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Items: 1 to 50 of 298

1.

Engineering 4-coumaroyl-CoA derived polyketide production in Yarrowia lipolytica through a β-oxidation mediated strategy.

Palmer CM, Miller KK, Nguyen A, Alper HS.

Metab Eng. 2019 Nov 15;57:174-181. doi: 10.1016/j.ymben.2019.11.006. [Epub ahead of print]

PMID:
31740389
2.

Identification and characterization of novel xylose isomerases from a Bos taurus fecal metagenome.

Tang R, Ye P, Alper HS, Liu Z, Zhao X, Bai F.

Appl Microbiol Biotechnol. 2019 Dec;103(23-24):9465-9477. doi: 10.1007/s00253-019-10161-1. Epub 2019 Nov 7.

PMID:
31701197
3.

Yarrowia lipolytica: more than an oleaginous workhorse.

Miller KK, Alper HS.

Appl Microbiol Biotechnol. 2019 Dec;103(23-24):9251-9262. doi: 10.1007/s00253-019-10200-x. Epub 2019 Nov 4. Review.

PMID:
31686142
4.

Enhanced scale and scope of genome engineering and regulation using CRISPR/Cas in Saccharomyces cerevisiae.

Deaner M, Alper HS.

FEMS Yeast Res. 2019 Nov 1;19(7). pii: foz076. doi: 10.1093/femsyr/foz076.

PMID:
31665284
5.

Producing Biochemicals in Yarrowia lipolytica from Xylose through a Strain Mating Approach.

Li H, Alper HS.

Biotechnol J. 2019 Sep 25:e1900304. doi: 10.1002/biot.201900304. [Epub ahead of print]

PMID:
31554022
6.

Systems Metabolic Engineering Approaches for Rewiring Cells.

Alper HS, Wittmann C.

Biotechnol J. 2019 Sep;14(9):e1900312. doi: 10.1002/biot.201900312. No abstract available.

PMID:
31476113
7.

Metabolic engineering efforts for chemical products special issue.

Alper H.

Metab Eng. 2019 Aug 17. pii: S1096-7176(19)30333-7. doi: 10.1016/j.ymben.2019.08.010. [Epub ahead of print] No abstract available.

PMID:
31430536
8.

Improving ionic liquid tolerance in Saccharomyces cerevisiae through heterologous expression and directed evolution of an ILT1 homolog from Yarrowia lipolytica.

Reed KB, Wagner JM, d'Oelsnitz S, Wiggers JM, Alper HS.

J Ind Microbiol Biotechnol. 2019 Dec;46(12):1715-1724. doi: 10.1007/s10295-019-02228-9. Epub 2019 Aug 19.

PMID:
31428944
9.

Validating genome-wide CRISPR-Cas9 function improves screening in the oleaginous yeast Yarrowia lipolytica.

Schwartz C, Cheng JF, Evans R, Schwartz CA, Wagner JM, Anglin S, Beitz A, Pan W, Lonardi S, Blenner M, Alper HS, Yoshikuni Y, Wheeldon I.

Metab Eng. 2019 Sep;55:102-110. doi: 10.1016/j.ymben.2019.06.007. Epub 2019 Jun 16.

PMID:
31216436
10.

Exposure to multiple disasters: The long-term effect of Hurricane Sandy (October 29, 2012) on NYC survivors of the September 11, 2001 World Trade Center attack.

Gargano LM, Li J, Millien L, Alper H, Brackbill RM.

Psychiatry Res. 2019 Mar;273:719-724. doi: 10.1016/j.psychres.2019.01.090. Epub 2019 Jan 29.

PMID:
31207858
11.

Comparison Between Nomograms Used to Define Pediatric Aortic Arch Hypoplasia: Retrospective Evaluation Among Patients Less Than 1 Year Old with Coarctation of the Aorta.

Şişli E, Kalın S, Tuncer ON, Ayık MF, Alper H, Levent RE, Şahin H, Atay Y.

Pediatr Cardiol. 2019 Aug;40(6):1190-1198. doi: 10.1007/s00246-019-02130-2. Epub 2019 Jun 5.

PMID:
31165902
12.

Design and Evaluation of Synthetic Terminators for Regulating Mammalian Cell Transgene Expression.

Cheng JK, Morse NJ, Wagner JM, Tucker SK, Alper HS.

ACS Synth Biol. 2019 Jun 21;8(6):1263-1275. doi: 10.1021/acssynbio.8b00285. Epub 2019 May 29.

