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Items: 1 to 50 of 162

1.

Carotenoid Intake and Serum Concentration in Young Finnish Children and Their Relation with Fruit and Vegetable Consumption.

Prasad M, Takkinen HM, Uusitalo L, Tapanainen H, Ovaskainen ML, Alfthan G, Erlund I, Ahonen S, Åkerlund M, Toppari J, Ilonen J, Knip M, Veijola R, Virtanen SM.

Nutrients. 2018 Oct 17;10(10). pii: E1533. doi: 10.3390/nu10101533.

2.

Standardisation of laboratories engaged in lipid analyses of population health examination surveys.

Alfthan G, Sundvall J, Råman L, Kuulasmaa K, Tolonen H; European Health Examination Survey Pilot Project.

J Epidemiol Community Health. 2018 Jul;72(7):653-657. doi: 10.1136/jech-2018-210763. Epub 2018 Apr 10.

PMID:
29636400
3.

Food and Nutrient Intake and Nutritional Status of Finnish Vegans and Non-Vegetarians.

Elorinne AL, Alfthan G, Erlund I, Kivimäki H, Paju A, Salminen I, Turpeinen U, Voutilainen S, Laakso J.

PLoS One. 2016 Feb 3;11(2):e0148235. doi: 10.1371/journal.pone.0148235. eCollection 2016. Erratum in: PLoS One. 2016;11(3):e0151296.

4.

Poor micronutrient intake and status is a public health problem among adolescent Mozambican girls.

Korkalo L, Freese R, Alfthan G, Fidalgo L, Mutanen M.

Nutr Res. 2015 Aug;35(8):664-73. doi: 10.1016/j.nutres.2015.05.013. Epub 2015 May 30.

PMID:
26077868
5.

Effects of nationwide addition of selenium to fertilizers on foods, and animal and human health in Finland: From deficiency to optimal selenium status of the population.

Alfthan G, Eurola M, Ekholm P, Venäläinen ER, Root T, Korkalainen K, Hartikainen H, Salminen P, Hietaniemi V, Aspila P, Aro A; Selenium Working Group.

J Trace Elem Med Biol. 2015;31:142-7. doi: 10.1016/j.jtemb.2014.04.009. Epub 2014 May 20. Review.

PMID:
24908353
6.

Serum vitamin E concentrations at 1 year and risk of atopy, atopic dermatitis, wheezing, and asthma in childhood: the PASTURE study.

Nwaru BI, Virtanen SM, Alfthan G, Karvonen AM, Genuneit J, Lauener RP, Dalphin JC, Hyvärinen A, Pfefferle P, Riedler J, Weber J, Roduit C, Kaulek V, Braun-Fahrländer C, von Mutius E, Pekkanen J; PASTURE study group.

Allergy. 2014 Jan;69(1):87-94. doi: 10.1111/all.12307. Epub 2013 Nov 11.

PMID:
24205866
7.

Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.

Seppälä I, Kleber ME, Lyytikäinen LP, Hernesniemi JA, Mäkelä KM, Oksala N, Laaksonen R, Pilz S, Tomaschitz A, Silbernagel G, Boehm BO, Grammer TB, Koskinen T, Juonala M, Hutri-Kähönen N, Alfthan G, Viikari JS, Kähonen M, Raitakari OT, März W, Meinitzer A, Lehtimäki T; AtheroRemo Consortium.

Eur Heart J. 2014 Feb;35(8):524-31. doi: 10.1093/eurheartj/eht447. Epub 2013 Oct 24.

8.

The effect of proatherogenic pathogens on adipose tissue transcriptome and fatty acid distribution in apolipoprotein E-deficient mice.

Hyvärinen K, Tuomainen AM, Laitinen S, Alfthan G, Salminen I, Leinonen M, Saikku P, Kovanen PT, Jauhiainen M, Pussinen PJ.

BMC Genomics. 2013 Oct 17;14:709. doi: 10.1186/1471-2164-14-709.

9.

Vegetable and fruit consumption, education and plasma vitamin C concentration in Russian and Finnish Karelia, 1992-2002.

Paalanen L, Prättälä R, Alfthan G, Salminen I, Laatikainen T.

