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Stroke in the Middle-East and North Africa: A 2-year prospective observational study of intravenous thrombolysis treatment in the region. Results from the SITS-MENA Registry.

Al-Rukn S, Mazya M, Akhtar N, Hashim H, Mansouri B, Faouzi B, Aref H, Abdulrahman H, Kesraoui S, Hentati F, Gebelly S, Ahmed N, Wahlgren N, Abd-Allah F, Almekhlafi M, Moreira T.

Int J Stroke. 2019 Oct 8:1747493019874729. doi: 10.1177/1747493019874729. [Epub ahead of print]


Antiplatelet therapy for prevention of thromboembolic complications in coiling-only procedures for unruptured brain aneurysms.

Almekhlafi MA, Al Sultan AS, Kuczynski AM, Brinjikji W, Menon BK, Hill MD, Goyal M.

J Neurointerv Surg. 2019 Sep 20. pii: neurintsurg-2019-015173. doi: 10.1136/neurintsurg-2019-015173. [Epub ahead of print]


Distribution and current problems of acute endovascular therapy for large artery occlusion from a two-year national survey in Japan.

Takagi T, Yoshimura S, Sakai N, Iihara K, Oishi H, Hirohata M, Matsumaru Y, Matsumoto Y, Yamagami H, Menon BK, Almekhlafi M, Holodinsky JK, Kamal N, Hill MD, Goyal M.

Int J Stroke. 2019 Aug 14:1747493019869706. doi: 10.1177/1747493019869706. [Epub ahead of print]


Endovascular treatment decision in acute stroke: does physician gender matter? Insights from UNMASK EVT, an international, multidisciplinary survey.

Ospel JM, Kashani N, Wilson AT, Fischer U, Campbell BCV, Sylaja PN, Yoshimura S, Rabinstein AA, Turjman F, Mitchell P, Kim BM, Cherian MP, Heo JH, Baxter BW, Podlasek A, Foss M, Menon BK, Almekhlafi MA, Demchuk AM, Hill MD, Saposnik G, Goyal M.

J Neurointerv Surg. 2019 Jul 30. pii: neurintsurg-2019-015003. doi: 10.1136/neurintsurg-2019-015003. [Epub ahead of print]


Therapeutic hypothermia: Applications in adults with acute ischemic stroke.

Kuczynski AM, Demchuk AM, Almekhlafi MA.

Brain Circ. 2019 Apr-Jun;5(2):43-54. doi: 10.4103/bc.bc_5_19. Epub 2019 Jun 27. Review.


Factors Associated With the Decision-Making on Endovascular Thrombectomy for the Management of Acute Ischemic Stroke.

Saposnik G, Menon BK, Kashani N, Wilson AT, Yoshimura S, Campbell BCV, Baxter B, Rabinstein A, Turjman F, Fischer U, Ospel JM, Mitchell PJ, Sylaja PN, Cherian M, Kim B, Heo JH, Podlasek A, Almekhlafi M, Foss MM, Demchuk AM, Hill MD, Goyal M.

Stroke. 2019 Sep;50(9):2441-2447. doi: 10.1161/STROKEAHA.119.025631. Epub 2019 Jul 22.


Time of day and endovascular treatment decision in acute stroke with relative endovascular treatment indication: insights from UNMASK EVT international survey.

Ospel JM, Kashani N, Goyal M, Menon BK, Campbell BCV, Fischer U, Turjman F, Mitchell P, Yoshimura S, Podlasek A, Rabinstein AA, Wilson AT, Kim BM, Baxter BW, Cherian MP, Heo JH, Foss M, Demchuk AM, Sylaja PN, Hill MD, Saposnik G, Almekhlafi MA.

J Neurointerv Surg. 2019 Jul 8. pii: neurintsurg-2019-014976. doi: 10.1136/neurintsurg-2019-014976. [Epub ahead of print]


Outcome of intracranial flow diversion according to the antiplatelet regimen used: a systematic review and meta-analysis.

Podlasek A, Al Sultan AA, Assis Z, Kashani N, Goyal M, Almekhlafi MA.

