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Role of the Microenvironment in Regulating Normal and Cancer Stem Cell Activity: Implications for Breast Cancer Progression and Therapy Response.

Bhat V, Allan AL, Raouf A.

Cancers (Basel). 2019 Aug 24;11(9). pii: E1240. doi: 10.3390/cancers11091240. Review.


Stereotactic ablative radiotherapy for the comprehensive treatment of 4-10 oligometastatic tumors (SABR-COMET-10): study protocol for a randomized phase III trial.

Palma DA, Olson R, Harrow S, Correa RJM, Schneiders F, Haasbeek CJA, Rodrigues GB, Lock M, Yaremko BP, Bauman GS, Ahmad B, Schellenberg D, Liu M, Gaede S, Laba J, Mulroy L, Senthi S, Louie AV, Swaminath A, Chalmers A, Warner A, Slotman BJ, de Gruijl TD, Allan A, Senan S.

BMC Cancer. 2019 Aug 19;19(1):816. doi: 10.1186/s12885-019-5977-6.


Two Y-chromosome-encoded genes determine sex in kiwifruit.

Akagi T, Pilkington SM, Varkonyi-Gasic E, Henry IM, Sugano SS, Sonoda M, Firl A, McNeilage MA, Douglas MJ, Wang T, Rebstock R, Voogd C, Datson P, Allan AC, Beppu K, Kataoka I, Tao R.

Nat Plants. 2019 Aug;5(8):801-809. doi: 10.1038/s41477-019-0489-6. Epub 2019 Aug 5.


Increased Maternal Care Rescues Altered Reinstatement Responding Following Moderate Prenatal Alcohol Exposure.

Olguin SL, Zimmerman A, Zhang H, Allan A, Caldwell KC, Brigman JL.

Alcohol Clin Exp Res. 2019 Sep;43(9):1949-1956. doi: 10.1111/acer.14149. Epub 2019 Aug 14.


AcFT promotes kiwifruit in vitro flowering when overexpressed and Arabidopsis flowering when expressed in the vasculature under its own promoter.

Moss SMA, Wang T, Voogd C, Brian LA, Wu R, Hellens RP, Allan AC, Putterill J, Varkonyi-Gasic E.

Plant Direct. 2018 Jul 10;2(7):e00068. doi: 10.1002/pld3.68. eCollection 2018 Jul.


Microhomologies are prevalent at Cas9-induced larger deletions.

Owens DDG, Caulder A, Frontera V, Harman JR, Allan AJ, Bucakci A, Greder L, Codner GF, Hublitz P, McHugh PJ, Teboul L, de Bruijn MFTR.

Nucleic Acids Res. 2019 Aug 22;47(14):7402-7417. doi: 10.1093/nar/gkz459.


Molecular Mechanisms of Breast Cancer Metastasis to the Lung: Clinical and Experimental Perspectives.

Medeiros B, Allan AL.

Int J Mol Sci. 2019 May 8;20(9). pii: E2272. doi: 10.3390/ijms20092272. Review.


A Phase II Study of PX-866 in Patients With Recurrent or Metastatic Castration-resistant Prostate Cancer: Canadian Cancer Trials Group Study IND205.

Hotte SJ, Chi KN, Joshua AM, Tu D, Macfarlane RJ, Gregg RW, Ruether JD, Basappa NS, Finch D, Salim M, Winquist EW, Torri V, North S, Kollmannsberger C, Ellard SL, Eigl BJ, Tinker A, Allan AL, Beja K, Annala M, Powers J, Wyatt AW, Seymour L; Canadian Cancer Trials Group (formerly NCIC Clinical Trials Group).

Clin Genitourin Cancer. 2019 Jun;17(3):201-208.e1. doi: 10.1016/j.clgc.2019.03.005. Epub 2019 Mar 15.


Indigenous Perspectives and Gene Editing in Aotearoa New Zealand.

Hudson M, Mead ATP, Chagné D, Roskruge N, Morrison S, Wilcox PL, Allan AC.

Front Bioeng Biotechnol. 2019 Apr 11;7:70. doi: 10.3389/fbioe.2019.00070. eCollection 2019.


StMYB44 negatively regulates anthocyanin biosynthesis at high temperatures in tuber flesh of potato.