Public Health Nutr. 2014 Oct;17(10):2278-86. doi: 10.1017/S1368980013002243. Epub 2013 Aug 30.

PMID:
23987990
10.

Seasonal variation in plasma vitamin C concentration in Pitkäranta, Northwestern Russia.

Paalanen L, Prättälä R, Alfthan G, Salminen I, Laatikainen T.

Eur J Clin Nutr. 2013 Oct;67(10):1115. doi: 10.1038/ejcn.2012.185. Epub 2012 Nov 28. No abstract available.

PMID:
23187952
11.

What have we learnt about high-density lipoprotein cholesterol measurements during 32 years? Experiences in Finland 1980-2012.

Leiviskä J, Sundvall J, Alfthan G, Tähtelä R, Salomaa V, Jauhiainen M, Vartiainen E.

Clin Chim Acta. 2013 Jan 16;415:118-23. doi: 10.1016/j.cca.2012.10.027. Epub 2012 Oct 18.

PMID:
23085381
12.

Rye bread intake improves oxidation resistance of LDL in healthy humans.

Söderholm PP, Alfthan G, Tikkanen MJ, Adlercreutz H.

Atherosclerosis. 2012 Apr;221(2):583-6. doi: 10.1016/j.atherosclerosis.2012.01.030. Epub 2012 Jan 25.

PMID:
22336172
13.

Fatty acids in serum and diet--a canonical correlation analysis among toddlers.

Uusitalo L, Nevalainen J, Salminen I, Ovaskainen ML, Kronberg-Kippilä C, Ahonen S, Niinistö S, Alfthan G, Simell O, Ilonen J, Veijola R, Knip M, Virtanen SM.

Matern Child Nutr. 2013 Jul;9(3):381-95. doi: 10.1111/j.1740-8709.2011.00374.x. Epub 2011 Nov 8.

PMID:
22066932
14.

The use of fasting vs. non-fasting triglyceride concentration for estimating the prevalence of high LDL-cholesterol and metabolic syndrome in population surveys.

Sundvall J, Leiviskä J, Laatikainen T, Peltonen M, Salomaa V, Vanhala M, Korpi-Hyövälti E, Lauronen J, Alfthan G.

BMC Med Res Methodol. 2011 May 10;11:63. doi: 10.1186/1471-2288-11-63.

15.

Selenium status and blood lipids: the cardiovascular risk in Young Finns study.

Stranges S, Tabák AG, Guallar E, Rayman MP, Akbaraly TN, Laclaustra M, Alfthan G, Mussalo-Rauhamaa H, Viikari JS, Raitakari OT, Kivimäki M.

J Intern Med. 2011 Nov;270(5):469-77. doi: 10.1111/j.1365-2796.2011.02398.x. Epub 2011 Jun 1.

16.

Apolipoprotein A-I, apolipoprotein B, and apolipoprotein B/apolipoprotein A-I ratio: reference intervals compared with values in different pathophysiological conditions from the FINRISK 2007 study.

Leiviskä J, Sundvall J, Alfthan G, Jauhiainen M, Salomaa V.

Clin Chim Acta. 2011 May 12;412(11-12):1146-50. doi: 10.1016/j.cca.2011.03.015. Epub 2011 Mar 17.

PMID:
21419755
17.

The effect of high-fiber rye bread enriched with nonesterified plant sterols on major serum lipids and apolipoproteins in normocholesterolemic individuals.

Söderholm PP, Alfthan G, Koskela AH, Adlercreutz H, Tikkanen MJ.

Nutr Metab Cardiovasc Dis. 2012 Jul;22(7):575-82. doi: 10.1016/j.numecd.2010.09.011. Epub 2011 Jan 6.

PMID:
21215605
18.

Are serum α- and β-carotene concentrations associated with the development of advanced beta-cell autoimmunity in children with increased genetic susceptibility to type 1 diabetes?

Prasad M, Takkinen HM, Nevalainen J, Ovaskainen ML, Alfthan G, Uusitalo L, Kenward MG, Veijola R, Simell O, Ilonen J, Knip M, Virtanen SM.

Diabetes Metab. 2011 Apr;37(2):162-7. doi: 10.1016/j.diabet.2010.10.002. Epub 2010 Dec 7.

