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Items: 8


Spatiotemporal Loss of NF1 in Schwann Cell Lineage Leads to Different Types of Cutaneous Neurofibroma Susceptible to Modification by the Hippo Pathway.

Chen Z, Mo J, Brosseau JP, Shipman T, Wang Y, Liao CP, Cooper JM, Allaway RJ, Gosline SJC, Guinney J, Carroll TJ, Le LQ.

Cancer Discov. 2019 Jan;9(1):114-129. doi: 10.1158/2159-8290.CD-18-0151. Epub 2018 Oct 22.


Probing the chemical-biological relationship space with the Drug Target Explorer.

Allaway RJ, La Rosa S, Guinney J, Gosline SJC.

J Cheminform. 2018 Aug 20;10(1):41. doi: 10.1186/s13321-018-0297-4.


Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2.

Synodos for NF2 Consortium, Allaway R, Angus SP, Beauchamp RL, Blakeley JO, Bott M, Burns SS, Carlstedt A, Chang LS, Chen X, Clapp DW, Desouza PA, Erdin S, Fernandez-Valle C, Guinney J, Gusella JF, Haggarty SJ, Johnson GL, La Rosa S, Morrison H, Petrilli AM, Plotkin SR, Pratap A, Ramesh V, Sciaky N, Stemmer-Rachamimov A, Stuhlmiller TJ, Talkowski ME, Welling DB, Yates CW, Zawistowski JS, Zhao WN.

PLoS One. 2018 Jun 13;13(6):e0197350. doi: 10.1371/journal.pone.0197350. eCollection 2018.


Cutaneous neurofibromas in the genomics era: current understanding and open questions.

Allaway RJ, Gosline SJC, La Rosa S, Knight P, Bakker A, Guinney J, Le LQ.

Br J Cancer. 2018 Jun;118(12):1539-1548. doi: 10.1038/s41416-018-0073-2. Epub 2018 Apr 26. Review.


Exploiting mitochondrial and metabolic homeostasis as a vulnerability in NF1 deficient cells.

Allaway RJ, Wood MD, Downey SL, Bouley SJ, Traphagen NA, Wells JD, Batra J, Melancon SN, Ringelberg C, Seibel W, Ratner N, Sanchez Y.

Oncotarget. 2017 Jul 18;9(22):15860-15875. doi: 10.18632/oncotarget.19335. eCollection 2018 Mar 23.


A machine learning classifier trained on cancer transcriptomes detects NF1 inactivation signal in glioblastoma.

Way GP, Allaway RJ, Bouley SJ, Fadul CE, Sanchez Y, Greene CS.

BMC Genomics. 2017 Feb 6;18(1):127. doi: 10.1186/s12864-017-3519-7.


Genomic characterization of patient-derived xenograft models established from fine needle aspirate biopsies of a primary pancreatic ductal adenocarcinoma and from patient-matched metastatic sites.

Allaway RJ, Fischer DA, de Abreu FB, Gardner TB, Gordon SR, Barth RJ, Colacchio TA, Wood M, Kacsoh BZ, Bouley SJ, Cui J, Hamilton J, Choi JA, Lange JT, Peterson JD, Padmanabhan V, Tomlinson CR, Tsongalis GJ, Suriawinata AA, Greene CS, Sanchez Y, Smith KD.

Oncotarget. 2016 Mar 29;7(13):17087-102. doi: 10.18632/oncotarget.7718.


Gold nanoparticle trafficking of typically excluded compounds across the cell membrane in JB6 Cl 41-5a cells causes assay interference.

Keene AM, Allaway RJ, Sadrieh N, Tyner KM.

Nanotoxicology. 2011 Dec;5(4):469-78. doi: 10.3109/17435390.2010.533792. Epub 2010 Nov 19.


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