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Br J Ophthalmol. 1997 Sep;81(9):732-4.

Topical steroid use in the treatment of ocular alkali burns.

Author information

1
King's College Hospital, Denmark Hill, London.

Erratum in

  • Br J Ophthalmol 1998 Feb;82(2):207. Ali QH [corrected to Ali QK].

Abstract

BACKGROUND:

Ocular alkali burns can be associated with a poor visual outcome. The release of collagenases and proteases after the injury leads to corneoscleral melting. The role of topical steroids in such patients is controversial as they have been postulated to exacerbate corneoscleral melting.

METHODS:

30 patients were reviewed retrospectively after admission to King's College Hospital with alkali burns between 1990 and 1993. All patients were treated with an intense and prolonged regimen of topical steroids and topical and systemic vitamin C.

RESULTS:

22 patients had mild injuries and eight had severe injuries as estimated by the Roper-Hall grading system. 23 patients were treated with topical steroids for > 10 days and 22 patients were treated with topical vitamin C for more than 10 days. One patient with a severe injury developed corneoscleral melting.

CONCLUSION:

Prolonged treatment with topical steroids when used in conjunction with topical vitamin C is not associated with corneoscleral melting.

PMID:
9422923
PMCID:
PMC1722301
DOI:
10.1136/bjo.81.9.732
[Indexed for MEDLINE]
Free PMC Article

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