GJ, Dukes GE.

Br J Pharmacol. 2016 Jun;173(11):1768-77. doi: 10.1111/bph.13475. Epub 2016 Apr 13.

7.

Photoassisted oxidation of ruthenium(II)-photocatalysts Ru(bpy)3(2+) and Ru(bpz)3(2+) to RuO4: orthogonal tandem photoredox and oxidation catalysis.

Alpers D, Gallhof M, Stark CB, Brasholz M.

Chem Commun (Camb). 2016 Jan 18;52(5):1025-8. doi: 10.1039/c5cc08994h.

PMID:
26592543
8.

Absorption and blood/cellular transport of folate and cobalamin: Pharmacokinetic and physiological considerations.

Alpers DH.

Biochimie. 2016 Jul;126:52-6. doi: 10.1016/j.biochi.2015.11.006. Epub 2015 Nov 14. Review.

9.

Iridium(III) Photocatalysis: A Visible-Light-Induced Dearomatizative Tandem [4+2] Cyclization to Furnish Benzindolizidines.

Mühmel S, Alpers D, Hoffmann F, Brasholz M.

Chemistry. 2015 Aug 24;21(35):12308-12. doi: 10.1002/chem.201502572. Epub 2015 Jul 17.

PMID:
26211917
10.

Clinical Pattern of Tolvaptan-Associated Liver Injury in Subjects with Autosomal Dominant Polycystic Kidney Disease: Analysis of Clinical Trials Database.

Watkins PB, Lewis JH, Kaplowitz N, Alpers DH, Blais JD, Smotzer DM, Krasa H, Ouyang J, Torres VE, Czerwiec FS, Zimmer CA.

Drug Saf. 2015 Nov;38(11):1103-13. doi: 10.1007/s40264-015-0327-3.

11.

Introduction to the series "Best (but Oft-Forgotten) Practices".

Bier DM, Allison DB, Alpers DH, Astrup A, Cashman KD, Coates PM, Fukagawa NK, Klurfeld DM, Mattes RD, Uauy R.

Am J Clin Nutr. 2015 Aug;102(2):239-40. doi: 10.3945/ajcn.115.117697. Epub 2015 Jul 15. No abstract available.

PMID:
26178729
12.

A visible light photocatalytic cross-dehydrogenative coupling/dehydrogenation/6π-cyclization/oxidation cascade: synthesis of 12-nitroindoloisoquinolines from 2-aryltetrahydroisoquinolines.

Rusch F, Unkel LN, Alpers D, Hoffmann F, Brasholz M.

Chemistry. 2015 Jun 1;21(23):8336-40. doi: 10.1002/chem.201500612. Epub 2015 Apr 27.

PMID:
25917406
13.

The relevance of the colon to zinc nutrition.

Gopalsamy GL, Alpers DH, Binder HJ, Tran CD, Ramakrishna BS, Brown I, Manary M, Mortimer E, Young GP.

Nutrients. 2015 Jan 14;7(1):572-83. doi: 10.3390/nu7010572. Review.

14.

History and impact of nutritional epidemiology.

Alpers DH, Bier DM, Carpenter KJ, McCormick DB, Miller AB, Jacques PF.

Adv Nutr. 2014 Sep;5(5):534-6.

15.

Zinc deficiency in children with environmental enteropathy-development of new strategies: report from an expert workshop.

Young GP, Mortimer EK, Gopalsamy GL, Alpers DH, Binder HJ, Manary MJ, Ramakrishna BS, Brown IL, Brewer TG.

Am J Clin Nutr. 2014 Oct;100(4):1198-207. doi: 10.3945/ajcn.113.075036. Epub 2014 Aug 13.

16.

Clostridium butyricum MIYAIRI 588 improves high-fat diet-induced non-alcoholic fatty liver disease in rats.

Seo M, Inoue I, Tanaka M, Matsuda N, Nakano T, Awata T, Katayama S, Alpers DH, Komoda T.

Dig Dis Sci. 2013 Dec;58(12):3534-44. doi: 10.1007/s10620-013-2879-3. Epub 2013 Oct 29.

PMID:
24166662
17.

Glycoconjugated amphiphilic polymers via click-chemistry for the encapsulation of quantum dots.

Schmidtke C, Kreuziger AM, Alpers D, Jacobsen A, Leshch Y, Eggers R, Kloust H, Tran H, Ostermann J, Schotten T, Thiem J, Thimm J, Weller H.

Langmuir. 2013 Oct 8;29(40):12593-600. doi: 10.1021/la402826f. Epub 2013 Sep 26.

PMID:
24028496
18.

Vitamin B12, a fascinating micronutrient, which influences human health in the very early and later stages of life.

Guéant JL, Alpers DH.

Biochimie. 2013 May;95(5):967-9. doi: 10.1016/j.biochi.2013.02.007. Epub 2013 Feb 13. No abstract available.

PMID:
23415651
19.

Intraluminal bioavailability of divalent cations.

Alpers DH.

