Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 105

1.

Photoreversible interconversion of a phytochrome photosensory module in the crystalline state.

Burgie ES, Clinger JA, Miller MD, Brewster AS, Aller P, Butryn A, Fuller FD, Gul S, Young ID, Pham CC, Kim IS, Bhowmick A, O'Riordan LJ, Sutherlin KD, Heinemann JV, Batyuk A, Alonso-Mori R, Hunter MS, Koglin JE, Yano J, Yachandra VK, Sauter NK, Cohen AE, Kern J, Orville AM, Phillips GN Jr, Vierstra RD.

Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):300-307. doi: 10.1073/pnas.1912041116. Epub 2019 Dec 18.

2.

Reducing sample consumption for serial crystallography using acoustic drop ejection.

Davy B, Axford D, Beale JH, Butryn A, Docker P, Ebrahim A, Leen G, Orville AM, Owen RL, Aller P.

J Synchrotron Radiat. 2019 Sep 1;26(Pt 5):1820-1825. doi: 10.1107/S1600577519009329. Epub 2019 Aug 16.

3.

Structures of the intermediates of Kok's photosynthetic water oxidation clock.

Kern J, Chatterjee R, Young ID, Fuller FD, Lassalle L, Ibrahim M, Gul S, Fransson T, Brewster AS, Alonso-Mori R, Hussein R, Zhang M, Douthit L, de Lichtenberg C, Cheah MH, Shevela D, Wersig J, Seuffert I, Sokaras D, Pastor E, Weninger C, Kroll T, Sierra RG, Aller P, Butryn A, Orville AM, Liang M, Batyuk A, Koglin JE, Carbajo S, Boutet S, Moriarty NW, Holton JM, Dobbek H, Adams PD, Bergmann U, Sauter NK, Zouni A, Messinger J, Yano J, Yachandra VK.

Nature. 2018 Nov;563(7731):421-425. doi: 10.1038/s41586-018-0681-2. Epub 2018 Nov 7.

4.

Gallic acid sensitizes paclitaxel-resistant human ovarian carcinoma cells through an increase in reactive oxygen species and subsequent downregulation of ERK activation.

Sánchez-Carranza JN, Díaz JF, Redondo-Horcajo M, Barasoain I, Alvarez L, Lastres P, Romero-Estrada A, Aller P, González-Maya L.

Oncol Rep. 2018 Jun;39(6):3007-3014. doi: 10.3892/or.2018.6382. Epub 2018 Apr 18.

PMID:
29693189
5.

A Novel Approach to Data Collection for Difficult Structures: Data Management for Large Numbers of Crystals with the BLEND Software.

Mylona A, Carr S, Aller P, Moraes I, Treisman R, Evans G, Foadi J.

Crystals (Basel). 2017 Aug 4;7(8):242. doi: 10.3390/cryst7080242.

6.

Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers.

Fuller FD, Gul S, Chatterjee R, Burgie ES, Young ID, Lebrette H, Srinivas V, Brewster AS, Michels-Clark T, Clinger JA, Andi B, Ibrahim M, Pastor E, de Lichtenberg C, Hussein R, Pollock CJ, Zhang M, Stan CA, Kroll T, Fransson T, Weninger C, Kubin M, Aller P, Lassalle L, Bräuer P, Miller MD, Amin M, Koroidov S, Roessler CG, Allaire M, Sierra RG, Docker PT, Glownia JM, Nelson S, Koglin JE, Zhu D, Chollet M, Song S, Lemke H, Liang M, Sokaras D, Alonso-Mori R, Zouni A, Messinger J, Bergmann U, Boal AK, Bollinger JM Jr, Krebs C, Högbom M, Phillips GN Jr, Vierstra RD, Sauter NK, Orville AM, Kern J, Yachandra VK, Yano J.

Nat Methods. 2017 Apr;14(4):443-449. doi: 10.1038/nmeth.4195. Epub 2017 Feb 27.

7.

Direct visualization of a Fe(IV)-OH intermediate in a heme enzyme.

Kwon H, Basran J, Casadei CM, Fielding AJ, Schrader TE, Ostermann A, Devos JM, Aller P, Blakeley MP, Moody PCE, Raven EL.

Nat Commun. 2016 Nov 29;7:13445. doi: 10.1038/ncomms13445.

8.

Structure of photosystem II and substrate binding at room temperature.

