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Features of repeated muscle biopsies and phenotypes of monocytes in paired blood samples and clinical long-term response to treatment in patients with idiopathic inflammatory myopathy: a pilot study.

Tang Q, Gheorghe KR, Zhang XM, Lindroos E, Alexanderson H, Wick C, Bruton M, Fernandes-Cerqueira C, Harris RA, Nennesmo I, Lundberg IE.

Clin Exp Rheumatol. 2019 May 22. [Epub ahead of print]


Mitochondrial dysfunction and role of harakiri in the pathogenesis of myositis.

Boehler JF, Horn A, Novak J, Li N, Ghimbovschi S, Lundberg IE, Alexanderson H, Munters LA, Jaiswal JK, Nagaraju K.

J Pathol. 2019 May 28. doi: 10.1002/path.5309. [Epub ahead of print]


Widespread global peatland establishment and persistence over the last 130,000 y.

Treat CC, Kleinen T, Broothaerts N, Dalton AS, Dommain R, Douglas TA, Drexler JZ, Finkelstein SA, Grosse G, Hope G, Hutchings J, Jones MC, Kuhry P, Lacourse T, Lähteenoja O, Loisel J, Notebaert B, Payne RJ, Peteet DM, Sannel ABK, Stelling JM, Strauss J, Swindles GT, Talbot J, Tarnocai C, Verstraeten G, Williams CJ, Xia Z, Yu Z, Väliranta M, Hättestrand M, Alexanderson H, Brovkin V.

Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4822-4827. doi: 10.1073/pnas.1813305116. Epub 2019 Feb 25.


OMERACT 2018 Modified Patient-reported Outcome Domain Core Set in the Life Impact Area for Adult Idiopathic Inflammatory Myopathies.

Regardt M, Mecoli CA, Park JK, de Groot I, Sarver C, Needham M, de Visser M, Shea B, Bingham CO III, Lundberg IE, Song YW, Christopher-Stine L, Alexanderson H.

J Rheumatol. 2019 Feb 15. pii: jrheum.181065. doi: 10.3899/jrheum.181065. [Epub ahead of print]


Comparison of autoantibody specificities tested by a line blot assay and immunoprecipitation-based algorithm in patients with idiopathic inflammatory myopathies.

Espinosa-Ortega F, Holmqvist M, Alexanderson H, Storfors H, Mimori T, Lundberg IE, Rönnelid J.

Ann Rheum Dis. 2019 Jun;78(6):858-860. doi: 10.1136/annrheumdis-2018-214690. Epub 2019 Feb 13. No abstract available.


Exercise in Myositis.

Alexanderson H.

Curr Treatm Opt Rheumatol. 2018;4(4):289-298. doi: 10.1007/s40674-018-0113-3. Epub 2018 Nov 23. Review.


Effect of CTLA4-Ig (abatacept) treatment on T cells and B cells in peripheral blood of patients with polymyositis and dermatomyositis.

Tang Q, Ramsköld D, Krystufkova O, Mann HF, Wick C, Dastmalchi M, Lakshmikanth T, Chen Y, Mikes J, Alexanderson H, Achour A, Brodin P, Vencovsky J, Lundberg IE, Malmström V.

Scand J Immunol. 2019 Jan;89(1):e12732. doi: 10.1111/sji.12732. Epub 2018 Dec 9.


Perceptions of Patients, Caregivers, and Healthcare Providers of Idiopathic Inflammatory Myopathies: An International OMERACT Study.

Mecoli CA, Park JK, Alexanderson H, Regardt M, Needham M, de Groot I, Sarver C, Lundberg IE, Shea B, de Visser M, Song YW, Bingham CO 3rd, Christopher-Stine L.

J Rheumatol. 2019 Jan;46(1):106-111. doi: 10.3899/jrheum.180353. Epub 2018 Sep 15.


Muscle endurance, strength, and active range of motion in patients with different subphenotypes in systemic sclerosis: a cross-sectional cohort study.

Pettersson H, Boström C, Bringby F, Walle-Hansen R, Jacobsson L, Svenungsson E, Nordin A, Alexanderson H.