Liu Y, Lin-Wang K, Espley RV, Wang L, Li Y, Liu Z, Zhou P, Zeng L, Zhang X, Zhang J, Allan AC.

J Exp Bot. 2019 Aug 7;70(15):3809-3824. doi: 10.1093/jxb/erz194.


Hyperhomocysteinemia leads to exacerbation of ischemic brain damage: Role of GluN2A NMDA receptors.

Jindal A, Rajagopal S, Winter L, Miller JW, Jacobsen DW, Brigman J, Allan AM, Paul S, Poddar R.

Neurobiol Dis. 2019 Jul;127:287-302. doi: 10.1016/j.nbd.2019.03.012. Epub 2019 Mar 15.


Maternal circulating miRNAs that predict infant FASD outcomes influence placental maturation.

Tseng AM, Mahnke AH, Wells AB, Salem NA, Allan AM, Roberts VH, Newman N, Walter NA, Kroenke CD, Grant KA, Akison LK, Moritz KM, Chambers CD, Miranda RC; Collaborative Initiative on Fetal Alcohol Spectrum Disorders.

Life Sci Alliance. 2019 Mar 4;2(2). pii: e201800252. doi: 10.26508/lsa.201800252. Print 2019 Apr.


Histone modification and activation by SOC1-like and drought stress-related transcription factors may regulate AcSVP2 expression during kiwifruit winter dormancy.

Wu R, Wang T, Richardson AC, Allan AC, Macknight RC, Varkonyi-Gasic E.

Plant Sci. 2019 Apr;281:242-250. doi: 10.1016/j.plantsci.2018.12.001. Epub 2018 Dec 5.


Patient-specific 3D printed model of biliary ducts with congenital cyst.

Allan A, Kealley C, Squelch A, Wong YH, Yeong CH, Sun Z.

Quant Imaging Med Surg. 2019 Jan;9(1):86-93. doi: 10.21037/qims.2018.12.01.


PbrMYB169 positively regulates lignification of stone cells in pear fruit.

Xue C, Yao JL, Xue YS, Su GQ, Wang L, Lin LK, Allan AC, Zhang SL, Wu J.

J Exp Bot. 2019 Mar 27;70(6):1801-1814. doi: 10.1093/jxb/erz039.


Domestication: Colour and Flavour Joined by a Shared Transcription Factor.

Allan AC.

Curr Biol. 2019 Jan 21;29(2):R57-R59. doi: 10.1016/j.cub.2018.12.005.


Differential regulation of the anthocyanin profile in purple kiwifruit (Actinidia species).

Peng Y, Lin-Wang K, Cooney JM, Wang T, Espley RV, Allan AC.

Hortic Res. 2019 Jan 1;6:3. doi: 10.1038/s41438-018-0076-4. eCollection 2019.


Magnetically Guided Self-Assembled Protein Micelles for Enhanced Delivery of Dasatinib to Human Triple-Negative Breast Cancer Cells.

Sabra SA, Sheweita SA, Haroun M, Ragab D, Eldemellawy MA, Xia Y, Goodale D, Allan AL, Elzoghby AO, Rohani S.

J Pharm Sci. 2019 May;108(5):1713-1725. doi: 10.1016/j.xphs.2018.11.044. Epub 2018 Dec 6.


Performing and interpreting a lumbar puncture.

Perry S, Barnes J, Allan A.

Br J Hosp Med (Lond). 2018 Dec 2;79(12):C183-C187. doi: 10.12968/hmed.2018.79.12.C183. No abstract available. Erratum in: Br J Hosp Med (Lond). 2019 Jan 2;80(1):56.


Re-programming of Pseudomonas syringae pv. actinidiae gene expression during early stages of infection of kiwifruit.

McAtee PA, Brian L, Curran B, van der Linden O, Nieuwenhuizen NJ, Chen X, Henry-Kirk RA, Stroud EA, Nardozza S, Jayaraman J, Rikkerink EHA, Print CG, Allan AC, Templeton MD.

BMC Genomics. 2018 Nov 15;19(1):822. doi: 10.1186/s12864-018-5197-5.


Orange is not just a colour.

Allan AC.

Nat Plants. 2018 Nov;4(11):865-866. doi: 10.1038/s41477-018-0295-6. No abstract available.