PMID:
31091408
13.

Design and synthesis of synthetic UP elements for modulation of gene expression in Escherichia coli.

Presnell KV, Flexer-Harrison M, Alper HS.

Synth Syst Biotechnol. 2019 May 2;4(2):99-106. doi: 10.1016/j.synbio.2019.04.002. eCollection 2019 Jun.

14.
15.

Systems Metabolic Engineering Meets Machine Learning: A New Era for Data-Driven Metabolic Engineering.

Presnell KV, Alper HS.

Biotechnol J. 2019 Sep;14(9):e1800416. doi: 10.1002/biot.201800416. Epub 2019 May 2. Review.

PMID:
30927499
16.

An Assessment of Long-Term Physical and Emotional Quality of Life of Persons Injured on 9/11/2001.

Brackbill RM, Alper HE, Frazier P, Gargano LM, Jacobson MH, Solomon A.

Int J Environ Res Public Health. 2019 Mar 23;16(6). pii: E1054. doi: 10.3390/ijerph16061054.

17.

Metabolic engineering of microbial cell factories for production of nutraceuticals.

Yuan SF, Alper HS.

Microb Cell Fact. 2019 Mar 11;18(1):46. doi: 10.1186/s12934-019-1096-y. Review.

18.

9/11 Residential Exposures: The Impact of World Trade Center Dust on Respiratory Outcomes of Lower Manhattan Residents.

Antao VC, Pallos LL, Graham SL, Shim YK, Sapp JH, Lewis B, Bullard S, Alper HE, Cone JE, Farfel MR, Brackbill RM.

Int J Environ Res Public Health. 2019 Mar 5;16(5). pii: E798. doi: 10.3390/ijerph16050798.

19.

CRISPR-PIN: Modifying gene position in the nucleus via dCas9-mediated tethering.

Lin JL, Ekas H, Deaner M, Alper HS.

Synth Syst Biotechnol. 2019 Feb 15;4(2):73-78. doi: 10.1016/j.synbio.2019.02.001. eCollection 2019 Jun.

20.

Ameliorating the Metabolic Burden of the Co-expression of Secreted Fungal Cellulases in a High Lipid-Accumulating Yarrowia lipolytica Strain by Medium C/N Ratio and a Chemical Chaperone.

Wei H, Wang W, Alper HS, Xu Q, Knoshaug EP, Van Wychen S, Lin CY, Luo Y, Decker SR, Himmel ME, Zhang M.

Front Microbiol. 2019 Jan 9;9:3276. doi: 10.3389/fmicb.2018.03276. eCollection 2018.

21.

Two male siblings with a novel LRBA mutation presenting with different findings of IPEX syndrome.

Eren Akarcan S, Edeer Karaca N, Aksu G, Aykut A, Yilmaz Karapinar D, Cetin F, Aydinok Y, Azarsiz E, Gambineri E, Cogulu O, Ulusoy Severcan E, Alper H, Kutukculer N.

JMM Case Rep. 2018 Oct 15;5(10):e005167. doi: 10.1099/jmmcr.0.005167. eCollection 2018 Oct.

22.

Editorial Introduction.

Alper H.

Metab Eng. 2018 Nov;50:1. doi: 10.1016/j.ymben.2018.11.005. No abstract available.

PMID:
30466949
23.

Expanding the Chemical Palette of Industrial Microbes: Metabolic Engineering for Type III PKS-Derived Polyketides.

Palmer CM, Alper HS.

Biotechnol J. 2019 Jan;14(1):e1700463. doi: 10.1002/biot.201700463. Epub 2018 Nov 19. Review.

PMID:
30358143
24.

Navigating genetic diversity by painting the bacteria red.

Palmer CM, Alper HS.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):10824-10826. doi: 10.1073/pnas.1815763115. Epub 2018 Oct 11. No abstract available.

25.

Re-experiencing 9/11-Related PTSD Symptoms Following Exposure to Hurricane Sandy.

Li J, Alper HE, Gargano LM, Maslow CB, Brackbill RM.

Int J Emerg Ment Health. 2018;20(3). doi: 10.4172/1522-4821.1000404.

26.

Recent advancements in fungal-derived fuel and chemical production and commercialization.

Ekas H, Deaner M, Alper HS.

Curr Opin Biotechnol. 2019 Jun;57:1-9. doi: 10.1016/j.copbio.2018.08.014. Epub 2018 Sep 21. Review.