Scand J Rheumatol. 2019 Mar;48(2):141-148. doi: 10.1080/03009742.2018.1477990. Epub 2018 Aug 2.


Advancing the Development of Patient-reported Outcomes for Adult Myositis at OMERACT 2016: An International Delphi Study.

Park JK, Mecoli CA, Alexanderson H, Regardt M, Christopher-Stine L, Casal-Domínguez M, de Groot I, Sarver C, Lundberg IE, Bingham CO 3rd, Song YW.

J Rheumatol. 2018 Jul;45(7):1071. doi: 10.3899/jrheum.161252.C2. No abstract available.


Targeted lipidomics analysis identified altered serum lipid profiles in patients with polymyositis and dermatomyositis.

Raouf J, Idborg H, Englund P, Alexanderson H, Dastmalchi M, Jakobsson PJ, Lundberg IE, Korotkova M.

Arthritis Res Ther. 2018 May 2;20(1):83. doi: 10.1186/s13075-018-1579-y.


Muscle Strength and Muscle Endurance During the First Year of Treatment of Polymyositis and Dermatomyositis: A Prospective Study.

Alexanderson H, Regardt M, Ottosson C, Alemo Munters L, Dastmalchi M, Dani L, Lundberg IE.

J Rheumatol. 2018 Apr;45(4):538-546. doi: 10.3899/jrheum.161183. Epub 2018 Feb 1.


Advancing the Development of Patient-reported Outcomes for Adult Myositis at OMERACT 2016: An International Delphi Study.

Park JK, Mecoli CA, Alexanderson H, Regardt M, Christopher-Stine L, Casal-Domínguez M, de Groot I, Sarver C, Lundberg IE, Bingham CO 3rd, Song YW.

J Rheumatol. 2017 Dec;44(12):1944. doi: 10.3899/jrheum.161252.C1. No abstract available.


Abatacept in the treatment of adult dermatomyositis and polymyositis: a randomised, phase IIb treatment delayed-start trial.

Tjärnlund A, Tang Q, Wick C, Dastmalchi M, Mann H, Tomasová Studýnková J, Chura R, Gullick NJ, Salerno R, Rönnelid J, Alexanderson H, Lindroos E, Aggarwal R, Gordon P, Vencovsky J, Lundberg IE.

Ann Rheum Dis. 2018 Jan;77(1):55-62. doi: 10.1136/annrheumdis-2017-211751. Epub 2017 Oct 9.


Effect of endurance exercise on microRNAs in myositis skeletal muscle-A randomized controlled study.

Boehler JF, Hogarth MW, Barberio MD, Novak JS, Ghimbovschi S, Brown KJ, Alemo Munters L, Loell I, Chen YW, Gordish-Dressman H, Alexanderson H, Lundberg IE, Nagaraju K.

PLoS One. 2017 Aug 22;12(8):e0183292. doi: 10.1371/journal.pone.0183292. eCollection 2017.


Novel insights of disability assessment in adult myositis.

Espinosa-Ortega HF, Moreno-Ramirez M, Alexanderson H.

Curr Opin Rheumatol. 2017 Nov;29(6):591-597. doi: 10.1097/BOR.0000000000000433. Review.


Advancing the Development of Patient-reported Outcomes for Adult Myositis at OMERACT 2016: An International Delphi Study.

Park JK, Mecoli CA, Alexanderson H, Regardt M, Christopher-Stine L, Casal-Domínguez M, de Groot I, Sarver C, Lundberg IE, Bingham CO 3rd, Song YW.

J Rheumatol. 2017 Nov;44(11):1683-1687. doi: 10.3899/jrheum.161252. Epub 2017 Aug 1. Erratum in: J Rheumatol. 2017 Dec;44(12 ):1944. J Rheumatol. 2018 Jul;45(7):1071.


Quality of life correlates with muscle strength in patients with dermato- or polymyositis.

Poulsen KB, Alexanderson H, Dalgård C, Jacobsen S, Weile L, Diederichsen LP.

