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Items: 39


Cathepsin B increases ENaC activity leading to hypertension early in nephrotic syndrome.

Larionov A, Dahlke E, Kunke M, Zanon Rodriguez L, Schiessl IM, Magnin JL, Kern U, Alli AA, Mollet G, Schilling O, Castrop H, Theilig F.

J Cell Mol Med. 2019 Jul 31. doi: 10.1111/jcmm.14387. [Epub ahead of print]


MAL protein stabilizes luminal membrane PLCβ3 and negatively regulates ENaC in mouse cortical collecting duct cells.

Tuna KM, Liu BC, Yue Q, Ghazi ZM, Ma HP, Eaton DC, Alli AA.

Am J Physiol Renal Physiol. 2019 Jul 31. doi: 10.1152/ajprenal.00446.2018. [Epub ahead of print]


Human genotyping and an experimental model reveal NPR-C as a possible contributor to morbidity in coarctation of the aorta.

LaDisa JF Jr, Tomita-Mitchell A, Stamm K, Bazan K, Mahnke DK, Goetsch MA, Wegter BJ, Gerringer JW, Repp K, Palygin O, Zietara AP, Krolikowski MM, Eddinger TJ, Alli AA, Mitchell ME.

Physiol Genomics. 2019 Jun 1;51(6):177-185. doi: 10.1152/physiolgenomics.00049.2018. Epub 2019 Apr 19.


Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α1-antitrypsin disposal.

Khodayari N, Oshins R, Alli AA, Tuna KM, Holliday LS, Krotova K, Brantly M.

J Biol Chem. 2019 Apr 19;294(16):6240-6252. doi: 10.1074/jbc.RA118.006142. Epub 2019 Mar 4.


Follicular fluid exosomes act on the bovine oocyte to improve oocyte competence to support development and survival to heat shock.

Rodrigues TA, Tuna KM, Alli AA, Tribulo P, Hansen PJ, Koh J, Paula-Lopes FF.

Reprod Fertil Dev. 2019 Apr;31(5):888-897. doi: 10.1071/RD18450.


Effects of magnesium chloride on in vitro cholinesterase and ATPase poisoning by organophosphate (chlorpyrifos).

Ajilore BS, Alli AA, Oluwadairo TO.

Pharmacol Res Perspect. 2018 Apr 30;6(3):e00401. doi: 10.1002/prp2.401. eCollection 2018 Jun.


Lipidomic and proteomic analysis of exosomes from mouse cortical collecting duct cells.

Dang VD, Jella KK, Ragheb RRT, Denslow ND, Alli AA.

FASEB J. 2017 Dec;31(12):5399-5408. doi: 10.1096/fj.201700417R. Epub 2017 Aug 16.


Epithelial Sodium Channel-α Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction.

Czikora I, Alli AA, Sridhar S, Matthay MA, Pillich H, Hudel M, Berisha B, Gorshkov B, Romero MJ, Gonzales J, Wu G, Huo Y, Su Y, Verin AD, Fulton D, Chakraborty T, Eaton DC, Lucas R.

Front Immunol. 2017 Jul 21;8:842. doi: 10.3389/fimmu.2017.00842. eCollection 2017.


Hydrogen Peroxide Stimulates Exosomal Cathepsin B Regulation of the Receptor for Advanced Glycation End-Products (RAGE).

Downs CA, Dang VD, Johnson NM, Denslow ND, Alli AA.

J Cell Biochem. 2018 Jan;119(1):599-606. doi: 10.1002/jcb.26219. Epub 2017 Sep 11.


ENaC activity is regulated by calpain-2 proteolysis of MARCKS proteins.

Montgomery DS, Yu L, Ghazi ZM, Thai TL, Al-Khalili O, Ma HP, Eaton DC, Alli AA.

Am J Physiol Cell Physiol. 2017 Jul 1;313(1):C42-C53. doi: 10.1152/ajpcell.00244.2016. Epub 2017 May 3.


Alveolar nonselective channels are ASIC1a/α-ENaC channels and contribute to AFC.

Trac PT, Thai TL, Linck V, Zou L, Greenlee M, Yue Q, Al-Khalili O, Alli AA, Eaton AF, Eaton DC.

Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L797-L811. doi: 10.1152/ajplung.00379.2016. Epub 2017 Mar 10.


Inhibition of TRPC6 reduces non-small cell lung cancer cell proliferation and invasion.

Yang LL, Liu BC, Lu XY, Yan Y, Zhai YJ, Bao Q, Doetsch PW, Deng X, Thai TL, Alli AA, Eaton DC, Shen BZ, Ma HP.

Oncotarget. 2017 Jan 17;8(3):5123-5134. doi: 10.18632/oncotarget.14034.


