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Items: 1 to 50 of 72

1.

Early Career Members at the ERS International Congress 2017: highlights from the Assemblies.

Kahn N, Tomos I, Andrianopoulos V, Arikan H, van der Does A, Almendros I, Bonvivi S, Morgan A, Nenna R, Magouliotis D, Rutter M, De Soomer K, Nyberg A, Lundell S, Leceuvre K, Singanayagam A, Bostantzoglou C, Karmouty-Quintana H, De Brandt J.

Breathe (Sheff). 2017 Dec;13(4):e121-e129. doi: 10.1183/20734735.017617.

2.

Acetylsalicylic Acid Prevents Intermittent Hypoxia-Induced Vascular Remodeling in a Murine Model of Sleep Apnea.

Suarez-Giron MC, Castro-Grattoni A, Torres M, Farré R, Barbé F, Sánchez-de-la-Torre M, Gozal D, Picado C, Montserrat JM, Almendros I.

Front Physiol. 2018 May 24;9:600. doi: 10.3389/fphys.2018.00600. eCollection 2018.

3.

Zooming in on the ERS fellowships and the International Congress.

Nenna R, Petrarca L, Parisi GF, Almendros I, Bartel S, De Brandt J.

Breathe (Sheff). 2018 Jun;14(2):141-144. doi: 10.1183/20734735.001818.

4.

Intermittent Hypoxia Is Associated With High Hypoxia Inducible Factor-1α but Not High Vascular Endothelial Growth Factor Cell Expression in Tumors of Cutaneous Melanoma Patients.

Almendros I, Martínez-García MÁ, Campos-Rodríguez F, Riveiro-Falkenbach E, Rodríguez-Peralto JL, Nagore E, Martorell-Calatayud A, Hernández Blasco L, Bañuls Roca J, Chiner Vives E, Sánchez-de-la-Torre A, Abad-Capa J, Montserrat JM, Pérez-Gil A, Cabriada-Nuño V, Cano-Pumarega I, Corral-Peñafiel J, Diaz-Cambriles T, Mediano O, Dalmau-Arias J, Farré R, Gozal D; Spanish Sleep Network.

Front Neurol. 2018 Apr 26;9:272. doi: 10.3389/fneur.2018.00272. eCollection 2018.

5.

Exosomal Cargo Properties, Endothelial Function and Treatment of Obesity Hypoventilation Syndrome: A Proof of Concept Study.

Bhattacharjee R, Khalyfa A, Khalyfa AA, Mokhlesi B, Kheirandish-Gozal L, Almendros I, Peris E, Malhotra A, Gozal D.

J Clin Sleep Med. 2018 May 15;14(5):797-807. doi: 10.5664/jcsm.7110.

PMID:
29734990
6.

Biomarkers of carcinogenesis and tumour growth in patients with cutaneous melanoma and obstructive sleep apnoea.

Santamaria-Martos F, Benítez I, Girón C, Barbé F, Martínez-García MA, Hernández L, Montserrat JM, Nagore E, Martorell A, Campos-Rodriguez F, Corral J, Cabriada V, Abad J, Mediano O, Troncoso MF, Cano-Pumarega I, Fortuna Gutierrez AM, Diaz-Cambriles T, Somoza-Gonzalez M, Almendros I, Farre R, Gozal D, Sánchez-de-la-Torre M; Spanish Sleep Network.

Eur Respir J. 2018 Mar 15;51(3). pii: 1701885. doi: 10.1183/13993003.01885-2017. Print 2018 Mar.

PMID:
29519923
7.

Alzheimer's Disease Mutant Mice Exhibit Reduced Brain Tissue Stiffness Compared to Wild-type Mice in both Normoxia and following Intermittent Hypoxia Mimicking Sleep Apnea.

Menal MJ, Jorba I, Torres M, Montserrat JM, Gozal D, Colell A, Piñol-Ripoll G, Navajas D, Almendros I, Farré R.

Front Neurol. 2018 Jan 19;9:1. doi: 10.3389/fneur.2018.00001. eCollection 2018.

8.

Clinical physiology and sleep: insights from the European Respiratory Society Congress 2017.

Almendros I, Crespo A, Tura-Ceide O, Bonsignore MR.

