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Items: 1 to 50 of 377

1.

The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape.

Weinberg DN, Papillon-Cavanagh S, Chen H, Yue Y, Chen X, Rajagopalan KN, Horth C, McGuire JT, Xu X, Nikbakht H, Lemiesz AE, Marchione DM, Marunde MR, Meiners MJ, Cheek MA, Keogh MC, Bareke E, Djedid A, Harutyunyan AS, Jabado N, Garcia BA, Li H, Allis CD, Majewski J, Lu C.

Nature. 2019 Sep;573(7773):281-286. doi: 10.1038/s41586-019-1534-3. Epub 2019 Sep 4.

PMID:
31485078
2.

Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease.

Prakash V, Carson BB, Feenstra JM, Dass RA, Sekyrova P, Hoshino A, Petersen J, Guo Y, Parks MM, Kurylo CM, Batchelder JE, Haller K, Hashimoto A, Rundqivst H, Condeelis JS, Allis CD, Drygin D, Nieto MA, Andäng M, Percipalle P, Bergh J, Adameyko I, Farrants AÖ, Hartman J, Lyden D, Pietras K, Blanchard SC, Vincent CT.

Nat Commun. 2019 May 8;10(1):2110. doi: 10.1038/s41467-019-10100-8.

3.

Target identification reveals lanosterol synthase as a vulnerability in glioma.

Phillips RE, Yang Y, Smith RC, Thompson BM, Yamasaki T, Soto-Feliciano YM, Funato K, Liang Y, Garcia-Bermudez J, Wang X, Garcia BA, Yamasaki K, McDonald JG, Birsoy K, Tabar V, Allis CD.

Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7957-7962. doi: 10.1073/pnas.1820989116. Epub 2019 Mar 28.

PMID:
30923116
4.

The expanding landscape of 'oncohistone' mutations in human cancers.

Nacev BA, Feng L, Bagert JD, Lemiesz AE, Gao J, Soshnev AA, Kundra R, Schultz N, Muir TW, Allis CD.

Nature. 2019 Mar;567(7749):473-478. doi: 10.1038/s41586-019-1038-1. Epub 2019 Mar 20.

5.

Structure-guided development of YEATS domain inhibitors by targeting π-π-π stacking.

Li X, Li XM, Jiang Y, Liu Z, Cui Y, Fung KY, van der Beelen SHE, Tian G, Wan L, Shi X, Allis CD, Li H, Li Y, Li XD.

Nat Chem Biol. 2018 Dec;14(12):1140-1149. doi: 10.1038/s41589-018-0144-y. Epub 2018 Oct 29.

6.

ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup.

Chan CS, Laddha SV, Lewis PW, Koletsky MS, Robzyk K, Da Silva E, Torres PJ, Untch BR, Li J, Bose P, Chan TA, Klimstra DS, Allis CD, Tang LH.

Nat Commun. 2018 Oct 12;9(1):4158. doi: 10.1038/s41467-018-06498-2.

7.

Pursuing the Secrets of Histone Proteins: An Amazing Journey with a Remarkable Supporting Cast.

Allis CD.

Cell. 2018 Sep 20;175(1):18-21. doi: 10.1016/j.cell.2018.08.022. Epub 2018 Sep 11. No abstract available.

PMID:
30217363
8.

Genetics, Biochemistry, and "Simple" Organisms Converge to Unlock Secrets in Histone Biology: The 2018 Albert Lasker Basic Medical Research Award.

Grunstein M, Allis CD.

JAMA. 2018 Sep 25;320(12):1233-1234. doi: 10.1001/jama.2018.12437. No abstract available.

PMID:
30208392
9.

NMDA Receptor Activation Underlies the Loss of Spinal Dorsal Horn Neurons and the Transition to Persistent Pain after Peripheral Nerve Injury.

Inquimbert P, Moll M, Latremoliere A, Tong CK, Whang J, Sheehan GF, Smith BM, Korb E, Athié MCP, Babaniyi O, Ghasemlou N, Yanagawa Y, Allis CD, Hof PR, Scholz J.

Cell Rep. 2018 May 29;23(9):2678-2689. doi: 10.1016/j.celrep.2018.04.107.

10.

Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.

Finley LWS, Vardhana SA, Carey BW, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S, Lowe SW, Allis CD, Thompson CB.

Nat Cell Biol. 2018 May;20(5):565-574. doi: 10.1038/s41556-018-0086-3. Epub 2018 Apr 16.

11.

Reading between the Lines: "ADD"-ing Histone and DNA Methylation Marks toward a New Epigenetic "Sum".

Noh KM, Allis CD, Li H.

