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Extracorporeal Membrane Oxygenation Support After Heart Transplantation in Children-Outcomes of a Single Center Cohort.

Nair AG, Sleeper LA, Smoot LB, Wigmore D, Mecklosky J, Andren K, Bastardi HJ, Blume ED, Fynn-Thompson F, Thiagarajan RR, Alexander PMA.

Pediatr Crit Care Med. 2019 Oct 28. doi: 10.1097/PCC.0000000000002192. [Epub ahead of print]


Point-of-Care Procedure for Enhancement of Meniscal Healing in a Goat Model Utilizing Infrapatellar Fat Pad-Derived Stromal Vascular Fraction Cells Seeded in Photocrosslinkable Hydrogel.

Rothrauff BB, Sasaki H, Kihara S, Overholt KJ, Gottardi R, Lin H, Fu FH, Tuan RS, Alexander PG.

Am J Sports Med. 2019 Oct 23:363546519880468. doi: 10.1177/0363546519880468. [Epub ahead of print]


The Relationship Between Tumor Budding, Tumor Microenvironment, and Survival in Patients with Primary Operable Colorectal Cancer.

van Wyk HC, Roseweir A, Alexander P, Park JH, Horgan PG, McMillan DC, Edwards J.

Ann Surg Oncol. 2019 Oct 11. doi: 10.1245/s10434-019-07931-6. [Epub ahead of print]


Mortality and Factors Associated With Hemorrhage During Pediatric Extracorporeal Membrane Oxygenation.

O'Halloran CP, Andren KG, Mecklosky J, Larsen S, Brediger S, Vitali S, Zalieckas JM, Fynn-Thompson F, Thiagarajan RR, Alexander PMA.

Pediatr Crit Care Med. 2019 Jun 27. doi: 10.1097/PCC.0000000000002073. [Epub ahead of print]


Another Outcome Lost to the Benefits of Levosimendan?

Alexander PMA, Akcan-Arikan A, Shekerdemian LS.

Pediatr Crit Care Med. 2019 Oct;20(10):992-994. doi: 10.1097/PCC.0000000000002019. No abstract available.


Outcomes of Infants Supported With Extracorporeal Membrane Oxygenation Using Centrifugal Versus Roller Pumps: An Analysis From the Extracorporeal Life Support Organization Registry.

O'Halloran CP, Thiagarajan RR, Yarlagadda VV, Barbaro RP, Nasr VG, Rycus P, Anders M, Alexander PMA.

Pediatr Crit Care Med. 2019 Sep 27. doi: 10.1097/PCC.0000000000002103. [Epub ahead of print]


Pediatric Hemoptysis without Bronchiectasis or Cardiac Disease: Etiology, Recurrence, and Mortality.

Chiel L, Welsh S, Andren K, Mecklosky J, Alexander PMA, Casey A, Fishman MP.

J Pediatr. 2019 Nov;214:66-70. doi: 10.1016/j.jpeds.2019.07.049. Epub 2019 Sep 17.


Structured review of post-cardiotomy extracorporeal membrane oxygenation: part 1-Adult patients.

Lorusso R, Raffa GM, Alenizy K, Sluijpers N, Makhoul M, Brodie D, McMullan M, Wang IW, Meani P, MacLaren G, Kowalewski M, Dalton H, Barbaro R, Hou X, Cavarocchi N, Chen YS, Thiagarajan R, Alexander P, Alsoufi B, Bermudez CA, Shah AS, Haft J, D'Alessandro DA, Boeken U, Whitman GJR.

J Heart Lung Transplant. 2019 Nov;38(11):1125-1143. doi: 10.1016/j.healun.2019.08.014. Epub 2019 Aug 10.


Muscle injury promotes heterotopic ossification by stimulating local bone morphogenetic protein-7 production.

Li, Jiang Y, Lin H, Shen H, Sohn J, Alexander PG, Tuan RS.

J Orthop Translat. 2019 Jul 5;18:142-153. doi: 10.1016/ eCollection 2019 Jul.


Structured review of post-cardiotomy extracorporeal membrane oxygenation: Part 2-pediatric patients.

