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Concise Review: Intraoperative Strategies for Minimal Manipulation of Autologous Adipose Tissue for Cell- and Tissue-Based Therapies.

Trivisonno A, Alexander RW, Baldari S, Cohen SR, Di Rocco G, Gentile P, Magalon G, Magalon J, Miller RB, Womack H, Toietta G.

Stem Cells Transl Med. 2019 Oct 10. doi: 10.1002/sctm.19-0166. [Epub ahead of print] Review.


Bacterial wobble modifications of NNA-decoding tRNAs.

Nilsson EM, Alexander RW.

IUBMB Life. 2019 Aug;71(8):1158-1166. doi: 10.1002/iub.2120. Epub 2019 Jul 8. Review.


Structure and Dynamics of tRNAMet Containing Core Substitutions.

Godwin RC, Macnamara LM, Alexander RW, Salsbury FR Jr.

ACS Omega. 2018 Sep 30;3(9):10668-10678. doi: 10.1021/acsomega.8b00280. Epub 2018 Sep 5.


Biocellular Regenerative Medicine: Use of Adipose-Derived Stem/Stromal Cells and It's Native Bioactive Matrix.

Alexander RW.

Phys Med Rehabil Clin N Am. 2016 Nov;27(4):871-891. doi: 10.1016/j.pmr.2016.06.005. Review.


Effects of a Health-Partner Intervention on Cardiovascular Risk.

Al Mheid I, Kelli HM, Ko YA, Hammadah M, Ahmed H, Hayek S, Vaccarino V, Ziegler TR, Gibson G, Lampl M, Alexander RW, Brigham K, Martin GS, Quyyumi AA.

J Am Heart Assoc. 2016 Oct 11;5(10). pii: e004217.


IRB reliance: An informatics approach.

Obeid JS, Alexander RW, Gentilin SM, White B, Turley CB, Brady KT, Lenert LA.

J Biomed Inform. 2016 Apr;60:58-65. doi: 10.1016/j.jbi.2016.01.011. Epub 2016 Jan 28.


PGC-1α Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic Diseases.

Xiong S, Patrushev N, Forouzandeh F, Hilenski L, Alexander RW.

Cell Rep. 2015 Sep 1;12(9):1391-9. doi: 10.1016/j.celrep.2015.07.047. Epub 2015 Aug 20.


MD Simulations of tRNA and Aminoacyl-tRNA Synthetases: Dynamics, Folding, Binding, and Allostery.

Li R, Macnamara LM, Leuchter JD, Alexander RW, Cho SS.

Int J Mol Sci. 2015 Jul 13;16(7):15872-902. doi: 10.3390/ijms160715872. Review.


Metformin beyond diabetes: pleiotropic benefits of metformin in attenuation of atherosclerosis.

Forouzandeh F, Salazar G, Patrushev N, Xiong S, Hilenski L, Fei B, Alexander RW.

J Am Heart Assoc. 2014 Dec;3(6):e001202. doi: 10.1161/JAHA.114.001202.


Evidence for late resolution of the aux codon box in evolution.

Jones TE, Ribas de Pouplana L, Alexander RW.

J Biol Chem. 2013 Jul 5;288(27):19625-32. doi: 10.1074/jbc.M112.449249. Epub 2013 May 21.


Autologous fat grafting: use of closed syringe microcannula system for enhanced autologous structural grafting.

Alexander RW, Harrell DB.

Clin Cosmet Investig Dermatol. 2013 Apr 8;6:91-102. doi: 10.2147/CCID.S40575. Print 2013.


Peroxisome proliferator-activated receptor γ coactivator-1α is a central negative regulator of vascular senescence.

Xiong S, Salazar G, Patrushev N, Ma M, Forouzandeh F, Hilenski L, Alexander RW.

Arterioscler Thromb Vasc Biol. 2013 May;33(5):988-98. doi: 10.1161/ATVBAHA.112.301019. Epub 2013 Feb 21. Erratum in: Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):e120.


Proangiogenic cell colonies grown in vitro from human peripheral blood mononuclear cells.