Hydrogen peroxide suppresses TRPM4 trafficking to the apical membrane in mouse cortical collecting duct principal cells.

Wu MM, Zhai YJ, Li YX, Hu QQ, Wang ZR, Wei SP, Zou L, Alli AA, Thai TL, Zhang ZR, Ma HP.

Am J Physiol Renal Physiol. 2016 Dec 1;311(6):F1360-F1368. doi: 10.1152/ajprenal.00439.2016. Epub 2016 Nov 9.


Exosomal GAPDH from Proximal Tubule Cells Regulate ENaC Activity.

Jella KK, Yu L, Yue Q, Friedman D, Duke BJ, Alli AA.

PLoS One. 2016 Nov 1;11(11):e0165763. doi: 10.1371/journal.pone.0165763. eCollection 2016.


The sodium chloride cotransporter (NCC) and epithelial sodium channel (ENaC) associate.

Mistry AC, Wynne BM, Yu L, Tomilin V, Yue Q, Zhou Y, Al-Khalili O, Mallick R, Cai H, Alli AA, Ko B, Mattheyses A, Bao HF, Pochynyuk O, Theilig F, Eaton DC, Hoover RS.

Biochem J. 2016 Oct 1;473(19):3237-52. doi: 10.1042/BCJ20160312. Epub 2016 Jul 15.


RNA-seq analysis of glycosylation related gene expression in STZ-induced diabetic rat kidney inner medulla.

Qian X, Li X, Ilori TO, Klein JD, Hughey RP, Li CJ, Alli AA, Guo Z, Yu P, Song X, Chen G.

Front Physiol. 2015 Oct 1;6:274. doi: 10.3389/fphys.2015.00274. eCollection 2015.


Calmodulin and CaMKII modulate ENaC activity by regulating the association of MARCKS and the cytoskeleton with the apical membrane.

Alli AA, Bao HF, Liu BC, Yu L, Aldrugh S, Montgomery DS, Ma HP, Eaton DC.

Am J Physiol Renal Physiol. 2015 Sep 1;309(5):F456-63. doi: 10.1152/ajprenal.00631.2014. Epub 2015 Jul 1.


Acute ethanol induces apoptosis by stimulating TRPC6 via elevation of superoxide in oxygenated podocytes.

Lu XY, Liu BC, Wang LH, Yang LL, Bao Q, Zhai YJ, Alli AA, Thai TL, Eaton DC, Wang WZ, Ma HP.

Biochim Biophys Acta. 2015 May;1853(5):965-74. doi: 10.1016/j.bbamcr.2015.01.007. Epub 2015 Jan 17.


Cytochalasin E alters the cytoskeleton and decreases ENaC activity in Xenopus 2F3 cells.

Reifenberger MS, Yu L, Bao HF, Duke BJ, Liu BC, Ma HP, Alli AA, Eaton DC, Alli AA.

Am J Physiol Renal Physiol. 2014 Jul 1;307(1):F86-95. doi: 10.1152/ajprenal.00251.2013. Epub 2014 May 14.


Chronic ethanol exposure alters the lung proteome and leads to mitochondrial dysfunction in alveolar type 2 cells.

Alli AA, Brewer EM, Montgomery DS, Ghant MS, Eaton DC, Brown LA, Helms MN.

Am J Physiol Lung Cell Mol Physiol. 2014 Jun 1;306(11):L1026-35. doi: 10.1152/ajplung.00287.2013. Epub 2014 Mar 28.


Lovastatin attenuates effects of cyclosporine A on tight junctions and apoptosis in cultured cortical collecting duct principal cells.

Liu BC, Song X, Lu XY, Fang CZ, Wei SP, Alli AA, Eaton DC, Shen BZ, Li XQ, Ma HP.

Am J Physiol Renal Physiol. 2013 Aug 1;305(3):F304-13. doi: 10.1152/ajprenal.00074.2013. Epub 2013 May 29.


WNK4 inhibition of ENaC is independent of Nedd4-2-mediated ENaC ubiquitination.

Yu L, Cai H, Yue Q, Alli AA, Wang D, Al-Khalili O, Bao HF, Eaton DC.

Am J Physiol Renal Physiol. 2013 Jul 1;305(1):F31-41. doi: 10.1152/ajprenal.00652.2012. Epub 2013 Apr 17.


Scanning ion conductance microscopy: a nanotechnology for biological studies in live cells.

Liu BC, Lu XY, Song X, Lei KY, Alli AA, Bao HF, Eaton DC, Ma HP.

Front Physiol. 2013 Jan 14;3:483. doi: 10.3389/fphys.2012.00483. eCollection 2012.


ENaC is regulated by natriuretic peptide receptor-dependent cGMP signaling.

Guo LJ, Alli AA, Eaton DC, Bao HF.