Young ID, Ibrahim M, Chatterjee R, Gul S, Fuller F, Koroidov S, Brewster AS, Tran R, Alonso-Mori R, Kroll T, Michels-Clark T, Laksmono H, Sierra RG, Stan CA, Hussein R, Zhang M, Douthit L, Kubin M, de Lichtenberg C, Long Vo P, Nilsson H, Cheah MH, Shevela D, Saracini C, Bean MA, Seuffert I, Sokaras D, Weng TC, Pastor E, Weninger C, Fransson T, Lassalle L, Bräuer P, Aller P, Docker PT, Andi B, Orville AM, Glownia JM, Nelson S, Sikorski M, Zhu D, Hunter MS, Lane TJ, Aquila A, Koglin JE, Robinson J, Liang M, Boutet S, Lyubimov AY, Uervirojnangkoorn M, Moriarty NW, Liebschner D, Afonine PV, Waterman DG, Evans G, Wernet P, Dobbek H, Weis WI, Brunger AT, Zwart PH, Adams PD, Zouni A, Messinger J, Bergmann U, Sauter NK, Kern J, Yachandra VK, Yano J.

Nature. 2016 Dec 15;540(7633):453-457. doi: 10.1038/nature20161. Epub 2016 Nov 21.

9.

Selected polyphenols potentiate the apoptotic efficacy of glycolytic inhibitors in human acute myeloid leukemia cell lines. Regulation by protein kinase activities.

de Blas E, Estañ MC, Del Carmen Gómez de Frutos M, Ramos J, Del Carmen Boyano-Adánez M, Aller P.

Cancer Cell Int. 2016 Sep 7;16(1):70. doi: 10.1186/s12935-016-0345-y. eCollection 2016.

10.

Applications of the BLEND Software to Crystallographic Data from Membrane Proteins.

Aller P, Geng T, Evans G, Foadi J.

Adv Exp Med Biol. 2016;922:119-135. doi: 10.1007/978-3-319-35072-1_9. Erratum in: Adv Exp Med Biol. 2016;922:E3.

11.

Applications of thin-film sandwich crystallization platforms.

Axford D, Aller P, Sanchez-Weatherby J, Sandy J.

Acta Crystallogr F Struct Biol Commun. 2016 Apr;72(Pt 4):313-9. doi: 10.1107/S2053230X16004386. Epub 2016 Mar 24.

12.

Erratum to: Applications of the BLEND Software to Crystallographic Data from Membrane Proteins.

Aller P, Geng T, Evans G, Foadi J.

Adv Exp Med Biol. 2016;922:E3. doi: 10.1007/978-3-319-35072-1_14. No abstract available.

13.

In vacuo X-ray data collection from graphene-wrapped protein crystals.

Warren AJ, Crawshaw AD, Trincao J, Aller P, Alcock S, Nistea I, Salgado PS, Evans G.

Acta Crystallogr D Biol Crystallogr. 2015 Oct;71(Pt 10):2079-88. doi: 10.1107/S1399004715014194. Epub 2015 Sep 26.

14.

Human DNA polymerase θ grasps the primer terminus to mediate DNA repair.

Zahn KE, Averill AM, Aller P, Wood RD, Doublié S.

Nat Struct Mol Biol. 2015 Apr;22(4):304-11. doi: 10.1038/nsmb.2993. Epub 2015 Mar 16.

15.

Apoptotic efficacy of etomoxir in human acute myeloid leukemia cells. Cooperation with arsenic trioxide and glycolytic inhibitors, and regulation by oxidative stress and protein kinase activities.

Estañ MC, Calviño E, Calvo S, Guillén-Guío B, Boyano-Adánez Mdel C, de Blas E, Rial E, Aller P.

PLoS One. 2014 Dec 15;9(12):e115250. doi: 10.1371/journal.pone.0115250. eCollection 2014.

16.

Application of in situ diffraction in high-throughput structure determination platforms.

Aller P, Sanchez-Weatherby J, Foadi J, Winter G, Lobley CM, Axford D, Ashton AW, Bellini D, Brandao-Neto J, Culurgioni S, Douangamath A, Duman R, Evans G, Fisher S, Flaig R, Hall DR, Lukacik P, Mazzorana M, McAuley KE, Mykhaylyk V, Owen RL, Paterson NG, Romano P, Sandy J, Sorensen T, von Delft F, Wagner A, Warren A, Williams M, Stuart DI, Walsh MA.

Methods Mol Biol. 2015;1261:233-53. doi: 10.1007/978-1-4939-2230-7_13. Review.

PMID:
25502203
17.

