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Items: 1 to 50 of 228

1.

Voluntary Chronic Heavy Alcohol Consumption in Male Rhesus Macaques Suppresses Cancellous Bone Formation and Increases Bone Marrow Adiposity.

Kahler-Quesada AM, Grant KA, Walter NAR, Newman N, Allen MR, Burr DB, Branscum AJ, Maddalozzo GF, Turner RT, Iwaniec UT.

Alcohol Clin Exp Res. 2019 Sep 26. doi: 10.1111/acer.14202. [Epub ahead of print]

PMID:
31557335
2.

Age- and sex-dependent role of osteocytic pannexin1 on bone and muscle mass and strength.

Aguilar-Perez A, Pacheco-Costa R, Atkinson EG, Deosthale P, Davis HM, Essex AL, Dilley JE, Gomez L, Rupert JE, Zimmers TA, Thompson RJ, Allen MR, Plotkin LI.

Sci Rep. 2019 Sep 25;9(1):13903. doi: 10.1038/s41598-019-50444-1.

3.

Osteocytic miR21 deficiency improves bone strength independent of sex despite having sex divergent effects on osteocyte viability and bone turnover.

Davis HM, Deosthale PJ, Pacheco-Costa R, Essex AL, Atkinson EG, Aref MW, Dilley JE, Bellido T, Ivan M, Allen MR, Plotkin LI.

FEBS J. 2019 Sep 18. doi: 10.1111/febs.15066. [Epub ahead of print]

PMID:
31532878
4.

Voluntary Wheel Running Has Beneficial Effects in a Rat Model of CKD-Mineral Bone Disorder (CKD-MBD).

Avin KG, Allen MR, Chen NX, Srinivasan S, O'Neill KD, Troutman AD, Mast G, Swallow EA, Brown MB, Wallace JM, Zimmers TA, Warden SJ, Moe SM.

J Am Soc Nephrol. 2019 Oct;30(10):1898-1909. doi: 10.1681/ASN.2019040349. Epub 2019 Sep 9.

PMID:
31501355
5.

Skeletal levels of bisphosphonate in the setting of chronic kidney disease are independent of remodeling rate and lower with fractionated dosing.

Swallow EA, Aref MW, Metzger CE, Sacks S, Lehmkuhler DR, Chen N, Hammond MA, Territo PR, Nickolas TL, Moe SM, Allen MR.

Bone. 2019 Oct;127:419-426. doi: 10.1016/j.bone.2019.07.007. Epub 2019 Jul 9.

PMID:
31299384
6.

Zoledronate and Raloxifene combination therapy enhances material and mechanical properties of diseased mouse bone.

Powell KM, Skaggs C, Pulliam A, Berman A, Allen MR, Wallace JM.

Bone. 2019 Oct;127:199-206. doi: 10.1016/j.bone.2019.06.018. Epub 2019 Jun 21.

PMID:
31233931
7.

Positive impact of low-dose, high-energy radiation on bone in partial- and/or full-weightbearing mice.

Bokhari RS, Metzger CE, Black JM, Franklin KA, Boudreaux RD, Allen MR, Macias BR, Hogan HA, Braby LA, Bloomfield SA.

NPJ Microgravity. 2019 Jun 4;5:13. doi: 10.1038/s41526-019-0074-3. eCollection 2019.

8.

The influence of temperature on the emissions of organophosphate ester flame retardants from polyisocyanurate foam: Measurement and modeling.

Liang Y, Liu X, Allen MR.

Chemosphere. 2019 Oct;233:347-354. doi: 10.1016/j.chemosphere.2019.05.289. Epub 2019 May 31.

PMID:
31176897
9.

Effect of ovariectomy on the progression of chronic kidney disease-mineral bone disorder (CKD-MBD) in female Cy/+ rats.

Vorland CJ, Lachcik PJ, Swallow EA, Metzger CE, Allen MR, Chen NX, Moe SM, Hill Gallant KM.