PMID:
21144788
19.

Long-term effect of betaine on risk factors associated with the metabolic syndrome in healthy subjects.

Schwab U, Alfthan G, Aro A, Uusitupa M.

Eur J Clin Nutr. 2011 Jan;65(1):70-6. doi: 10.1038/ejcn.2010.230. Epub 2010 Oct 27.

PMID:
20978525
20.

Levels of asymmetrical dimethylarginine are predictive of brachial artery flow-mediated dilation 6 years later. The Cardiovascular Risk in Young Finns Study.

Päivä H, Kähönen M, Lehtimäki T, Alfthan G, Viikari J, Laaksonen R, Hutri-Kähönen N, Laitinen T, Taittonen L, Raitakari OT, Juonala M.

Atherosclerosis. 2010 Oct;212(2):512-5. doi: 10.1016/j.atherosclerosis.2010.06.041. Epub 2010 Jul 22.

PMID:
20655043
21.

Serum fatty acids and risk of advanced beta-cell autoimmunity: a nested case-control study among children with HLA-conferred susceptibility to type I diabetes.

Virtanen SM, Niinistö S, Nevalainen J, Salminen I, Takkinen HM, Kääriä S, Uusitalo L, Alfthan G, Kenward MG, Veijola R, Simell O, Ilonen J, Knip M.

Eur J Clin Nutr. 2010 Aug;64(8):792-9. doi: 10.1038/ejcn.2010.75. Epub 2010 May 26.

PMID:
20502469
22.

Bioavailability of various polyphenols from a diet containing moderate amounts of berries.

Koli R, Erlund I, Jula A, Marniemi J, Mattila P, Alfthan G.

J Agric Food Chem. 2010 Apr 14;58(7):3927-32. doi: 10.1021/jf9024823.

PMID:
20073463
23.

ADMA concentration changes across the menstrual cycle and during oral contraceptive use: the Cardiovascular Risk in Young Finns Study.

Valtonen P, Punnonen K, Saarelainen H, Heiskanen N, Raitakari OT, Juonala M, Viikari JS, Alfthan G, Kähönen M, Laaksonen R, Lyyra-Laitinen T, Laitinen T, Heinonen S.

Eur J Endocrinol. 2010 Feb;162(2):259-65. doi: 10.1530/EJE-09-0658. Epub 2009 Nov 24.

PMID:
19934267
24.

Chlamydial and periodontal pathogens induce hepatic inflammation and fatty acid imbalance in apolipoprotein E-deficient mice.

Hyvärinen K, Tuomainen AM, Laitinen S, Bykov IL, Törmäkangas L, Lindros K, Käkelä R, Alfthan G, Salminen I, Jauhiainen M, Kovanen PT, Leinonen M, Saikku P, Pussinen PJ.

Infect Immun. 2009 Aug;77(8):3442-9. doi: 10.1128/IAI.00389-09. Epub 2009 May 18.

25.

Tracking of plasma antibodies against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis during 15 years.

Lakio L, Antinheimo J, Paju S, Buhlin K, Pussinen PJ, Alfthan G.

J Oral Microbiol. 2009 Aug 3;1. doi: 10.3402/jom.v1i0.1979.

26.

Serum and dietary beta-carotene and alpha-tocopherol and incidence of type 2 diabetes mellitus in a community-based study of Swedish men: report from the Uppsala Longitudinal Study of Adult Men (ULSAM) study.

Arnlöv J, Zethelius B, Risérus U, Basu S, Berne C, Vessby B, Alfthan G, Helmersson J; Uppsala Longitudinal Study of Adult Men Study.

Diabetologia. 2009 Jan;52(1):97-105. doi: 10.1007/s00125-008-1189-3. Epub 2008 Nov 5.

PMID:
18985315
27.

Systematic error of serum triglyceride measurements during three decades and the effect of fasting on serum triglycerides in population studies.

Sundvall J, Laatikainen T, Hakala S, Leiviskä J, Alfthan G.

Clin Chim Acta. 2008 Nov;397(1-2):55-9. doi: 10.1016/j.cca.2008.07.015. Epub 2008 Jul 18.

PMID:
18687321
28.