J Neurointerv Surg. 2019 Jul 4. pii: neurintsurg-2019-014996. doi: 10.1136/neurintsurg-2019-014996. [Epub ahead of print]


Stroke Laterality Did Not Modify Outcomes in the HERMES Meta-Analysis of Individual Patient Data of 7 Trials.

Almekhlafi MA, Hill MD, Roos YM, Campbell BCV, Muir KW, Demchuk AM, Bracard S, Gomis M, Guillemin F, Jovin TG, Menon BK, Mitchell P, White P, van der Lugt A, Saver J, Brown S, Goyal M.

Stroke. 2019 Aug;50(8):2118-2124. doi: 10.1161/STROKEAHA.118.023102. Epub 2019 Jul 5.


Platelet-Rich Emboli in Cerebral Large Vessel Occlusion Are Associated With a Large Artery Atherosclerosis Source.

Fitzgerald S, Dai D, Wang S, Douglas A, Kadirvel R, Layton KF, Thacker IC, Gounis MJ, Chueh JY, Puri AS, Almekhlafi M, Demchuk AM, Hanel RA, Sauvageau E, Aghaebrahim A, Yoo AJ, Kvamme P, M Pereira V, Kayan Y, Delgado Almandoz JE, Nogueira RG, Rabinstein AA, Kallmes DF, Doyle KM, Brinjikji W.

Stroke. 2019 Jul;50(7):1907-1910. doi: 10.1161/STROKEAHA.118.024543. Epub 2019 May 29.


Platelet-rich clots as identified by Martius Scarlet Blue staining are isodense on NCCT.

Fitzgerald ST, Wang S, Dai D, Douglas A, Kadirvel R, Gounis MJ, Chueh J, Puri AS, Layton KF, Thacker IC, Hanel RA, Sauvageau E, Aghaebrahim A, Almekhlafi MA, Demchuk AM, Nogueira RG, Pereira VM, Kvamme P, Kayan Y, Delgado Almandoz JE, Yoo AJ, Kallmes DF, Doyle KM, Brinjikji W.

J Neurointerv Surg. 2019 Nov;11(11):1145-1149. doi: 10.1136/neurintsurg-2018-014637. Epub 2019 Apr 5.


Stroke in the Middle-East and North Africa: A 2-year prospective observational study of stroke characteristics in the region-Results from the Safe Implementation of Treatments in Stroke (SITS)-Middle-East and North African (MENA).

Rukn SA, Mazya MV, Hentati F, Sassi SB, Nabli F, Said Z, Faouzi B, Hashim H, Abd-Allah F, Mansouri B, Kesraoui S, Gebeily S, Abdulrahman H, Akhtar N, Ahmed N, Wahlgren N, Aref H, Almekhlafi M, Moreira T.

Int J Stroke. 2019 Mar 12:1747493019830331. doi: 10.1177/1747493019830331. [Epub ahead of print]


Glucose Modifies the Effect of Endovascular Thrombectomy in Patients With Acute Stroke.

Chamorro Á, Brown S, Amaro S, Hill MD, Muir KW, Dippel DWJ, van Zwam W, Butcher K, Ford GA, den Hertog HM, Mitchell PJ, Demchuk AM, Majoie CBLM, Bracard S, Sibon I, Jadhav AP, Lara-Rodriguez B, van der Lugt A, Osei E, Renú A, Richard S, Rodriguez-Luna D, Donnan GA, Dixit A, Almekhlafi M, Deltour S, Epstein J, Guillon B, Bakchine S, Gomis M, du Mesnil de Rochemont R, Lopes D, Reddy V, Rudel G, Roos YBWEM, Bonafe A, Diener HC, Berkhemer OA, Cloud GC, Davis SM, van Oostenbrugge R, Guillemin F, Goyal M, Campbell BCV, Menon BK; HERMES Collaborators.

Stroke. 2019 Mar;50(3):690-696. doi: 10.1161/STROKEAHA.118.023769.


Rapid Alteplase Administration Improves Functional Outcomes in Patients With Stroke due to Large Vessel Occlusions.

