Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 78

1.

Deactivating Fatty Acids: Acyl-CoA Thioesterase-Mediated Control of Lipid Metabolism.

Tillander V, Alexson SEH, Cohen DE.

Trends Endocrinol Metab. 2017 Jul;28(7):473-484. doi: 10.1016/j.tem.2017.03.001. Epub 2017 Apr 3. Review.

2.

The SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolism.

Harijan RK, Mazet M, Kiema TR, Bouyssou G, Alexson SE, Bergmann U, Moreau P, Michels PA, Bringaud F, Wierenga RK.

Proteins. 2016 Aug;84(8):1075-96. doi: 10.1002/prot.25054. Epub 2016 May 9.

PMID:
27093562
3.

Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice.

Skorve J, Hilvo M, Vihervaara T, Burri L, Bohov P, Tillander V, Bjørndal B, Suoniemi M, Laaksonen R, Ekroos K, Berge RK, Alexson SE.

Lipids Health Dis. 2015 Aug 11;14:88. doi: 10.1186/s12944-015-0086-2.

4.

Three differently generated salmon protein hydrolysates reveal opposite effects on hepatic lipid metabolism in mice fed a high-fat diet.

Vik R, Tillander V, Skorve J, Vihervaara T, Ekroos K, Alexson SE, Berge RK, Bjørndal B.

Food Chem. 2015 Sep 15;183:101-10. doi: 10.1016/j.foodchem.2015.03.011. Epub 2015 Mar 17.

5.

The crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase (T1): insight into the reaction mechanism of its thiolase and thioesterase activities.

Kiema TR, Harijan RK, Strozyk M, Fukao T, Alexson SE, Wierenga RK.

Acta Crystallogr D Biol Crystallogr. 2014 Dec 1;70(Pt 12):3212-25. doi: 10.1107/S1399004714023827. Epub 2014 Nov 22.

PMID:
25478839
6.

Fish oil and krill oil supplementations differentially regulate lipid catabolic and synthetic pathways in mice.

Tillander V, Bjørndal B, Burri L, Bohov P, Skorve J, Berge RK, Alexson SE.

Nutr Metab (Lond). 2014 Apr 27;11:20. doi: 10.1186/1743-7075-11-20. eCollection 2014.

7.

Regulation of peroxisomal lipid metabolism: the role of acyl-CoA and coenzyme A metabolizing enzymes.

Hunt MC, Tillander V, Alexson SE.

Biochimie. 2014 Mar;98:45-55. doi: 10.1016/j.biochi.2013.12.018. Epub 2014 Jan 2. Review.

PMID:
24389458
8.

Acyl-CoA thioesterase 9 (ACOT9) in mouse may provide a novel link between fatty acid and amino acid metabolism in mitochondria.

Tillander V, Arvidsson Nordström E, Reilly J, Strozyk M, Van Veldhoven PP, Hunt MC, Alexson SE.

Cell Mol Life Sci. 2014 Mar;71(5):933-48. doi: 10.1007/s00018-013-1422-1. Epub 2013 Jul 18.

PMID:
23864032
9.

Metabolic adaptation allows Amacr-deficient mice to remain symptom-free despite low levels of mature bile acids.

Selkälä EM, Kuusisto SM, Salonurmi T, Savolainen MJ, Jauhiainen M, Pirilä PL, Kvist AP, Conzelmann E, Schmitz W, Alexson SE, Kotti TJ, Hiltunen JK, Autio KJ.

Biochim Biophys Acta. 2013 Aug;1831(8):1335-43. doi: 10.1016/j.bbalip.2013.05.002. Epub 2013 May 13.

PMID:
23680781
10.

Pharmacological and Toxicological Advances in PPAR-Related Medicines.

Kamijo Y, Nicol CJ, Alexson SE.

PPAR Res. 2012;2012:940964. doi: 10.1155/2012/940964. Epub 2012 Oct 18. No abstract available.

11.

The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism.

Hunt MC, Siponen MI, Alexson SE.

Biochim Biophys Acta. 2012 Sep;1822(9):1397-410. doi: 10.1016/j.bbadis.2012.03.009. Epub 2012 Mar 23. Review.

12.

Localization of peroxisomal matrix proteins by photobleaching.

Buch C, Hunt MC, Alexson SE, Hallberg E.

Biochem Biophys Res Commun. 2009 Oct 16;388(2):355-9. doi: 10.1016/j.bbrc.2009.08.013. Epub 2009 Aug 8.

PMID:
19666004
13.

The nudix hydrolase 7 is an Acyl-CoA diphosphatase involved in regulating peroxisomal coenzyme A homeostasis.

Reilly SJ, Tillander V, Ofman R, Alexson SE, Hunt MC.

J Biochem. 2008 Nov;144(5):655-63. doi: 10.1093/jb/mvn114. Epub 2008 Sep 17.

