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Effect of cardio-metabolic risk factors on all-cause mortality among HIV patients on antiretroviral therapy in Malawi: A prospective cohort study.

Amberbir A, Banda V, Singano V, Matengeni A, Pfaff C, Ismail Z, Allain TJ, Chan AK, Sodhi SK, van Oosterhout JJ.

PLoS One. 2019 Jan 17;14(1):e0210629. doi: 10.1371/journal.pone.0210629. eCollection 2019.


High mortality in subjects with both diabetes and HIV in sub-Saharan Africa.

Burgess PI, Harding SP, Kayange PC, van Oosterhout J, García-Fiñana M, Msukwa G, Allain TJ.

AIDS. 2018 Sep 10;32(14):2083-2084. doi: 10.1097/QAD.0000000000001929. No abstract available.


Use of an electronic medical record to monitor efficacy of diabetes care in out-patients in a central hospital in Malawi: Patterns of glycaemic control and lessons learned.

Allain TJ, Mang'anda G, Kasiya M, Khomani P, Banda NP, Gonani A, Peterson I, Dreyer G.

Malawi Med J. 2017 Dec;29(4):322-326. doi: 10.4314/mmj.v29i4.8.


HIV-associated disruption of lung cytokine networks is incompletely restored in asymptomatic HIV-infected Malawian adults on antiretroviral therapy.

Jambo KC, Tembo DL, Kamng'ona AW, Musicha P, Banda DH, Kankwatira AM, Malamba RD, Allain TJ, Heyderman RS, Russell DG, Mwandumba HC.

ERJ Open Res. 2017 Dec 14;3(4). pii: 00097-2017. doi: 10.1183/23120541.00097-2017. eCollection 2017 Oct.


Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults.

Peno C, Banda DH, Jambo N, Kankwatira AM, Malamba RD, Allain TJ, Ferreira DM, Heyderman RS, Russell DG, Mwandumba HC, Jambo KC.

J Infect. 2018 Feb;76(2):168-176. doi: 10.1016/j.jinf.2017.10.013. Epub 2017 Nov 29.


Goal directed therapy for suspected acute bacterial meningitis in adults and adolescents in sub-Saharan Africa.

Wall EC, Mukaka M, Denis B, Mlozowa VS, Msukwa M, Kasambala K, Nyrienda M, Allain TJ, Faragher B, Heyderman RS, Lalloo DG.

PLoS One. 2017 Oct 27;12(10):e0186687. doi: 10.1371/journal.pone.0186687. eCollection 2017.


The challenge of diabetic foot care: Review of the literature and experience at Queen Elizabeth Central Hospital in Blantyre, Malawi.

Kasiya MM, Mang'anda GD, Heyes S, Kachapila R, Kaduya L, Chilamba J, Goodson P, Chalulu K, Allain TJ.

Malawi Med J. 2017 Jun;29(2):218-223. Review. No abstract available.


The Role of Human Immunodeficiency Virus-Associated Vasculopathy in the Etiology of Stroke.

Benjamin LA, Allain TJ, Mzinganjira H, Connor MD, Smith C, Lucas S, Joekes E, Kampondeni S, Chetcuti K, Turnbull I, Hopkins M, Kamiza S, Corbett EL, Heyderman RS, Solomon T.

J Infect Dis. 2017 Sep 1;216(5):545-553. doi: 10.1093/infdis/jix340.


Incidence and progression of diabetic retinopathy in Sub-Saharan Africa: A five year cohort study.

Burgess PI, Harding SP, García-Fiñana M, Beare NAV, Glover S, Cohen DB, Msukwa G, Allain TJ.

PLoS One. 2017 Aug 2;12(8):e0181359. doi: 10.1371/journal.pone.0181359. eCollection 2017.


Genetic Determinants of the Pharmacokinetic Variability of Rifampin in Malawian Adults with Pulmonary Tuberculosis.

