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Items: 1 to 50 of 245

1.

Pedigree-Defined Haplotypes and Their Applications to Genetic Studies.

Alper CA, Larsen CE.

Methods Mol Biol. 2017;1551:113-127. doi: 10.1007/978-1-4939-6750-6_6.

PMID:
28138843
2.

Dominant sequences of human major histocompatibility complex conserved extended haplotypes from HLA-DQA2 to DAXX.

Larsen CE, Alford DR, Trautwein MR, Jalloh YK, Tarnacki JL, Kunnenkeri SK, Fici DA, Yunis EJ, Awdeh ZL, Alper CA.

PLoS Genet. 2014 Oct 9;10(10):e1004637. doi: 10.1371/journal.pgen.1004637. eCollection 2014 Oct.

3.

Interaction between immunoglobulin allotypes and NK receptor genes in diabetes post-hepatitis C virus infection.

Granados-Montiel J, Zúñiga J, Azocar J, Feris EJ, Terreros D, Larsen CE, Clavijo OP, Cruz-Lagunas A, Middleton D, Alper CA, Pandey JP, Yunis EJ.

Immunobiology. 2011 Jun;216(6):686-91. doi: 10.1016/j.imbio.2010.10.006. Epub 2010 Nov 5.

4.

Frequent occurrence of conserved extended haplotypes (CEHs) in two Caucasian populations.

Szilágyi A, Bánlaki Z, Pozsonyi E, Yunis EJ, Awdeh ZL, Hossó A, Rajczy K, Larsen CE, Fici DA, Alper CA, Füst G.

Mol Immunol. 2010 Jun;47(10):1899-904. doi: 10.1016/j.molimm.2010.03.013. Epub 2010 Apr 20.

PMID:
20409590
5.

Protective KIR-HLA interactions for HCV infection in intravenous drug users.

Zúñiga J, Romero V, Azocar J, Terreros D, Vargas-Rojas MI, Torres-García D, Jiménez-Alvarez L, Vargas-Alarcón G, Granados-Montiel J, Husain Z, Chung RT, Alper CA, Yunis EJ.

Mol Immunol. 2009 Aug;46(13):2723-7. doi: 10.1016/j.molimm.2009.05.014. Epub 2009 Jun 24.

6.

The MHC type 1 diabetes susceptibility gene is centromeric to HLA-DQB1.

Husain Z, Kelly MA, Eisenbarth GS, Pugliese A, Awdeh ZL, Larsen CE, Alper CA.

J Autoimmun. 2008 Jun;30(4):266-72. Epub 2007 Dec 11.

PMID:
18065200
7.

Genetic fixity in the human major histocompatibility complex and block size diversity in the class I region including HLA-E.

Romero V, Larsen CE, Duke-Cohan JS, Fox EA, Romero T, Clavijo OP, Fici DA, Husain Z, Almeciga I, Alford DR, Awdeh ZL, Zuñiga J, El-Dahdah L, Alper CA, Yunis EJ.

BMC Genet. 2007 Apr 12;8:14.

8.

A genetic explanation for the rising incidence of type 1 diabetes, a polygenic disease.

Awdeh ZL, Yunis EJ, Audeh MJ, Fici D, Pugliese A, Larsen CE, Alper CA.

J Autoimmun. 2006 Nov;27(3):174-81. Epub 2006 Oct 17.

PMID:
17052889
9.

Incomplete penetrance of susceptibility genes for MHC-determined immunoglobulin deficiencies in monozygotic twins discordant for type 1 diabetes.

Alper CA, Husain Z, Larsen CE, Dubey DP, Stein R, Day C, Baker A, Beyan H, Hawa M, Ola TO, Leslie RD.

J Autoimmun. 2006 Sep;27(2):89-95. Epub 2006 Oct 6.

10.

Conserved extended haplotypes discriminate HLA-DR3-homozygous Basque patients with type 1 diabetes mellitus and celiac disease.

Bilbao JR, Calvo B, Aransay AM, Martin-Pagola A, Perez de Nanclares G, Aly TA, Rica I, Vitoria JC, Gaztambide S, Noble J, Fain PR, Awdeh ZL, Alper CA, Castaño L.

Genes Immun. 2006 Oct;7(7):550-4. Epub 2006 Aug 24.

PMID:
16929349
11.

Increased apoptosis of CD20+ IgA + B cells is the basis for IgA deficiency: the molecular mechanism for correction in vitro by IL-10 and CD40L.

Husain Z, Holodick N, Day C, Szymanski I, Alper CA.

J Clin Immunol. 2006 Mar;26(2):113-25. Epub 2006 Apr 26.

PMID:
16758339
12.

The haplotype structure of the human major histocompatibility complex.

Alper CA, Larsen CE, Dubey DP, Awdeh ZL, Fici DA, Yunis EJ.

Hum Immunol. 2006 Jan-Feb;67(1-2):73-84. Epub 2006 Apr 5.

PMID:
16698428
13.
14.

