Sort by
Items per page

Send to

Choose Destination

Search results

Items: 35


Phasing with calcium at home.

Guo S, Campbell R, Davies PL, Allingham JS.

Acta Crystallogr F Struct Biol Commun. 2019 May 1;75(Pt 5):377-384. doi: 10.1107/S2053230X19004151. Epub 2019 Apr 26.


Effects of Modulating Actin Dynamics on HER2 Cancer Cell Motility and Metastasis.

Nersesian S, Williams R, Newsted D, Shah K, Young S, Evans PA, Allingham JS, Craig AW.

Sci Rep. 2018 Nov 22;8(1):17243. doi: 10.1038/s41598-018-35284-9.


Loss-of-function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish.

Reilly ML, Stokman MF, Magry V, Jeanpierre C, Alves M, Paydar M, Hellinga J, Delous M, Pouly D, Failler M, Martinovic J, Loeuillet L, Leroy B, Tantau J, Roume J, Gregory-Evans CY, Shan X, Filges I, Allingham JS, Kwok BH, Saunier S, Giles RH, Benmerah A.

Hum Mol Genet. 2019 Mar 1;28(5):778-795. doi: 10.1093/hmg/ddy381.


Structure and function of a lignostilbene-α,β-dioxygenase orthologue from Pseudomonas brassicacearum.

Loewen PC, Switala J, Wells JP, Huang F, Zara AT, Allingham JS, Loewen MC.

BMC Biochem. 2018 Aug 16;19(1):8. doi: 10.1186/s12858-018-0098-4.


Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate.

Trofimova D, Paydar M, Zara A, Talje L, Kwok BH, Allingham JS.

Nat Commun. 2018 Jul 6;9(1):2628. doi: 10.1038/s41467-018-05025-7.


Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice.

Guo S, Stevens CA, Vance TDR, Olijve LLC, Graham LA, Campbell RL, Yazdi SR, Escobedo C, Bar-Dolev M, Yashunsky V, Braslavsky I, Langelaan DN, Smith SP, Allingham JS, Voets IK, Davies PL.

Sci Adv. 2017 Aug 9;3(8):e1701440. doi: 10.1126/sciadv.1701440. eCollection 2017 Aug.


Peptide backbone circularization enhances antifreeze protein thermostability.

Stevens CA, Semrau J, Chiriac D, Litschko M, Campbell RL, Langelaan DN, Smith SP, Davies PL, Allingham JS.

Protein Sci. 2017 Oct;26(10):1932-1941. doi: 10.1002/pro.3228. Epub 2017 Jul 25.


Diverse modes of galacto-specific carbohydrate recognition by a family 31 glycoside hydrolase from Clostridium perfringens.

Grondin JM, Duan D, Kirlin AC, Abe KT, Chitayat S, Spencer HL, Spencer C, Campigotto A, Houliston S, Arrowsmith CH, Allingham JS, Boraston AB, Smith SP.

PLoS One. 2017 Feb 3;12(2):e0171606. doi: 10.1371/journal.pone.0171606. eCollection 2017.


Human acetyl-CoA:glucosamine-6-phosphate N-acetyltransferase 1 has a relaxed donor specificity and transfers acyl groups up to four carbons in length.

Brockhausen I, Nair DG, Chen M, Yang X, Allingham JS, Szarek WA, Anastassiades T.

Biochem Cell Biol. 2016 Apr;94(2):197-204. doi: 10.1139/bcb-2015-0115. Epub 2015 Dec 15.


Candida albicans Kinesin Kar3 Depends on a Cik1-Like Regulatory Partner Protein for Its Roles in Mating, Cell Morphogenesis, and Bipolar Spindle Formation.

Frazer C, Joshi M, Delorme C, Davis D, Bennett RJ, Allingham JS.

Eukaryot Cell. 2015 Aug;14(8):755-74. doi: 10.1128/EC.00015-15. Epub 2015 May 29.


KIF14 binds tightly to microtubules and adopts a rigor-like conformation.

Arora K, Talje L, Asenjo AB, Andersen P, Atchia K, Joshi M, Sosa H, Allingham JS, Kwok BH.

J Mol Biol. 2014 Aug 26;426(17):2997-3015. doi: 10.1016/j.jmb.2014.05.030. Epub 2014 Jun 17.


Crystal structure of calpain-3 penta-EF-hand (PEF) domain - a homodimerized PEF family member with calcium bound at the fifth EF-hand.

Partha SK, Ravulapalli R, Allingham JS, Campbell RL, Davies PL.

FEBS J. 2014 Jul;281(14):3138-49. doi: 10.1111/febs.12849. Epub 2014 Jun 9.


An antifreeze protein folds with an interior network of more than 400 semi-clathrate waters.

Sun T, Lin FH, Campbell RL, Allingham JS, Davies PL.

Science. 2014 Feb 14;343(6172):795-8. doi: 10.1126/science.1247407. Erratum in: Science. 2014 Feb 28;343(6174):969.


Kar3Vik1 mechanochemistry is inhibited by mutation or deletion of the C terminus of the Vik1 subunit.

Joshi M, Duan D, Drew D, Jia Z, Davis D, Campbell RL, Allingham JS.

J Biol Chem. 2013 Dec 27;288(52):36957-70. doi: 10.1074/jbc.M113.492264. Epub 2013 Nov 16.


Role of Ca²⁺ in folding the tandem β-sandwich extender domains of a bacterial ice-binding adhesin.

Guo S, Garnham CP, Karunan Partha S, Campbell RL, Allingham JS, Davies PL.