Sloan DJ, McCallum AD, Schipani A, Egan D, Mwandumba HC, Ward SA, Waterhouse D, Banda G, Allain TJ, Owen A, Khoo SH, Davies GR.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e00210-17. doi: 10.1128/AAC.00210-17. Print 2017 Jul.


Age Related Patterns of Disease and Mortality in Hospitalised Adults in Malawi.

Allain TJ, Aston S, Mapurisa G, Ganiza TN, Banda NP, Sakala S, Gonani A, Heyderman RS, Peterson I.

PLoS One. 2017 Jan 18;12(1):e0168368. doi: 10.1371/journal.pone.0168368. eCollection 2017.


The burden of hypertension, diabetes mellitus, and cardiovascular risk factors among adult Malawians in HIV care: consequences for integrated services.

Divala OH, Amberbir A, Ismail Z, Beyene T, Garone D, Pfaff C, Singano V, Akello H, Joshua M, Nyirenda MJ, Matengeni A, Berman J, Mallewa J, Chinomba GS, Kayange N, Allain TJ, Chan AK, Sodhi SK, van Oosterhout JJ.

BMC Public Health. 2016 Dec 12;16(1):1243.


Prediction of Outcome From Adult Bacterial Meningitis in a High-HIV-Seroprevalence, Resource-Poor Setting Using the Malawi Adult Meningitis Score (MAMS).

Wall EC, Mukaka M, Scarborough M, Ajdukiewicz KMA, Cartwright KE, Nyirenda M, Denis B, Allain TJ, Faragher B, Lalloo DG, Heyderman RS.

Clin Infect Dis. 2017 Feb 15;64(4):413-419. doi: 10.1093/cid/ciw779.


The spectrum of heart disease in adults in Malawi: A review of the literature with reference to the importance of echocardiography as a diagnostic modality.

Allain TJ, Kinley L, Tsidya B, Murray A, Cheesman M, Kampondeni S, Kayange N.

Malawi Med J. 2016 Jun;28(2):61-65. Review. No abstract available.


First Prospective Cohort Study of Diabetic Retinopathy from Sub-Saharan Africa: High Incidence and Progression of Retinopathy and Relationship to Human Immunodeficiency Virus Infection.

Burgess PI, Harding SP, García-Fiñana M, Beare NA, Msukwa G, Allain TJ.

Ophthalmology. 2016 Sep;123(9):1919-25. doi: 10.1016/j.ophtha.2016.05.042. Epub 2016 Jul 9.


Arterial ischemic stroke in HIV: Defining and classifying etiology for research studies.

Benjamin LA, Bryer A, Lucas S, Stanley A, Allain TJ, Joekes E, Emsley H, Turnbull I, Downey C, Toh CH, Brown K, Brown D, Ison C, Smith C, Corbett EL, Nath A, Heyderman RS, Connor MD, Solomon T.

Neurol Neuroimmunol Neuroinflamm. 2016 Jun 30;3(4):e254. doi: 10.1212/NXI.0000000000000254. eCollection 2016 Aug.


Oxygen saturations of medical inpatients in a Malawian hospital: cross-sectional study of oxygen supply and demand.

Evans HT, Mahmood N, Fullerton DG, Rylance J, Gonani A, Gordon SB, Mortimer K, Allain TJ.

Pneumonia (Nathan). 2016 Jul 2;1:3-6. doi: 10.15172/pneu.2012.1/208. eCollection 2012.


HIV, antiretroviral treatment, hypertension, and stroke in Malawian adults: A case-control study.

Benjamin LA, Corbett EL, Connor MD, Mzinganjira H, Kampondeni S, Choko A, Hopkins M, Emsley HC, Bryer A, Faragher B, Heyderman RS, Allain TJ, Solomon T.

Neurology. 2016 Jan 26;86(4):324-33. doi: 10.1212/WNL.0000000000002278. Epub 2015 Dec 18.


Falls and other geriatric syndromes in Blantyre, Malawi: a community survey of older adults.

Allain TJ, Mwambelo M, Mdolo T, Mfune P.