Sci Rep. 2019 May 28;9(1):7936. doi: 10.1038/s41598-019-44415-9.

10.

Parathyroid suppression therapy normalizes chronic kidney disease-induced elevations in cortical bone vascular perfusion: a pilot study.

Aref MW, Swallow EA, Metzger CE, Chen N, Moe SM, Allen MR.

Osteoporos Int. 2019 Aug;30(8):1693-1698. doi: 10.1007/s00198-019-04974-z. Epub 2019 May 8.

PMID:
31069439
11.

Time course of rapid bone loss and cortical porosity formation observed by longitudinal μCT in a rat model of CKD.

McNerny EMB, Buening DT, Aref MW, Chen NX, Moe SM, Allen MR.

Bone. 2019 Aug;125:16-24. doi: 10.1016/j.bone.2019.05.002. Epub 2019 May 3.

PMID:
31059864
12.

Short-term pharmacologic RAGE inhibition differentially affects bone and skeletal muscle in middle-aged mice.

Davis HM, Essex AL, Valdez S, Deosthale PJ, Aref MW, Allen MR, Bonetto A, Plotkin LI.

Bone. 2019 Jul;124:89-102. doi: 10.1016/j.bone.2019.04.012. Epub 2019 Apr 24.

PMID:
31028960
13.

Increased FGF23 protects against detrimental cardio-renal consequences during elevated blood phosphate in CKD.

Clinkenbeard EL, Noonan ML, Thomas JC, Ni P, Hum JM, Aref M, Swallow EA, Moe SM, Allen MR, White KE.

JCI Insight. 2019 Feb 21;4(4). pii: 123817. doi: 10.1172/jci.insight.123817. eCollection 2019 Feb 21.

14.

Loss of Nmp4 optimizes osteogenic metabolism and secretion to enhance bone quality.

Shao Y, Wichern E, Childress PJ, Adaway M, Misra J, Klunk A, Burr DB, Wek RC, Mosley AL, Liu Y, Robling AG, Brustovetsky N, Hamilton J, Jacobs K, Vashishth D, Stayrook KR, Allen MR, Wallace JM, Bidwell JP.

Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E749-E772. doi: 10.1152/ajpendo.00343.2018. Epub 2019 Jan 15.

PMID:
30645175
15.

Mechanics of linear microcracking in trabecular bone.

Hammond MA, Wallace JM, Allen MR, Siegmund T.

J Biomech. 2019 Jan 23;83:34-42. doi: 10.1016/j.jbiomech.2018.11.018. Epub 2018 Nov 16.

PMID:
30473136
16.

Effects of treadmill running in a rat model of chronic kidney disease.

Organ JM, Allen MR, Myers-White A, Elkhatib W, O'Neill KD, Chen NX, Moe SM, Avin KG.

Biochem Biophys Rep. 2018 Sep 14;16:19-23. doi: 10.1016/j.bbrep.2018.09.001. eCollection 2018 Dec.

17.

Skeletal vascular perfusion is altered in chronic kidney disease.

Aref MW, Swallow EA, Chen NX, Moe SM, Allen MR.

Bone Rep. 2018 May 4;8:215-220. doi: 10.1016/j.bonr.2018.05.001. eCollection 2018 Jun.

18.

Skeletal accumulation of fluorescently tagged zoledronate is higher in animals with early stage chronic kidney disease.

Swallow EA, Aref MW, Chen N, Byiringiro I, Hammond MA, McCarthy BP, Territo PR, Kamocka MM, Winfree S, Dunn KW, Moe SM, Allen MR.

Osteoporos Int. 2018 Sep;29(9):2139-2146. doi: 10.1007/s00198-018-4589-3. Epub 2018 Jun 11.

19.

Reversal of loss of bone mass in old mice treated with mefloquine.

Pacheco-Costa R, Davis HM, Atkinson EG, Dilley JE, Byiringiro I, Aref MW, Allen MR, Bellido T, Plotkin LI.