J Thorac Dis. 2017 Nov;9(Suppl 16):S1532-S1536. doi: 10.21037/jtd.2017.11.44. Review. No abstract available.

9.

Temporal trajectories of novel object recognition performance in mice exposed to intermittent hypoxia.

Gozal D, Khalyfa A, Qiao Z, Almendros I, Farré R.

Eur Respir J. 2017 Dec 14;50(6). pii: 1701456. doi: 10.1183/13993003.01456-2017. Print 2017 Dec.

PMID:
29242263
10.

Early Career Members at the ERS LSC 2017: mechanistic overlap between chronic lung injury and cancer.

Almendros I, Bartel S, Bostantzoglou C, Jubrail J, Lehmann M, Wagner D.

Breathe (Sheff). 2017 Dec;13(4):323-326. doi: 10.1183/20734735.010217.

11.

Exosomes and Metabolic Function in Mice Exposed to Alternating Dark-Light Cycles Mimicking Night Shift Work Schedules.

Khalyfa A, Poroyko VA, Qiao Z, Gileles-Hillel A, Khalyfa AA, Akbarpour M, Almendros I, Farré R, Gozal D.

Front Physiol. 2017 Nov 2;8:882. doi: 10.3389/fphys.2017.00882. eCollection 2017.

12.

Bioengineered Lungs: A Challenge and An Opportunity.

Farré R, Otero J, Almendros I, Navajas D.

Arch Bronconeumol. 2018 Jan;54(1):31-38. doi: 10.1016/j.arbres.2017.09.002. Epub 2017 Nov 1. English, Spanish.

13.

Obstructive Sleep Apnea and Atherosclerosis: Both the Gut Microbiome and Hypercapnia Matter.

Almendros I, Farré N.

Am J Respir Cell Mol Biol. 2017 Nov;57(5):501-503. doi: 10.1165/rcmb.2017-0253ED. No abstract available.

PMID:
29090956
14.

Hypoxia-induced PD-L1/PD-1 crosstalk impairs T-cell function in sleep apnoea.

Cubillos-Zapata C, Avendaño-Ortiz J, Hernandez-Jimenez E, Toledano V, Casas-Martin J, Varela-Serrano A, Torres M, Almendros I, Casitas R, Fernández-Navarro I, Garcia-Sanchez A, Aguirre LA, Farre R, López-Collazo E, García-Rio F.

Eur Respir J. 2017 Oct 19;50(4). pii: 1700833. doi: 10.1183/13993003.00833-2017. Print 2017 Oct.

PMID:
29051270
15.

A prospective multicenter cohort study of cutaneous melanoma: clinical staging and potential associations with HIF-1α and VEGF expressions.

Martínez-García MÁ, Riveiro-Falkenbach E, Rodríguez-Peralto JL, Nagore E, Martorell-Calatayud A, Campos-Rodríguez F, Farré R, Hernández Blasco L, Bañuls Roca J, Chiner Vives E, Sánchez-de-la-Torre A, Abad Capa J, Montserrat JM, Almendros I, Pérez-Gil A, Cabriada Nuño V, Cano-Pumarega I, Corral Peñafiel J, Diaz Cambriles T, Mediano O, Dalmau Arias J, Gozal D; Spanish Sleep Network.

Melanoma Res. 2017 Dec;27(6):558-564. doi: 10.1097/CMR.0000000000000393.

PMID:
28885396
16.

Intermittent hypoxia and cancer: Undesirable bed partners?

Almendros I, Gozal D.

Respir Physiol Neurobiol. 2017 Aug 14. pii: S1569-9048(17)30187-8. doi: 10.1016/j.resp.2017.08.008. [Epub ahead of print] Review.

PMID:
28818483
17.

Frequency and magnitude of intermittent hypoxia modulate endothelial wound healing in a cell culture model of sleep apnea.

Campillo N, Falcones B, Montserrat JM, Gozal D, Obeso A, Gallego-Martin T, Navajas D, Almendros I, Farré R.

J Appl Physiol (1985). 2017 Nov 1;123(5):1047-1054. doi: 10.1152/japplphysiol.00077.2017. Epub 2017 Jun 22.

PMID:
28642292
18.

Intermittent hypoxia increases kidney tumor vascularization in a murine model of sleep apnea.

Vilaseca A, Campillo N, Torres M, Musquera M, Gozal D, Montserrat JM, Alcaraz A, Touijer KA, Farré R, Almendros I.