Malawi Med J. 2014 Dec;26(4):105-8.


Vitamin D deficiency in Malawian adults with pulmonary tuberculosis: risk factors and treatment outcomes.

Sloan DJ, Mwandumba HC, Kamdolozi M, Shani D, Chisale B, Dutton J, Khoo SH, Allain TJ, Davies GR.

Int J Tuberc Lung Dis. 2015 Aug;19(8):904-11. doi: 10.5588/ijtld.15.0071.


Rapid emergence of multidrug resistant, H58-lineage Salmonella typhi in Blantyre, Malawi.

Feasey NA, Gaskell K, Wong V, Msefula C, Selemani G, Kumwenda S, Allain TJ, Mallewa J, Kennedy N, Bennett A, Nyirongo JO, Nyondo PA, Zulu MD, Parkhill J, Dougan G, Gordon MA, Heyderman RS.

PLoS Negl Trop Dis. 2015 Apr 24;9(4):e0003748. doi: 10.1371/journal.pntd.0003748. eCollection 2015 Apr.


Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis.

Sloan DJ, Mwandumba HC, Garton NJ, Khoo SH, Butterworth AE, Allain TJ, Heyderman RS, Corbett EL, Barer MR, Davies GR.

Clin Infect Dis. 2015 Jul 1;61(1):1-8. doi: 10.1093/cid/civ195. Epub 2015 Mar 16.


Markers to differentiate between Kaposi's sarcoma and tuberculous pleural effusions in HIV-positive patients.

Coleman M, Finney LJ, Komrower D, Chitani A, Bates J, Chipungu GA, Corbett E, Allain TJ.

Int J Tuberc Lung Dis. 2015 Feb;19(2):144-50. doi: 10.5588/ijtld.14.0289.


A prospective study of mortality from cryptococcal meningitis following treatment induction with 1200 mg oral fluconazole in Blantyre, Malawi.

Gaskell KM, Rothe C, Gnanadurai R, Goodson P, Jassi C, Heyderman RS, Allain TJ, Harrison TS, Lalloo DG, Sloan DJ, Feasey NA.

PLoS One. 2014 Nov 6;9(11):e110285. doi: 10.1371/journal.pone.0110285. eCollection 2014.


Drug resistance in Salmonella enterica ser. Typhimurium bloodstream infection, Malawi.

Feasey NA, Cain AK, Msefula CL, Pickard D, Alaerts M, Aslett M, Everett DB, Allain TJ, Dougan G, Gordon MA, Heyderman RS, Kingsley RA.

Emerg Infect Dis. 2014 Nov;20(11):1957-9. doi: 10.3201/eid2011.141175. No abstract available.


Prevalence and spectrum of illness among hospitalized adults with malaria in Blantyre, Malawi.

Segula D, Frosch AP, SanJoaquin M, Taulo D, Skarbinski J, Mathanga DP, Allain TJ, Molyneux M, Laufer MK, Heyderman RS.

Malar J. 2014 Oct 2;13:391. doi: 10.1186/1475-2875-13-391.


Asymptomatic HIV-infected individuals on antiretroviral therapy exhibit impaired lung CD4(+) T-cell responses to mycobacteria.

Jambo KC, Banda DH, Afran L, Kankwatira AM, Malamba RD, Allain TJ, Gordon SB, Heyderman RS, Russell DG, Mwandumba HC.

Am J Respir Crit Care Med. 2014 Oct 15;190(8):938-47. doi: 10.1164/rccm.201405-0864OC.


Validation of the haemoglobin colour scale for screening blood donors in Malawi.

M'baya B, Mbingwani I, Mgawi L, Mkochi V, Bates I, White SA, Allain TJ.

Malawi Med J. 2014 Jun;26(2):30-3.


Sepsis carries a high mortality among hospitalised adults in Malawi in the era of antiretroviral therapy scale-up: a longitudinal cohort study.