Clin Rheumatol. 2017 Oct;36(10):2289-2295. doi: 10.1007/s10067-017-3706-6. Epub 2017 Jun 6.


Aerobic and resistance exercise in systemic sclerosis: State of the art.

de Oliveira NC, Portes LA, Pettersson H, Alexanderson H, Boström C.

Musculoskeletal Care. 2017 Dec;15(4):316-323. doi: 10.1002/msc.1185. Epub 2017 Apr 5. Review.


Self-reported physical capacity and activity in patients with systemic sclerosis and matched controls.

Pettersson H, Åkerström A, Nordin A, Svenungsson E, Alexanderson H, Boström C.

Scand J Rheumatol. 2017 Nov;46(6):490-495. doi: 10.1080/03009742.2017.1281436. Epub 2017 Mar 17.


The host defense peptide LL-37 a possible inducer of the type I interferon system in patients with polymyositis and dermatomyositis.

Lu X, Tang Q, Lindh M, Dastmalchi M, Alexanderson H, Popovic Silwerfeldt K, Agerberth B, Lundberg IE, Wick C.

J Autoimmun. 2017 Mar;78:46-56. doi: 10.1016/j.jaut.2016.12.003. Epub 2016 Dec 22.


Effects on muscle tissue remodeling and lipid metabolism in muscle tissue from adult patients with polymyositis or dermatomyositis treated with immunosuppressive agents.

Loell I, Raouf J, Chen YW, Shi R, Nennesmo I, Alexanderson H, Dastmalchi M, Nagaraju K, Korotkova M, Lundberg IE.

Arthritis Res Ther. 2016 Jun 10;18(1):136. doi: 10.1186/s13075-016-1033-y.


Effects of conventional immunosuppressive treatment on CD244+ (CD28null) and FOXP3+ T cells in the inflamed muscle of patients with polymyositis and dermatomyositis.

Pandya JM, Loell I, Hossain MS, Zong M, Alexanderson H, Raghavan S, Lundberg IE, Malmström V.

Arthritis Res Ther. 2016 Apr 1;18:80. doi: 10.1186/s13075-016-0974-5.


Endurance Exercise Improves Molecular Pathways of Aerobic Metabolism in Patients With Myositis.

Munters LA, Loell I, Ossipova E, Raouf J, Dastmalchi M, Lindroos E, Chen YW, Esbjörnsson M, Korotkova M, Alexanderson H, Nagaraju K, Crofford LJ, Jakobsson PJ, Lundberg IE.

Arthritis Rheumatol. 2016 Jul;68(7):1738-50. doi: 10.1002/art.39624.


Physical exercise as a treatment for adult and juvenile myositis.

Alexanderson H.

J Intern Med. 2016 Jul;280(1):75-96. doi: 10.1111/joim.12481. Epub 2016 Feb 8. Review.


Proposal for a Candidate Core Set of Fitness and Strength Tests for Patients with Childhood or Adult Idiopathic Inflammatory Myopathies.

van der Stap DK, Rider LG, Alexanderson H, Huber AM, Gualano B, Gordon P, van der Net J, Mathiesen P, Johnson LG, Ernste FC, Feldman BM, Houghton KM, Singh-Grewal D, Kutzbach AG, Alemo Munters L, Takken T; International Myositis Assessment and Clinical Studies Group.

J Rheumatol. 2016 Jan;43(1):169-76. doi: 10.3899/jrheum.150270. Epub 2015 Nov 15. Review.


Patients' Experience of Myositis and Further Validation of a Myositis-specific Patient Reported Outcome Measure - Establishing Core Domains and Expanding Patient Input on Clinical Assessment in Myositis. Report from OMERACT 12.

Regardt M, Basharat P, Christopher-Stine L, Sarver C, Björn A, Lundberg IE, Wook Song Y, Bingham CO 3rd, Alexanderson H.

J Rheumatol. 2015 Dec;42(12):2492-5. doi: 10.3899/jrheum.141243. Epub 2015 May 1.


