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Items: 6


Dysregulated NK cell PLCγ2 signaling and activity in juvenile dermatomyositis.

Throm AA, Alinger JB, Pingel JT, Daugherty AL, Pachman LM, French AR.

JCI Insight. 2018 Nov 15;3(22). pii: 123236. doi: 10.1172/jci.insight.123236.


Glycolytic requirement for NK cell cytotoxicity and cytomegalovirus control.

Mah AY, Rashidi A, Keppel MP, Saucier N, Moore EK, Alinger JB, Tripathy SK, Agarwal SK, Jeng EK, Wong HC, Miller JS, Fehniger TA, Mace EM, French AR, Cooper MA.

JCI Insight. 2017 Dec 7;2(23). pii: 95128. doi: 10.1172/jci.insight.95128.


VP24-Karyopherin Alpha Binding Affinities Differ between Ebolavirus Species, Influencing Interferon Inhibition and VP24 Stability.

Schwarz TM, Edwards MR, Diederichs A, Alinger JB, Leung DW, Amarasinghe GK, Basler CF.

J Virol. 2017 Jan 31;91(4). pii: e01715-16. doi: 10.1128/JVI.01715-16. Print 2017 Feb 15.


Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.

Xu W, Edwards MR, Borek DM, Feagins AR, Mittal A, Alinger JB, Berry KN, Yen B, Hamilton J, Brett TJ, Pappu RV, Leung DW, Basler CF, Amarasinghe GK.

Cell Host Microbe. 2014 Aug 13;16(2):187-200. doi: 10.1016/j.chom.2014.07.008.


Lipids derived from virulent Francisella tularensis broadly inhibit pulmonary inflammation via toll-like receptor 2 and peroxisome proliferator-activated receptor α.

Crane DD, Ireland R, Alinger JB, Small P, Bosio CM.

Clin Vaccine Immunol. 2013 Oct;20(10):1531-40. doi: 10.1128/CVI.00319-13. Epub 2013 Aug 7.


Francisella tularensis SchuS4 and SchuS4 lipids inhibit IL-12p40 in primary human dendritic cells by inhibition of IRF1 and IRF8.

Ireland R, Wang R, Alinger JB, Small P, Bosio CM.

J Immunol. 2013 Aug 1;191(3):1276-86. doi: 10.4049/jimmunol.1300867. Epub 2013 Jul 1.

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