The genetics of HLA-associated disease.

Larsen CE, Alper CA.

Curr Opin Immunol. 2004 Oct;16(5):660-7. Review.

PMID:
15342014
15.

HLA-Cw*0409N is associated with HLA-A*2301 and HLA-B*4403-carrying haplotypes.

Pinto C, Smith AG, Larsen CE, Fernández-Viña M, Husain Z, Clavijo OP, Wang ZC, Nisperos B, Hansen JA, Alper CA, Yunis EJ.

Hum Immunol. 2004 Feb;65(2):181-7.

PMID:
14969773
16.

Immunoglobulin deficiencies and susceptibility to infection among homozygotes and heterozygotes for C2 deficiency.

Alper CA, Xu J, Cosmopoulos K, Dolinski B, Stein R, Uko G, Larsen CE, Dubey DP, Densen P, Truedsson L, Sturfelt G, Sjöholm AG.

J Clin Immunol. 2003 Jul;23(4):297-305.

PMID:
12959222
17.

Inheritable variable sizes of DNA stretches in the human MHC: conserved extended haplotypes and their fragments or blocks.

Yunis EJ, Larsen CE, Fernandez-Viña M, Awdeh ZL, Romero T, Hansen JA, Alper CA.

Tissue Antigens. 2003 Jul;62(1):1-20. Review.

PMID:
12859592
18.

CD2 engagement induces dendritic cell activation: implications for immune surveillance and T-cell activation.

Crawford K, Stark A, Kitchens B, Sternheim K, Pantazopoulos V, Triantafellow E, Wang Z, Vasir B, Larsen CE, Gabuzda D, Reinherz E, Alper CA.

Blood. 2003 Sep 1;102(5):1745-52. Epub 2003 Apr 24.

19.

Louis K. Diamond.

Alper CA, Kevy SV, Konugres AA.

Transfusion. 2002 Oct;42(10):1381-2. No abstract available.

PMID:
12449155
20.

Complex expression of natural killer receptor genes in single natural killer cells.

Husain Z, Alper CA, Yunis EJ, Dubey DP.

Immunology. 2002 Jul;106(3):373-80.

21.

HLA-Cw7 zygosity affects the size of a subset of CD158b+ natural killer cells.

Husain Z, Levitan E, Larsen CE, Mirza NM, Younes S, Yunis EJ, Alper CA, Dubey DP.

J Clin Immunol. 2002 Jan;22(1):28-36.

PMID:
11958591
22.
23.

Genetics of the complement system.

Crawford K, Alper CA.

Rev Immunogenet. 2000;2(3):323-38. Review.

PMID:
11256743
24.

Prospective analysis suggests susceptibility genes for deficiencies of IgA and several other immunoglobulins on the [HLA-B8, SC01, DR3] conserved extended haplotype.

Alper CA, Marcus-Bagley D, Awdeh Z, Kruskall MS, Eisenbarth GS, Brink SJ, Katz AJ, Stein R, Bing DH, Yunis EJ, Schur PH.

Tissue Antigens. 2000 Sep;56(3):207-16.

PMID:
11034556
25.
26.

The [HLA-B18, F1C30, DR3] conserved extended haplotype carries a susceptibility gene for IgD deficiency.

Calvo B, Castaño L, Marcus-Bagley D, Fici DA, Awdeh Z, Alper CA.

J Clin Immunol. 2000 May;20(3):216-20.

PMID:
10941830
27.

A simple estimate of the general population frequency of the MHC susceptibility gene for autoimmune polygenic disease.

Alper CA, Dubey DP, Yunis EJ, Awdeh Z.

Exp Clin Immunogenet. 2000;17(3):138-47.

PMID:
10899739
28.
29.
30.

Circulating CD2+ monocytes are dendritic cells.

Crawford K, Gabuzda D, Pantazopoulos V, Xu J, Clement C, Reinherz E, Alper CA.

J Immunol. 1999 Dec 1;163(11):5920-8.

31.

Discordance between IgA switching at the DNA level and IgA expression at the mRNA level in IgA-deficient patients.

Wang Z, Yunis D, Irigoyen M, Kitchens B, Bottaro A, Alt FW, Alper CA.

Clin Immunol. 1999 Jun;91(3):263-70.

PMID:
10370371
32.

A history of complement genetics.

Alper CA.

Exp Clin Immunogenet. 1998;15(4):203-12.

PMID:
10072630
33.

HLA-Cw alleles associated with HLA extended haplotypes and C2 deficiency.

Clavijo OP, Delgado JC, Awdeh ZL, Fici D, Turbay D, Alper CA, Truedsson L, Yunis EJ.

Tissue Antigens. 1998 Sep;52(3):282-5.

PMID:
9802610
34.

Characterization of non-expressed C4 genes in a case of complete C4 deficiency: identification of a novel point mutation leading to a premature stop codon.

Fredrikson GN, Gullstrand B, Schneider PM, Witzel-Schlömp K, Sjöholm AG, Alper CA, Awdeh Z, Truedsson L.