PMID:
18799520
14.

Novel functions of acyl-CoA thioesterases and acyltransferases as auxiliary enzymes in peroxisomal lipid metabolism.

Hunt MC, Alexson SE.

Prog Lipid Res. 2008 Nov;47(6):405-21. doi: 10.1016/j.plipres.2008.05.001. Epub 2008 May 15. Review.

PMID:
18538142
15.
17.

PPARalpha is a key regulator of hepatic FGF21.

Lundåsen T, Hunt MC, Nilsson LM, Sanyal S, Angelin B, Alexson SE, Rudling M.

Biochem Biophys Res Commun. 2007 Aug 24;360(2):437-40. Epub 2007 Jun 21.

PMID:
17601491
18.

Alternative exon usage selectively determines both tissue distribution and subcellular localization of the acyl-CoA thioesterase 7 gene products.

Hunt MC, Greene S, Hultenby K, Svensson LT, Engberg S, Alexson SE.

Cell Mol Life Sci. 2007 Jun;64(12):1558-70.

PMID:
17514357
19.

Diabetes or peroxisome proliferator-activated receptor alpha agonist increases mitochondrial thioesterase I activity in heart.

King KL, Young ME, Kerner J, Huang H, O'Shea KM, Alexson SE, Hoppel CL, Stanley WC.

J Lipid Res. 2007 Jul;48(7):1511-7. Epub 2007 Apr 16.

20.

A peroxisomal acyltransferase in mouse identifies a novel pathway for taurine conjugation of fatty acids.

Reilly SJ, O'Shea EM, Andersson U, O'Byrne J, Alexson SE, Hunt MC.

FASEB J. 2007 Jan;21(1):99-107. Epub 2006 Nov 20.

PMID:
17116739
21.
22.

Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen.

Wood-Allum CA, Barber SC, Kirby J, Heath P, Holden H, Mead R, Higginbottom A, Allen S, Beaujeux T, Alexson SE, Ince PG, Shaw PJ.

Brain. 2006 Jul;129(Pt 7):1693-709. Epub 2006 May 15.

PMID:
16702190
23.

The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes.

Westin MA, Hunt MC, Alexson SE.

J Biol Chem. 2005 Nov 18;280(46):38125-32. Epub 2005 Aug 31.

24.

A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases.

Hunt MC, Yamada J, Maltais LJ, Wright MW, Podesta EJ, Alexson SE.

J Lipid Res. 2005 Sep;46(9):2029-32. Epub 2005 Jul 1.

25.

Thyroid-hormone effects on putative biochemical pathways involved in UCP3 activation in rat skeletal muscle mitochondria.

Silvestri E, Moreno M, Lombardi A, Ragni M, de Lange P, Alexson SE, Lanni A, Goglia F.

FEBS Lett. 2005 Mar 14;579(7):1639-45.

26.

The expression of cytosolic and mitochondrial type II acyl-CoA thioesterases is upregulated in the porcine corpus luteum during pregnancy.

Boström M, Alexson SE, Lundgren B, Nelson BD, DePierre JW.

Prostaglandins Leukot Essent Fatty Acids. 2004 Nov;71(5):319-27.

PMID:
15380819
27.

Differential regulation of cytosolic and peroxisomal bile acid amidation by PPAR alpha activation favors the formation of unconjugated bile acids.

Solaas K, Kase BF, Pham V, Bamberg K, Hunt MC, Alexson SE.

J Lipid Res. 2004 Jun;45(6):1051-60. Epub 2004 Mar 16.

28.
29.

Peroxisome proliferator-activated receptor alpha is not the exclusive mediator of the effects of dietary cyclic FA in mice.

Bretillon L, Alexson SE, Joffre F, Pasquis B, Sébédio JL.

Lipids. 2003 Sep;38(9):957-63.

PMID:
14584603
30.

The human bile acid-CoA:amino acid N-acyltransferase functions in the conjugation of fatty acids to glycine.

O'Byrne J, Hunt MC, Rai DK, Saeki M, Alexson SE.

J Biol Chem. 2003 Sep 5;278(36):34237-44. Epub 2003 Jun 16.

31.

Involvement of the peroxisome proliferator-activated receptor alpha in the immunomodulation caused by peroxisome proliferators in mice.

Yang Q, Xie Y, Alexson SE, Nelson BD, DePierre JW.

Biochem Pharmacol. 2002 May 15;63(10):1893-900.

PMID:
12034374
32.

Involvement of liver carboxylesterases in the in vitro metabolism of lidocaine.

Alexson SE, Diczfalusy M, Halldin M, Swedmark S.

Drug Metab Dispos. 2002 Jun;30(6):643-7.

PMID:
12019189
33.

The role Acyl-CoA thioesterases play in mediating intracellular lipid metabolism.

Hunt MC, Alexson SE.