Waitt PI, Mukaka M, Goodson P, SimuKonda FD, Waitt CJ, Feasey N, Allain TJ, Downie P, Heyderman RS.

J Infect. 2015 Jan;70(1):11-9. doi: 10.1016/j.jinf.2014.07.004. Epub 2014 Jul 17.


HIV associated neurocognitive disorders (HAND) in Malawian adults and effect on adherence to combination anti-retroviral therapy: a cross sectional study.

Kelly CM, van Oosterhout JJ, Ngwalo C, Stewart RC, Benjamin L, Robertson KR, Khoo S, Allain TJ, Solomon T.

PLoS One. 2014 Jun 10;9(6):e98962. doi: 10.1371/journal.pone.0098962. eCollection 2014.


High prevalence in Malawi of sight-threatening retinopathy and visual impairment caused by diabetes: identification of population-specific targets for intervention.

Burgess PI, Allain TJ, García-Fiñana M, Beare NA, Msukwa G, Harding SP.

Diabet Med. 2014 Dec;31(12):1643-50. doi: 10.1111/dme.12492. Epub 2014 Jun 7.


A reduction in adult blood stream infection and case fatality at a large African hospital following antiretroviral therapy roll-out.

Feasey NA, Houston A, Mukaka M, Komrower D, Mwalukomo T, Tenthani L, Jahn A, Moore M, Peters RP, Gordon MA, Everett DB, French N, van Oosterhout JJ, Allain TJ, Heyderman RS.

PLoS One. 2014 Mar 18;9(3):e92226. doi: 10.1371/journal.pone.0092226. eCollection 2014.


Small alveolar macrophages are infected preferentially by HIV and exhibit impaired phagocytic function.

Jambo KC, Banda DH, Kankwatira AM, Sukumar N, Allain TJ, Heyderman RS, Russell DG, Mwandumba HC.

Mucosal Immunol. 2014 Sep;7(5):1116-26. doi: 10.1038/mi.2013.127. Epub 2014 Jan 29.


Acute confusion and ataxia in the emergency department with an unexpected underlying diagnosis.

Phiri T, Allain TJ, Dreyer G.

Malawi Med J. 2013 Jun;25(2):33-5. No abstract available.


Utilization of ultrasound in medical inpatients in Malawi.

Brindle HE, Allain TJ, Kampondeni S, Kayange N, Faragher B, Bates I, Joekes E.

Trans R Soc Trop Med Hyg. 2013 Jul;107(7):405-10. doi: 10.1093/trstmh/trt034. Epub 2013 Jun 13.


Evaluation of Xpert MTB/RIF for detection of tuberculosis from blood samples of HIV-infected adults confirms Mycobacterium tuberculosis bacteremia as an indicator of poor prognosis.

Feasey NA, Banada PP, Howson W, Sloan DJ, Mdolo A, Boehme C, Chipungu GA, Allain TJ, Heyderman RS, Corbett EL, Alland D.

J Clin Microbiol. 2013 Jul;51(7):2311-6. doi: 10.1128/JCM.00330-13. Epub 2013 May 15.


Ward round: A 43-year-old diabetic man with multiple joint pains.

Segula D, Mahmood N, Allain TJ.

Malawi Med J. 2012 Dec;24(4):84-6. No abstract available.


Vitamin D deficiency in medical patients at a central hospital in Malawi: a comparison with TB patients from a previous study.

Mastala Y, Nyangulu P, Banda RV, Mhemedi B, White SA, Allain TJ.

PLoS One. 2013;8(3):e59017. doi: 10.1371/journal.pone.0059017. Epub 2013 Mar 28.


Surveillance Programme of IN-patients and Epidemiology (SPINE): implementation of an electronic data collection tool within a large hospital in Malawi.

SanJoaquin MA, Allain TJ, Molyneux ME, Benjamin L, Everett DB, Gadabu O, Rothe C, Nguipdop P, Chilombe M, Kazembe L, Sakala S, Gonani A, Heyderman RS.

