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Items: 21


Computational evidence for an early, amplified systemic inflammation program in polytrauma patients with severe extremity injuries.

Almahmoud K, Abboud A, Namas RA, Zamora R, Sperry J, Peitzman AB, Truitt MS, Gaski GE, McKinley TO, Billiar TR, Vodovotz Y.

PLoS One. 2019 Jun 4;14(6):e0217577. doi: 10.1371/journal.pone.0217577. eCollection 2019.


Antibiotics and open fractures of the lower extremity: less is more.

Bankhead-Kendall B, Gutierrez T, Murry J, Holland D, Agrawal V, Almahmoud K, Pearcy C, Truitt MS.

Eur J Trauma Emerg Surg. 2019 Feb;45(1):125-129. doi: 10.1007/s00068-017-0847-x. Epub 2017 Dec 16.


Discussion of: "Risky business? Investigating outcomes of patients undergoing urgent laparoscopic appendectomy on antithrombotic therapy".

Pearcy C, Almahmoud K, Jackson T, Hartline C, Cahill A, Spence L, Kim D, Olatubosun O, Todd SR, Campion EM, Burlew CC, Regner J, Frazee R, Michaels D, Dissanaike S, Stewart C, Foley N, Nelson P, Agrawal V, Truitt MS.

Am J Surg. 2017 Dec;214(6):1016-1017. doi: 10.1016/j.amjsurg.2017.10.012. Epub 2017 Oct 5. No abstract available.


Don't call me crazy! Delirium occurs outside of the intensive care unit.

Cahill A, Pearcy C, Almahmoud K, Agrawal V, Mani U, Sladek P, Truitt MS.

J Trauma Acute Care Surg. 2018 Jan;84(1):66-69. doi: 10.1097/TA.0000000000001728.


Risky business? Investigating outcomes of patients undergoing urgent laparoscopic appendectomy on antithrombotic therapy.

Pearcy C, Almahmoud K, Jackson T, Hartline C, Cahill A, Spence L, Kim D, Olatubosun O, Todd SR, Campion EM, Burlew CC, Regner J, Frazee R, Michaels D, Dissanaike S, Stewart C, Foley N, Nelson P, Agrawal V, Truitt MS.

Am J Surg. 2017 Dec;214(6):1012-1015. doi: 10.1016/j.amjsurg.2017.08.035. Epub 2017 Sep 19.


Impact of pelvic fractures on the early clinical outcomes of severely injured trauma patients.

Almahmoud K, Pfeifer R, Al-Kofahi K, Hmedat A, Hyderabad W, Hildebrand F, Peitzman AB, Pape HC.

Eur J Trauma Emerg Surg. 2018 Apr;44(2):155-162. doi: 10.1007/s00068-016-0754-6. Epub 2017 Jan 13.


Characterization of blunt chest trauma in a long-term porcine model of severe multiple trauma.

Horst K, Simon TP, Pfeifer R, Teuben M, Almahmoud K, Zhi Q, Santos SA, Wembers CC, Leonhardt S, Heussen N, Störmann P, Auner B, Relja B, Marzi I, Haug AT, van Griensven M, Kalbitz M, Huber-Lang M, Tolba R, Reiss LK, Uhlig S, Marx G, Pape HC, Hildebrand F.

Sci Rep. 2016 Dec 21;6:39659. doi: 10.1038/srep39659.


Elevated Admission Base Deficit Is Associated with a Complex Dynamic Network of Systemic Inflammation Which Drives Clinical Trajectories in Blunt Trauma Patients.

Abdul-Malak O, Vodovotz Y, Zaaqoq A, Guardado J, Almahmoud K, Yin J, Zuckerbraun B, Peitzman AB, Sperry J, Billiar TR, Namas RA.

Mediators Inflamm. 2016;2016:7950374. Epub 2016 Nov 15.


Trends in intubation rates and durations in ventilated severely injured trauma patients: an analysis from the TraumaRegister DGU®.

Almahmoud K, Teuben M, Andruszkow H, Horst K, Lefering R, Hildebrand F, Pape HC, Pfeifer R.

Patient Saf Surg. 2016 Nov 3;10:24. eCollection 2016.


Individual-specific principal component analysis of circulating inflammatory mediators predicts early organ dysfunction in trauma patients.

Namas RA, Almahmoud K, Mi Q, Ghuma A, Namas R, Zaaqoq A, Zhu X, Abdul-Malak O, Sperry J, Zamora R, Billiar TR, Vodovotz Y.

J Crit Care. 2016 Dec;36:146-153. doi: 10.1016/j.jcrc.2016.07.002. Epub 2016 Jul 11.


Computational Analysis Supports an Early, Type 17 Cell-Associated Divergence of Blunt Trauma Survival and Mortality.