PLoS One. 2017 Jun 8;12(6):e0179444. doi: 10.1371/journal.pone.0179444. eCollection 2017.

19.

Sleep apnoea, insulin resistance and diabetes: the first step is in the fat.

Almendros I, García-Río F.

Eur Respir J. 2017 Apr 19;49(4). pii: 1700179. doi: 10.1183/13993003.00179-2017. Print 2017 Apr. No abstract available.

PMID:
28424366
20.

Altered CD8+ T-Cell Lymphocyte Function and TC1 Cell Stemness Contribute to Enhanced Malignant Tumor Properties in Murine Models of Sleep Apnea.

Akbarpour M, Khalyfa A, Qiao Z, Gileles-Hillel A, Almendros I, Farré R, Gozal D.

Sleep. 2017 Feb 1;40(2). doi: 10.1093/sleep/zsw040.

PMID:
28364502
21.

Role of Cyclooxygenase-2 on Intermittent Hypoxia-Induced Lung Tumor Malignancy in a Mouse Model of Sleep Apnea.

Campillo N, Torres M, Vilaseca A, Nonaka PN, Gozal D, Roca-Ferrer J, Picado C, Montserrat JM, Farré R, Navajas D, Almendros I.

Sci Rep. 2017 Mar 16;7:44693. doi: 10.1038/srep44693.

22.

Ageing and chronic intermittent hypoxia mimicking sleep apnea do not modify local brain tissue stiffness in healthy mice.

Jorba I, Menal MJ, Torres M, Gozal D, Piñol-Ripoll G, Colell A, Montserrat JM, Navajas D, Farré R, Almendros I.

J Mech Behav Biomed Mater. 2017 Jul;71:106-113. doi: 10.1016/j.jmbbm.2017.03.001. Epub 2017 Mar 6.

PMID:
28284842
23.

Aorta macrophage inflammatory and epigenetic changes in a murine model of obstructive sleep apnea: Potential role of CD36.

Cortese R, Gileles-Hillel A, Khalyfa A, Almendros I, Akbarpour M, Khalyfa AA, Qiao Z, Garcia T, Andrade J, Gozal D.

Sci Rep. 2017 Feb 27;7:43648. doi: 10.1038/srep43648.

24.

Chronic intermittent hypoxia mimicking sleep apnoea increases spontaneous tumorigenesis in mice.

Gallego-Martin T, Farré R, Almendros I, Gonzalez-Obeso E, Obeso A.

Eur Respir J. 2017 Feb 15;49(2). pii: 1602111. doi: 10.1183/13993003.02111-2016. Print 2017 Feb. No abstract available.

PMID:
28202553
25.

Sleep Apnea and Tumor Agressivity.

Martínez-García MÁ, Campos-Rodríguez F, Almendros I.

Arch Bronconeumol. 2017 Jun;53(6):300-301. doi: 10.1016/j.arbres.2016.10.013. Epub 2017 Jan 27. English, Spanish. No abstract available.

26.

Visceral White Adipose Tissue after Chronic Intermittent and Sustained Hypoxia in Mice.

Gozal D, Gileles-Hillel A, Cortese R, Li Y, Almendros I, Qiao Z, Khalyfa AA, Andrade J, Khalyfa A.

Am J Respir Cell Mol Biol. 2017 Apr;56(4):477-487. doi: 10.1165/rcmb.2016-0243OC.

PMID:
28107636
27.

Early effects of continuous positive airway pressure in a rodent model of allergic rhinitis.

Vilaseca I, Lehrer-Coriat E, Torres M, Aguilar F, Almendros I, Martínez-Vidal BM, Farré R, Montserrat JM.

Sleep Med. 2016 Nov - Dec;27-28:25-27. doi: 10.1016/j.sleep.2016.09.016. Epub 2016 Nov 5.

PMID:
27938914
28.

Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice.

Poroyko VA, Carreras A, Khalyfa A, Khalyfa AA, Leone V, Peris E, Almendros I, Gileles-Hillel A, Qiao Z, Hubert N, Farré R, Chang EB, Gozal D.

Sci Rep. 2016 Oct 14;6:35405. doi: 10.1038/srep35405.

29.

Tumor Cell Malignant Properties Are Enhanced by Circulating Exosomes in Sleep Apnea.