Asymmetric dimethylarginine (ADMA) has a role in regulating systemic vascular tone in young healthy subjects: the cardiovascular risk in young Finns study.

Päivä H, Kähönen M, Lehtimäki T, Raitakari OT, Jula A, Viikari J, Alfthan G, Juonala M, Laaksonen R, Hutri-Kähönen N.

Am J Hypertens. 2008 Aug;21(8):873-8. doi: 10.1038/ajh.2008.215. Epub 2008 Jun 12.

PMID:
18551100
29.

Plasma ascorbic acid preparation and storage for epidemiological studies using TCA precipitation.

Salminen I, Alfthan G.

Clin Biochem. 2008 Jun;41(9):723-7. doi: 10.1016/j.clinbiochem.2007.01.026. Epub 2007 Jun 21.

PMID:
18371942
30.

Serum alpha- and gamma-tocopherol concentrations and risk of advanced beta cell autoimmunity in children with HLA-conferred susceptibility to type 1 diabetes mellitus.

Uusitalo L, Nevalainen J, Niinistö S, Alfthan G, Sundvall J, Korhonen T, Kenward MG, Oja H, Veijola R, Simell O, Ilonen J, Knip M, Virtanen SM.

Diabetologia. 2008 May;51(5):773-80. doi: 10.1007/s00125-008-0959-2. Epub 2008 Mar 4.

PMID:
18317723
31.

Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol.

Erlund I, Koli R, Alfthan G, Marniemi J, Puukka P, Mustonen P, Mattila P, Jula A.

Am J Clin Nutr. 2008 Feb;87(2):323-31.

PMID:
18258621
32.

Brachial artery flow-mediated dilation and asymmetrical dimethylarginine in the cardiovascular risk in young Finns study.

Juonala M, Viikari JS, Alfthan G, Marniemi J, Kähönen M, Taittonen L, Laitinen T, Raitakari OT.

Circulation. 2007 Sep 18;116(12):1367-73. Epub 2007 Aug 27.

PMID:
17724260
33.

Tomato juice decreases LDL cholesterol levels and increases LDL resistance to oxidation.

Silaste ML, Alfthan G, Aro A, Kesäniemi YA, Hörkkö S.

Br J Nutr. 2007 Dec;98(6):1251-8. Epub 2007 Jul 9.

PMID:
17617941
34.

Functional COMT Val158Met polymorphism, risk of acute coronary events and serum homocysteine: the Kuopio ischaemic heart disease risk factor study.

Voutilainen S, Tuomainen TP, Korhonen M, Mursu J, Virtanen JK, Happonen P, Alfthan G, Erlund I, North KE, Mosher MJ, Kauhanen J, Tiihonen J, Kaplan GA, Salonen JT.

PLoS One. 2007 Jan 31;2(1):e181.

35.

Serum cholesterol during 27 years: assessment of systematic error and affecting factors and their role in interpreting population trends.

Sundvall J, Leiviskä J, Alfthan G, Vartiainen E.

Clin Chim Acta. 2007 Mar;378(1-2):93-8. Epub 2006 Dec 12.

PMID:
17169352
36.

Consumption of juice fortified with oregano extract markedly increases excretion of phenolic acids but lacks short- and long-term effects on lipid peroxidation in healthy nonsmoking men.

Nurmi A, Mursu J, Nurmi T, Nyyssönen K, Alfthan G, Hiltunen R, Kaikkonen J, Salonen JT, Voutilainen S.

J Agric Food Chem. 2006 Aug 9;54(16):5790-6.

PMID:
16881679
37.

Systemic exposure to Porphyromonas gingivalis predicts incident stroke.

Pussinen PJ, Alfthan G, Jousilahti P, Paju S, Tuomilehto J.

Atherosclerosis. 2007 Jul;193(1):222-8. Epub 2006 Jul 26.

PMID:
16872615
38.

Bioavailability of quercetin from berries and the diet.

Erlund I, Freese R, Marniemi J, Hakala P, Alfthan G.

Nutr Cancer. 2006;54(1):13-7. Review.

PMID:
16800769
39.

Serum enterolactone concentration and the risk of coronary heart disease in a case-cohort study of Finnish male smokers.