Bone. 2018 Sep;114:22-31. doi: 10.1016/j.bone.2018.06.002. Epub 2018 Jun 5.

20.

The many possible climates from the Paris Agreement's aim of 1.5 °C warming.

Seneviratne SI, Rogelj J, Séférian R, Wartenburger R, Allen MR, Cain M, Millar RJ, Ebi KL, Ellis N, Hoegh-Guldberg O, Payne AJ, Schleussner CF, Tschakert P, Warren RF.

Nature. 2018 Jun;558(7708):41-49. doi: 10.1038/s41586-018-0181-4. Epub 2018 Jun 6.

PMID:
29875489
21.

Measurements of Parameters Controlling the Emissions of Organophosphate Flame Retardants in Indoor Environments.

Liang Y, Liu X, Allen MR.

Environ Sci Technol. 2018 May 15;52(10):5821-5829. doi: 10.1021/acs.est.8b00224. Epub 2018 Apr 27.

22.

The myriad challenges of the Paris Agreement.

Mitchell D, Allen MR, Hall JW, Muller B, Rajamani L, Le Quéré C.

Philos Trans A Math Phys Eng Sci. 2018 May 13;376(2119). pii: 20180066. doi: 10.1098/rsta.2018.0066.

23.

Uncertain impacts on economic growth when stabilizing global temperatures at 1.5°C or 2°C warming.

Pretis F, Schwarz M, Tang K, Haustein K, Allen MR.

Philos Trans A Math Phys Eng Sci. 2018 May 13;376(2119). pii: 20160460. doi: 10.1098/rsta.2016.0460.

24.

Recent Advances in Understanding Bisphosphonate Effects on Bone Mechanical Properties.

Allen MR.

Curr Osteoporos Rep. 2018 Apr;16(2):198-204. doi: 10.1007/s11914-018-0430-3. Review.

25.

Inhibition of CaMKK2 Enhances Fracture Healing by Stimulating Indian Hedgehog Signaling and Accelerating Endochondral Ossification.

Williams JN, Kambrath AV, Patel RB, Kang KS, Mével E, Li Y, Cheng YH, Pucylowski AJ, Hassert MA, Voor MJ, Kacena MA, Thompson WR, Warden SJ, Burr DB, Allen MR, Robling AG, Sankar U.

J Bone Miner Res. 2018 May;33(5):930-944. doi: 10.1002/jbmr.3379. Epub 2018 Feb 5.

26.

Measuring and modeling surface sorption dynamics of organophosphate flame retardants on impervious surfaces.

Liang Y, Liu X, Allen MR.

Chemosphere. 2018 Feb;193:754-762. doi: 10.1016/j.chemosphere.2017.11.080. Epub 2017 Nov 17.

27.

Incorporating tissue anisotropy and heterogeneity in finite element models of trabecular bone altered predicted local stress distributions.

Hammond MA, Wallace JM, Allen MR, Siegmund T.

Biomech Model Mechanobiol. 2018 Apr;17(2):605-614. doi: 10.1007/s10237-017-0981-8. Epub 2017 Nov 14.

PMID:
29139053
28.

A real-time Global Warming Index.

Haustein K, Allen MR, Forster PM, Otto FEL, Mitchell DM, Matthews HD, Frame DJ.

Sci Rep. 2017 Nov 13;7(1):15417. doi: 10.1038/s41598-017-14828-5.

29.

Preclinical Models for Skeletal Research: How Commonly Used Species Mimic (or Don't) Aspects of Human Bone.

Allen MR.

Toxicol Pathol. 2017 Oct;45(7):851-854. doi: 10.1177/0192623317733925. Epub 2017 Sep 25. Review.

PMID:
28946796
30.

Corrigendum to "Even with rehydration, preservation in ethanol influences the mechanical properties of bone and how bone responds to experimental manipulation" [Bone 97 (2017) 49-53].

Vesper EO, Hammond MA, Allen MR, Wallace JM.

Bone. 2017 Dec;105:218. doi: 10.1016/j.bone.2017.08.033. Epub 2017 Sep 18. No abstract available.