Almendros I, Khalyfa A, Trzepizur W, Gileles-Hillel A, Huang L, Akbarpour M, Andrade J, Farré R, Gozal D.

Chest. 2016 Nov;150(5):1030-1041. doi: 10.1016/j.chest.2016.08.1438. Epub 2016 Aug 26.

PMID:
27568581
30.

A Novel Chip for Cyclic Stretch and Intermittent Hypoxia Cell Exposures Mimicking Obstructive Sleep Apnea.

Campillo N, Jorba I, Schaedel L, Casals B, Gozal D, Farré R, Almendros I, Navajas D.

Front Physiol. 2016 Jul 29;7:319. doi: 10.3389/fphys.2016.00319. eCollection 2016.

31.

Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation.

Khalyfa A, Almendros I, Gileles-Hillel A, Akbarpour M, Trzepizur W, Mokhlesi B, Huang L, Andrade J, Farré R, Gozal D.

Oncotarget. 2016 Aug 23;7(34):54676-54690. doi: 10.18632/oncotarget.10578.

32.

Normoxic Recovery Mimicking Treatment of Sleep Apnea Does Not Reverse Intermittent Hypoxia-Induced Bacterial Dysbiosis and Low-Grade Endotoxemia in Mice.

Moreno-Indias I, Torres M, Sanchez-Alcoholado L, Cardona F, Almendros I, Gozal D, Montserrat JM, Queipo-Ortuño MI, Farré R.

Sleep. 2016 Oct 1;39(10):1891-1897.

33.

Heterotypic paracrine signaling drives fibroblast senescence and tumor progression of large cell carcinoma of the lung.

Lugo R, Gabasa M, Andriani F, Puig M, Facchinetti F, Ramírez J, Gómez-Caro A, Pastorino U, Fuster G, Almendros I, Gascón P, Davalos A, Reguart N, Roz L, Alcaraz J.

Oncotarget. 2016 Dec 13;7(50):82324-82337. doi: 10.18632/oncotarget.10327.

34.

Obstructive sleep apnea and Fuhrman grade in patients with clear cell renal cell carcinoma treated surgically.

Vilaseca A, Nguyen DP, Vertosick EA, Corradi RB, Musquera M, Pérez M, Fossati N, Sjoberg DD, Farré R, Almendros I, Montserrat JM, Benfante NE, Hakimi AA, Skanderup AJ, Russo P, Alcaraz A, Touijer KA.

World J Urol. 2017 Jan;35(1):51-56. doi: 10.1007/s00345-016-1830-6. Epub 2016 Apr 23.

35.

Treatment with TUG891, a free fatty acid receptor 4 agonist, restores adipose tissue metabolic dysfunction following chronic sleep fragmentation in mice.

Gozal D, Qiao Z, Almendros I, Zheng J, Khalyfa A, Shimpukade B, Ulven T.

Int J Obes (Lond). 2016 Jul;40(7):1143-9. doi: 10.1038/ijo.2016.37. Epub 2016 Mar 16.

PMID:
26980479
36.

Intermittent Hypoxia-Induced Cardiovascular Remodeling Is Reversed by Normoxia in a Mouse Model of Sleep Apnea.

Castro-Grattoni AL, Alvarez-Buvé R, Torres M, Farré R, Montserrat JM, Dalmases M, Almendros I, Barbé F, Sánchez-de-la-Torre M.

Chest. 2016 Jun;149(6):1400-8. doi: 10.1016/j.chest.2015.11.010. Epub 2016 Jan 13.

PMID:
26836908
37.

Prolonged Exposures to Intermittent Hypoxia Promote Visceral White Adipose Tissue Inflammation in a Murine Model of Severe Sleep Apnea: Effect of Normoxic Recovery.

Gileles-Hillel A, Almendros I, Khalyfa A, Nigdelioglu R, Qiao Z, Hamanaka RB, Mutlu GM, Akbarpour M, Gozal D.

Sleep. 2017 Mar 1;40(3). doi: 10.1093/sleep/zsw074.

PMID:
28329220
38.

Does obstructive sleep apnea confer risk to induce or enhance tumor malignancy?

Almendros I.

Sleep Med Rev. 2016 Jun;27:106-7. doi: 10.1016/j.smrv.2015.09.006. Epub 2015 Oct 8. No abstract available.