Kilkkinen A, Erlund I, Virtanen MJ, Alfthan G, Ariniemi K, Virtamo J.

Am J Epidemiol. 2006 Apr 15;163(8):687-93. Epub 2006 Mar 1.

PMID:
16510545
40.

Serum alpha-tocopherol concentrations and risk of type 1 diabetes mellitus: a cohort study in siblings of affected children.

Uusitalo L, Knip M, Kenward MG, Alfthan G, Sundvall J, Aro A, Reunanen A, Akerblom HK, Virtanen SM; Childhood Diabetes in Finland Study Group.

J Pediatr Endocrinol Metab. 2005 Dec;18(12):1409-16.

PMID:
16459467
41.

Orally administered betaine has an acute and dose-dependent effect on serum betaine and plasma homocysteine concentrations in healthy humans.

Schwab U, Törrönen A, Meririnne E, Saarinen M, Alfthan G, Aro A, Uusitupa M.

J Nutr. 2006 Jan;136(1):34-8. Erratum in: J Nutr. 2007 Apr;137(4):1124.

PMID:
16365055
42.

Serum homocysteine, folate and risk of stroke: Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study.

Virtanen JK, Voutilainen S, Happonen P, Alfthan G, Kaikkonen J, Mursu J, Rissanen TH, Kaplan GA, Korhonen MJ, Sivenius J, Salonen JT.

Eur J Cardiovasc Prev Rehabil. 2005 Aug;12(4):369-75.

PMID:
16079645
43.

Serum selenium predicts levels of F2-isoprostanes and prostaglandin F2alpha in a 27 year follow-up study of Swedish men.

Helmersson J, Arnlöv J, Vessby B, Larsson A, Alfthan G, Basu S.

Free Radic Res. 2005 Jul;39(7):763-70.

PMID:
16036356
44.

Homocysteine as a risk factor for CVD mortality in men with other CVD risk factors: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study.

Virtanen JK, Voutilainen S, Alfthan G, Korhonen MJ, Rissanen TH, Mursu J, Kaplan GA, Salonen JT.

J Intern Med. 2005 Mar;257(3):255-62.

45.

Serum antibody levels to Actinobacillus actinomycetemcomitans predict the risk for coronary heart disease.

Pussinen PJ, Nyyssönen K, Alfthan G, Salonen R, Laukkanen JA, Salonen JT.

Arterioscler Thromb Vasc Biol. 2005 Apr;25(4):833-8. Epub 2005 Feb 3.

PMID:
15692101
46.

The effects of coffee consumption on lipid peroxidation and plasma total homocysteine concentrations: a clinical trial.

Mursu J, Voutilainen S, Nurmi T, Alfthan G, Virtanen JK, Rissanen TH, Happonen P, Nyyssönen K, Kaikkonen J, Salonen R, Salonen JT.

Free Radic Biol Med. 2005 Feb 15;38(4):527-34.

PMID:
15649655
47.

High serum antibody levels to Porphyromonas gingivalis predict myocardial infarction.

Pussinen PJ, Alfthan G, Tuomilehto J, Asikainen S, Jousilahti P.

Eur J Cardiovasc Prev Rehabil. 2004 Oct;11(5):408-11.

PMID:
15616414
48.

Association between depressive symptoms and serum concentrations of homocysteine in men: a population study.

Tolmunen T, Hintikka J, Voutilainen S, Ruusunen A, Alfthan G, Nyyssönen K, Viinamäki H, Kaplan GA, Salonen JT.

Am J Clin Nutr. 2004 Dec;80(6):1574-8.

PMID:
15585771
49.

The effect of low doses of betaine on plasma homocysteine in healthy volunteers.

Alfthan G, Tapani K, Nissinen K, Saarela J, Aro A.

Br J Nutr. 2004 Oct;92(4):665-9.

PMID:
15522136
50.

Severe periodontitis enhances macrophage activation via increased serum lipopolysaccharide.

Pussinen PJ, Vilkuna-Rautiainen T, Alfthan G, Palosuo T, Jauhiainen M, Sundvall J, Vesanen M, Mattila K, Asikainen S.

Arterioscler Thromb Vasc Biol. 2004 Nov;24(11):2174-80. Epub 2004 Sep 23.

PMID:
15388525

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