Mavromatis K, Sutcliffe DJ, Joseph G, Alexander RW, Waller EK, Quyyumi AA, Taylor WR.

J Biomol Screen. 2012 Oct;17(9):1128-35. Epub 2012 Aug 17.


Circulating proangiogenic cell activity is associated with cardiovascular disease risk.

Mavromatis K, Aznaouridis K, Al Mheid I, Veledar E, Dhawan S, Murrow JR, Forghani Z, Sutcliffe DJ, Ghasemzadeh N, Alexander RW, Taylor WR, Quyyumi AA.

J Biomol Screen. 2012 Oct;17(9):1163-70. Epub 2012 Aug 10.


A genetic risk variant for myocardial infarction on chromosome 6p24 is associated with impaired central hemodynamic indexes.

Patel RS, Morris AA, Ahmed Y, Kavtaradze N, Sher S, Su S, Zafari AM, Din-Dzietham R, Waddy SP, Vaccarino V, Alexander RW, Gibbons G, Quyyumi AA.

Am J Hypertens. 2012 Jul;25(7):797-803. doi: 10.1038/ajh.2012.41. Epub 2012 Apr 19.


Vitamin D status is associated with arterial stiffness and vascular dysfunction in healthy humans.

Al Mheid I, Patel R, Murrow J, Morris A, Rahman A, Fike L, Kavtaradze N, Uphoff I, Hooper C, Tangpricha V, Alexander RW, Brigham K, Quyyumi AA.

J Am Coll Cardiol. 2011 Jul 5;58(2):186-92. doi: 10.1016/j.jacc.2011.02.051.


Oxidative stress is associated with impaired arterial elasticity.

Patel RS, Al Mheid I, Morris AA, Ahmed Y, Kavtaradze N, Ali S, Dabhadkar K, Brigham K, Hooper WC, Alexander RW, Jones DP, Quyyumi AA.

Atherosclerosis. 2011 Sep;218(1):90-5. doi: 10.1016/j.atherosclerosis.2011.04.033. Epub 2011 May 6.


Mitochondrial aminoacyl-tRNA synthetase single-nucleotide polymorphisms that lead to defects in refolding but not aminoacylation.

Banerjee R, Reynolds NM, Yadavalli SS, Rice C, Roy H, Banerjee P, Alexander RW, Ibba M.

J Mol Biol. 2011 Jul 8;410(2):280-93. doi: 10.1016/j.jmb.2011.05.011. Epub 2011 May 13.


Autologous fat grafting as a mesenchymal stem cell source and living bioscaffold in a patellar tendon tear.

Albano JJ, Alexander RW.

Clin J Sport Med. 2011 Jul;21(4):359-61. doi: 10.1097/JSM.0b013e31821d0864. No abstract available.


Misacylation of specific nonmethionyl tRNAs by a bacterial methionyl-tRNA synthetase.

Jones TE, Alexander RW, Pan T.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6933-8. doi: 10.1073/pnas.1019033108. Epub 2011 Apr 11.


Role for a conserved structural motif in assembly of a class I aminoacyl-tRNA synthetase active site.

Casina VC, Lobashevsky AA, McKinney WE, Brown CL, Alexander RW.

Biochemistry. 2011 Feb 8;50(5):763-9. doi: 10.1021/bi101375d. Epub 2011 Jan 11.


FoxO1 mediates an autofeedback loop regulating SIRT1 expression.

Xiong S, Salazar G, Patrushev N, Alexander RW.

J Biol Chem. 2011 Feb 18;286(7):5289-99. doi: 10.1074/jbc.M110.163667. Epub 2010 Dec 13.


Early endosomal antigen 1 (EEA1) is an obligate scaffold for angiotensin II-induced, PKC-alpha-dependent Akt activation in endosomes.

Nazarewicz RR, Salazar G, Patrushev N, San Martin A, Hilenski L, Xiong S, Alexander RW.

J Biol Chem. 2011 Jan 28;286(4):2886-95. doi: 10.1074/jbc.M110.141499. Epub 2010 Nov 20.


President's address. Common mechanisms of multiple diseases: why vegetables and exercise are good for you.