PMID:
28931494
31.

The fracture toughness of small animal cortical bone measured using arc-shaped tension specimens: Effects of bisphosphonate and deproteinization treatments.

Hunckler MD, Chu ED, Baumann AP, Curtis TE, Ravosa MJ, Allen MR, Roeder RK.

Bone. 2017 Dec;105:67-74. doi: 10.1016/j.bone.2017.08.015. Epub 2017 Aug 18.

PMID:
28826844
32.

Effects of combination treatment with alendronate and raloxifene on skeletal properties in a beagle dog model.

Allen MR, McNerny E, Aref M, Organ JM, Newman CL, McGowan B, Jang T, Burr DB, Brown DM, Hammond M, Territo PR, Lin C, Persohn S, Jiang L, Riley AA, McCarthy BP, Hutchins GD, Wallace JM.

PLoS One. 2017 Aug 9;12(8):e0181750. doi: 10.1371/journal.pone.0181750. eCollection 2017.

33.

Exposure to Low-Dose X-Ray Radiation Alters Bone Progenitor Cells and Bone Microarchitecture.

Lima F, Swift JM, Greene ES, Allen MR, Cunningham DA, Braby LA, Bloomfield SA.

Radiat Res. 2017 Oct;188(4):433-442. doi: 10.1667/RR14414.1. Epub 2017 Aug 3.

PMID:
28771086
34.

Rad GTPase is essential for the regulation of bone density and bone marrow adipose tissue in mice.

Withers CN, Brown DM, Byiringiro I, Allen MR, Condon KW, Satin J, Andres DA.

Bone. 2017 Oct;103:270-280. doi: 10.1016/j.bone.2017.07.018. Epub 2017 Jul 18.

PMID:
28732776
35.

Effects of daily restraint with and without injections on skeletal properties in C57BL/6NHsd mice.

Larsen RA, Peveler JL, Klutzke JB, Hickman DL, Aref MW, Wallace JM, Brown DM, Allen MR.

Lab Anim (NY). 2017 Jun 23;46(7):299-301. doi: 10.1038/laban.1295. No abstract available.

36.

Improving Combination Osteoporosis Therapy in a Preclinical Model of Heightened Osteoanabolism.

Shao Y, Hernandez-Buquer S, Childress P, Stayrook KR, Alvarez MB, Davis H, Plotkin LI, He Y, Condon KW, Burr DB, Warden SJ, Robling AG, Yang FC, Wek RC, Allen MR, Bidwell JP.

Endocrinology. 2017 Sep 1;158(9):2722-2740. doi: 10.1210/en.2017-00355.

37.

Assessment of regional bone tissue perfusion in rats using fluorescent microspheres.

Aref MW, Akans E, Allen MR.

Bone Rep. 2017 Apr 26;6:140-144. doi: 10.1016/j.bonr.2017.04.004. eCollection 2017 Jun.

38.

What Animal Models Have Taught Us About the Safety and Efficacy of Bisphosphonates in Chronic Kidney Disease.

Allen MR, Aref MW.

Curr Osteoporos Rep. 2017 Jun;15(3):171-177. doi: 10.1007/s11914-017-0361-4. Review.

39.

Raloxifene Improves Bone Mechanical Properties in Mice Previously Treated with Zoledronate.

Meixner CN, Aref MW, Gupta A, McNerny EMB, Brown D, Wallace JM, Allen MR.

Calcif Tissue Int. 2017 Jul;101(1):75-81. doi: 10.1007/s00223-017-0257-4. Epub 2017 Feb 28.

40.

Even with rehydration, preservation in ethanol influences the mechanical properties of bone and how bone responds to experimental manipulation.

Vesper EO, Hammond MA, Allen MR, Wallace JM.

Bone. 2017 Apr;97:49-53. doi: 10.1016/j.bone.2017.01.001. Epub 2017 Jan 3. Erratum in: Bone. 2017 Dec;105:218.