Curr Opin Gastroenterol. 2013 Mar;29(2):164-9. doi: 10.1097/MOG.0b013e32835d9f8e. Review. No abstract available.

PMID:
23299755
20.

Gastric intrinsic factor: the gastric and small intestinal stages of cobalamin absorption. a personal journey.

Alpers DH, Russell-Jones G.

Biochimie. 2013 May;95(5):989-94. doi: 10.1016/j.biochi.2012.12.006. Epub 2012 Dec 27. Review.

PMID:
23274574
21.

Novel in vitro model for studying hepatic ischemia-reperfusion injury using liver cubes.

DuBray BJ Jr, Conzen KD, Upadhya GA, Balachandran P, Jia J, Knolhoff BL, Alpers DH, Mohanakumar T, Chapman WC, Anderson CD.

Surgery. 2012 Aug;152(2):247-53. doi: 10.1016/j.surg.2012.02.012. Epub 2012 Jun 13.

22.

Translational approaches for pharmacotherapy development for acute diarrhea.

Donowitz M, Alpers DH, Binder HJ, Brewer T, Carrington J, Grey MJ.

Gastroenterology. 2012 Mar;142(3):e1-9. doi: 10.1053/j.gastro.2012.01.014. Epub 2012 Jan 20. No abstract available.

23.

Formation of the immunogenic α1,3-fucose epitope: elucidation of substrate specificity and of enzyme mechanism of core fucosyltransferase A.

Kötzler MP, Blank S, Behnken HN, Alpers D, Bantleon FI, Spillner E, Meyer B.

Insect Biochem Mol Biol. 2012 Feb;42(2):116-25. doi: 10.1016/j.ibmb.2011.11.004. Epub 2011 Dec 13.

PMID:
22182589
24.

Subclinical micronutrient deficiency: a problem in recognition.

Alpers DH.

Curr Opin Gastroenterol. 2012 Mar;28(2):135-8. doi: 10.1097/MOG.0b013e32834e09f8. No abstract available.

PMID:
22134221
25.

Production of ectopic gastric intrinsic factor in gastric mucosa of humans with chronic gastritis.

Shao JS, Carmel R, Alpers DH.

Dig Dis Sci. 2011 Nov;56(11):3209-19. doi: 10.1007/s10620-011-1738-3. Epub 2011 May 13.

26.

Vitamins as drugs: the importance of pharmacokinetics in oral dosing.

Alpers DH.

Curr Opin Gastroenterol. 2011 Mar;27(2):146-51. doi: 10.1097/MOG.0b013e32834172c0. No abstract available.

PMID:
21157328
27.

Measurement of intestinal protein synthesis by continuous arterial tracer application: intrinsically difficult problems arising from different protein pools and study techniques.

Hartl WH, Alpers DH, Patterson BW.

Clin Nutr. 2011 Feb;30(1):28-32. doi: 10.1016/j.clnu.2010.04.005. Epub 2010 May 21. Review.

PMID:
20493598
28.

The trophic effects of substrate, insulin, and the route of administration on protein synthesis and the preservation of small bowel mucosal mass in large mammals.

Hartl WH, Alpers DH.

Clin Nutr. 2011 Feb;30(1):20-7. doi: 10.1016/j.clnu.2010.03.002. Epub 2010 May 21. Review.

PMID:
20488593
29.

Toxicity against gastric cancer cells by combined treatment with 5-fluorouracil and mitomycin c: implication in oxidative stress.

Matsunaga T, Tsuji Y, Kaai K, Kohno S, Hirayama R, Alpers DH, Komoda T, Hara A.

Cancer Chemother Pharmacol. 2010 Aug;66(3):517-26. doi: 10.1007/s00280-009-1192-5. Epub 2009 Dec 5.

PMID:
19967538
30.

Nutrient sensing in the gastrointestinal tract.

Alpers DH.

Curr Opin Gastroenterol. 2010 Mar;26(2):134-9. doi: 10.1097/MOG.0b013e3283345809. Review. No abstract available.

PMID:
19918174
31.

Postcrystallization Analysis of the Irreproducibility of the Human Intrinsic Factor-Cobalamin Complex Crystals.

Sukumar N, Mathews FS, Gordon MM, Ealick SE, Alpers DH.

Cryst Growth Des. 2009;9(1):348-351.

32.

Garlic and its potential for prevention of colorectal cancer and other conditions.

Alpers DH.

Curr Opin Gastroenterol. 2009 Mar;25(2):116-21. doi: 10.1097/MOG.0b013e32831ef221. No abstract available.

PMID:
19528879
33.

Role of lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration.

Nakano T, Inoue I, Alpers DH, Akiba Y, Katayama S, Shinozaki R, Kaunitz JD, Ohshima S, Akita M, Takahashi S, Koyama I, Matsushita M, Komoda T.

Am J Physiol Gastrointest Liver Physiol. 2009 Jul;297(1):G207-14. doi: 10.1152/ajpgi.90590.2008. Epub 2009 Apr 30.

34.

