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Items: 36

1.

Synthesis of Hydroxyapatite, β-Tricalcium Phosphate and Biphasic Calcium Phosphate Particles to Act as Local Delivery Carriers of Curcumin: Loading, Release and In Vitro Studies.

Xidaki D, Agrafioti P, Diomatari D, Kaminari A, Tsalavoutas-Psarras E, Alexiou P, Psycharis V, Tsilibary EC, Silvestros S, Sagnou M.

Materials (Basel). 2018 Apr 12;11(4). pii: E595. doi: 10.3390/ma11040595.

2.

Ribothrypsis, a novel process of canonical mRNA decay, mediates ribosome-phased mRNA endonucleolysis.

Ibrahim F, Maragkakis M, Alexiou P, Mourelatos Z.

Nat Struct Mol Biol. 2018 Apr;25(4):302-310. doi: 10.1038/s41594-018-0042-8. Epub 2018 Mar 5.

3.

cCLIP-Seq: Retrieval of Chimeric Reads from HITS-CLIP (CLIP-Seq) Libraries.

Alexiou P, Maragkakis M, Mourelatos Z, Vourekas A.

Methods Mol Biol. 2018;1680:87-100. doi: 10.1007/978-1-4939-7339-2_6.

PMID:
29030843
4.

Aqueous Solubility Enhancement for Bioassays of Insoluble Inhibitors and QSPR Analysis: A TNF-α Study.

Mettou A, Papaneophytou C, Melagraki G, Maranti A, Liepouri F, Alexiou P, Papakyriakou A, Couladouros E, Eliopoulos E, Afantitis A, Kontopidis G.

SLAS Discov. 2018 Jan;23(1):84-93. doi: 10.1177/2472555217712507. Epub 2017 Jun 6.

PMID:
28586633
5.

Kc167, a widely used Drosophila cell line, contains an active primary piRNA pathway.

Vrettos N, Maragkakis M, Alexiou P, Mourelatos Z.

RNA. 2017 Jan;23(1):108-118. Epub 2016 Oct 27.

6.

Sequence-dependent but not sequence-specific piRNA adhesion traps mRNAs to the germ plasm.

Vourekas A, Alexiou P, Vrettos N, Maragkakis M, Mourelatos Z.

Nature. 2016 Mar 17;531(7594):390-394. doi: 10.1038/nature17150. Epub 2016 Mar 7.

7.

CLIPSeqTools--a novel bioinformatics CLIP-seq analysis suite.

Maragkakis M, Alexiou P, Nakaya T, Mourelatos Z.

RNA. 2016 Jan;22(1):1-9. doi: 10.1261/rna.052167.115. Epub 2015 Nov 17.

8.

The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing.

Vourekas A, Zheng K, Fu Q, Maragkakis M, Alexiou P, Ma J, Pillai RS, Mourelatos Z, Wang PJ.

Genes Dev. 2015 Mar 15;29(6):617-29. doi: 10.1101/gad.254631.114. Epub 2015 Mar 11.

9.

A MicroRNA precursor surveillance system in quality control of MicroRNA synthesis.

Liu X, Zheng Q, Vrettos N, Maragkakis M, Alexiou P, Gregory BD, Mourelatos Z.

Mol Cell. 2014 Sep 18;55(6):868-879. doi: 10.1016/j.molcel.2014.07.017. Epub 2014 Aug 28.

10.

Rationally designed less toxic SPD-304 analogs and preliminary evaluation of their TNF inhibitory effects.

Alexiou P, Papakyriakou A, Ntougkos E, Papaneophytou CP, Liepouri F, Mettou A, Katsoulis I, Maranti A, Tsiliouka K, Strongilos A, Chaitidou S, Douni E, Kontopidis G, Kollias G, Couladouros E, Eliopoulos E.

Arch Pharm (Weinheim). 2014 Nov;347(11):798-805. doi: 10.1002/ardp.201400198. Epub 2014 Aug 27.

PMID:
25160057
11.

Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit morphine's rewarding effect in rats.

Katsidoni V, Alexiou P, Fotiadou M, Pelecanou M, Sagnou M, Panagis G.

Psychopharmacology (Berl). 2014 Dec;231(23):4467-78. doi: 10.1007/s00213-014-3603-5. Epub 2014 May 17.

PMID:
24838368
12.