41.

PTHrP-Derived Peptides Restore Bone Mass and Strength in Diabetic Mice: Additive Effect of Mechanical Loading.

Maycas M, McAndrews KA, Sato AY, Pellegrini GG, Brown DM, Allen MR, Plotkin LI, Gortazar AR, Esbrit P, Bellido T.

J Bone Miner Res. 2017 Mar;32(3):486-497. doi: 10.1002/jbmr.3007. Epub 2016 Oct 24.

42.

Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin.

Sato AY, Cregor M, Delgado-Calle J, Condon KW, Allen MR, Peacock M, Plotkin LI, Bellido T.

J Bone Miner Res. 2016 Oct;31(10):1791-1802. doi: 10.1002/jbmr.2869. Epub 2016 Jun 5.

43.

Assessing the inter- and intra-animal variability of in vivo OsteoProbe skeletal measures in untreated dogs.

McNerny EM, Organ JM, Wallace JM, Newman CL, Brown DM, Allen MR.

Bone Rep. 2016 Dec;5:192-198. Epub 2016 Aug 8.

44.

Corrigendum to "Structural features underlying raloxifene's biophysical interaction with bone matrix" [Bioorg. Med. Chem. 24 (2016) 759-767].

Bivi N, Hu H, Chavali B, Chalmers MJ, Reutter CT, Durst GL, Riley A, Sato M, Allen MR, Burr DB, Dodge JA.

Bioorg Med Chem. 2016 Sep 15;24(18):4516. doi: 10.1016/j.bmc.2016.07.014. Epub 2016 Jul 14. No abstract available.

PMID:
27544045
45.

Simulating the Lunar Environment: Partial Weightbearing and High-LET Radiation-Induce Bone Loss and Increase Sclerostin-Positive Osteocytes.

Macias BR, Lima F, Swift JM, Shirazi-Fard Y, Greene ES, Allen MR, Fluckey J, Hogan HA, Braby L, Wang S, Bloomfield SA.

Radiat Res. 2016 Sep;186(3):254-63. doi: 10.1667/RR13579.1. Epub 2016 Aug 18.

PMID:
27538114
46.

Skeletal Muscle Regeneration and Oxidative Stress Are Altered in Chronic Kidney Disease.

Avin KG, Chen NX, Organ JM, Zarse C, O'Neill K, Conway RG, Konrad RJ, Bacallao RL, Allen MR, Moe SM.

PLoS One. 2016 Aug 3;11(8):e0159411. doi: 10.1371/journal.pone.0159411. eCollection 2016.

47.

Zoledronate treatment has different effects in mouse strains with contrasting baseline bone mechanical phenotypes.

Aref MW, McNerny EM, Brown D, Jepsen KJ, Allen MR.

Osteoporos Int. 2016 Dec;27(12):3637-3643. Epub 2016 Jul 20.

48.

Reference point indentation is insufficient for detecting alterations in traditional mechanical properties of bone under common experimental conditions.

Krege JB, Aref MW, McNerny E, Wallace JM, Organ JM, Allen MR.

Bone. 2016 Jun;87:97-101. doi: 10.1016/j.bone.2016.04.002. Epub 2016 Apr 9.

49.

Calcitriol Suppression of Parathyroid Hormone Fails to Improve Skeletal Properties in an Animal Model of Chronic Kidney Disease.

Newman CL, Tian N, Hammond MA, Wallace JM, Brown DM, Chen NX, Moe SM, Allen MR.

Am J Nephrol. 2016;43(1):20-31. doi: 10.1159/000444423. Epub 2016 Feb 17.

50.

Corrigendum to "The resistance of cortical bone tissue to failure under cyclic loading is reduced with alendronate"[Bone 64 (2014) 57-64].

Bajaj D, Geissler JR, Allen MR, Burr DB, Fritton JC.

Bone. 2016 Feb;83:283. doi: 10.1016/j.bone.2015.03.009. Epub 2015 Mar 27. No abstract available.

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