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Items: 34

1.

Elevated temperature triggers human respiratory syncytial virus F protein six-helix bundle formation.

Yunus AS, Jackson TP, Crisafi K, Burimski I, Kilgore NR, Zoumplis D, Allaway GP, Wild CT, Salzwedel K.

Virology. 2010 Jan 20;396(2):226-37. doi: 10.1016/j.virol.2009.10.040. Epub 2009 Nov 18.

2.

Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents.

Qian K, Yu D, Chen CH, Huang L, Morris-Natschke SL, Nitz TJ, Salzwedel K, Reddick M, Allaway GP, Lee KH.

J Med Chem. 2009 May 28;52(10):3248-58. doi: 10.1021/jm900136j.

3.

Susceptibility of human immunodeficiency virus type 1 to the maturation inhibitor bevirimat is modulated by baseline polymorphisms in Gag spacer peptide 1.

Van Baelen K, Salzwedel K, Rondelez E, Van Eygen V, De Vos S, Verheyen A, Steegen K, Verlinden Y, Allaway GP, Stuyver LJ.

Antimicrob Agents Chemother. 2009 May;53(5):2185-8. doi: 10.1128/AAC.01650-08. Epub 2009 Feb 17.

4.

Bevirimat: a novel maturation inhibitor for the treatment of HIV-1 infection.

Martin DE, Salzwedel K, Allaway GP.

Antivir Chem Chemother. 2008;19(3):107-13. Review.

PMID:
19024627
5.

Potent activity of the HIV-1 maturation inhibitor bevirimat in SCID-hu Thy/Liv mice.

Stoddart CA, Joshi P, Sloan B, Bare JC, Smith PC, Allaway GP, Wild CT, Martin DE.

PLoS One. 2007 Nov 28;2(11):e1251.

6.

Anti-AIDS agents 73: structure-activity relationship study and asymmetric synthesis of 3-O-monomethylsuccinyl-betulinic acid derivatives.

Qian K, Nakagawa-Goto K, Yu D, Morris-Natschke SL, Nitz TJ, Kilgore N, Allaway GP, Lee KH.

Bioorg Med Chem Lett. 2007 Dec 1;17(23):6553-7.

7.

Phase I and II study of the safety, virologic effect, and pharmacokinetics/pharmacodynamics of single-dose 3-o-(3',3'-dimethylsuccinyl)betulinic acid (bevirimat) against human immunodeficiency virus infection.

Smith PF, Ogundele A, Forrest A, Wilton J, Salzwedel K, Doto J, Allaway GP, Martin DE.

Antimicrob Agents Chemother. 2007 Oct;51(10):3574-81. Epub 2007 Jul 16.

8.

Determinants of activity of the HIV-1 maturation inhibitor PA-457.

Li F, Zoumplis D, Matallana C, Kilgore NR, Reddick M, Yunus AS, Adamson CS, Salzwedel K, Martin DE, Allaway GP, Freed EO, Wild CT.

Virology. 2006 Dec 5-20;356(1-2):217-24. Epub 2006 Aug 22.

9.

The discovery of a class of novel HIV-1 maturation inhibitors and their potential in the therapy of HIV.

Yu D, Wild CT, Martin DE, Morris-Natschke SL, Chen CH, Allaway GP, Lee KH.

Expert Opin Investig Drugs. 2005 Jun;14(6):681-93. Review.

PMID:
16004596
10.

3-O-Glutaryl-dihydrobetulin and related monoacyl derivatives as potent anti-HIV agents.

Kashiwada Y, Sekiya M, Ikeshiro Y, Fujioka T, Kilgore NR, Wild CT, Allaway GP, Lee KH.

Bioorg Med Chem Lett. 2004 Dec 6;14(23):5851-3.

PMID:
15501054
11.

PA-457: a potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing.

Li F, Goila-Gaur R, Salzwedel K, Kilgore NR, Reddick M, Matallana C, Castillo A, Zoumplis D, Martin DE, Orenstein JM, Allaway GP, Freed EO, Wild CT.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13555-60. Epub 2003 Oct 22.

12.
13.

CD4-immunoglobulin G2 protects Hu-PBL-SCID mice against challenge by primary human immunodeficiency virus type 1 isolates.

Gauduin MC, Allaway GP, Olson WC, Weir R, Maddon PJ, Koup RA.

J Virol. 1998 Apr;72(4):3475-8.

14.

AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor.

Donzella GA, Schols D, Lin SW, Esté JA, Nagashima KA, Maddon PJ, Allaway GP, Sakmar TP, Henson G, De Clercq E, Moore JP.

Nat Med. 1998 Jan;4(1):72-7.