Alexander RW.

Trans Am Clin Climatol Assoc. 2010;121:1-20. No abstract available.


PGC-1 alpha serine 570 phosphorylation and GCN5-mediated acetylation by angiotensin II drive catalase down-regulation and vascular hypertrophy.

Xiong S, Salazar G, San Martin A, Ahmad M, Patrushev N, Hilenski L, Nazarewicz RR, Ma M, Ushio-Fukai M, Alexander RW.

J Biol Chem. 2010 Jan 22;285(4):2474-87. doi: 10.1074/jbc.M109.065235. Epub 2009 Nov 23.


Experimental and computational determination of tRNA dynamics.

Alexander RW, Eargle J, Luthey-Schulten Z.

FEBS Lett. 2010 Jan 21;584(2):376-86. doi: 10.1016/j.febslet.2009.11.061. Review.


Part-time careers in academic internal medicine: a report from the association of specialty professors part-time careers task force on behalf of the alliance for academic internal medicine.

Linzer M, Warde C, Alexander RW, Demarco DM, Haupt A, Hicks L, Kutner J, Mangione CM, Mechaber H, Rentz M, Riley J, Schuster B, Solomon GD, Volberding P, Ibrahim T; Association of Specialty Professors Part-Time Careers Task Force.

Acad Med. 2009 Oct;84(10):1395-400. doi: 10.1097/ACM.0b013e3181b6bf8c.


Bone marrow mobilization with granulocyte macrophage colony-stimulating factor improves endothelial dysfunction and exercise capacity in patients with peripheral arterial disease.

Subramaniyam V, Waller EK, Murrow JR, Manatunga A, Lonial S, Kasirajan K, Sutcliffe D, Harris W, Taylor WR, Alexander RW, Quyyumi AA.

Am Heart J. 2009 Jul;158(1):53-60.e1. doi: 10.1016/j.ahj.2009.04.014.


Individual variation in macronutrient regulation measured by proton magnetic resonance spectroscopy of human plasma.

Park Y, Kim SB, Wang B, Blanco RA, Le NA, Wu S, Accardi CJ, Alexander RW, Ziegler TR, Jones DP.

Am J Physiol Regul Integr Comp Physiol. 2009 Jul;297(1):R202-9. doi: 10.1152/ajpregu.90757.2008. Epub 2009 May 20.


Endothelial function and aminothiol biomarkers of oxidative stress in healthy adults.

Ashfaq S, Abramson JL, Jones DP, Rhodes SD, Weintraub WS, Hooper WC, Vaccarino V, Alexander RW, Harrison DG, Quyyumi AA.

Hypertension. 2008 Jul;52(1):80-5. doi: 10.1161/HYPERTENSIONAHA.107.097386. Epub 2008 May 26.


An operational RNA code for faithful assignment of AUG triplets to methionine.

Jones TE, Brown CL, Geslain R, Alexander RW, Ribas de Pouplana L.

Mol Cell. 2008 Feb 15;29(3):401-7. doi: 10.1016/j.molcel.2007.12.021.


Using molecular dynamics to map interaction networks in an aminoacyl-tRNA synthetase.

Budiman ME, Knaggs MH, Fetrow JS, Alexander RW.

Proteins. 2007 Aug 15;68(3):670-89.


Mutational analysis of the Escherichia coli DEAD box protein CsdA.

Turner AM, Love CF, Alexander RW, Jones PG.

J Bacteriol. 2007 Apr;189(7):2769-76. Epub 2007 Jan 26.


Caveolin-dependent angiotensin II type 1 receptor signaling in vascular smooth muscle.

Ushio-Fukai M, Alexander RW.

Hypertension. 2006 Nov;48(5):797-803. Epub 2006 Oct 2. Review. No abstract available.


Impact of time to therapy and reperfusion modality on the efficacy of adenosine in acute myocardial infarction: the AMISTAD-2 trial.

Kloner RA, Forman MB, Gibbons RJ, Ross AM, Alexander RW, Stone GW.

Eur Heart J. 2006 Oct;27(20):2400-5. Epub 2006 Jun 16.