PMID:
30245392
27.

Production of α-linolenic acid in Yarrowia lipolytica using low-temperature fermentation.

Cordova LT, Alper HS.

Appl Microbiol Biotechnol. 2018 Oct;102(20):8809-8816. doi: 10.1007/s00253-018-9349-y. Epub 2018 Sep 8.

PMID:
30196328
28.

Production of optically pure L(+)-lactic acid from waste plywood chips using an isolated thermotolerant Enterococcus faecalis SI at a pilot scale.

Yuan SF, Hsu TC, Wang CA, Jang MF, Kuo YC, Alper HS, Guo GL, Hwang WS.

J Ind Microbiol Biotechnol. 2018 Nov;45(11):961-970. doi: 10.1007/s10295-018-2078-5. Epub 2018 Sep 4.

PMID:
30182264
29.

Advances in CRISPR Technologies for Microbial Strain Engineering.

Alper HS, Beisel CL.

Biotechnol J. 2018 Sep;13(9):e1800460. doi: 10.1002/biot.201800460. No abstract available.

PMID:
30175907
30.

Engineering a Glucosamine-6-phosphate Responsive glmS Ribozyme Switch Enables Dynamic Control of Metabolic Flux in Bacillus subtilis for Overproduction of N-Acetylglucosamine.

Niu T, Liu Y, Li J, Koffas M, Du G, Alper HS, Liu L.

ACS Synth Biol. 2018 Oct 19;7(10):2423-2435. doi: 10.1021/acssynbio.8b00196. Epub 2018 Sep 19.

PMID:
30138558
31.

Engineering Yarrowia lipolytica for the production of cyclopropanated fatty acids.

Markham KA, Alper HS.

J Ind Microbiol Biotechnol. 2018 Oct;45(10):881-888. doi: 10.1007/s10295-018-2067-8. Epub 2018 Aug 17.

PMID:
30120620
32.

Metabolic engineering in the host Yarrowia lipolytica.

Abdel-Mawgoud AM, Markham KA, Palmer CM, Liu N, Stephanopoulos G, Alper HS.

Metab Eng. 2018 Nov;50:192-208. doi: 10.1016/j.ymben.2018.07.016. Epub 2018 Jul 26. Review.

PMID:
30056205
33.

High-efficiency transformation of Yarrowia lipolytica using electroporation.

Markham KA, Vazquez S, Alper HS.

FEMS Yeast Res. 2018 Nov 1;18(7). doi: 10.1093/femsyr/foy081.

PMID:
30052958
34.

Expanding beyond canonical metabolism: Interfacing alternative elements, synthetic biology, and metabolic engineering.

Reed KB, Alper HS.

Synth Syst Biotechnol. 2017 Dec 19;3(1):20-33. doi: 10.1016/j.synbio.2017.12.002. eCollection 2018 Mar. Review.

35.

Metabolic pathway engineering.

Alper HS, Avalos JL.

Synth Syst Biotechnol. 2018 Feb 13;3(1):1-2. doi: 10.1016/j.synbio.2018.01.002. eCollection 2018 Mar. No abstract available.

36.

Synthetic Biology Expands the Industrial Potential of Yarrowia lipolytica.

Markham KA, Alper HS.

Trends Biotechnol. 2018 Oct;36(10):1085-1095. doi: 10.1016/j.tibtech.2018.05.004. Epub 2018 Jun 4. Review.

PMID:
29880228
37.

Risk of Stroke Among Survivors of the September 11, 2001, World Trade Center Disaster.

Yu S, Alper HE, Nguyen AM, Brackbill RM.

J Occup Environ Med. 2018 Aug;60(8):e371-e376. doi: 10.1097/JOM.0000000000001361.

PMID:
29851739
38.

A comparative analysis of single cell and droplet-based FACS for improving production phenotypes: Riboflavin overproduction in Yarrowia lipolytica.

Wagner JM, Liu L, Yuan SF, Venkataraman MV, Abate AR, Alper HS.

Metab Eng. 2018 May;47:346-356. doi: 10.1016/j.ymben.2018.04.015. Epub 2018 Apr 23.

PMID:
29698778
39.

Modular Ligation Extension of Guide RNA Operons (LEGO) for Multiplexed dCas9 Regulation of Metabolic Pathways in Saccharomyces cerevisiae.

Deaner M, Holzman A, Alper HS.

Biotechnol J. 2018 Sep;13(9):e1700582. doi: 10.1002/biot.201700582. Epub 2018 Apr 29.