Lorusso R, Raffa GM, Kowalewski M, Alenizy K, Sluijpers N, Makhoul M, Brodie D, McMullan M, Wang IW, Meani P, MacLaren G, Dalton H, Barbaro R, Hou X, Cavarocchi N, Chen YS, Thiagarajan R, Alexander P, Alsoufi B, Bermudez CA, Shah AS, Haft J, Oreto L, D'Alessandro DA, Boeken U, Whitman G.

J Heart Lung Transplant. 2019 Nov;38(11):1144-1161. doi: 10.1016/j.healun.2019.07.004. Epub 2019 Jul 17.


Second harmonic generation detection of Ras conformational changes and discovery of a small molecule binder.

Donohue E, Khorsand S, Mercado G, Varney KM, Wilder PT, Yu W, MacKerell AD Jr, Alexander P, Van QN, Moree B, Stephen AG, Weber DJ, Salafsky J, McCormick F.

Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17290-17297. doi: 10.1073/pnas.1905516116. Epub 2019 Aug 9.


Structures of N-terminally processed KRAS provide insight into the role of N-acetylation.

Dharmaiah S, Tran TH, Messing S, Agamasu C, Gillette WK, Yan W, Waybright T, Alexander P, Esposito D, Nissley DV, McCormick F, Stephen AG, Simanshu DK.

Sci Rep. 2019 Jul 19;9(1):10512. doi: 10.1038/s41598-019-46846-w.


The efficacy and safety of tranexamic acid for reducing blood loss following simultaneous bilateral total knee arthroplasty: a multicenter retrospective study.

Cao G, Chen G, Huang Q, Huang Z, Alexander PG, Lin H, Xu H, Zhou Z, Pei F.

BMC Musculoskelet Disord. 2019 Jul 12;20(1):325. doi: 10.1186/s12891-019-2692-z.


Epidemiology of childhood death in Australian and New Zealand intensive care units.

Moynihan KM, Alexander PMA, Schlapbach LJ, Millar J, Jacobe S, Ravindranathan H, Croston EJ, Staffa SJ, Burns JP, Gelbart B; Australian and New Zealand Intensive Care Society Pediatric Study Group (ANZICS PSG) and the ANZICS Centre for Outcome and Resource Evaluation (ANZICS CORE).

Intensive Care Med. 2019 Sep;45(9):1262-1271. doi: 10.1007/s00134-019-05675-1. Epub 2019 Jul 3.


A comparison of regional brain volumes and white matter connectivity in subjects with stimulant induced psychosis versus schizophrenia.

Alexander PD, Gicas KM, Cheng A, Lang DJ, Procyshyn RM, Vertinsky AT, Panenka WJ, Thornton AE, Rauscher A, Wong JYX, Chan T, Jones AA, Vila-Rodriguez F, Honer WG, Barr AM.

Psychopharmacology (Berl). 2019 Jun 22. doi: 10.1007/s00213-019-05298-w. [Epub ahead of print]


Spontaneous resolution of serous macular detachment and outer retinal defect in optic disc pit maculopathy.

Grassi P, Alexander P.

Clin Exp Optom. 2019 Jun 2. doi: 10.1111/cxo.12926. [Epub ahead of print] No abstract available.


The Augmentation of Retinogeniculate Communication during Thalamic Burst Mode.

Alitto H, Rathbun DL, Vandeleest JJ, Alexander PC, Usrey WM.

J Neurosci. 2019 Jul 17;39(29):5697-5710. doi: 10.1523/JNEUROSCI.2320-18.2019. Epub 2019 May 20.


Homozygous Type IX collagen variants (COL9A1, COL9A2, and COL9A3) causing recessive Stickler syndrome-Expanding the phenotype.

Nixon TRW, Alexander P, Richards A, McNinch A, Bearcroft PWP, Cobben J, Snead MP.

Am J Med Genet A. 2019 Aug;179(8):1498-1506. doi: 10.1002/ajmg.a.61191. Epub 2019 May 14.


Optimization of photocrosslinked gelatin/hyaluronic acid hybrid scaffold for the repair of cartilage defect.

Lin H, Beck AM, Shimomura K, Sohn J, Fritch MR, Deng Y, Kilroy EJ, Tang Y, Alexander PG, Tuan RS.

J Tissue Eng Regen Med. 2019 Aug;13(8):1418-1429. doi: 10.1002/term.2883. Epub 2019 Jun 19.