ACS Chem Biol. 2018 Apr 20;13(4):1103. doi: 10.1021/acschembio.8b00162. Epub 2018 Mar 16. No abstract available.

PMID:
29547264
12.

Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs.

Noh KM, Wang H, Kim HR, Wenderski W, Fang F, Li CH, Dewell S, Hughes SH, Melnick AM, Patel DJ, Li H, Allis CD.

Mol Cell. 2018 Feb 1;69(3):533. doi: 10.1016/j.molcel.2018.01.014. No abstract available.

13.

Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome.

Soshnev AA, Josefowicz SZ, Allis CD.

Mol Cell. 2018 Feb 1;69(3):533. doi: 10.1016/j.molcel.2018.01.015. No abstract available.

14.

Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation.

Sabari BR, Tang Z, Huang H, Yong-Gonzalez V, Molina H, Kong HE, Dai L, Shimada M, Cross JR, Zhao Y, Roeder RG, Allis CD.

Mol Cell. 2018 Feb 1;69(3):533. doi: 10.1016/j.molcel.2018.01.013. No abstract available.

15.

Histone variant H3.3-mediated chromatin remodeling is essential for paternal genome activation in mouse preimplantation embryos.

Kong Q, Banaszynski LA, Geng F, Zhang X, Zhang J, Zhang H, O'Neill CL, Yan P, Liu Z, Shido K, Palermo GD, Allis CD, Rafii S, Rosenwaks Z, Wen D.

J Biol Chem. 2018 Mar 9;293(10):3829-3838. doi: 10.1074/jbc.RA117.001150. Epub 2018 Jan 22.

16.

NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression.

Ju J, Chen A, Deng Y, Liu M, Wang Y, Wang Y, Nie M, Wang C, Ding H, Yao B, Gui T, Li X, Xu Z, Ma C, Song Y, Kvansakul M, Zen K, Zhang CY, Luo C, Fang M, Huang DCS, Allis CD, Tan R, Zeng CK, Wei J, Zhao Q.

Nat Commun. 2017 Oct 13;8(1):928. doi: 10.1038/s41467-017-00988-5.

17.

Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition.

Korb E, Herre M, Zucker-Scharff I, Gresack J, Allis CD, Darnell RB.

Cell. 2017 Sep 7;170(6):1209-1223.e20. doi: 10.1016/j.cell.2017.07.033. Epub 2017 Aug 17.

18.

Elsässer et al. reply.

Elsässer SJ, Noh KM, Diaz N, Allis CD, Banaszynski LA.

Nature. 2017 Aug 2;548(7665):E7-E9. doi: 10.1038/nature23278. No abstract available.

PMID:
28770850
19.

ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference.

Dann GP, Liszczak GP, Bagert JD, Müller MM, Nguyen UTT, Wojcik F, Brown ZZ, Bos J, Panchenko T, Pihl R, Pollock SB, Diehl KL, Allis CD, Muir TW.

Nature. 2017 Aug 31;548(7669):607-611. doi: 10.1038/nature23671. Epub 2017 Aug 2.

20.

Opinion: On being an advisor to today's junior scientists.

Allis CD.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):5321-5323. doi: 10.1073/pnas.1704511114. No abstract available.

21.

ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.

Wan L, Wen H, Li Y, Lyu J, Xi Y, Hoshii T, Joseph JK, Wang X, Loh YE, Erb MA, Souza AL, Bradner JE, Shen L, Li W, Li H, Allis CD, Armstrong SA, Shi X.

Nature. 2017 Mar 9;543(7644):265-269. doi: 10.1038/nature21687. Epub 2017 Mar 1.

22.

SWI/SNF complex in cancer.

Lu C, Allis CD.

Nat Genet. 2017 Jan 31;49(2):178-179. doi: 10.1038/ng.3779.

23.

Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells.

Melo FR, Wallerman O, Paivandy A, Calounova G, Gustafson AM, Sabari BR, Zabucchi G, Allis CD, Pejler G.

J Allergy Clin Immunol. 2017 Aug;140(2):474-485. doi: 10.1016/j.jaci.2016.11.044. Epub 2017 Jan 17.

24.

Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas.

Papillon-Cavanagh S, Lu C, Gayden T, Mikael LG, Bechet D, Karamboulas C, Ailles L, Karamchandani J, Marchione DM, Garcia BA, Weinreb I, Goldstein D, Lewis PW, Dancu OM, Dhaliwal S, Stecho W, Howlett CJ, Mymryk JS, Barrett JW, Nichols AC, Allis CD, Majewski J, Jabado N.

Nat Genet. 2017 Feb;49(2):180-185. doi: 10.1038/ng.3757. Epub 2017 Jan 9.