Goyal M, Almekhlafi M, Dippel DW, Campbell BCV, Muir K, Demchuk AM, Bracard S, Davalos A, Guillemin F, Jovin TG, Menon BK, Mitchell PJ, Brown S, White P, Majoie CBLM, Saver JL, Hill MD; HERMES Collaborators.

Stroke. 2019 Mar;50(3):645-651. doi: 10.1161/STROKEAHA.118.021840.


Imaging of Patients with Suspected Large-Vessel Occlusion at Primary Stroke Centers: Available Modalities and a Suggested Approach.

Almekhlafi MA, Kunz WG, Menon BK, McTaggart RA, Jayaraman MV, Baxter BW, Heck D, Frei D, Derdeyn CP, Takagi T, Aamodt AH, Fragata IMR, Hill MD, Demchuk AM, Goyal M.

AJNR Am J Neuroradiol. 2019 Mar;40(3):396-400. doi: 10.3174/ajnr.A5971. Epub 2019 Jan 31.


Delayed Guillain-Barré Syndrome after Bariatric Surgery: A Report of Three Cases.

Sunbol AH, Almaghrabi S, Al Aslany SJ, Aldairi MM, Makhdum SA, Trabulsi N, Almekhlafi MA, Nassif M.

Case Rep Surg. 2018 Dec 20;2018:8413206. doi: 10.1155/2018/8413206. eCollection 2018.


Mediation of the Relationship Between Endovascular Therapy and Functional Outcome by Follow-up Infarct Volume in Patients With Acute Ischemic Stroke.

Boers AMM, Jansen IGH, Brown S, Lingsma HF, Beenen LFM, Devlin TG, Román LS, Heo JH, Ribó M, Almekhlafi MA, Liebeskind DS, Teitelbaum J, Cuadras P, du Mesnil de Rochemont R, Beaumont M, Brown MM, Yoo AJ, Donnan GA, Mas JL, Oppenheim C, Dowling RJ, Moulin T, Agrinier N, Lopes DK, Aja Rodríguez L, Compagne KCJ, Al-Ajlan FS, Madigan J, Albers GW, Soize S, Blasco J, Davis SM, Nogueira RG, Dávalos A, Menon BK, van der Lugt A, Muir KW, Roos YBWEM, White P, Mitchell PJ, Demchuk AM, van Zwam WH, Jovin TG, van Oostenbrugge RJ, Dippel DWJ, Campbell BCV, Guillemin F, Bracard S, Hill MD, Goyal M, Marquering HA, Majoie CBLM.

JAMA Neurol. 2019 Feb 1;76(2):194-202. doi: 10.1001/jamaneurol.2018.3661.


Mathematical Modeling for Decision-Making in the Field for Acute Stroke Patients With Suspected Large Vessel Occlusion.

Holodinsky JK, Almekhlafi MA, Goyal M, Kamal N.

Stroke. 2018 Oct 24:STROKEAHA118021381. doi: 10.1161/STROKEAHA.118.021381. [Epub ahead of print] No abstract available.


Rapid cardiac ventricular pacing to facilitate embolization of vein of Galen malformations: technical note.

Hockley A, Tso MK, Almekhlafi MA, Lodha AK, Clegg R, Luntley J, Eesa M, Wong JH.

J Neurosurg Pediatr. 2018 Oct 5;23(1):86-91. doi: 10.3171/2018.7.PEDS1852.


Organizing stroke systems in the field for patients with suspected large vessel occlusion acute stroke.

Almekhlafi MA, Holodinsky JK, Hill MD, Kamal N, Goyal M.

Expert Rev Cardiovasc Ther. 2019 Jan;17(1):3-9. doi: 10.1080/14779072.2019.1550717. Epub 2018 Nov 26.


Which patients with acute stroke due to proximal occlusion should not be treated with endovascular thrombectomy?

Goyal M, Almekhlafi MA, Cognard C, McTaggart R, Blackham K, Biondi A, van der Lugt A, Majoie CBLM, van Zwam WH, van der Worp HB, Hill MD.

Neuroradiology. 2019 Jan;61(1):3-8. doi: 10.1007/s00234-018-2117-y. No abstract available.


Safety of tissue plasminogen activator factor in an acute stroke patient with two unruptured cerebral aneurysms.