Why the US-China trade war spells disaster for the Amazon.

Fuchs R, Alexander P, Brown C, Cossar F, Henry RC, Rounsevell M.

Nature. 2019 Mar;567(7749):451-454. doi: 10.1038/d41586-019-00896-2. No abstract available.


Conduits harnessing spatially controlled cell-secreted neurotrophic factors improve peripheral nerve regeneration.

Sun AX, Prest TA, Fowler JR, Brick RM, Gloss KM, Li X, DeHart M, Shen H, Yang G, Brown BN, Alexander PG, Tuan RS.

Biomaterials. 2019 May;203:86-95. doi: 10.1016/j.biomaterials.2019.01.038. Epub 2019 Feb 19.


The Extracorporeal Life Support Organization Registry: update and perspectives.

Lorusso R, Alexander P, Rycus P, Barbaro R.

Ann Cardiothorac Surg. 2019 Jan;8(1):93-98. doi: 10.21037/acs.2018.11.03.


Patient Values and Preferences Regarding Continuous Subcutaneous Insulin Infusion and Artificial Pancreas in Adults with Type 1 Diabetes: A Systematic Review of Quantitative and Qualitative Data.

Muñoz-Velandia O, Guyatt G, Devji T, Zhang Y, Li SA, Alexander PE, Henao D, Gomez AM, Ruiz-Morales Á.

Diabetes Technol Ther. 2019 Apr;21(4):183-200. doi: 10.1089/dia.2018.0346. Epub 2019 Mar 6.


Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa.

Uyeki TM, Bernstein HH, Bradley JS, Englund JA, File TM, Fry AM, Gravenstein S, Hayden FG, Harper SA, Hirshon JM, Ison MG, Johnston BL, Knight SL, McGeer A, Riley LE, Wolfe CR, Alexander PE, Pavia AT.

Clin Infect Dis. 2019 Mar 5;68(6):895-902. doi: 10.1093/cid/ciy874. No abstract available.


Re: Baumgarten et al.: Vitrectomy with and without encircling band for pseudophakic retinal detachment with inferior breaks: VIPER Study Report No. 3. Graefes Arch Clin Exp Ophthalmol. 2018 Nov;256(11):2069-2073. doi: 10.1007/s00417-018-4106-6. Epub 2018 Aug 23.

Grassi P, Alexander P, Poulson AV, Snead MP.

Graefes Arch Clin Exp Ophthalmol. 2019 Apr;257(4):843. doi: 10.1007/s00417-019-04268-4. Epub 2019 Feb 20. No abstract available.


Structured decision-making drives guidelines panels' recommendations "for" but not "against" health interventions.

Djulbegovic B, Reljic T, Elqayam S, Cuker A, Hozo I, Zhou Q, Li SA, Alexander P, Nieuwlaat R, Wiercioch W, Schünemann H, Guyatt G.

J Clin Epidemiol. 2019 Jun;110:23-33. doi: 10.1016/j.jclinepi.2019.02.009. Epub 2019 Feb 16.


Individual differences in college-age learners: The importance of relational reasoning for learning and assessment in higher education.

Alexander PA.

Br J Educ Psychol. 2019 Sep;89(3):416-428. doi: 10.1111/bjep.12264. Epub 2019 Jan 11.


Bone morphogenetic protein 4 (BMP4) loss-of-function variant associated with autosomal dominant Stickler syndrome and renal dysplasia.

Nixon TRW, Richards A, Towns LK, Fuller G, Abbs S, Alexander P, McNinch A, Sandford RN, Snead MP.

Eur J Hum Genet. 2019 Mar;27(3):369-377. doi: 10.1038/s41431-018-0316-y. Epub 2018 Dec 19.


Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa.

Uyeki TM, Bernstein HH, Bradley JS, Englund JA, File TM, Fry AM, Gravenstein S, Hayden FG, Harper SA, Hirshon JM, Ison MG, Johnston BL, Knight SL, McGeer A, Riley LE, Wolfe CR, Alexander PE, Pavia AT.

Clin Infect Dis. 2019 Mar 5;68(6):e1-e47. doi: 10.1093/cid/ciy866.


Local mutational diversity drives intratumoral immune heterogeneity in non-small cell lung cancer.