Therapy of myositis: biological and physical.

Lundberg IE, Vencovsky J, Alexanderson H.

Curr Opin Rheumatol. 2014 Nov;26(6):704-11. doi: 10.1097/BOR.0000000000000109. Review.


New insights into the benefits of exercise for muscle health in patients with idiopathic inflammatory myositis.

Alemo Munters L, Alexanderson H, Crofford LJ, Lundberg IE.

Curr Rheumatol Rep. 2014 Jul;16(7):429. doi: 10.1007/s11926-014-0429-4. Review.


Resistive home exercise in patients with recent-onset polymyositis and dermatomyositis -- a randomized controlled single-blinded study with a 2-year followup.

Alexanderson H, Munters LA, Dastmalchi M, Loell I, Heimbürger M, Opava CH, Lundberg IE.

J Rheumatol. 2014 Jun;41(6):1124-32. doi: 10.3899/jrheum.131145. Epub 2014 May 1.


Shallow hydrostratigraphy in an arsenic affected region of Bengal Basin: implication for targeting safe aquifers for drinking water supply.

Biswas A, Bhattacharya P, Mukherjee A, Nath B, Alexanderson H, Kundu AK, Chatterjee D, Jacks G.

Sci Total Environ. 2014 Jul 1;485-486:12-22. doi: 10.1016/j.scitotenv.2014.03.045. Epub 2014 Apr 1.


Hand exercise intervention in patients with polymyositis and dermatomyositis: a pilot study.

Regardt M, Schult ML, Axelsson Y, Aldehag A, Alexanderson H, Lundberg IE, Henriksson EW.

Musculoskeletal Care. 2014 Sep;12(3):160-72. doi: 10.1002/msc.1069. Epub 2014 Mar 12.


Intensive aerobic and muscle endurance exercise in patients with systemic sclerosis: a pilot study.

Alexanderson H, Bergegård J, Björnådal L, Nordin A.

BMC Res Notes. 2014 Feb 7;7:86. doi: 10.1186/1756-0500-7-86.


Patient-reported outcomes and adult patients' disease experience in the idiopathic inflammatory myopathies. report from the OMERACT 11 Myositis Special Interest Group.

Alexanderson H, Del Grande M, Bingham CO 3rd, Orbai AM, Sarver C, Clegg-Smith K, Lundberg IE, Song YW, Christopher-Stine L.

J Rheumatol. 2014 Mar;41(3):581-92. doi: 10.3899/jrheum.131247. Epub 2014 Jan 15. Review.


Disabilities of importance for patients to improve--using a patient preference tool in rheumatoid arthritis.

Alemo Munters L, Brodin N, Löfberg E, Stråt S, Alexanderson H.

Disabil Rehabil. 2014;36(21):1762-7. doi: 10.3109/09638288.2013.868535. Epub 2013 Dec 24.


Improved exercise performance and increased aerobic capacity after endurance training of patients with stable polymyositis and dermatomyositis.

Alemo Munters L, Dastmalchi M, Katz A, Esbjörnsson M, Loell I, Hanna B, Lidén M, Westerblad H, Lundberg IE, Alexanderson H.

Arthritis Res Ther. 2013 Aug 13;15(4):R83. doi: 10.1186/ar4263.


Improvement in health and possible reduction in disease activity using endurance exercise in patients with established polymyositis and dermatomyositis: a multicenter randomized controlled trial with a 1-year open extension followup.

Alemo Munters L, Dastmalchi M, Andgren V, Emilson C, Bergegård J, Regardt M, Johansson A, Orefelt Tholander I, Hanna B, Lidén M, Esbjörnsson M, Alexanderson H.

Arthritis Care Res (Hoboken). 2013 Dec;65(12):1959-68. doi: 10.1002/acr.22068.


Anakinra treatment in patients with refractory inflammatory myopathies and possible predictive response biomarkers: a mechanistic study with 12 months follow-up.

Zong M, Dorph C, Dastmalchi M, Alexanderson H, Pieper J, Amoudruz P, Barbasso Helmers S, Nennesmo I, Malmström V, Lundberg IE.