25.

Metabolic regulation of gene expression through histone acylations.

Sabari BR, Zhang D, Allis CD, Zhao Y.

Nat Rev Mol Cell Biol. 2017 Feb;18(2):90-101. doi: 10.1038/nrm.2016.140. Epub 2016 Dec 7. Review.

26.

Oncogenic Mechanisms of Histone H3 Mutations.

Weinberg DN, Allis CD, Lu C.

Cold Spring Harb Perspect Med. 2017 Jan 3;7(1). pii: a026443. doi: 10.1101/cshperspect.a026443. Review.

27.

Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior.

Lepack AE, Bagot RC, Peña CJ, Loh YE, Farrelly LA, Lu Y, Powell SK, Lorsch ZS, Issler O, Cates HM, Tamminga CA, Molina H, Shen L, Nestler EJ, Allis CD, Maze I.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12562-12567. Epub 2016 Oct 18.

28.

Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2.

Xiong X, Panchenko T, Yang S, Zhao S, Yan P, Zhang W, Xie W, Li Y, Zhao Y, Allis CD, Li H.

Nat Chem Biol. 2016 Dec;12(12):1111-1118. doi: 10.1038/nchembio.2218. Epub 2016 Oct 24.

29.

Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription.

Josefowicz SZ, Shimada M, Armache A, Li CH, Miller RM, Lin S, Yang A, Dill BD, Molina H, Park HS, Garcia BA, Taunton J, Roeder RG, Allis CD.

Mol Cell. 2016 Oct 20;64(2):347-361. doi: 10.1016/j.molcel.2016.09.026.

30.

Histone arginine methylation in cocaine action in the nucleus accumbens.

Damez-Werno DM, Sun H, Scobie KN, Shao N, Rabkin J, Dias C, Calipari ES, Maze I, Pena CJ, Walker DM, Cahill ME, Chandra R, Gancarz A, Mouzon E, Landry JA, Cates H, Lobo MK, Dietz D, Allis CD, Guccione E, Turecki G, Defilippi P, Neve RL, Hurd YL, Shen L, Nestler EJ.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9623-8. doi: 10.1073/pnas.1605045113. Epub 2016 Aug 9.

31.

Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase.

Yang S, Zheng X, Lu C, Li GM, Allis CD, Li H.

Genes Dev. 2016 Jul 15;30(14):1611-6. doi: 10.1101/gad.284323.116.

32.

The molecular hallmarks of epigenetic control.

Allis CD, Jenuwein T.

Nat Rev Genet. 2016 Aug;17(8):487-500. doi: 10.1038/nrg.2016.59. Epub 2016 Jun 27. Review.

PMID:
27346641
33.

Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome.

Soshnev AA, Josefowicz SZ, Allis CD.

Mol Cell. 2016 Jun 2;62(5):681-94. doi: 10.1016/j.molcel.2016.05.004. Review. Erratum in: Mol Cell. 2018 Feb 1;69(3):533.

34.

S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.

Jayaram H, Hoelper D, Jain SU, Cantone N, Lundgren SM, Poy F, Allis CD, Cummings R, Bellon S, Lewis PW.

Proc Natl Acad Sci U S A. 2016 May 31;113(22):6182-7. doi: 10.1073/pnas.1605523113. Epub 2016 May 16.

35.

Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.

Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, Murphy D, Venneti S, Hameed M, Pawel BR, Wunder JS, Dickson BC, Lundgren SM, Jani KS, De Jay N, Papillon-Cavanagh S, Andrulis IL, Sawyer SL, Grynspan D, Turcotte RE, Nadaf J, Fahiminiyah S, Muir TW, Majewski J, Thompson CB, Chi P, Garcia BA, Allis CD, Jabado N, Lewis PW.

Science. 2016 May 13;352(6287):844-9. doi: 10.1126/science.aac7272.

36.

Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells.

Liu Y, Giannopoulou EG, Wen D, Falciatori I, Elemento O, Allis CD, Rafii S, Seandel M.

Nat Commun. 2016 Apr 27;7:11275. doi: 10.1038/ncomms11275.

37.

Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain.

Li Y, Sabari BR, Panchenko T, Wen H, Zhao D, Guan H, Wan L, Huang H, Tang Z, Zhao Y, Roeder RG, Shi X, Allis CD, Li H.

Mol Cell. 2016 Apr 21;62(2):181-193. doi: 10.1016/j.molcel.2016.03.028.

38.

YEATS2 is a selective histone crotonylation reader.

Zhao D, Guan H, Zhao S, Mi W, Wen H, Li Y, Zhao Y, Allis CD, Shi X, Li H.