Mitochondrial protein BmPAPI modulates the length of mature piRNAs.

Honda S, Kirino Y, Maragkakis M, Alexiou P, Ohtaki A, Murali R, Mourelatos Z, Kirino Y.

RNA. 2013 Oct;19(10):1405-18. doi: 10.1261/rna.040428.113. Epub 2013 Aug 22.

13.

Identification of in vivo, conserved, TAF15 RNA binding sites reveals the impact of TAF15 on the neuronal transcriptome.

Ibrahim F, Maragkakis M, Alexiou P, Maronski MA, Dichter MA, Mourelatos Z.

Cell Rep. 2013 Feb 21;3(2):301-8. doi: 10.1016/j.celrep.2013.01.021. Epub 2013 Feb 14.

14.

FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns.

Nakaya T, Alexiou P, Maragkakis M, Chang A, Mourelatos Z.

RNA. 2013 Apr;19(4):498-509. doi: 10.1261/rna.037804.112. Epub 2013 Feb 6.

15.

Novel aldose reductase inhibitors: a patent survey (2006--present).

Chatzopoulou M, Alexiou P, Kotsampasakou E, Demopoulos VJ.

Expert Opin Ther Pat. 2012 Nov;22(11):1303-23. doi: 10.1517/13543776.2012.726615. Epub 2012 Sep 24. Review.

PMID:
22998509
16.

Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis.

Vourekas A, Zheng Q, Alexiou P, Maragkakis M, Kirino Y, Gregory BD, Mourelatos Z.

Nat Struct Mol Biol. 2012 Aug;19(8):773-81. doi: 10.1038/nsmb.2347. Epub 2012 Jul 29.

17.

Accurate microRNA Target Prediction Using Detailed Binding Site Accessibility and Machine Learning on Proteomics Data.

Reczko M, Maragkakis M, Alexiou P, Papadopoulos GL, Hatzigeorgiou AG.

Front Genet. 2012 Jan 18;2:103. doi: 10.3389/fgene.2011.00103. eCollection 2011.

18.

Functional microRNA targets in protein coding sequences.

Reczko M, Maragkakis M, Alexiou P, Grosse I, Hatzigeorgiou AG.

Bioinformatics. 2012 Mar 15;28(6):771-6. doi: 10.1093/bioinformatics/bts043. Epub 2012 Jan 27.

PMID:
22285563
19.

TarBase 6.0: capturing the exponential growth of miRNA targets with experimental support.

Vergoulis T, Vlachos IS, Alexiou P, Georgakilas G, Maragkakis M, Reczko M, Gerangelos S, Koziris N, Dalamagas T, Hatzigeorgiou AG.

Nucleic Acids Res. 2012 Jan;40(Database issue):D222-9. doi: 10.1093/nar/gkr1161. Epub 2011 Dec 1.

20.

DIANA-microT Web server upgrade supports Fly and Worm miRNA target prediction and bibliographic miRNA to disease association.

Maragkakis M, Vergoulis T, Alexiou P, Reczko M, Plomaritou K, Gousis M, Kourtis K, Koziris N, Dalamagas T, Hatzigeorgiou AG.

Nucleic Acids Res. 2011 Jul;39(Web Server issue):W145-8. doi: 10.1093/nar/gkr294. Epub 2011 May 6.

21.

In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection.

Marotta D, Karar J, Jenkins WT, Kumanova M, Jenkins KW, Tobias JW, Baldwin D, Hatzigeorgiou A, Alexiou P, Evans SM, Alarcon R, Maity A, Koch C, Koumenis C.

Cancer Res. 2011 Feb 1;71(3):779-89. doi: 10.1158/0008-5472.CAN-10-3061. Epub 2011 Jan 25.

22.
23.

RAGE: a multi-ligand receptor unveiling novel insights in health and disease.

Alexiou P, Chatzopoulou M, Pegklidou K, Demopoulos VJ.

Curr Med Chem. 2010;17(21):2232-52. Review.

PMID:
20459381
24.

The DIANA-mirExTra web server: from gene expression data to microRNA function.

Alexiou P, Maragkakis M, Papadopoulos GL, Simmosis VA, Zhang L, Hatzigeorgiou AG.

PLoS One. 2010 Feb 11;5(2):e9171. doi: 10.1371/journal.pone.0009171.

25.

miRGen 2.0: a database of microRNA genomic information and regulation.