Jia Q, Wu W, Wang Y, Alexander PB, Sun C, Gong Z, Cheng JN, Sun H, Guan Y, Xia X, Yang L, Yi X, Wan YY, Wang H, He J, Futreal PA, Li QJ, Zhu B.

Nat Commun. 2018 Dec 18;9(1):5361. doi: 10.1038/s41467-018-07767-w.


Enhancing chondrogenesis and mechanical strength retention in physiologically relevant hydrogels with incorporation of hyaluronic acid and direct loading of TGF-β.

Deng Y, Sun AX, Overholt KJ, Yu GZ, Fritch MR, Alexander PG, Shen H, Tuan RS, Lin H.

Acta Biomater. 2019 Jan 1;83:167-176. doi: 10.1016/j.actbio.2018.11.022. Epub 2018 Nov 17.


Diagnostic accuracy of imaging brain vesicular monoamine transporter type 2 (VMAT2) in clinically uncertain parkinsonian syndrome (CUPS): a 3-year follow-up study in community patients.

Xu SS, Alexander PK, Lie Y, Dore V, Bozinovski S, Mulligan RS, Young K, Villemagne VL, Rowe CC.

BMJ Open. 2018 Nov 15;8(11):e025533. doi: 10.1136/bmjopen-2018-025533.


Why "Culture" matters for planetary health.

Wilson M, Gathorne-Hardy A, Alexander P, Boden L.

Lancet Planet Health. 2018 Nov;2(11):e467-e468. doi: 10.1016/S2542-5196(18)30205-5. No abstract available.


Damage control surgery for perforated diverticulitis: a two center experience with two different abdominal negative pressure therapy devices.

Gasser E, Alexander P, Reich-Weinberger S, Buchner S, Kogler P, Zitt M, Kafka-Ritsch R, Öfner D.

Acta Chir Belg. 2019 Dec;119(6):370-375. doi: 10.1080/00015458.2018.1534397. Epub 2018 Nov 2.


Prevalence of optic disc haemorrhages in an elderly UK Caucasian population and possible association with reticular pseudodrusen-the Bridlington Eye Assessment Project (BEAP): a cross-sectional study (2002-2006).

Wilde C, Poostchi A, Narendran R, MacNab HK, Hillman JG, Alexander P, Amoaku WM, Vernon SA.

Eye (Lond). 2019 Apr;33(4):580-586. doi: 10.1038/s41433-018-0263-4. Epub 2018 Nov 1.


Macular Detachment for the Treatment of Persistent Full-Thickness Macular Holes.

Fotis K, Alexander P, Sax J, Reddie I, Kang CY, Chandra A.

Retina. 2019 Oct;39 Suppl 1:S104-S107. doi: 10.1097/IAE.0000000000002370. No abstract available.


Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers.

Ding Y, Gong C, Huang, Chen R, Sui P, Lin KH, Liang G, Yuan L, Xiang H, Chen J, Yin T, Alexander PB, Wang QF, Song EW, Li QJ, Wood KC, Wang XF.

Nat Commun. 2018 Oct 15;9(1):4274. doi: 10.1038/s41467-018-06651-x.


Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells.

Zhao L, He R, Long H, Guo B, Jia Q, Qin D, Liu SQ, Wang Z, Xiang T, Zhang J, Tan Y, Huang J, Chen J, Wang F, Xiao M, Gao J, Yang X, Zeng H, Wang X, Hu C, Alexander PB, Symonds ALJ, Yu J, Wan Y, Li QJ, Ye L, Zhu B.

Nat Med. 2018 Oct;24(10):1536-1544. doi: 10.1038/s41591-018-0205-5. Epub 2018 Oct 8.


Evidence to Decision framework provides a structured "roadmap" for making GRADE guidelines recommendations.

Li SA, Alexander PE, Reljic T, Cuker A, Nieuwlaat R, Wiercioch W, Guyatt G, Schünemann HJ, Djulbegovic B.

J Clin Epidemiol. 2018 Dec;104:103-112. doi: 10.1016/j.jclinepi.2018.09.007. Epub 2018 Sep 22.


Eighteen years of paediatric extracorporeal membrane oxygenation and ventricular assist devices: insight regarding late outcomes.