PLoS Med. 2013;10(3):e1001400. doi: 10.1371/journal.pmed.1001400. Epub 2013 Mar 12.


Physical performance tests, self-reported outcomes, and accidental falls before and after total knee arthroplasty: an exploratory study.

Swinkels A, Allain TJ.

Physiother Theory Pract. 2013 Aug;29(6):432-42. doi: 10.3109/09593985.2012.755590. Epub 2013 Jan 4.


Stroke outcomes in Malawi, a country with high prevalence of HIV: a prospective follow-up study.

Heikinheimo T, Chimbayo D, Kumwenda JJ, Kampondeni S, Allain TJ.

PLoS One. 2012;7(3):e33765. doi: 10.1371/journal.pone.0033765. Epub 2012 Mar 29.


HIV post-exposure prophylaxis programmes in the developed and developing world: can we learn from each other?

van der Maaten GC, Davies J, Nyirenda M, Chitani A, Allain TJ, Beeching NJ, Beadsworth MB, van Oosterhout JJ.

Int J STD AIDS. 2011 Dec;22(12):751-2. doi: 10.1258/ijsa.2011.010423.


The prevalence of renal impairment among adults with early HIV disease in Blantyre, Malawi.

Struik GM, den Exter RA, Munthali C, Chipeta D, van Oosterhout JJ, Nouwen JL, Allain TJ.

Int J STD AIDS. 2011 Aug;22(8):457-62. doi: 10.1258/ijsa.2011.010521.


Applying lessons learnt from the 'DOTS' Tuberculosis Model to monitoring and evaluating persons with diabetes mellitus in Blantyre, Malawi.

Allain TJ, van Oosterhout JJ, Douglas GP, Joukes S, Gadabu OJ, Darts C, Kapur A, Harries AD.

Trop Med Int Health. 2011 Sep;16(9):1077-84. doi: 10.1111/j.1365-3156.2011.02808.x. Epub 2011 Jun 27.


Case report--the 46 year old man with a 5 month history of vomiting.

Segula D, Mwandiambira V, Howson W, Allain TJ.

Malawi Med J. 2011 Jun;23(2):55-7. No abstract available.


Prevalence of diabetic retinopathy, cataract and visual impairment in patients with diabetes in sub-Saharan Africa.

Glover SJ, Burgess PI, Cohen DB, Harding SP, Hofland HW, Zijlstra EE, Allain TJ.

Br J Ophthalmol. 2012 Feb;96(2):156-61. doi: 10.1136/bjo.2010.196071. Epub 2011 Apr 21.


Prevalence of vitamin D deficiency in adult tuberculosis patients at a central hospital in Malawi.

Banda R, Mhemedi B, Allain TJ.

Int J Tuberc Lung Dis. 2011 Mar;15(3):408-10.


Ward round-- non-resolving pleural effusion in a patient with HIV infection.

Nyirenda M, Gray KJ, Allain TJ, van Oosterhout JJ.

Malawi Med J. 2009 Dec;21(4):182-3. No abstract available.


A survey of the management, control, and complications of diabetes mellitus in patients attending a diabetes clinic in Blantyre, Malawi, an area of high HIV prevalence.

Cohen DB, Allain TJ, Glover S, Chimbayo D, Dzamalala H, Hofland HW, Banda NP, Zijlstra EE.

Am J Trop Med Hyg. 2010 Sep;83(3):575-81. doi: 10.4269/ajtmh.2010.10-0104.


Using touchscreen electronic medical record systems to support and monitor national scale-up of antiretroviral therapy in Malawi.

Douglas GP, Gadabu OJ, Joukes S, Mumba S, McKay MV, Ben-Smith A, Jahn A, Schouten EJ, Landis Lewis Z, van Oosterhout JJ, Allain TJ, Zachariah R, Berger SD, Harries AD, Chimbwandira F.

PLoS Med. 2010 Aug 10;7(8). pii: e1000319. doi: 10.1371/journal.pmed.1000319. No abstract available.

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