Alexiou P, Vergoulis T, Gleditzsch M, Prekas G, Dalamagas T, Megraw M, Grosse I, Sellis T, Hatzigeorgiou AG.

Nucleic Acids Res. 2010 Jan;38(Database issue):D137-41. doi: 10.1093/nar/gkp888. Epub 2009 Oct 22.

26.

Lost in translation: an assessment and perspective for computational microRNA target identification.

Alexiou P, Maragkakis M, Papadopoulos GL, Reczko M, Hatzigeorgiou AG.

Bioinformatics. 2009 Dec 1;25(23):3049-55. doi: 10.1093/bioinformatics/btp565. Epub 2009 Sep 29. Review.

PMID:
19789267
27.

Accurate microRNA target prediction correlates with protein repression levels.

Maragkakis M, Alexiou P, Papadopoulos GL, Reczko M, Dalamagas T, Giannopoulos G, Goumas G, Koukis E, Kourtis K, Simossis VA, Sethupathy P, Vergoulis T, Koziris N, Sellis T, Tsanakas P, Hatzigeorgiou AG.

BMC Bioinformatics. 2009 Sep 18;10:295. doi: 10.1186/1471-2105-10-295.

28.

DIANA-mirPath: Integrating human and mouse microRNAs in pathways.

Papadopoulos GL, Alexiou P, Maragkakis M, Reczko M, Hatzigeorgiou AG.

Bioinformatics. 2009 Aug 1;25(15):1991-3. doi: 10.1093/bioinformatics/btp299. Epub 2009 May 12.

PMID:
19435746
29.

DIANA-microT web server: elucidating microRNA functions through target prediction.

Maragkakis M, Reczko M, Simossis VA, Alexiou P, Papadopoulos GL, Dalamagas T, Giannopoulos G, Goumas G, Koukis E, Kourtis K, Vergoulis T, Koziris N, Sellis T, Tsanakas P, Hatzigeorgiou AG.

Nucleic Acids Res. 2009 Jul;37(Web Server issue):W273-6. doi: 10.1093/nar/gkp292. Epub 2009 Apr 30.

30.

Aldose reductase enzyme and its implication to major health problems of the 21(st) century.

Alexiou P, Pegklidou K, Chatzopoulou M, Nicolaou I, Demopoulos VJ.

Curr Med Chem. 2009;16(6):734-52. Review.

PMID:
19199934
32.

Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer.

Zhang L, Volinia S, Bonome T, Calin GA, Greshock J, Yang N, Liu CG, Giannakakis A, Alexiou P, Hasegawa K, Johnstone CN, Megraw MS, Adams S, Lassus H, Huang J, Kaur S, Liang S, Sethupathy P, Leminen A, Simossis VA, Sandaltzopoulos R, Naomoto Y, Katsaros D, Gimotty PA, DeMichele A, Huang Q, Bützow R, Rustgi AK, Weber BL, Birrer MJ, Hatzigeorgiou AG, Croce CM, Coukos G.

Proc Natl Acad Sci U S A. 2008 May 13;105(19):7004-9. doi: 10.1073/pnas.0801615105. Epub 2008 May 5.

33.

Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors.

Alexiou P, Nicolaou I, Stefek M, Kristl A, Demopoulos VJ.

Bioorg Med Chem. 2008 Apr 1;16(7):3926-32. doi: 10.1016/j.bmc.2008.01.042. Epub 2008 Jan 30.

PMID:
18267362
34.

Effect of sulphasalazine in patients with juvenile chronic arthritis (JCA).

Settas L, Alexiou P, Dimitriadis G, Mata-Tsi E, Souliou E, Papapanagiotou J, Tourkantonis A.

Acta Univ Carol Med (Praha). 1991;37(1-2):76-9. No abstract available.

PMID:
1688267
35.

Pharmacokinetics of aztreonam administered i.p. in continuous ambulatory peritoneal dialysis (CAPD) patients.

Nikolaidis P, Dombros N, Alexiou P, Balaskas E, Tourkantonis A.

Perit Dial Int. 1989;9(1):57-9.

PMID:
2488183
36.

Clinical experience with aztreonam in the treatment of nosocomial infections.

Nikolaidis P, Alexiou P, Tourkantonis A.

Chemioterapia. 1987 Jun;6(2 Suppl):379. No abstract available.

PMID:
3509451

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