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Items: 19

1.

Human β-defensin 4 - defensin without the "twist".

Prahl A, Pazgier M, Alexandratos J, Lubkowski J.

Postepy Biochem. 2016;62(3):349-361.

2.

Localization of ASV integrase-DNA contacts by site-directed crosslinking and their structural analysis.

Peletskaya E, Andrake M, Gustchina A, Merkel G, Alexandratos J, Zhou D, Bojja RS, Satoh T, Potapov M, Kogon A, Potapov V, Wlodawer A, Skalka AM.

PLoS One. 2011;6(12):e27751. doi: 10.1371/journal.pone.0027751. Epub 2011 Dec 1.

3.

Piecing together the structure of retroviral integrase, an important target in AIDS therapy.

Jaskolski M, Alexandratos JN, Bujacz G, Wlodawer A.

FEBS J. 2009 Jun;276(11):2926-46. doi: 10.1111/j.1742-4658.2009.07009.x. Epub 2009 Apr 14. Review.

4.

Crystal structure of a dimerized cockroach allergen Bla g 2 complexed with a monoclonal antibody.

Li M, Gustchina A, Alexandratos J, Wlodawer A, Wünschmann S, Kepley CL, Chapman MD, Pomés A.

J Biol Chem. 2008 Aug 15;283(33):22806-14. doi: 10.1074/jbc.M800937200. Epub 2008 Jun 2.

5.

Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics.

Blaszczyk J, Li Y, Cherry S, Alexandratos J, Wu Y, Shaw G, Tropea JE, Waugh DS, Yan H, Ji X.

Acta Crystallogr D Biol Crystallogr. 2007 Nov;63(Pt 11):1169-77. Epub 2007 Oct 17.

PMID:
18007032
6.

Interactions between HIV-1 Gag molecules in solution: an inositol phosphate-mediated switch.

Datta SA, Zhao Z, Clark PK, Tarasov S, Alexandratos JN, Campbell SJ, Kvaratskhelia M, Lebowitz J, Rein A.

J Mol Biol. 2007 Jan 19;365(3):799-811. Epub 2006 Oct 26.

7.

Crystal structure of human T cell leukemia virus protease, a novel target for anticancer drug design.

Li M, Laco GS, Jaskolski M, Rozycki J, Alexandratos J, Wlodawer A, Gustchina A.

Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18332-7. Epub 2005 Dec 13.

8.

1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors.

Brik A, Alexandratos J, Lin YC, Elder JH, Olson AJ, Wlodawer A, Goodsell DS, Wong CH.

Chembiochem. 2005 Jul;6(7):1167-9. No abstract available.

PMID:
15934050
9.

Integrase of Mason-Pfizer monkey virus.

Snásel J, Krejcík Z, Jencová V, Rosenberg I, Ruml T, Alexandratos J, Gustchina A, Pichová I.

FEBS J. 2005 Jan;272(1):203-16.

10.

Total chemical synthesis of N-myristoylated HIV-1 matrix protein p17: structural and mechanistic implications of p17 myristoylation.

Wu Z, Alexandratos J, Ericksen B, Lubkowski J, Gallo RC, Lu W.

Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11587-92. Epub 2004 Jul 27.

12.

Atomic Resolution Structures of the Core Domain of Avian Sarcoma Virus Integrase and Its D64N Mutant.

Lubkowski J, Dauter Z, Yang F, Alexandratos J, Merkel G, Skalka AM, Wlodawer A.

Biochemistry. 1999 Nov 9;38(45):15060. No abstract available.

PMID:
10555989
13.

Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant.

Lubkowski J, Dauter Z, Yang F, Alexandratos J, Merkel G, Skalka AM, Wlodawer A.

Biochemistry. 1999 Oct 12;38(41):13512-22. Erratum in: Biochemistry 1999 Nov 9;38(45):15060.

PMID:
10521258
14.

Structural basis for inactivating mutations and pH-dependent activity of avian sarcoma virus integrase.

Lubkowski J, Yang F, Alexandratos J, Merkel G, Katz RA, Gravuer K, Skalka AM, Wlodawer A.

J Biol Chem. 1998 Dec 4;273(49):32685-9.

15.

Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor.

Lubkowski J, Yang F, Alexandratos J, Wlodawer A, Zhao H, Burke TR Jr, Neamati N, Pommier Y, Merkel G, Skalka AM.

Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):4831-6.

16.

Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity.

Bujacz G, Alexandratos J, Wlodawer A, Merkel G, Andrake M, Katz RA, Skalka AM.

J Biol Chem. 1997 Jul 18;272(29):18161-8.

17.

The catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutant.

Bujacz G, Alexandratos J, Qing ZL, Clément-Mella C, Wlodawer A.

FEBS Lett. 1996 Dec 2;398(2-3):175-8.

18.

The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations.

Bujacz G, Jaskólski M, Alexandratos J, Wlodawer A, Merkel G, Katz RA, Skalka AM.

Structure. 1996 Jan 15;4(1):89-96.

19.

High-resolution structure of the catalytic domain of avian sarcoma virus integrase.

Bujacz G, Jaskólski M, Alexandratos J, Wlodawer A, Merkel G, Katz RA, Skalka AM.

J Mol Biol. 1995 Oct 20;253(2):333-46.

PMID:
7563093

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