Prog Lipid Res. 2002 Mar;41(2):99-130. Review.

PMID:
11755680
34.

The peroxisome proliferator-induced cytosolic type I acyl-CoA thioesterase (CTE-I) is a serine-histidine-aspartic acid alpha /beta hydrolase.

Huhtinen K, O'Byrne J, Lindquist PJ, Contreras JA, Alexson SE.

J Biol Chem. 2002 Feb 1;277(5):3424-32. Epub 2001 Nov 2.

35.

Characterization of an acyl-coA thioesterase that functions as a major regulator of peroxisomal lipid metabolism.

Hunt MC, Solaas K, Kase BF, Alexson SE.

J Biol Chem. 2002 Jan 11;277(2):1128-38. Epub 2001 Oct 22.

36.

Altered expression of the carboxylesterases ES-4 and ES-10 by peroxisome proliferator chemicals.

Poole M, Bridgers K, Alexson SE, Corton JC.

Toxicology. 2001 Aug 28;165(2-3):109-19.

PMID:
11522369
37.

Characterization of enzymes involved in formation of ethyl esters of long-chain fatty acids in humans.

Diczfalusy MA, Björkhem I, Einarsson C, Hillebrant CG, Alexson SE.

J Lipid Res. 2001 Jul;42(7):1025-32.

38.

Differential induction of peroxisomal populations in subcellular fractions of rat liver.

Wilcke M, Alexson SE.

Biochim Biophys Acta. 2001 Jan 12;1544(1-2):358-69.

PMID:
11341945
39.

Acyl-CoA thioesterases belong to a novel gene family of peroxisome proliferator-regulated enzymes involved in lipid metabolism.

Hunt MC, Lindquist PJ, Nousiainen S, Huttunen M, Orii K, Svensson TL, Aoyama T, Hashimoto T, Diczfalusy U, Alexson SE.

Cell Biochem Biophys. 2000;32 Spring:317-24.

PMID:
11330065
40.

Lipid regulation of gene expression.

Hunt MC, Alexson SE.

Biochem Soc Trans. 1999 Aug;27(4):378-82. No abstract available.

PMID:
10917606
41.

The peroxisome proliferator-activated receptor alpha (PPARalpha) regulates bile acid biosynthesis.

Hunt MC, Yang YZ, Eggertsen G, Carneheim CM, Gåfvels M, Einarsson C, Alexson SE.

J Biol Chem. 2000 Sep 15;275(37):28947-53.

42.

Involvement of the peroxisome proliferator-activated receptor alpha in regulating long-chain acyl-CoA thioesterases.

Hunt MC, Lindquist PJ, Peters JM, Gonzalez FJ, Diczfalusy U, Alexson SE.

J Lipid Res. 2000 May;41(5):814-23.

43.

Cloning and regulation of peroxisome proliferator-induced acyl-CoA thioesterases from mouse liver.

Hunt M, Lindquist PJ, Nousiainen S, Svensson TL, Diczfalusy U, Alexson SE.

Adv Exp Med Biol. 1999;466:195-200.

PMID:
10709644
44.

Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism.

Hunt MC, Nousiainen SE, Huttunen MK, Orii KE, Svensson LT, Alexson SE.

J Biol Chem. 1999 Nov 26;274(48):34317-26.

45.

Rat peroxisome proliferator-activated receptors and brown adipose tissue function during cold acclimatization.

Guardiola-Diaz HM, Rehnmark S, Usuda N, Albrektsen T, Feltkamp D, Gustafsson JA, Alexson SE.

J Biol Chem. 1999 Aug 13;274(33):23368-77.

46.

Microsomal long-chain acyl-CoA thioesterase (carboxylesterase ES-4) is regulated by thyroxine.

Diczfalusy MA, Andersson U, Björkhem I, Einarsson C, Alexson SE.

Biochim Biophys Acta. 1999 Jul 9;1439(1):40-6.

PMID:
10395963
47.

Formation of fatty acid ethyl esters in rat liver microsomes. Evidence for a key role for acyl-CoA: ethanol O-acyltransferase.

Diczfalusy MA, Björkhem I, Einarsson C, Alexson SE.

Eur J Biochem. 1999 Jan;259(1-2):404-11.

49.

Molecular cloning and characterization of a mitochondrial peroxisome proliferator-induced acyl-CoA thioesterase from rat liver.

Svensson LT, Engberg ST, Aoyama T, Usuda N, Alexson SE, Hashimoto T.

Biochem J. 1998 Feb 1;329 ( Pt 3):601-8.

50.

Isolation of carboxylester lipase (CEL) isoenzymes from Candida rugosa and identification of the corresponding genes.

Diczfalusy MA, Hellman U, Alexson SE.

Arch Biochem Biophys. 1997 Dec 1;348(1):1-8.

PMID:
9390168

Supplemental Content

Loading ...
Support Center