Mechanisms of resistance to apoptosis in the human acute promyelocytic leukemia cell line NB4.

Gañán-Gómez I, Estañ-Omaña MC, Sancho P, Aller P, Boyano-Adánez MC.

Ann Hematol. 2015 Mar;94(3):379-92. doi: 10.1007/s00277-014-2237-3. Epub 2014 Oct 18.

PMID:
25322811
18.

Regulation of death induction and chemosensitizing action of 3-bromopyruvate in myeloid leukemia cells: energy depletion, oxidative stress, and protein kinase activity modulation.

Calviño E, Estañ MC, Sánchez-Martín C, Brea R, de Blas E, Boyano-Adánez Mdel C, Rial E, Aller P.

J Pharmacol Exp Ther. 2014 Feb;348(2):324-35. doi: 10.1124/jpet.113.206714. Epub 2013 Dec 4.

PMID:
24307199
19.

Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography.

Foadi J, Aller P, Alguel Y, Cameron A, Axford D, Owen RL, Armour W, Waterman DG, Iwata S, Evans G.

Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1617-32. doi: 10.1107/S0907444913012274. Epub 2013 Jul 20.

20.

S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA.

Byrne RT, Whelan F, Aller P, Bird LE, Dowle A, Lobley CM, Reddivari Y, Nettleship JE, Owens RJ, Antson AA, Waterman DG.

Acta Crystallogr D Biol Crystallogr. 2013 Jun;69(Pt 6):1090-8. doi: 10.1107/S0907444913004939. Epub 2013 May 15.

21.

Using high-throughput in situ plate screening to evaluate the effect of dehydration on protein crystals.

Douangamath A, Aller P, Lukacik P, Sanchez-Weatherby J, Moraes I, Brandao-Neto J.

Acta Crystallogr D Biol Crystallogr. 2013 May;69(Pt 5):920-3. doi: 10.1107/S0907444913002412. Epub 2013 Apr 19.

PMID:
23633603
22.

Structure of ribose 5-phosphate isomerase from the probiotic bacterium Lactobacillus salivarius UCC118.

Lobley CM, Aller P, Douangamath A, Reddivari Y, Bumann M, Bird LE, Nettleship JE, Brandao-Neto J, Owens RJ, O'Toole PW, Walsh MA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1427-33. doi: 10.1107/S174430911204273X. Epub 2012 Nov 14.

23.

2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways.

Estañ MC, Calviño E, de Blas E, Boyano-Adánez Mdel C, Mena ML, Gómez-Gómez M, Rial E, Aller P.

Biochem Pharmacol. 2012 Dec 15;84(12):1604-16. doi: 10.1016/j.bcp.2012.09.022. Epub 2012 Oct 5.

PMID:
23041229
24.

Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanine.

Duclos S, Aller P, Jaruga P, Dizdaroglu M, Wallace SS, Doublié S.

DNA Repair (Amst). 2012 Sep 1;11(9):714-25. doi: 10.1016/j.dnarep.2012.06.004. Epub 2012 Jul 11.

25.

Identification of virtual signal transducers and activators of transcription response elements in the human insulin receptor gene promoter.

Calle C, Aller P, García-Arencibia M.

Comput Biol Chem. 2011 Dec 14;35(6):333-5. doi: 10.1016/j.compbiolchem.2011.10.001. Epub 2011 Oct 7.

PMID:
22099628
26.

Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells. Reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation.

Calviño E, Estañ MC, Simón GP, Sancho P, Boyano-Adánez Mdel C, de Blas E, Bréard J, Aller P.

Biochem Pharmacol. 2011 Dec 1;82(11):1619-29. doi: 10.1016/j.bcp.2011.08.017. Epub 2011 Aug 27.

PMID:
21889928
27.

A crystallographic study of the role of sequence context in thymine glycol bypass by a replicative DNA polymerase serendipitously sheds light on the exonuclease complex.

Aller P, Duclos S, Wallace SS, Doublié S.

J Mol Biol. 2011 Sep 9;412(1):22-34. doi: 10.1016/j.jmb.2011.07.007. Epub 2011 Jul 18.

28.

Expression of NF-κB-related proteins and their modulation during TNF-α-provoked apoptosis in prostate cancer cells.

Rodríguez-Berriguete G, Fraile B, Paniagua R, Aller P, Royuela M.

Prostate. 2012 Jan;72(1):40-50. doi: 10.1002/pros.21404. Epub 2011 Apr 25.

PMID:
21520161
29.

5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylases.

