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Items: 22

1.

Timed degradation of Mcl-1 controls mitotic cell death.

Clarke PR, Allan LA, Skowyra A.

Mol Cell Oncol. 2018 Oct 11;5(6):e1516450. doi: 10.1080/23723556.2018.1516450. eCollection 2018.

PMID:
30525093
2.

Atypical APC/C-dependent degradation of Mcl-1 provides an apoptotic timer during mitotic arrest.

Allan LA, Skowyra A, Rogers KI, Zeller D, Clarke PR.

EMBO J. 2018 Sep 3;37(17). pii: e96831. doi: 10.15252/embj.201796831. Epub 2018 Jul 9.

3.

USP9X Limits Mitotic Checkpoint Complex Turnover to Strengthen the Spindle Assembly Checkpoint and Guard against Chromosomal Instability.

Skowyra A, Allan LA, Saurin AT, Clarke PR.

Cell Rep. 2018 Apr 17;23(3):852-865. doi: 10.1016/j.celrep.2018.03.100.

4.

Phosphorylation of XIAP by CDK1-cyclin-B1 controls mitotic cell death.

Hou Y, Allan LA, Clarke PR.

J Cell Sci. 2017 Jan 15;130(2):502-511. doi: 10.1242/jcs.192310. Epub 2016 Dec 7.

5.

Prolonged mitotic arrest induces a caspase-dependent DNA damage response at telomeres that determines cell survival.

Hain KO, Colin DJ, Rastogi S, Allan LA, Clarke PR.

Sci Rep. 2016 May 27;6:26766. doi: 10.1038/srep26766.

6.

A test of the universal applicability of a commonly used principle of hoof balance.

Caldwell MN, Allan LA, Pinchbeck GL, Clegg PD, Kissick KE, Milner PI.

Vet J. 2016 Jan;207:169-176. doi: 10.1016/j.tvjl.2015.10.003. Epub 2015 Oct 13.

PMID:
26639831
7.

Cellular responses to a prolonged delay in mitosis are determined by a DNA damage response controlled by Bcl-2 family proteins.

Colin DJ, Hain KO, Allan LA, Clarke PR.

Open Biol. 2015 Mar;5(3):140156. doi: 10.1098/rsob.140156.

8.

Destruction's our delight: controlling apoptosis during mitotic arrest.

Clarke PR, Allan LA.

Cell Cycle. 2010 Oct 15;9(20):4035-6. Epub 2010 Oct 2. No abstract available.

PMID:
20935484
9.

Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest.

Harley ME, Allan LA, Sanderson HS, Clarke PR.

EMBO J. 2010 Jul 21;29(14):2407-20. doi: 10.1038/emboj.2010.112. Epub 2010 Jun 4.

10.

Apoptosis and autophagy: Regulation of caspase-9 by phosphorylation.

Allan LA, Clarke PR.

FEBS J. 2009 Nov;276(21):6063-73. doi: 10.1111/j.1742-4658.2009.07330.x. Epub 2009 Sep 29. Review.

11.

Cell-cycle control in the face of damage--a matter of life or death.

Clarke PR, Allan LA.

Trends Cell Biol. 2009 Mar;19(3):89-98. doi: 10.1016/j.tcb.2008.12.003. Epub 2009 Jan 23. Review.

PMID:
19168356
12.

DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine.

Seifert A, Allan LA, Clarke PR.

FEBS J. 2008 Dec;275(24):6268-80. doi: 10.1111/j.1742-4658.2008.06751.x. Epub 2008 Nov 7.

13.

A mechanism coupling cell division and the control of apoptosis.

Allan LA, Clarke PR.

SEB Exp Biol Ser. 2008;59:257-65.

PMID:
18368928
14.

The docking interaction of caspase-9 with ERK2 provides a mechanism for the selective inhibitory phosphorylation of caspase-9 at threonine 125.

Martin MC, Allan LA, Mancini EJ, Clarke PR.

J Biol Chem. 2008 Feb 15;283(7):3854-65. Epub 2007 Dec 14.

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17.

Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c.

Martin MC, Allan LA, Lickrish M, Sampson C, Morrice N, Clarke PR.

J Biol Chem. 2005 Apr 15;280(15):15449-55. Epub 2005 Feb 9.

18.

Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.

Allan LA, Morrice N, Brady S, Magee G, Pathak S, Clarke PR.

Nat Cell Biol. 2003 Jul;5(7):647-54.

PMID:
12792650
21.

p53 mutation is a common genetic event in ovarian carcinoma.

Milner BJ, Allan LA, Eccles DM, Kitchener HC, Leonard RC, Kelly KF, Parkin DE, Haites NE.

Cancer Res. 1993 May 1;53(9):2128-32.

22.

Linkage studies with 17q and 18q markers in a breast/ovarian cancer family.

Milner BJ, Allan LA, Kelly KF, Cruickshank D, Hall M, Johnston A, Kitchener H, Parkin D, Haites N.

Am J Hum Genet. 1993 Apr;52(4):761-6.

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