FEBS J. 2013 Nov;280(22):5919-32. doi: 10.1111/febs.12518. Epub 2013 Oct 11.


Crystal structure of the Candida albicans Kar3 kinesin motor domain fused to maltose-binding protein.

Delorme C, Joshi M, Allingham JS.

Biochem Biophys Res Commun. 2012 Nov 30;428(4):427-32. doi: 10.1016/j.bbrc.2012.10.101. Epub 2012 Nov 5.


Neck rotation and neck mimic docking in the noncatalytic Kar3-associated protein Vik1.

Duan D, Jia Z, Joshi M, Brunton J, Chan M, Drew D, Davis D, Allingham JS.

J Biol Chem. 2012 Nov 23;287(48):40292-301. doi: 10.1074/jbc.M112.416529. Epub 2012 Oct 7.


FES kinase promotes mast cell recruitment to mammary tumors via the stem cell factor/KIT receptor signaling axis.

Kwok E, Everingham S, Zhang S, Greer PA, Allingham JS, Craig AW.

Mol Cancer Res. 2012 Jul;10(7):881-91. doi: 10.1158/1541-7786.MCR-12-0115. Epub 2012 May 15.


Crystal structure of the Kar3-like kinesin motor domain from the filamentous fungus Ashbya gossypii.

Duan D, Hnatchuk DJ, Brenner J, Davis D, Allingham JS.

Proteins. 2012 Apr;80(4):1016-27.


Functional adaptation between yeast actin and its cognate myosin motors.

Stark BC, Wen KK, Allingham JS, Rubenstein PA, Lord M.

J Biol Chem. 2011 Sep 2;286(35):30384-92. doi: 10.1074/jbc.M111.262899. Epub 2011 Jul 7.


Biochemical characterization of UDP-Gal:GlcNAc-pyrophosphate-lipid β-1,4-Galactosyltransferase WfeD, a new enzyme from Shigella boydii type 14 that catalyzes the second step in O-antigen repeating-unit synthesis.

Xu C, Liu B, Hu B, Han Y, Feng L, Allingham JS, Szarek WA, Wang L, Brockhausen I.

J Bacteriol. 2011 Jan;193(2):449-59. doi: 10.1128/JB.00737-10. Epub 2010 Nov 5.


Two molecules of lobophorolide cooperate to stabilize an actin dimer using both their "ring" and "tail" region.

Blain JC, Mok YF, Kubanek J, Allingham JS.

Chem Biol. 2010 Aug 27;17(8):802-7. doi: 10.1016/j.chembiol.2010.06.010.


The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design.

Lucas-Lopez C, Allingham JS, Lebl T, Lawson CP, Brenk R, Sellers JR, Rayment I, Westwood NJ.

Org Biomol Chem. 2008 Jun 21;6(12):2076-84. doi: 10.1039/b801223g. Epub 2008 Apr 21.


Actin-binding toxin "tail" wags the dog.

Tanaka J, Blain JC, Allingham JS.

Chem Biol. 2008 Mar;15(3):205-7. doi: 10.1016/j.chembiol.2008.02.012.


A structural basis for regulation of actin polymerization by pectenotoxins.

Allingham JS, Miles CO, Rayment I.

J Mol Biol. 2007 Aug 24;371(4):959-70. Epub 2007 May 25.


Vik1 modulates microtubule-Kar3 interactions through a motor domain that lacks an active site.

Allingham JS, Sproul LR, Rayment I, Gilbert SP.

Cell. 2007 Mar 23;128(6):1161-72.


Actin-targeting natural products: structures, properties and mechanisms of action.

Allingham JS, Klenchin VA, Rayment I.

Cell Mol Life Sci. 2006 Sep;63(18):2119-34. Review.


Structures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activity.

Allingham JS, Zampella A, D'Auria MV, Rayment I.

Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14527-32. Epub 2005 Sep 28.


The structural basis of blebbistatin inhibition and specificity for myosin II.

Allingham JS, Smith R, Rayment I.

Nat Struct Mol Biol. 2005 Apr;12(4):378-9. Epub 2005 Mar 6.


Absolute stereochemistry of ulapualide A.

Allingham JS, Tanaka J, Marriott G, Rayment I.

Org Lett. 2004 Feb 19;6(4):597-9.


Trisoxazole macrolide toxins mimic the binding of actin-capping proteins to actin.

Klenchin VA, Allingham JS, King R, Tanaka J, Marriott G, Rayment I.

Nat Struct Biol. 2003 Dec;10(12):1058-63. Epub 2003 Oct 26.


Mechanisms of metal ion action in Tn10 transposition.

Allingham JS, Haniford DB.

J Mol Biol. 2002 May 24;319(1):53-65.


Determinants for hairpin formation in Tn10 transposition.

Allingham JS, Wardle SJ, Haniford DB.

EMBO J. 2001 Jun 1;20(11):2931-42.


The RAG1/RAG2 complex constitutes a 3' flap endonuclease: implications for junctional diversity in V(D)J and transpositional recombination.

Santagata S, Besmer E, Villa A, Bozzi F, Allingham JS, Sobacchi C, Haniford DB, Vezzoni P, Nussenzweig MC, Pan ZQ, Cortes P.

Mol Cell. 1999 Dec;4(6):935-47.


All three residues of the Tn 10 transposase DDE catalytic triad function in divalent metal ion binding.

Allingham JS, Pribil PA, Haniford DB.

J Mol Biol. 1999 Jun 25;289(5):1195-206.


Supplemental Content

Loading ...
Support Center