PMID:
29663663
40.

Condition-specific promoter activities in Saccharomyces cerevisiae.

Xiong L, Zeng Y, Tang RQ, Alper HS, Bai FW, Zhao XQ.

Microb Cell Fact. 2018 Apr 10;17(1):58. doi: 10.1186/s12934-018-0899-6.

41.

Editorial overview: Energy biotechnology: Biotechnology solutions for our energy needs.

Alper HS, Kondo A.

Curr Opin Biotechnol. 2018 Apr;50:v-vi. doi: 10.1016/j.copbio.2018.03.005. No abstract available.

PMID:
29606272
42.

T7 Polymerase Expression of Guide RNAs in vivo Allows Exportable CRISPR-Cas9 Editing in Multiple Yeast Hosts.

Morse NJ, Wagner JM, Reed KB, Gopal MR, Lauffer LH, Alper HS.

ACS Synth Biol. 2018 Apr 20;7(4):1075-1084. doi: 10.1021/acssynbio.7b00461. Epub 2018 Mar 29.

PMID:
29565571
43.

Developing a piggyBac Transposon System and Compatible Selection Markers for Insertional Mutagenesis and Genome Engineering in Yarrowia lipolytica.

Wagner JM, Williams EV, Alper HS.

Biotechnol J. 2018 May;13(5):e1800022. doi: 10.1002/biot.201800022. Epub 2018 Mar 25.

PMID:
29493878
44.

Largely enhanced bioethanol production through the combined use of lignin-modified sugarcane and xylose fermenting yeast strain.

Ko JK, Jung JH, Altpeter F, Kannan B, Kim HE, Kim KH, Alper HS, Um Y, Lee SM.

Bioresour Technol. 2018 May;256:312-320. doi: 10.1016/j.biortech.2018.01.123. Epub 2018 Feb 10.

PMID:
29455099
45.

Rewiring Yarrowia lipolytica toward triacetic acid lactone for materials generation.

Markham KA, Palmer CM, Chwatko M, Wagner JM, Murray C, Vazquez S, Swaminathan A, Chakravarty I, Lynd NA, Alper HS.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2096-2101. doi: 10.1073/pnas.1721203115. Epub 2018 Feb 12.

46.

Radiological nodule behavior: A critical parameter in the surgical management of pediatric pulmonary metastases.

Divarcı E, Arslan S, Dökümcü Z, Kantar M, Demirağ B, Öniz H, Ertan Y, Alper H, Erdener A, Özcan C.

Turk J Pediatr. 2018;60(4):372-379. doi: 10.24953/turkjped.2018.04.003.

47.

Catalytic substitution/cyclization sequences of O-substituted Isocyanates: synthesis of 1-alkoxybenzimidazolones and 1-alkoxy-3,4-dihydroquinazolin-2(1H)-ones.

Wang Q, An J, Alper H, Xiao WJ, Beauchemin AM.

Chem Commun (Camb). 2017 Dec 5;53(97):13055-13058. doi: 10.1039/c7cc07926e.

PMID:
29165447
48.

Novel pathogenic variants underlie SLC26A4-related hearing loss in a multiethnic cohort.

Cengiz FB, Yilmazer R, Olgun L, Sennaroglu L, Kirazli T, Alper H, Olgun Y, Incesulu A, Atik T, Huesca-Hernandez F, Domínguez-Aburto J, González-Rosado G, Hernandez-Zamora E, Arenas-Sordo ML, Menendez I, Orhan KS, Avci H, Mahdieh N, Bonyadi M, Foster J 2nd, Duman D, Ozkinay F, Blanton SH, Bademci G, Tekin M.

Int J Pediatr Otorhinolaryngol. 2017 Oct;101:167-171. doi: 10.1016/j.ijporl.2017.08.006. Epub 2017 Aug 8.

49.

Harnessing Microbial Cells Through Advanced Technologies and Conventional Strategies.

Bai F, Alper H.

Biotechnol J. 2017 Oct;12(10). doi: 10.1002/biot.201700558. No abstract available.

PMID:
28869360
50.

RNA-aptamers-in-droplets (RAPID) high-throughput screening for secretory phenotypes.

Abatemarco J, Sarhan MF, Wagner JM, Lin JL, Liu L, Hassouneh W, Yuan SF, Alper HS, Abate AR.

Nat Commun. 2017 Aug 23;8(1):332. doi: 10.1038/s41467-017-00425-7.

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