Sonbaa AM, Khayat AF, Almekhlafi MA.

Neurosciences (Riyadh). 2018 Oct;23(4):334-337. doi: 10.17712/nsj.2018.4.20180054.


Primary headache characters and coping strategies among medical students of Umm Al-Qura University in the Western Region of Saudi Arabia.

Khairoalsindi OA, Saber WK, Althubaiti NA, Alshareef EF, Almekhlafi MA.

Neurosciences (Riyadh). 2018 Oct;23(4):308-313. doi: 10.17712/nsj.2018.4.20180256.


Selective brain cooling: Let us have a moment of science.

Almekhlafi MA, Colbourne F, Al Sultan AS, Goyal M, Demchuk AM.

J Cereb Blood Flow Metab. 2019 Jan;39(1):182-183. doi: 10.1177/0271678X18800274. Epub 2018 Sep 14.


Distal Vessel Occlusions: When to Consider Endovascular Thrombectomy.

Kunz WG, Almekhlafi MA, Goyal M.

Stroke. 2018 Jul;49(7):1581-1583. doi: 10.1161/STROKEAHA.118.021887. Epub 2018 Jun 18. No abstract available.


Mass gathering health: Considering triggering factors associated with acute cardiovascular events using linked registry data.

Turin TC, Al Mamun M, Almekhlafi M.

Neurosciences (Riyadh). 2018 Apr;23(2):168-169. doi: 10.17712/nsj.2018.2.20180052. No abstract available.


Association of follow-up infarct volume with functional outcome in acute ischemic stroke: a pooled analysis of seven randomized trials.

Boers AMM, Jansen IGH, Beenen LFM, Devlin TG, San Roman L, Heo JH, Ribó M, Brown S, Almekhlafi MA, Liebeskind DS, Teitelbaum J, Lingsma HF, van Zwam WH, Cuadras P, du Mesnil de Rochemont R, Beaumont M, Brown MM, Yoo AJ, van Oostenbrugge RJ, Menon BK, Donnan GA, Mas JL, Roos YBWEM, Oppenheim C, van der Lugt A, Dowling RJ, Hill MD, Davalos A, Moulin T, Agrinier N, Demchuk AM, Lopes DK, Aja Rodríguez L, Dippel DWJ, Campbell BCV, Mitchell PJ, Al-Ajlan FS, Jovin TG, Madigan J, Albers GW, Soize S, Guillemin F, Reddy VK, Bracard S, Blasco J, Muir KW, Nogueira RG, White PM, Goyal M, Davis SM, Marquering HA, Majoie CBLM.

J Neurointerv Surg. 2018 Dec;10(12):1137-1142. doi: 10.1136/neurintsurg-2017-013724. Epub 2018 Apr 7.


Primary to comprehensive stroke center transfers: Appropriateness, not futility.

Goyal M, Menon BK, Wilson AT, Almekhlafi MA, McTaggart R, Jayaraman M, Demchuk AM, Hill MD.

Int J Stroke. 2018 Aug;13(6):550-553. doi: 10.1177/1747493018764072. Epub 2018 Mar 6.


Collateral Scoring on CT Angiogram Must Evaluate Phase and Regional Pattern.

Casault C, Al Sultan AS, Trivedi A, Sohn SI, Qazi E, Bokyo M, Almekhlafi M, d'Esterre C, Goyal M, Demchuk AM, Menon BK.

Can J Neurol Sci. 2017 Sep;44(5):503-507. doi: 10.1017/cjn.2017.53.


Endovascular suction thrombectomy for severe cerebral venous sinus thrombosis: A report of two cases.

Najjar AA, Rasheedi JK, Kurdi KI, Hasan AA, Almekhlafi MA, Baeesa SS.

J Taibah Univ Med Sci. 2017 Jul 21;13(1):87-92. doi: 10.1016/j.jtumed.2017.06.004. eCollection 2018 Feb.


Decompressive hemicraniectomy for malignant middle cerebral artery infarction. Experience from the Western Province of Saudi Arabia.

Algethamy HM, Samman A, Baeesa SS, Almekhlafi MA, Al Said YA, Hassan A.