PMID:
9427609
15.

Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry.

Dragic T, Trkola A, Lin SW, Nagashima KA, Kajumo F, Zhao L, Olson WC, Wu L, Mackay CR, Allaway GP, Sakmar TP, Moore JP, Maddon PJ.

J Virol. 1998 Jan;72(1):279-85.

16.

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

Trkola A, Dragic T, Arthos J, Binley JM, Olson WC, Allaway GP, Cheng-Mayer C, Robinson J, Maddon PJ, Moore JP.

Nature. 1996 Nov 14;384(6605):184-7.

PMID:
8906796
17.

Human immunodeficiency virus type 1 membrane fusion mediated by a laboratory-adapted strain and a primary isolate analyzed by resonance energy transfer.

Litwin V, Nagashima KA, Ryder AM, Chang CH, Carver JM, Olson WC, Alizon M, Hasel KW, Maddon PJ, Allaway GP.

J Virol. 1996 Sep;70(9):6437-41.

18.

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5.

Dragic T, Litwin V, Allaway GP, Martin SR, Huang Y, Nagashima KA, Cayanan C, Maddon PJ, Koup RA, Moore JP, Paxton WA.

Nature. 1996 Jun 20;381(6584):667-73.

PMID:
8649512
19.

Effective ex vivo neutralization of human immunodeficiency virus type 1 in plasma by recombinant immunoglobulin molecules.

Gauduin MC, Allaway GP, Maddon PJ, Barbas CF 3rd, Burton DR, Koup RA.

J Virol. 1996 Apr;70(4):2586-92.

20.

Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG.

Trkola A, Pomales AB, Yuan H, Korber B, Maddon PJ, Allaway GP, Katinger H, Barbas CF 3rd, Burton DR, Ho DD, et al.

J Virol. 1995 Nov;69(11):6609-17.

21.

Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates.

Allaway GP, Davis-Bruno KL, Beaudry GA, Garcia EB, Wong EL, Ryder AM, Hasel KW, Gauduin MC, Koup RA, McDougal JS, et al.

AIDS Res Hum Retroviruses. 1995 May;11(5):533-9.

PMID:
7576908
22.
23.

Synergistic inhibition of HIV-1 envelope-mediated cell fusion by CD4-based molecules in combination with antibodies to gp120 or gp41.

Allaway GP, Ryder AM, Beaudry GA, Maddon PJ.

AIDS Res Hum Retroviruses. 1993 Jul;9(7):581-7.

PMID:
8369162
24.

Prokaryotic expression of the thyrotropin receptor and identification of an immunogenic region of the protein using synthetic peptides.

Takai O, Desai RK, Seetharamaiah GS, Jones CA, Allaway GP, Akamizu T, Kohn LD, Prabhakar BS.

Biochem Biophys Res Commun. 1991 Aug 30;179(1):319-26.

PMID:
1883361
25.

Cell surface expression of the 70-kD component of Ku, a DNA-binding nuclear autoantigen.

Prabhakar BS, Allaway GP, Srinivasappa J, Notkins AL.

J Clin Invest. 1990 Oct;86(4):1301-5.

26.

Characterization of the 70KDA component of the human Ku autoantigen expressed in insect cell nuclei using a recombinant baculovirus vector.

Allaway GP, Vivino AA, Kohn LD, Notkins AL, Prabhakar BS.

Biochem Biophys Res Commun. 1990 Apr 30;168(2):747-55.

PMID:
1692216
27.

A potential for mutual regulation of proopiomelanocortin gene and Epstein-Barr virus expression in human lymphocytes.

Oates EL, Allaway GP, Prabhakar BS.

Ann N Y Acad Sci. 1990;594:60-5. No abstract available.

PMID:
2165763
28.

Human lymphocytes produce pro-opiomelanocortin gene-related transcripts. Effects of lymphotropic viruses.

Oates EL, Allaway GP, Armstrong GR, Boyajian RA, Kehrl JH, Prabhakar BS.

J Biol Chem. 1988 Jul 25;263(21):10041-4.

29.

Spontaneously proliferating human B lymphocytes make autoantibodies.

Allaway GP, Srinivasappa J, Miller FW, Prabhakar BS, Notkins AL.

J Infect Dis. 1988 May;157(5):968-72.

PMID:
2834468
31.

Aggregation of encephalomyocarditis virus induced by radio-iodination.

Burness AT, Pardoe IU, Allaway GP.

J Virol Methods. 1986 Sep;14(2):167-76.

PMID:
3021803
32.

Site of attachment of encephalomyocarditis virus on human erythrocytes.

Allaway GP, Burness AT.

J Virol. 1986 Sep;59(3):768-70.

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