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Items: 44

1.

Effect of dexamethasone on the activity and expression of ornithine decarboxylase in rat liver and thymus.

Hirvonen A, Immonen T, Leinonen P, Alhonen-Hongisto L, Jänne OA, Jänne J.

Biochim Biophys Acta. 1988 Jul 13;950(2):229-33.

PMID:
3382666
2.
4.

Chronic exposure to dexamethasone induces hypomethylation of ornithine decarboxylase genes in a human myeloma cell line.

Leinonen P, Alhonen-Hongisto L, Laine R, Jänne OA, Jänne J.

FEBS Lett. 1987 May 4;215(1):68-72.

5.

Human myeloma cells acquire resistance to difluoromethylornithine without overproducing ornithine decarboxylase.

Alhonen-Hongisto L, Leinonen P, Laine R, Jänne J.

Biochem Biophys Res Commun. 1987 Apr 14;144(1):132-7.

PMID:
3107550
6.

Human myeloma cells acquire resistance to difluoromethylornithine by amplification of ornithine decarboxylase gene.

Leinonen P, Alhonen-Hongisto L, Laine R, Jänne OA, Jänne J.

Biochem J. 1987 Feb 15;242(1):199-203.

7.

Mouse and human ornithine decarboxylase genes. Methylation polymorphism and amplification.

Alhonen-Hongisto L, Leinonen P, Sinervirta R, Laine R, Winqvist R, Alitalo K, Jänne OA, Jänne J.

Biochem J. 1987 Feb 15;242(1):205-10.

8.

Biochemical properties and crystal structure of ethylmethylglyoxal bis(guanylhydrazone) sulfate--an extremely powerful novel inhibitor of adenosylmethionine decarboxylase.

Elo H, Mutikainen I, Alhonen-Hongisto L, Laine R, Jänne J, Lumme P.

Z Naturforsch C. 1986 Sep-Oct;41(9-10):851-5.

PMID:
2948329
9.

Human ornithine decarboxylase sequences map to chromosome regions 2pter----p23 and 7cen----qter but are not coamplified with the NMYC oncogene.

Winqvist R, Mäkelä TP, Seppänen P, Jänne OA, Alhonen-Hongisto L, Jänne J, Grzeschik KH, Alitalo K.

Cytogenet Cell Genet. 1986;42(3):133-40.

PMID:
3755388
10.
11.

Biochemical characterization of propylglyoxal bis(guanylhydrazone). Facile synthesis of monoalkylglyoxal bis(guanylhydrazones).

Elo H, Laine R, Alhonen-Hongisto L, Jänne J, Mutikainen I, Lumme P.

Z Naturforsch C. 1985 Nov-Dec;40(11-12):839-42.

PMID:
3832666
12.

Effects of bis(guanylhydrazones) on the activity and expression of ornithine decarboxylase.

Nikula P, Alhonen-Hongisto L, Jänne J.

Biochem J. 1985 Oct 1;231(1):213-6.

13.

Tumourigenicity, cell-surface glycoprotein changes and ornithine decarboxylase gene pattern in Ehrlich ascites-carcinoma cells.

Alhonen-Hongisto L, Kallio A, Sinervirta R, Jänne OA, Gahmberg CG, Jänne J.

Biochem J. 1985 Aug 1;229(3):711-5.

14.
16.

Difluoromethylornithine-induced amplification of ornithine decarboxylase genes in Ehrlich ascites carcinoma cells.

Alhonen-Hongisto L, Kallio A, Sinervirta R, Seppänen P, Kontula KK, Jänne OA, Jänne J.

Biochem Biophys Res Commun. 1985 Jan 31;126(2):734-40.

PMID:
2983688
17.

S-adenosylmethionine decarboxylase as target of chemotherapy.

Jänne J, Alhonen-Hongisto L, Nikula P, Elo H.

Adv Enzyme Regul. 1985;24:125-39. Review.

PMID:
3939095
19.

Glyoxal bis(guanylhydrazone) as an inhibitor of polyamine biosynthesis in tumour cells.

Seppänen P, Fagerström R, Alhonen-Hongisto L, Elo H, Lumme P, Jänne J.

Biochem J. 1984 Jul 15;221(2):483-8.

20.

Different efflux rates may determine the cellular accumulation of various bis(guanylhydrazones).

Alhonen-Hongisto L, Fagerström R, Laine R, Elo H, Jänne J.

Biochem J. 1984 Jul 1;221(1):273-6.

22.

Inhibition of long-chain fatty acid oxidation by methylglyoxal bis(guanylhydrazone).

Nikula P, Alhonen-Hongisto L, Seppänen P, Jänne J.

Biochem Biophys Res Commun. 1984 Apr 16;120(1):9-14.