Neurosciences (Riyadh). 2017 Jul;22(3):192-197. doi: 10.17712/nsj.2017.3.20170051.


Incidence and impact of stroke during Hajj. Results of 2015 Hajj stroke registry.

Almekhlafi MA, Alhazmi MA, Alsulami SS, Almorsy SA.

Neurosciences (Riyadh). 2017 Jul;22(3):181-185. doi: 10.17712/nsj.2017.3.20160246.


Regional Comparison of Multiphase Computed Tomographic Angiography and Computed Tomographic Perfusion for Prediction of Tissue Fate in Ischemic Stroke.

d'Esterre CD, Trivedi A, Pordeli P, Boesen M, Patil S, Hwan Ahn S, Najm M, Fainardi E, Shankar JJ, Rubiera M, Almekhlafi MA, Mandzia J, Khaw AV, Barber P, Coutts S, Hill MD, Demchuk AM, Sajobi T, Forkert ND, Goyal M, Lee TY, Menon BK.

Stroke. 2017 Apr;48(4):939-945. doi: 10.1161/STROKEAHA.116.015969. Epub 2017 Mar 14.


The Need for Better Data on Patients with Acute Stroke Who Are Not Treated Because of Unfavorable Imaging.

Goyal M, Menon BK, Almekhlafi MA, Demchuk A, Hill MD.

AJNR Am J Neuroradiol. 2017 Mar;38(3):424-425. doi: 10.3174/ajnr.A5094. Epub 2017 Jan 19. No abstract available.


Infarct in a New Territory After Treatment Administration in the ESCAPE Randomized Controlled Trial (Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times).

Ganesh A, Al-Ajlan FS, Sabiq F, Assis Z, Rempel JL, Butcher K, Thornton J, Kelly P, Roy D, Poppe AY, Jovin TG, Devlin T, Baxter BW, Krings T, Casaubon LK, Frei DF, Choe H, Tampieri D, Teitelbaum J, Lum C, Mandzia J, Phillips SJ, Bang OY, Almekhlafi MA, Coutts SB, Barber PA, Sajobi T, Demchuk AM, Eesa M, Hill MD, Goyal M, Menon BK; ESCAPE Trial Investigators.

Stroke. 2016 Dec;47(12):2993-2998. Epub 2016 Nov 10.


Outcome of intracranial arterial stenting of symptomatic atherosclerotic disease: A single center experience from Saudi Arabia.

Al Said Y, Kurdi K, Baeesa SS, Najjar A, Almekhlafi M, Hassan A.

Neurosciences (Riyadh). 2016 Oct;21(4):366-371. doi: 10.17712/nsj.2016.4.20160199.


Trends in one-year mortality for stroke in a tertiary academic center in Saudi Arabia: a 5-year retrospective analysis.

Almekhlafi MA.

Ann Saudi Med. 2016 May-Jun;36(3):197-202. doi: 10.5144/0256-4947.2016.197.


What constitutes the M1 segment of the middle cerebral artery?

Goyal M, Menon BK, Krings T, Patil S, Qazi E, McTaggart RA, Almekhlafi MA, Jehan R, Saver J, Jayaraman MV.

J Neurointerv Surg. 2016 Dec;8(12):1273-1277. doi: 10.1136/neurintsurg-2015-012191. Epub 2016 Jan 11.


Stroke and interventional neurology.

Almekhlafi MA.

Neurosciences (Riyadh). 2015 Oct;20(4):405-7. No abstract available.


Endovascular Therapy in Acute Ischemic Stroke: Challenges and Transition From Trials to Bedside.

Goyal M, Yu AY, Menon BK, Dippel DW, Hacke W, Davis SM, Fisher M, Yavagal DR, Turjman F, Ross J, Yoshimura S, Miao Z, Bhatia R, Almekhlafi M, Murayama Y, Sohn SI, Saver JL, Demchuk AM, Hill MD.

Stroke. 2016 Feb;47(2):548-53. doi: 10.1161/STROKEAHA.115.011426. Epub 2016 Jan 7. Review. No abstract available.


Human Immunodeficiency Virus-Associated Cerebral Aneurysmal Vasculopathy: A Systematic Review.