Le Bihan YV, Angeles Izquierdo M, Coste F, Aller P, Culard F, Gehrke TH, Essalhi K, Carell T, Castaing B.

Nucleic Acids Res. 2011 Aug;39(14):6277-90. doi: 10.1093/nar/gkr215. Epub 2011 Apr 12.

30.

Development of chromanes as novel inhibitors of the uncoupling proteins.

Rial E, Rodríguez-Sánchez L, Aller P, Guisado A, Mar González-Barroso M, Gallardo-Vara E, Redondo-Horcajo M, Castellanos E, Fernández de la Pradilla R, Viso A.

Chem Biol. 2011 Feb 25;18(2):264-74. doi: 10.1016/j.chembiol.2010.12.012.

31.

Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines.

Sánchez Y, Simón GP, Calviño E, de Blas E, Aller P.

J Pharmacol Exp Ther. 2010 Oct;335(1):114-23. doi: 10.1124/jpet.110.168344. Epub 2010 Jul 6.

PMID:
20605902
32.

Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin.

Aller P, Ye Y, Wallace SS, Burrows CJ, Doublié S.

Biochemistry. 2010 Mar 23;49(11):2502-9. doi: 10.1021/bi902195p.

33.

Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases.

Sánchez Y, Calle C, de Blas E, Aller P.

Chem Biol Interact. 2009 Nov 10;182(1):37-44. doi: 10.1016/j.cbi.2009.08.015. Epub 2009 Aug 29.

PMID:
19720055
34.

Inhibition of p38-MAPK potentiates cisplatin-induced apoptosis via GSH depletion and increases intracellular drug accumulation in growth-arrested kidney tubular epithelial cells.

Rodríguez-García ME, Quiroga AG, Castro J, Ortiz A, Aller P, Mata F.

Toxicol Sci. 2009 Oct;111(2):413-23. doi: 10.1093/toxsci/kfp145. Epub 2009 Jul 3.

PMID:
19578154
35.

Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4) Protein kinase modulation and reactive oxygen species generation.

Sánchez Y, Amrán D, de Blas E, Aller P.

Biochem Pharmacol. 2009 Feb 1;77(3):384-96. doi: 10.1016/j.bcp.2008.10.035. Epub 2008 Nov 6.

PMID:
19038232
37.

Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines.

Ramos AM, Aller P.

Biochem Pharmacol. 2008 May 15;75(10):1912-23. doi: 10.1016/j.bcp.2008.02.007. Epub 2008 Feb 16.

PMID:
18359480
38.

Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways.

Amrán D, Sánchez Y, Fernández C, Ramos AM, de Blas E, Bréard J, Calle C, Aller P.

Biochim Biophys Acta. 2007 Nov;1773(11):1653-63. Epub 2007 Jun 22.

39.

A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol.

Aller P, Rould MA, Hogg M, Wallace SS, Doublié S.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):814-8. Epub 2007 Jan 8.

40.
41.

Transmembrane helix packing of ErbB/Neu receptor in membrane environment: a molecular dynamics study.

Aller P, Garnier N, Genest M.

J Biomol Struct Dyn. 2006 Dec;24(3):209-28.

PMID:
17054379
42.

Trans platinum complexes design: one novel water soluble oxime derivative that contains aliphatic amines in trans configuration.

Quiroga AG, Cubo L, de Blas E, Aller P, Navarro-Ranninger C.

J Inorg Biochem. 2007 Jan;101(1):104-10. Epub 2006 Sep 5.

PMID:
17049609
43.

P38 MAPK protects against TNF-alpha-provoked apoptosis in LNCaP prostatic cancer cells.

Ricote M, García-Tuñón I, Fraile B, Fernández C, Aller P, Paniagua R, Royuela M.

Apoptosis. 2006 Nov;11(11):1969-75.

PMID:
17031491
45.

Regulation of apoptosis/necrosis execution in cadmium-treated human promonocytic cells under different forms of oxidative stress.

Sancho P, Fernández C, Yuste VJ, Amrán D, Ramos AM, de Blas E, Susin SA, Aller P.

Apoptosis. 2006 May;11(5):673-86.

PMID:
16532269
46.
47.
48.

Regulation of cadmium-induced apoptosis by PKCdelta in U937 human promonocytic cells.

Miguel BG, Rodriguez ME, Aller P, Martinez AM, Mata F.

Biochim Biophys Acta. 2005 Apr 15;1743(3):215-22. Epub 2004 Nov 11.

49.
50.

Supplemental Content

Support Center