PMID:
6712703
23.
24.
25.

Combined use of 2-difluoromethylornithine and methylglyoxal bis(guanylhydrazone) in normal and leukemia-bearing mice.

Seppänen P, Alhonen-Hongisto L, Jänne J.

Cancer Lett. 1983 Feb;18(1):1-10.

PMID:
6402294
26.

Two enzyme inhibition assays for methylglyoxal bis(guanylhydrazone).

Seppänen P, Alhonen-Hongisto L, Käpyaho K, Jänne J.

Methods Enzymol. 1983;94:247-53. No abstract available.

PMID:
6413819
27.
28.

Methylglyoxal bis(guanylhydrazone) stimulates the cellular transport system of the polyamines.

Alhonen-Hongisto L, Seppänen P, Jänne J.

FEBS Lett. 1982 Aug 23;145(2):182-6. No abstract available.

29.

Indirect determination of methylglyoxal bis(guanylhydrazone) in leukocytes of leukemia patients.

Seppänen P, Alhonen-Hongisto L, Jänne J, Raina A, Eloranta T.

Clin Chim Acta. 1982 Aug 4;123(1-2):187-92. No abstract available.

PMID:
7116638
30.

Replacement of natural polyamines by cadaverine and its aminopropyl derivatives in Ehrlich ascites carcinoma cells.

Alhonen-Hongisto L, Seppänen P, Hölttä E, Jänne J.

Biochem Biophys Res Commun. 1982 May 31;106(2):291-7. No abstract available.

PMID:
6809002
31.

Polyamines in mycoplasmas and in mycoplasma-infected tumour cells.

Alhonen-Hongisto L, Veijalainen P, Ek-Kommonen C, Jänne J.

Biochem J. 1982 Jan 15;202(1):267-70.

32.

Use of polyamine antimetabolites in experimental tumours and in human leukemia.

Jänne J, Alhonen-Hongisto L, Seppänen P, Siimes M.

Med Biol. 1981 Dec;59(5-6):448-57. Review. No abstract available.

PMID:
6803081
33.

Synergistic action of two polyamine antimetabolites leads to a rapid therapeutic response in childhood leukemia.

Siimes M, Seppänen P, Alhonen-Hongisto L, Jänne J.

Int J Cancer. 1981 Nov 15;28(5):567-70.

PMID:
6796528
34.

Death of tumor cells in response to the use of a system of stimulated polyamine uptake from the transport of methylglyoxal bis(guanylhydrazone).

Seppänen P, Alhonen-Hongisto L, Jänne J.

Eur J Biochem. 1981 Sep 1;118(3):571-6. No abstract available.

35.

Polyamine deprivation-induced enhanced uptake of methylglyoxal bis(guanylhydrazone) by tumor cells.

Seppänen P, Alhonen-Hongisto L, Jänne J.

Biochim Biophys Acta. 1981 May 5;674(2):169-77.

PMID:
6786360
37.

Quantitation of methylglyoxal bis(guanylhydrazone) in blood plasma and leukemia cells of patients receiving the drug.

Seppänen P, Alhonen-Hongisto L, Siimes M, Jänne J.

Int J Cancer. 1980 Nov 15;26(5):571-6.

PMID:
6940849
39.

Relation of the antiproliferative action of methylglyoxal-bis(guanylhydrazone) to the natural polyamines.

Seppänen P, Alhonen-Hongisto L, Jänne J.

Eur J Biochem. 1980 Sep;110(1):7-12.

40.
41.

Polyamine depletion induces enhanced synthesis and accumulation of cadaverine in cultured Ehrlich ascites carcinoma cells.

Alhonen-Hongisto L, Jänne J.

Biochem Biophys Res Commun. 1980 Apr 29;93(4):1005-13. No abstract available.

PMID:
6772174
42.

Sensitive enzymic determination of methylglyoxal bis(guanylhydrazone) in cultured cells and in animal tissues.

Seppänen P, Alhonen-Hongisto L, Pösö H, Jänne J.

FEBS Lett. 1980 Feb 25;111(1):99-103. No abstract available.

43.

Inhibition of polyamine accumulation and cell proliferation by derivatives of diaminopropane in Ehrlich ascites cells grown in culture.

Alhonen-Hongisto L, Pösö H, Jänne J.

Biochim Biophys Acta. 1979 Oct 25;564(3):473-87.

PMID:
497223
44.

Effect of inhibitors on ornithine and adenosylmethionine decarboxylases on the synthesis of deoxyribonucleic acid in Ehrlich ascites cells in vivo.

Alhonen-Hongisto L, Kallio A, Pösö H, Jänne J.

Acta Chem Scand B. 1979;33(8):559-66. No abstract available.

PMID:
532500

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