Cell Res. 2016 May;26(5):629-32. doi: 10.1038/cr.2016.49. Epub 2016 Apr 22. No abstract available.

39.

Genomic aberrations frequently alter chromatin regulatory genes in chordoma.

Wang L, Zehir A, Nafa K, Zhou N, Berger MF, Casanova J, Sadowska J, Lu C, Allis CD, Gounder M, Chandhanayingyong C, Ladanyi M, Boland PJ, Hameed M.

Genes Chromosomes Cancer. 2016 Jul;55(7):591-600. doi: 10.1002/gcc.22362. Epub 2016 May 9.

40.

Reading between the Lines: "ADD"-ing Histone and DNA Methylation Marks toward a New Epigenetic "Sum".

Noh KM, Allis CD, Li H.

ACS Chem Biol. 2016 Mar 18;11(3):554-63. doi: 10.1021/acschembio.5b00830. Epub 2015 Dec 7. Review. Erratum in: ACS Chem Biol. 2018 Apr 20;13(4):1103.

41.

ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior.

Sun H, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Koo JW, Korb E, Bagot RC, Ahn FH, Cahill ME, Labonté B, Mouzon E, Heller EA, Cates H, Golden SA, Gleason K, Russo SJ, Andrews S, Neve R, Kennedy PJ, Maze I, Dietz DM, Allis CD, Turecki G, Varga-Weisz P, Tamminga C, Shen L, Nestler EJ.

Nat Med. 2015 Oct;21(10):1146-53. doi: 10.1038/nm.3939. Epub 2015 Sep 21.

42.

BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice.

Korb E, Herre M, Zucker-Scharff I, Darnell RB, Allis CD.

Nat Neurosci. 2015 Oct;18(10):1464-73. doi: 10.1038/nn.4095. Epub 2015 Aug 24.

43.

An Interactive Database for the Assessment of Histone Antibody Specificity.

Rothbart SB, Dickson BM, Raab JR, Grzybowski AT, Krajewski K, Guo AH, Shanle EK, Josefowicz SZ, Fuchs SM, Allis CD, Magnuson TR, Ruthenburg AJ, Strahl BD.

Mol Cell. 2015 Aug 6;59(3):502-11. doi: 10.1016/j.molcel.2015.06.022. Epub 2015 Jul 23.

44.

Critical Role of Histone Turnover in Neuronal Transcription and Plasticity.

Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, Rafii S, Birtwistle MR, Akbarian S, Buchholz BA, Blitzer RD, Nestler EJ, Yuan ZF, Garcia BA, Shen L, Molina H, Allis CD.

Neuron. 2015 Jul 1;87(1):77-94. doi: 10.1016/j.neuron.2015.06.014.

45.

Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs.

Noh KM, Wang H, Kim HR, Wenderski W, Fang F, Li CH, Dewell S, Hughes SH, Melnick AM, Patel DJ, Li H, Allis CD.

Mol Cell. 2015 Jul 2;59(1):89-103. doi: 10.1016/j.molcel.2015.05.017. Epub 2015 Jun 11. Erratum in: Mol Cell. 2018 Feb 1;69(3):533.

46.

"Modifying" My Career toward Chromatin Biology.

Allis CD.

J Biol Chem. 2015 Jun 26;290(26):15904-8. doi: 10.1074/jbc.X115.663229. Epub 2015 May 5. No abstract available.

47.

Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells.

Elsässer SJ, Noh KM, Diaz N, Allis CD, Banaszynski LA.

Nature. 2015 Jun 11;522(7555):240-244. doi: 10.1038/nature14345. Epub 2015 May 4.

48.

Interview with C. David Allis, PhD.

Allis CD, Glaser V.

Assay Drug Dev Technol. 2015 May;13(4):197-9. doi: 10.1089/adt.2015.1513. Epub 2015 May 4. No abstract available.

49.

Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation.

Sabari BR, Tang Z, Huang H, Yong-Gonzalez V, Molina H, Kong HE, Dai L, Shimada M, Cross JR, Zhao Y, Roeder RG, Allis CD.

Mol Cell. 2015 Apr 16;58(2):203-15. doi: 10.1016/j.molcel.2015.02.029. Epub 2015 Mar 26. Erratum in: Mol Cell. 2018 Feb 1;69(3):533.

50.

ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons.

Noh KM, Maze I, Zhao D, Xiang B, Wenderski W, Lewis PW, Shen L, Li H, Allis CD.

Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):6820-7. doi: 10.1073/pnas.1411258112. Epub 2014 Dec 23. Erratum in: Proc Natl Acad Sci U S A. 2018 Jan 30;:.

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