Am J Physiol Renal Physiol. 2013 Apr 1;304(7):F930-7. doi: 10.1152/ajprenal.00638.2012. Epub 2013 Jan 16.


Phosphatidylinositol phosphate-dependent regulation of Xenopus ENaC by MARCKS protein.

Alli AA, Bao HF, Alli AA, Aldrugh Y, Song JZ, Ma HP, Yu L, Al-Khalili O, Eaton DC.

Am J Physiol Renal Physiol. 2012 Sep 15;303(6):F800-11. doi: 10.1152/ajprenal.00703.2011. Epub 2012 Jul 11.


Cathepsin B is secreted apically from Xenopus 2F3 cells and cleaves the epithelial sodium channel (ENaC) to increase its activity.

Alli AA, Song JZ, Al-Khalili O, Bao HF, Ma HP, Alli AA, Eaton DC.

J Biol Chem. 2012 Aug 31;287(36):30073-83. doi: 10.1074/jbc.M111.338574. Epub 2012 Jul 10.


Molecular approaches to examine the phosphorylation state of the C type natriuretic peptide receptor.

Alli AA, Gower WR Jr.

J Cell Biochem. 2010 Jul 1;110(4):985-94. doi: 10.1002/jcb.22612.


The C type natriuretic peptide receptor tethers AHNAK1 at the plasma membrane to potentiate arachidonic acid-induced calcium mobilization.

Alli AA, Gower WR Jr.

Am J Physiol Cell Physiol. 2009 Nov;297(5):C1157-67. doi: 10.1152/ajpcell.00219.2009. Epub 2009 Aug 26.


C-type natriuretic peptide receptor expression in pancreatic alpha cells.

Burgess MD, Moore KD, Carter GM, Alli AA, Granda CS, Ichii H, Ricordi C, Gower WR Jr.

Histochem Cell Biol. 2009 Jul;132(1):95-103. doi: 10.1007/s00418-009-0591-3. Epub 2009 Apr 8.


Cardiac and kidney hormones cure up to 86% of human small-cell lung cancers in mice.

Eichelbaum EJ, Sun Y, Alli AA, Gower WR Jr, Vesely DL.

Eur J Clin Invest. 2008 Aug;38(8):562-70. doi: 10.1111/j.1365-2362.2008.01978.x.


Four cardiac hormones eliminate up to two-thirds of human breast cancers in athymic mice.

Vesely DL, Vesely BA, Eichelbaum EJ, Sun Y, Alli AA, Gower WR Jr.

In Vivo. 2007 Nov-Dec;21(6):973-8.


Four cardiac hormones cause cell death of melanoma cells and inhibit their DNA synthesis.

Vesely BA, Eichelbaum EJ, Alli AA, Sun Y, Gower WR Jr, Vesely DL.

Am J Med Sci. 2007 Nov;334(5):342-9.


Elimination of up to 80% of human pancreatic adenocarcinomas in athymic mice by cardiac hormones.

Vesely DL, Eichelbaum EJ, Sun Y, Alli AA, Vesely BA, Luther SL, Gower WR Jr.

In Vivo. 2007 May-Jun;21(3):445-51.


Four cardiac hormones eliminate up to 82% of human medullary thyroid carcinoma cells within 24 hours.

Eichelbaum EJ, Vesely BA, Alli AA, Sun Y, Gower WR Jr, Vesely DL.

Endocrine. 2006 Dec;30(3):325-32.


Four cardiac hormones eliminate 4-fold more human glioblastoma cells than the green mamba snake peptide.

Vesely BA, Eichelbaum EJ, Alli AA, Sun Y, Gower WR Jr, Vesely DL.

Cancer Lett. 2007 Aug 28;254(1):94-101. Epub 2007 Mar 30.


Urodilatin and four cardiac hormones decrease human renal carcinoma cell numbers.

Vesely BA, Eichelbaum EJ, Alli AA, Sun Y, Gower WR Jr, Vesely DL.

Eur J Clin Invest. 2006 Nov;36(11):810-9.


Four peptides decrease human colon adenocarcinoma cell number and DNA synthesis via cyclic GMP.

Gower WR, Vesely BA, Alli AA, Vesely DL.

Int J Gastrointest Cancer. 2005;36(2):77-87.


Four peptide hormones' specific decrease (up to 97%) of human prostate carcinoma cells.

Vesely BA, Alli AA, Song SJ, Gower WR Jr, Sanchez-Ramos J, Vesely DL.

Eur J Clin Invest. 2005 Nov;35(11):700-10.


Five cardiac hormones decrease the number of human small-cell lung cancer cells.

Vesely BA, Song S, Sanchez-Ramos J, Fitz SR, Alli AA, Solivan SM, Gower WR Jr, Vesely DL.

Eur J Clin Invest. 2005 Jun;35(6):388-98.


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