PMID:
26524728
39.

Microarray-based analysis of plasma cirDNA epigenetic modification profiling in xenografted mice exposed to intermittent hypoxia.

Cortese R, Almendros I, Wang Y, Gozal D.

Genom Data. 2015 May 13;5:17-20. doi: 10.1016/j.gdata.2015.05.004. eCollection 2015 Sep.

40.

Reduced NADPH oxidase type 2 activity mediates sleep fragmentation-induced effects on TC1 tumors in mice.

Zheng J, Almendros I, Wang Y, Zhang SX, Carreras A, Qiao Z, Gozal D.

Oncoimmunology. 2015 Mar 6;4(2):e976057. eCollection 2015 Feb.

41.

Relationship Between Sleep Apnea and Cancer.

Martínez-García MÁ, Campos-Rodríguez F, Almendros I, Farré R.

Arch Bronconeumol. 2015 Sep;51(9):456-61. doi: 10.1016/j.arbres.2015.02.002. Epub 2015 Apr 3. Review. English, Spanish.

42.

Adipose tissue macrophage polarization by intermittent hypoxia in a mouse model of OSA: effect of tumor microenvironment.

Almendros I, Gileles-Hillel A, Khalyfa A, Wang Y, Zhang SX, Carreras A, Farré R, Gozal D.

Cancer Lett. 2015 Jun 1;361(2):233-9. doi: 10.1016/j.canlet.2015.03.010. Epub 2015 Mar 14.

PMID:
25779675
43.

Increased upper airway collapsibility in a mouse model of Marfan syndrome.

da Palma RK, Farré R, Montserrat JM, Gorbenko Del Blanco D, Egea G, de Oliveira LV, Navajas D, Almendros I.

Respir Physiol Neurobiol. 2015 Feb 1;207:58-60. doi: 10.1016/j.resp.2014.12.013. Epub 2014 Dec 23.

PMID:
25541192
44.

Tumor circulating DNA profiling in xenografted mice exposed to intermittent hypoxia.

Cortese R, Almendros I, Wang Y, Gozal D.

Oncotarget. 2015 Jan 1;6(1):556-69.

45.

Resveratrol attenuates intermittent hypoxia-induced macrophage migration to visceral white adipose tissue and insulin resistance in male mice.

Carreras A, Zhang SX, Almendros I, Wang Y, Peris E, Qiao Z, Gozal D.

Endocrinology. 2015 Feb;156(2):437-43. doi: 10.1210/en.2014-1706. Epub 2014 Nov 18.

46.

Sex dimorphism in late gestational sleep fragmentation and metabolic dysfunction in offspring mice.

Khalyfa A, Carreras A, Almendros I, Hakim F, Gozal D.

Sleep. 2015 Apr 1;38(4):545-57. doi: 10.5665/sleep.4568.

47.

Early intermittent hypoxia induces proatherogenic changes in aortic wall macrophages in a murine model of obstructive sleep apnea.

Gileles-Hillel A, Almendros I, Khalyfa A, Zhang SX, Wang Y, Gozal D.

Am J Respir Crit Care Med. 2014 Oct 15;190(8):958-61. doi: 10.1164/rccm.201406-1149LE. No abstract available.

48.

Effect of resveratrol on visceral white adipose tissue inflammation and insulin sensitivity in a mouse model of sleep apnea.

Carreras A, Zhang SX, Peris E, Qiao Z, Wang Y, Almendros I, Gozal D.

Int J Obes (Lond). 2015 Mar;39(3):418-23. doi: 10.1038/ijo.2014.181. Epub 2014 Oct 9.

PMID:
25298275
49.

Brain tissue hypoxia and oxidative stress induced by obstructive apneas is different in young and aged rats.

Dalmases M, Torres M, Márquez-Kisinousky L, Almendros I, Planas AM, Embid C, Martínez-Garcia MÁ, Navajas D, Farré R, Montserrat JM.

Sleep. 2014 Jul 1;37(7):1249-56. doi: 10.5665/sleep.3848.

50.

Sleep apnea awakens cancer: A unifying immunological hypothesis.

Gozal D, Almendros I, Hakim F.

Oncoimmunology. 2014 Mar 27;3:e28326. eCollection 2014.

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