Ann Rheum Dis. 2014 May;73(5):913-20. doi: 10.1136/annrheumdis-2012-202857. Epub 2013 Apr 26.


TLR4 as receptor for HMGB1 induced muscle dysfunction in myositis.

Zong M, Bruton JD, Grundtman C, Yang H, Li JH, Alexanderson H, Palmblad K, Andersson U, Harris HE, Lundberg IE, Westerblad H.

Ann Rheum Dis. 2013 Aug;72(8):1390-9. doi: 10.1136/annrheumdis-2012-202207. Epub 2012 Nov 12.


The Myositis Activities Profile -- initial validation for assessment of polymyositis/dermatomyositis in the USA.

Alexanderson H, Reed AM, Ytterberg SR.

J Rheumatol. 2012 Nov;39(11):2134-41. doi: 10.3899/jrheum.120504. Epub 2012 Sep 1.


Activated LTB4 pathway in muscle tissue of patients with polymyositis or dermatomyositis.

Loell I, Alemo Munters L, Pandya J, Zong M, Alexanderson H, Fasth AE, Ståhl Hallengren C, Rådmark O, Lundberg IE, Jakobsson PJ, Korotkova M.

Ann Rheum Dis. 2013 Feb;72(2):293-9. doi: 10.1136/annrheumdis-2012-201294. Epub 2012 Jun 26.


Exercise in inflammatory myopathies, including inclusion body myositis.

Alexanderson H.

Curr Rheumatol Rep. 2012 Jun;14(3):244-51. doi: 10.1007/s11926-012-0248-4. Review.


Effects of immunosuppressive treatment on interleukin-15 and interleukin-15 receptor α expression in muscle tissue of patients with polymyositis or dermatomyositis.

Zong M, Loell I, Lindroos E, Nader GA, Alexanderson H, Hallengren CS, Borg K, Arnardottir S, McInnes IB, Lundberg IE.

Ann Rheum Dis. 2012 Jun;71(6):1055-63. doi: 10.1136/annrheumdis-2011-200495. Epub 2012 Jan 20.


Exercise as a therapeutic modality in patients with idiopathic inflammatory myopathies.

Alexanderson H, Lundberg IE.

Curr Opin Rheumatol. 2012 Mar;24(2):201-7. doi: 10.1097/BOR.0b013e32834f19f5. Review.


Patient preference assessment reveals disease aspects not covered by recommended outcomes in polymyositis and dermatomyositis.

Alemo Munters L, van Vollenhoven RF, Alexanderson H.

ISRN Rheumatol. 2011;2011:463124. doi: 10.5402/2011/463124. Epub 2011 Apr 12.


Patients with polymyositis or dermatomyositis have reduced grip force and health-related quality of life in comparison with reference values: an observational study.

Regardt M, Welin Henriksson E, Alexanderson H, Lundberg IE.

Rheumatology (Oxford). 2011 Mar;50(3):578-85. doi: 10.1093/rheumatology/keq356. Epub 2010 Nov 21.


Higher proportion of fast-twitch (type II) muscle fibres in idiopathic inflammatory myopathies - evident in chronic but not in untreated newly diagnosed patients.

Loell I, Helmers SB, Dastmalchi M, Alexanderson H, Munters LA, Nennesmo I, Lindroos E, Borg K, Lundberg IE, Esbjörnsson M.

Clin Physiol Funct Imaging. 2011 Jan;31(1):18-25. doi: 10.1111/j.1475-097X.2010.00973.x. Epub 2010 Oct 1.


A longitudinal, integrated, clinical, histological and mRNA profiling study of resistance exercise in myositis.

Nader GA, Dastmalchi M, Alexanderson H, Grundtman C, Gernapudi R, Esbjörnsson M, Wang Z, Rönnelid J, Hoffman EP, Nagaraju K, Lundberg IE.

Mol Med. 2010 Nov-Dec;16(11-12):455-64. doi: 10.2119/molmed.2010.00016. Epub 2010 Aug 16.

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