Sex-specific deficits in biochemical but not behavioral responses to delay fear conditioning in prenatal alcohol exposure mice.

Caldwell KK, Solomon ER, Smoake JJW, Djatche de Kamgaing CD, Allan AM.

Neurobiol Learn Mem. 2018 Dec;156:1-16. doi: 10.1016/j.nlm.2018.10.002. Epub 2018 Oct 12.


Mutagenesis of kiwifruit CENTRORADIALIS-like genes transforms a climbing woody perennial with long juvenility and axillary flowering into a compact plant with rapid terminal flowering.

Varkonyi-Gasic E, Wang T, Voogd C, Jeon S, Drummond RSM, Gleave AP, Allan AC.

Plant Biotechnol J. 2019 May;17(5):869-880. doi: 10.1111/pbi.13021. Epub 2018 Oct 25.


MYBA From Blueberry (Vaccinium Section Cyanococcus) Is a Subgroup 6 Type R2R3MYB Transcription Factor That Activates Anthocyanin Production.

Plunkett BJ, Espley RV, Dare AP, Warren BAW, Grierson ERP, Cordiner S, Turner JL, Allan AC, Albert NW, Davies KM, Schwinn KE.

Front Plant Sci. 2018 Sep 11;9:1300. doi: 10.3389/fpls.2018.01300. eCollection 2018.


Activator-type R2R3-MYB genes induce a repressor-type R2R3-MYB gene to balance anthocyanin and proanthocyanidin accumulation.

Zhou H, Lin-Wang K, Wang F, Espley RV, Ren F, Zhao J, Ogutu C, He H, Jiang Q, Allan AC, Han Y.

New Phytol. 2019 Mar;221(4):1919-1934. doi: 10.1111/nph.15486. Epub 2018 Oct 13.


A kiwifruit (Actinidia deliciosa) R2R3-MYB transcription factor modulates chlorophyll and carotenoid accumulation.

Ampomah-Dwamena C, Thrimawithana AH, Dejnoprat S, Lewis D, Espley RV, Allan AC.

New Phytol. 2019 Jan;221(1):309-325. doi: 10.1111/nph.15362. Epub 2018 Aug 1.


Linezolid-induced pancytopenia.

Leader R, Hackett J, Allan A, Carter P.

BMJ Case Rep. 2018 Jul 26;2018. pii: bcr-2018-225480. doi: 10.1136/bcr-2018-225480.


MYBs Drive Novel Consumer Traits in Fruits and Vegetables.

Allan AC, Espley RV.

Trends Plant Sci. 2018 Aug;23(8):693-705. doi: 10.1016/j.tplants.2018.06.001. Review.


Characterization of a ripening-related transcription factor FcNAC1 from Fragaria chiloensis fruit.

Carrasco-Orellana C, Stappung Y, Mendez-Yañez A, Allan AC, Espley RV, Plunkett BJ, Moya-Leon MA, Herrera R.

Sci Rep. 2018 Jul 12;8(1):10524. doi: 10.1038/s41598-018-28226-y.


Sex-Dependent Effects of the Histone Deacetylase Inhibitor, Sodium Valproate, on Reversal Learning After Developmental Arsenic Exposure.

Tyler CRS, Smoake JJW, Solomon ER, Villicana E, Caldwell KK, Allan AM.

Front Genet. 2018 Jun 15;9:200. doi: 10.3389/fgene.2018.00200. eCollection 2018.


Assessment of the Validity of Nuclear-Localized Androgen Receptor Splice Variant 7 in Circulating Tumor Cells as a Predictive Biomarker for Castration-Resistant Prostate Cancer.

Scher HI, Graf RP, Schreiber NA, Jayaram A, Winquist E, McLaughlin B, Lu D, Fleisher M, Orr S, Lowes L, Anderson A, Wang Y, Dittamore R, Allan AL, Attard G, Heller G.

JAMA Oncol. 2018 Sep 1;4(9):1179-1186. doi: 10.1001/jamaoncol.2018.1621.


Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants.

Codner GF, Mianné J, Caulder A, Loeffler J, Fell R, King R, Allan AJ, Mackenzie M, Pike FJ, McCabe CV, Christou S, Joynson S, Hutchison M, Stewart ME, Kumar S, Simon MM, Agius L, Anstee QM, Volynski KE, Kullmann DM, Wells S, Teboul L.