Hum Immunol. 1998 Nov;59(11):713-9.

PMID:
9796739
35.

Defect in Th1-like cells of nonresponders to hepatitis B vaccine.

Chedid MG, Deulofeut H, Yunis DE, Lara-Marquez ML, Salazar M, Deulofeut R, Awdeh Z, Alper CA, Yunis EJ.

Hum Immunol. 1997 Nov;58(1):42-51.

PMID:
9438208
36.

Pemphigus vulgaris autoantibody response is linked to HLA-DQB1*0503 in Pakistani patients.

Delgado JC, Hameed A, Yunis JJ, Bhol K, Rojas AI, Rehman SB, Khan AA, Ahmad M, Alper CA, Ahmed AR, Yunis EJ.

Hum Immunol. 1997 Oct;57(2):110-9.

PMID:
9438202
37.

Identical MHC markers in non-Jewish Iranian and Ashkenazi Jewish patients with pemphigus vulgaris: possible common central Asian ancestral origin.

Mobini N, Yunis EJ, Alper CA, Yunis JJ, Delgado JC, Yunis DE, Firooz A, Dowlati Y, Bahar K, Gregersen PK, Ahmed AR.

Hum Immunol. 1997 Sep 15;57(1):62-7.

PMID:
9438197
38.

Relationship between protein complotypes and DNA variant haplotypes: complotype-RFLP constellations (CRC).

Simon S, Truedsson L, Marcus-Bagley D, Awdeh Z, Eisenbarth GS, Brink SJ, Yunis EJ, Alper CA.

Hum Immunol. 1997 Sep 15;57(1):27-36.

PMID:
9438192
39.

Tumor necrosis factor constellation polymorphism and clozapine-induced agranulocytosis in two different ethnic groups.

Turbay D, Lieberman J, Alper CA, Delgado JC, Corzo D, Yunis JJ, Yunis EJ.

Blood. 1997 Jun 1;89(11):4167-74.

40.

MHC class II alleles and haplotypes in patients with pemphigus vulgaris from India.

Delgado JC, Yunis DE, Bozón MV, Salazar M, Deulofeut R, Turbay D, Mehra NK, Pasricha JS, Raval RS, Patel H, Shah BK, Bhol K, Alper CA, Ahmed AR, Yunis EJ.

Tissue Antigens. 1996 Dec;48(6):668-72.

PMID:
9008309
41.

Tumor necrosis factor (TNF) microsatellite haplotypes in relation to extended haplotypes, susceptibility to diseases associated with the major histocompatibility complex and TNF secretion.

Garcia-Merino A, Alper CA, Usuku K, Marcus-Bagley D, Lincoln R, Awdeh Z, Yunis EJ, Eisenbarth GS, Brink SJ, Hauser SL.

Hum Immunol. 1996 Sep 15;50(1):11-21.

PMID:
8872171
42.

A common major histocompatibility complex class II allele HLA-DQB1* 0301 is present in clinical variants of pemphigoid.

Delgado JC, Turbay D, Yunis EJ, Yunis JJ, Morton ED, Bhol K, Norman R, Alper CA, Good RA, Ahmed R.

Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8569-71.

44.
45.

The major histocompatibility complex region marked by HSP70-1 and HSP70-2 variants is associated with clozapine-induced agranulocytosis in two different ethnic groups.

Corzo D, Yunis JJ, Salazar M, Lieberman JA, Howard A, Awdeh Z, Alper CA, Yunis EJ.

Blood. 1995 Nov 15;86(10):3835-40.

46.

Predictability of alloreactivity among unrelated individuals: role for HLA-DPB1.

Awdeh ZL, Alper CA, Fici DA, Ronco P 2nd, Yunis EJ.

Tissue Antigens. 1995 Sep;46(3 ( Pt 1)):180-6.

PMID:
8525477
47.

HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM.

Pugliese A, Gianani R, Moromisato R, Awdeh ZL, Alper CA, Erlich HA, Jackson RA, Eisenbarth GS.

Diabetes. 1995 Jun;44(6):608-13.

PMID:
7789622
48.

The human immune response to hepatitis B surface antigen.

Alper CA.

Exp Clin Immunogenet. 1995;12(3):171-81. Review.

PMID:
8534503
49.

Linkage of familial dysalbuminemic hyperthyroxinemia to the albumin gene in a large Amish kindred.

Weiss RE, Sunthornthepvarakul T, Angkeow P, Marcus-Bagley D, Cox N, Alper CA, Refetoff S.

J Clin Endocrinol Metab. 1995 Jan;80(1):116-21.

PMID:
7829599
50.

Normal HBsAg presentation and T-cell defect in the immune response of nonresponders.

Salazar M, Deulofeut H, Granja C, Deulofeut R, Yunis DE, Marcus-Bagley D, Awdeh Z, Alper CA, Yunis EJ.

Immunogenetics. 1995;41(6):366-74.

PMID:
7759133

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