Dietary Fat Feeding Alters Lipid Peroxidation in Surfactant-like Particles Secreted by Rat Small Intestine.

Turan A, Mahmood A, Alpers DH.

Gastroenterology Res. 2009 Apr;2(2):91-99. Epub 2009 Mar 20.

35.

Irritable bowel syndrome: more than abdominal pain and bowel habit abnormalities.

Bond B, Quinlan J, Dukes GE, Mearin F, Clouse RE, Alpers DH.

Clin Gastroenterol Hepatol. 2009 Jan;7(1):73-9. doi: 10.1016/j.cgh.2008.08.011. Epub 2008 Aug 19.

36.

Multidimensionality of symptom complexes in irritable bowel syndrome and other functional gastrointestinal disorders.

Alpers DH.

J Psychosom Res. 2008 Jun;64(6):567-72. doi: 10.1016/j.jpsychores.2008.02.023. Epub 2008 Apr 28.

PMID:
18501256
37.

The potential use of curcumin in management of chronic disease: too good to be true?

Alpers DH.

Curr Opin Gastroenterol. 2008 Mar;24(2):173-5. doi: 10.1097/MOG.0b013e3282f44a19. No abstract available.

PMID:
18301267
38.

Development of drugs for gastrointestinal motor disorders: translating science to clinical need.

Sanger GJ, Alpers DH.

Neurogastroenterol Motil. 2008 Mar;20(3):177-84. doi: 10.1111/j.1365-2982.2008.01084.x. Review.

PMID:
18257767
39.

Ray E. Clouse, MD, Washington University gastroenterologist, clinical investigator, and educator.

Gyawali CP, Sayuk GS, Alpers DH.

Gastroenterology. 2007 Nov;133(5):1404-6. No abstract available.

PMID:
17983796
40.

Crystal structure of human intrinsic factor: cobalamin complex at 2.6-A resolution.

Mathews FS, Gordon MM, Chen Z, Rajashankar KR, Ealick SE, Alpers DH, Sukumar N.

Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17311-6. Epub 2007 Oct 22.

41.

A novel phosphatase upregulated in Akp3 knockout mice.

Narisawa S, Hoylaerts MF, Doctor KS, Fukuda MN, Alpers DH, Millán JL.

Am J Physiol Gastrointest Liver Physiol. 2007 Nov;293(5):G1068-77. Epub 2007 Sep 27.

42.

Effect of the NK(3) receptor antagonist, talnetant, on rectal sensory function and compliance in healthy humans.

Houghton LA, Cremonini F, Camilleri M, Busciglio I, Fell C, Cox V, Alpers DH, Dewit OE, Dukes GE, Gray E, Lea R, Zinsmeister AR, Whorwell PJ.

Neurogastroenterol Motil. 2007 Sep;19(9):732-43.

PMID:
17727393
43.

Monitoring liver safety in drug development: the GSK experience.

Hunt CM, Papay JI, Edwards RI, Theodore D, Alpers DH, Dollery C, Debruin TW, Adkison KK, Stirnadel HA, Gibbs TG.

Regul Toxicol Pharmacol. 2007 Nov;49(2):90-100. Epub 2007 Jun 21.

PMID:
17655994
44.

Relationship of functional gastrointestinal disorders and psychiatric disorders: implications for treatment.

North CS, Hong BA, Alpers DH.

World J Gastroenterol. 2007 Apr 14;13(14):2020-7. Review.

45.

Disruption of the murine intestinal alkaline phosphatase gene Akp3 impairs lipid transcytosis and induces visceral fat accumulation and hepatic steatosis.

Nakano T, Inoue I, Koyama I, Kanazawa K, Nakamura K, Narisawa S, Tanaka K, Akita M, Masuyama T, Seo M, Hokari S, Katayama S, Alpers DH, Millán JL, Komoda T.

Am J Physiol Gastrointest Liver Physiol. 2007 May;292(5):G1439-49. Epub 2007 Mar 1.

46.

Vitamins and prevention of cardiovascular disease and cancer: should we give supplements?

Alpers DH.

Curr Opin Gastroenterol. 2007 Mar;23(2):159-63. Review. No abstract available.

PMID:
17268244
47.

The role of nutritional deficiency in the osteopenia and osteoporosis of gastrointestinal diseases.

Alpers DH.

Curr Opin Gastroenterol. 2002 Mar;18(2):203-8. No abstract available.

PMID:
17033288
48.

Is glutamine a unique fuel for small intestinal cells?

Alpers DH.

Curr Opin Gastroenterol. 2000 Mar;16(2):155.

PMID:
17024034
49.

Refeeding the malnourished patient.

Alpers DH, Klein S.

Curr Opin Gastroenterol. 1999 Mar;15(2):151-3. No abstract available.

PMID:
17023936
50.

Dietary fiber decreases colonic epithelial cell proliferation and protein synthetic rates in human subjects.

Weerasooriya V, Rennie MJ, Anant S, Alpers DH, Patterson BW, Klein S.

Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1104-8.

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