BMC Biol. 2018 Jun 21;16(1):70. doi: 10.1186/s12915-018-0530-7.


PbrmiR397a regulates lignification during stone cell development in pear fruit.

Xue C, Yao JL, Qin MF, Zhang MY, Allan AC, Wang DF, Wu J.

Plant Biotechnol J. 2019 Jan;17(1):103-117. doi: 10.1111/pbi.12950. Epub 2018 Jun 21.


Circulating Tumor Cell Analysis in Preclinical Mouse Models of Metastasis.

Kitz J, Lowes LE, Goodale D, Allan AL.

Diagnostics (Basel). 2018 Apr 28;8(2). pii: E30. doi: 10.3390/diagnostics8020030. Review.


Self-assembled amphiphilic zein-lactoferrin micelles for tumor targeted co-delivery of rapamycin and wogonin to breast cancer.

Sabra SA, Elzoghby AO, Sheweita SA, Haroun M, Helmy MW, Eldemellawy MA, Xia Y, Goodale D, Allan AL, Rohani S.

Eur J Pharm Biopharm. 2018 Jul;128:156-169. doi: 10.1016/j.ejpb.2018.04.023. Epub 2018 Apr 22.


Applying the global RCP-SSP-SPA scenario framework at sub-national scale: A multi-scale and participatory scenario approach.

Kebede AS, Nicholls RJ, Allan A, Arto I, Cazcarro I, Fernandes JA, Hill CT, Hutton CW, Kay S, Lázár AN, Macadam I, Palmer M, Suckall N, Tompkins EL, Vincent K, Whitehead PW.

Sci Total Environ. 2018 Sep 1;635:659-672. doi: 10.1016/j.scitotenv.2018.03.368. Epub 2018 Apr 24.


A manually annotated Actinidia chinensis var. chinensis (kiwifruit) genome highlights the challenges associated with draft genomes and gene prediction in plants.

Pilkington SM, Crowhurst R, Hilario E, Nardozza S, Fraser L, Peng Y, Gunaseelan K, Simpson R, Tahir J, Deroles SC, Templeton K, Luo Z, Davy M, Cheng C, McNeilage M, Scaglione D, Liu Y, Zhang Q, Datson P, De Silva N, Gardiner SE, Bassett H, Chagné D, McCallum J, Dzierzon H, Deng C, Wang YY, Barron L, Manako K, Bowen J, Foster TM, Erridge ZA, Tiffin H, Waite CN, Davies KM, Grierson EP, Laing WA, Kirk R, Chen X, Wood M, Montefiori M, Brummell DA, Schwinn KE, Catanach A, Fullerton C, Li D, Meiyalaghan S, Nieuwenhuizen N, Read N, Prakash R, Hunter D, Zhang H, McKenzie M, Knäbel M, Harris A, Allan AC, Gleave A, Chen A, Janssen BJ, Plunkett B, Ampomah-Dwamena C, Voogd C, Leif D, Lafferty D, Souleyre EJF, Varkonyi-Gasic E, Gambi F, Hanley J, Yao JL, Cheung J, David KM, Warren B, Marsh K, Snowden KC, Lin-Wang K, Brian L, Martinez-Sanchez M, Wang M, Ileperuma N, Macnee N, Campin R, McAtee P, Drummond RSM, Espley RV, Ireland HS, Wu R, Atkinson RG, Karunairetnam S, Bulley S, Chunkath S, Hanley Z, Storey R, Thrimawithana AH, Thomson S, David C, Testolin R, Huang H, Hellens RP, Schaffer RJ.

BMC Genomics. 2018 Apr 16;19(1):257. doi: 10.1186/s12864-018-4656-3.


Discovery of {4-[4,9-bis(ethyloxy)-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl]-2-fluorophenyl}acetic acid (GSK726701A), a novel EP4 receptor partial agonist for the treatment of pain.

Healy MP, Allan AC, Bailey K, Billinton A, Chessell IP, Clayton NM, Giblin GMP, Kay MA, Khaznadar T, Michel AD, Naylor A, Price H, Spalding DJ, Stevens DA, Swarbrick ME, Wilson AW.