Abboud A, Namas RA, Ramadan M, Mi Q, Almahmoud K, Abdul-Malak O, Azhar N, Zaaqoq A, Namas R, Barclay DA, Yin J, Sperry J, Peitzman A, Zamora R, Simmons RL, Billiar TR, Vodovotz Y.

Crit Care Med. 2016 Nov;44(11):e1074-e1081.


Insights into the Role of Chemokines, Damage-Associated Molecular Patterns, and Lymphocyte-Derived Mediators from Computational Models of Trauma-Induced Inflammation.

Namas RA, Mi Q, Namas R, Almahmoud K, Zaaqoq AM, Abdul-Malak O, Azhar N, Day J, Abboud A, Zamora R, Billiar TR, Vodovotz Y.

Antioxid Redox Signal. 2015 Dec 10;23(17):1370-87. doi: 10.1089/ars.2015.6398. Review.


Impact of haemorrhagic shock intensity on the dynamic of alarmins release in porcine poly-trauma animal model.

Horst K, Hildebrand F, Pfeifer R, Hübenthal S, Almahmoud K, Sassen M, Steinfeldt T, Wulf H, Ruchholtz S, Pape HC, Eschbach D.

Eur J Trauma Emerg Surg. 2016 Feb;42(1):67-75. doi: 10.1007/s00068-015-0504-1. Epub 2015 Feb 28.


Impact of Injury Severity on Dynamic Inflammation Networks Following Blunt Trauma.

Almahmoud K, Namas RA, Abdul-Malak O, Zaaqoq AM, Zamora R, Zuckerbraun BS, Sperry J, Peitzman AB, Billiar TR, Vodovotz Y.

Shock. 2015 Aug;44(2):101-9. doi: 10.1097/SHK.0000000000000395.


Trauma in silico: Individual-specific mathematical models and virtual clinical populations.

Brown D, Namas RA, Almahmoud K, Zaaqoq A, Sarkar J, Barclay DA, Yin J, Ghuma A, Abboud A, Constantine G, Nieman G, Zamora R, Chang SC, Billiar TR, Vodovotz Y.

Sci Transl Med. 2015 Apr 29;7(285):285ra61. doi: 10.1126/scitranslmed.aaa3636.


Prehospital Hypotension Is Associated With Altered Inflammation Dynamics and Worse Outcomes Following Blunt Trauma in Humans.

Almahmoud K, Namas RA, Zaaqoq AM, Abdul-Malak O, Namas R, Zamora R, Sperry J, Billiar TR, Vodovotz Y.

Crit Care Med. 2015 Jul;43(7):1395-404. doi: 10.1097/CCM.0000000000000964.


Inhalative IL-10 treatment after bilateral femoral fractures affect pulmonary inflammation in mice.

Lichte P, Pfeifer R, Kobbe P, Tohidnezhad M, Pufe T, Almahmoud K, Hildebrand F, Pape HC.

Ann Anat. 2015 Jul;200:73-8. doi: 10.1016/j.aanat.2015.02.005. Epub 2015 Mar 10.


Post-traumatic thrombo-embolic complications in polytrauma patients.

Lichte P, Kobbe P, Almahmoud K, Pfeifer R, Andruszkow H, Hildebrand F, Lefering R, Pape HC; Trauma Register DGU.

Int Orthop. 2015 May;39(5):947-54. doi: 10.1007/s00264-015-2698-6. Epub 2015 Feb 18.


Temporal Patterns of Circulating Inflammation Biomarker Networks Differentiate Susceptibility to Nosocomial Infection Following Blunt Trauma in Humans.

Namas RA, Vodovotz Y, Almahmoud K, Abdul-Malak O, Zaaqoq A, Namas R, Mi Q, Barclay D, Zuckerbraun B, Peitzman AB, Sperry J, Billiar TR.

Ann Surg. 2016 Jan;263(1):191-8. doi: 10.1097/SLA.0000000000001001.


Inducible protein-10, a potential driver of neurally controlled interleukin-10 and morbidity in human blunt trauma.

Zaaqoq AM, Namas R, Almahmoud K, Azhar N, Mi Q, Zamora R, Brienza DM, Billiar TR, Vodovotz Y.

Crit Care Med. 2014 Jun;42(6):1487-97. doi: 10.1097/CCM.0000000000000248.


Central role for MCP-1/CCL2 in injury-induced inflammation revealed by in vitro, in silico, and clinical studies.

Ziraldo C, Vodovotz Y, Namas RA, Almahmoud K, Tapias V, Mi Q, Barclay D, Jefferson BS, Chen G, Billiar TR, Zamora R.

PLoS One. 2013 Dec 3;8(12):e79804. doi: 10.1371/journal.pone.0079804. eCollection 2013.

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