Leukocyte and endothelial angiotensin II type 1 receptors and microvascular thrombotic and inflammatory responses to hypercholesterolemia.

Alexander RW.

Arterioscler Thromb Vasc Biol. 2006 Feb;26(2):240-1. No abstract available.


cAbl tyrosine kinase mediates reactive oxygen species- and caveolin-dependent AT1 receptor signaling in vascular smooth muscle: role in vascular hypertrophy.

Ushio-Fukai M, Zuo L, Ikeda S, Tojo T, Patrushev NA, Alexander RW.

Circ Res. 2005 Oct 14;97(8):829-36. Epub 2005 Sep 8. Retraction in: Circ Res. 2010 Jun 11;106(11):1784.


Caveolin-1 is essential for activation of Rac1 and NAD(P)H oxidase after angiotensin II type 1 receptor stimulation in vascular smooth muscle cells: role in redox signaling and vascular hypertrophy.

Zuo L, Ushio-Fukai M, Ikeda S, Hilenski L, Patrushev N, Alexander RW.

Arterioscler Thromb Vasc Biol. 2005 Sep;25(9):1824-30. Epub 2005 Jun 23. Retraction in: Arterioscler Thromb Vasc Biol. 2011 May;31(5):e9.


A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II).

Ross AM, Gibbons RJ, Stone GW, Kloner RA, Alexander RW; AMISTAD-II Investigators.

J Am Coll Cardiol. 2005 Jun 7;45(11):1775-80.


Role of gp91phox (Nox2)-containing NAD(P)H oxidase in angiogenesis in response to hindlimb ischemia.

Tojo T, Ushio-Fukai M, Yamaoka-Tojo M, Ikeda S, Patrushev N, Alexander RW.

Circulation. 2005 May 10;111(18):2347-55. Epub 2005 May 2.


Mechanisms of reactive oxygen species-dependent downregulation of insulin receptor substrate-1 by angiotensin II.

Taniyama Y, Hitomi H, Shah A, Alexander RW, Griendling KK.

Arterioscler Thromb Vasc Biol. 2005 Jun;25(6):1142-7. Epub 2005 Mar 31.


Novel role of ARF6 in vascular endothelial growth factor-induced signaling and angiogenesis.

Ikeda S, Ushio-Fukai M, Zuo L, Tojo T, Dikalov S, Patrushev NA, Alexander RW.

Circ Res. 2005 Mar 4;96(4):467-75. Epub 2005 Feb 3.


Tumor necrosis factor alpha stimulation of Rac1 activity. Role of isoprenylcysteine carboxylmethyltransferase.

Papaharalambus C, Sajjad W, Syed A, Zhang C, Bergo MO, Alexander RW, Ahmad M.

J Biol Chem. 2005 May 13;280(19):18790-6. Epub 2005 Jan 12.


CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: report from the laboratory science discussion group.

Myers GL, Rifai N, Tracy RP, Roberts WL, Alexander RW, Biasucci LM, Catravas JD, Cole TG, Cooper GR, Khan BV, Kimberly MM, Stein EA, Taubert KA, Warnick GR, Waymack PP; CDC; AHA.

Circulation. 2004 Dec 21;110(25):e545-9. No abstract available.


Reactive oxygen species as mediators of angiogenesis signaling: role of NAD(P)H oxidase.

Ushio-Fukai M, Alexander RW.

Mol Cell Biochem. 2004 Sep;264(1-2):85-97. Review.


IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation.

Yamaoka-Tojo M, Ushio-Fukai M, Hilenski L, Dikalov SI, Chen YE, Tojo T, Fukai T, Fujimoto M, Patrushev NA, Wang N, Kontos CD, Bloom GS, Alexander RW.

Circ Res. 2004 Aug 6;95(3):276-83. Epub 2004 Jun 24.


Getting stents to go with the flow.

Alexander RW.

J Clin Invest. 2004 Jun;113(11):1532-4.


Peptide synthesis through evolution.

Tamura K, Alexander RW.

Cell Mol Life Sci. 2004 Jun;61(11):1317-30. Review.


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