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Items: 21

1.

Atypical APC/C-dependent degradation of Mcl-1 provides an apoptotic timer during mitotic arrest.

Allan LA, Skowyra A, Rogers KI, Zeller D, Clarke PR.

EMBO J. 2018 Jul 9. pii: e96831. doi: 10.15252/embj.201796831. [Epub ahead of print]

2.

USP9X Limits Mitotic Checkpoint Complex Turnover to Strengthen the Spindle Assembly Checkpoint and Guard against Chromosomal Instability.

Skowyra A, Allan LA, Saurin AT, Clarke PR.

Cell Rep. 2018 Apr 17;23(3):852-865. doi: 10.1016/j.celrep.2018.03.100.

3.

Phosphorylation of XIAP by CDK1-cyclin-B1 controls mitotic cell death.

Hou Y, Allan LA, Clarke PR.

J Cell Sci. 2017 Jan 15;130(2):502-511. doi: 10.1242/jcs.192310. Epub 2016 Dec 7.

4.

Prolonged mitotic arrest induces a caspase-dependent DNA damage response at telomeres that determines cell survival.

Hain KO, Colin DJ, Rastogi S, Allan LA, Clarke PR.

Sci Rep. 2016 May 27;6:26766. doi: 10.1038/srep26766.

5.

A test of the universal applicability of a commonly used principle of hoof balance.

Caldwell MN, Allan LA, Pinchbeck GL, Clegg PD, Kissick KE, Milner PI.

Vet J. 2016 Jan;207:169-176. doi: 10.1016/j.tvjl.2015.10.003. Epub 2015 Oct 13.

PMID:
26639831
6.

Cellular responses to a prolonged delay in mitosis are determined by a DNA damage response controlled by Bcl-2 family proteins.

Colin DJ, Hain KO, Allan LA, Clarke PR.

Open Biol. 2015 Mar;5(3):140156. doi: 10.1098/rsob.140156.

7.

Destruction's our delight: controlling apoptosis during mitotic arrest.

Clarke PR, Allan LA.

Cell Cycle. 2010 Oct 15;9(20):4035-6. Epub 2010 Oct 2. No abstract available.

PMID:
20935484
8.

Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest.

Harley ME, Allan LA, Sanderson HS, Clarke PR.

EMBO J. 2010 Jul 21;29(14):2407-20. doi: 10.1038/emboj.2010.112. Epub 2010 Jun 4.

9.

Apoptosis and autophagy: Regulation of caspase-9 by phosphorylation.

Allan LA, Clarke PR.

FEBS J. 2009 Nov;276(21):6063-73. doi: 10.1111/j.1742-4658.2009.07330.x. Epub 2009 Sep 29. Review.

10.

Cell-cycle control in the face of damage--a matter of life or death.

Clarke PR, Allan LA.

Trends Cell Biol. 2009 Mar;19(3):89-98. doi: 10.1016/j.tcb.2008.12.003. Epub 2009 Jan 23. Review.

PMID:
19168356
11.

DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine.

Seifert A, Allan LA, Clarke PR.

FEBS J. 2008 Dec;275(24):6268-80. doi: 10.1111/j.1742-4658.2008.06751.x. Epub 2008 Nov 7.

12.

A mechanism coupling cell division and the control of apoptosis.

Allan LA, Clarke PR.

SEB Exp Biol Ser. 2008;59:257-65.

PMID:
18368928
13.

The docking interaction of caspase-9 with ERK2 provides a mechanism for the selective inhibitory phosphorylation of caspase-9 at threonine 125.

Martin MC, Allan LA, Mancini EJ, Clarke PR.

J Biol Chem. 2008 Feb 15;283(7):3854-65. Epub 2007 Dec 14.

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Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c.

Martin MC, Allan LA, Lickrish M, Sampson C, Morrice N, Clarke PR.

J Biol Chem. 2005 Apr 15;280(15):15449-55. Epub 2005 Feb 9.

17.

Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.

Allan LA, Morrice N, Brady S, Magee G, Pathak S, Clarke PR.

Nat Cell Biol. 2003 Jul;5(7):647-54.

PMID:
12792650
20.

p53 mutation is a common genetic event in ovarian carcinoma.

Milner BJ, Allan LA, Eccles DM, Kitchener HC, Leonard RC, Kelly KF, Parkin DE, Haites NE.

Cancer Res. 1993 May 1;53(9):2128-32.

21.

Linkage studies with 17q and 18q markers in a breast/ovarian cancer family.

Milner BJ, Allan LA, Kelly KF, Cruickshank D, Hall M, Johnston A, Kitchener H, Parkin D, Haites N.

Am J Hum Genet. 1993 Apr;52(4):761-6.

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