Bioorg Med Chem Lett. 2018 Jun 1;28(10):1892-1896. doi: 10.1016/j.bmcl.2018.03.091. Epub 2018 Mar 31.


A framework for identifying and selecting long term adaptation policy directions for deltas.

Suckall N, Tompkins EL, Nicholls RJ, Kebede AS, Lázár AN, Hutton C, Vincent K, Allan A, Chapman A, Rahman R, Ghosh T, Mensah A.

Sci Total Environ. 2018 Aug 15;633:946-957. doi: 10.1016/j.scitotenv.2018.03.234. Epub 2018 Mar 28.


Ectopic Overexpression of a Novel R2R3-MYB, NtMYB2 from Chinese Narcissus Represses Anthocyanin Biosynthesis in Tobacco.

Anwar M, Wang G, Wu J, Waheed S, Allan AC, Zeng L.

Molecules. 2018 Mar 28;23(4). pii: E781. doi: 10.3390/molecules23040781.


A randomized phase II study of pelareorep and docetaxel or docetaxel alone in men with metastatic castration resistant prostate cancer: CCTG study IND 209.

Eigl BJ, Chi K, Tu D, Hotte SJ, Winquist E, Booth CM, Canil C, Potvin K, Gregg R, North S, Zulfiqar M, Ellard S, Ruether JD, Le L, Kakumanu AS, Salim M, Allan AL, Feilotter H, Theis A, Seymour L.

Oncotarget. 2018 Jan 17;9(8):8155-8164. doi: 10.18632/oncotarget.24263. eCollection 2018 Jan 30.


The effect of 1-methylcyclopropene (1-MCP) on expression of ethylene receptor genes in durian pulp during ripening.

Thongkum M, Imsabai W, Burns P, McAtee PA, Schaffer RJ, Allan AC, Ketsa S.

Plant Physiol Biochem. 2018 Apr;125:232-238. doi: 10.1016/j.plaphy.2018.02.004. Epub 2018 Feb 10.


What have we been looking at? A call for consistency in studies of primate vigilance.

Allan ATL, Hill RA.

Am J Phys Anthropol. 2018 Jan;165 Suppl 65:4-22. doi: 10.1002/ajpa.23381. Review.


Solar UV light regulates flavonoid metabolism in apple (Malus x domestica).

Henry-Kirk RA, Plunkett B, Hall M, McGhie T, Allan AC, Wargent JJ, Espley RV.

Plant Cell Environ. 2018 Mar;41(3):675-688. doi: 10.1111/pce.13125. Epub 2018 Feb 5.


Tailoring Mathematical Models to Stem-Cell Derived Cardiomyocyte Lines Can Improve Predictions of Drug-Induced Changes to Their Electrophysiology.

Lei CL, Wang K, Clerx M, Johnstone RH, Hortigon-Vinagre MP, Zamora V, Allan A, Smith GL, Gavaghan DJ, Mirams GR, Polonchuk L.

Front Physiol. 2017 Dec 12;8:986. doi: 10.3389/fphys.2017.00986. eCollection 2017.


Circulating Tumor Cells and Implications of the Epithelial-to-Mesenchymal Transition.

Lowes LE, Allan AL.

Adv Clin Chem. 2018;83:121-181. doi: 10.1016/bs.acc.2017.10.004. Epub 2017 Dec 21. Review.


A survey of international antisepsis procedures for neuraxial catheterisation in labour.

Fayman K, Allan A, Hudson C, Logarta M.

Int J Obstet Anesth. 2018 Feb;33:8-16. doi: 10.1016/j.ijoa.2017.10.001. Epub 2017 Oct 6.


Neuronal RNA-binding protein HuD regulates addiction-related gene expression and behavior.

Oliver RJ, Brigman JL, Bolognani F, Allan AM, Neisewander JL, Perrone-Bizzozero NI.

Genes Brain Behav. 2018 Apr;17(4):e12454. doi: 10.1111/gbb.12454. Epub 2018 Jan 26.


Kiwifruit SVP2 controls developmental and drought-stress pathways.

Wu R, Wang T, Warren BAW, Thomson SJ, Allan AC, Macknight RC, Varkonyi-Gasic E.

Plant Mol Biol. 2018 Feb;96(3):233-244. doi: 10.1007/s11103-017-0688-3. Epub 2017 Dec 8.


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