Baeesa SS, Bakhaidar M, Almekhlafi MA, Madani TA.

World Neurosurg. 2016 Mar;87:220-9. doi: 10.1016/j.wneu.2015.11.023. Epub 2015 Nov 23. Review.


Thrombus Characteristics Are Related to Collaterals and Angioarchitecture in Acute Stroke.

Qazi EM, Sohn SI, Mishra S, Almekhlafi MA, Eesa M, d'Esterre CD, Qazi AA, Puig J, Goyal M, Demchuk AM, Menon BK.

Can J Neurol Sci. 2015 Nov;42(6):381-8. doi: 10.1017/cjn.2015.291. Epub 2015 Sep 14.


De Novo intracerebral aneurysm in a child with acquired immunodeficiency syndrome.

Bakhaidar MG, Ahamed NA, Almekhlafi MA, Baeesa SS.

Neurosciences (Riyadh). 2015 Jul;20(3):285-91. doi: 10.17712/nsj.2015.3.20150064.


Aneurysmal subarachnoid hemorrhage affects the younger age groups in a Saudi academic center.

Bokhari YA, Batarfi AH, Alnahdi YA, Almekhlafi MA, Baeesa SS.

Ann Saudi Med. 2015 Jan-Feb;35(1):36-40. doi: 10.5144/0256-4947.2015.36.


Multiphase CT Angiography: A New Tool for the Imaging Triage of Patients with Acute Ischemic Stroke.

Menon BK, d'Esterre CD, Qazi EM, Almekhlafi M, Hahn L, Demchuk AM, Goyal M.

Radiology. 2015 May;275(2):510-20. doi: 10.1148/radiol.15142256. Epub 2015 Jan 29.


Endovascular treatment for Small Core and Anterior circulation Proximal occlusion with Emphasis on minimizing CT to recanalization times (ESCAPE) trial: methodology.

Demchuk AM, Goyal M, Menon BK, Eesa M, Ryckborst KJ, Kamal N, Patil S, Mishra S, Almekhlafi M, Randhawa PA, Roy D, Willinsky R, Montanera W, Silver FL, Shuaib A, Rempel J, Jovin T, Frei D, Sapkota B, Thornton JM, Poppe A, Tampieri D, Lum C, Weill A, Sajobi TT, Hill MD; ESCAPE Trial Investigators.

Int J Stroke. 2015 Apr;10(3):429-38. doi: 10.1111/ijs.12424. Epub 2014 Dec 25.


Stroke recurrence rates among patients with symptomatic intracranial vertebrobasilar stenoses: systematic review and meta-analysis.

Abuzinadah AR, Alanazy MH, Almekhlafi MA, Duan Y, Zhu H, Mazighi M, Lutsep HL, Donnon T, Hill MD.

J Neurointerv Surg. 2016 Feb;8(2):112-6. doi: 10.1136/neurintsurg-2014-011458. Epub 2014 Dec 11. Review.


Final infarct volume estimation on 1-week follow-up MR imaging is feasible and is dependent on recanalization status.

Krongold M, Almekhlafi MA, Demchuk AM, Coutts SB, Frayne R, Eilaghi A.

Neuroimage Clin. 2014 Nov 8;7:1-6. doi: 10.1016/j.nicl.2014.10.010. eCollection 2015.


Challenges of acute endovascular stroke trials.

Goyal M, Almekhlafi M, Menon B, Hill M, Fargen K, Parsons M, Bang OY, Siddiqui A, Andersson T, Mendes V, Davalos A, Turk A, Mocco J, Campbell B, Nogueira R, Gupta R, Murphy S, Jovin T, Khatri P, Miao Z, Demchuk A, Broderick JP, Saver J.

Stroke. 2014 Oct;45(10):3116-22. doi: 10.1161/STROKEAHA.114.006288. Epub 2014 Aug 28. No abstract available.


Antiplatelet therapy prior to temporary stent-assisted coiling.

Almekhlafi MA, Goyal M.

AJNR Am J Neuroradiol. 2014 Oct;35(10):E6. doi: 10.3174/ajnr.A4090. Epub 2014 Aug 7. No abstract available.

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