Shah SM, Kays DW, Ghazarian SR, Karl TR, Alexander P, Sznycer-Taub N, Parker J, Oldeen M, Almodovar MC, Stapleton G, Quintessenza JA, Asante-Korang A, Kartha V, Hanson J, Amankwah E, Roth J, Jacobs JP.

Cardiol Young. 2018 Nov;28(11):1316-1322. doi: 10.1017/S1047951118001282. Epub 2018 Sep 17.


Comparison and Feasibility of Various RFID Authentication Methods Using ECC.

Alexander P Jr, Baashirah R, Abuzneid A.

Sensors (Basel). 2018 Sep 1;18(9). pii: E2902. doi: 10.3390/s18092902. Review.


Risk Factors for Survival After Heart Transplantation in Children and Young Adults: A 22-Year Study of 179 Transplants.

Shah S, Asante-Korang A, Ghazarian SR, Stapleton G, Herbert C, Decker J, Almodovar MC, Karl TR, Do NL, Quintessenza JA, Mavroudis C, Vricella LA, van Gelder HM, Kartha V, Alexander P, Carapellucci J, Krasnopero D, Hanson J, Amankwah E, Roth J, Jacobs JP.

World J Pediatr Congenit Heart Surg. 2018 Sep;9(5):557-564. doi: 10.1177/2150135118782190.


Surgical treatment for a case of coronary steal from a traumatic coronary artery-cameral fistula after blunt cardiac injury.

Chow KL, Alexander PJ, Sur JP, Omi EC.

Int J Surg Case Rep. 2018;51:50-53. doi: 10.1016/j.ijscr.2018.08.017. Epub 2018 Aug 13.


Highlights from the Extracorporeal Life Support Organization Registry: 2006-2017.

Nasr VG, Raman L, Barbaro RP, Guner Y, Tonna J, Ramanathan K, Pappalardo F, Thiagarajan RR, Alexander PMA; ELSO Registry Scientific Oversight Committee.

ASAIO J. 2019 Aug;65(6):537-544. doi: 10.1097/MAT.0000000000000863.


Accurate Prediction of Congenital Heart Surgical Length of Stay Incorporating a Procedure-Based Categorical Variable.

Alexander PMA, DiOrio M, Andren K, Gauvreau K, Mistry KP, Mathieu D, Wright J, Allan CK, Nathan M, Mayer JE Jr, Thiagarajan RR, Bergersen L.

Pediatr Crit Care Med. 2018 Oct;19(10):949-956. doi: 10.1097/PCC.0000000000001668.


Effect of Platelet-Rich Plasma on Chondrogenic Differentiation of Adipose- and Bone Marrow-Derived Mesenchymal Stem Cells.

Liou JJ, Rothrauff BB, Alexander PG, Tuan RS.

Tissue Eng Part A. 2018 Oct;24(19-20):1432-1443. doi: 10.1089/ten.tea.2018.0065. Epub 2018 Jul 23.


In Vitro Repair of Meniscal Radial Tear With Hydrogels Seeded With Adipose Stem Cells and TGF-β3.

Sasaki H, Rothrauff BB, Alexander PG, Lin H, Gottardi R, Fu FH, Tuan RS.

Am J Sports Med. 2018 Aug;46(10):2402-2413. doi: 10.1177/0363546518782973. Epub 2018 Jul 12.


Factors Associated With Mortality in Children Who Successfully Wean From Extracorporeal Membrane Oxygenation.

Howard TS, Kalish BT, Rajagopal SK, Williams K, Zalieckas J, Thiagarajan RR, Alexander PMA.

Pediatr Crit Care Med. 2018 Sep;19(9):875-883. doi: 10.1097/PCC.0000000000001642.


RBC Exposure in Pediatric Extracorporeal Membrane Oxygenation: Epidemiology and Factors Associated With Large Blood Transfusion Volume.

O'Halloran CP, Alexander PMA, Andren KG, Mecklosky J, Salvin JW, Larsen S, Zalieckas J, Fynn-Thompson F, Thiagarajan RR.

Pediatr Crit Care Med. 2018 Aug;19(8):767-774. doi: 10.1097/PCC.0000000000001596.


An Ethical Claim for Providing Medical Recommendations in Pediatric Intensive Care.

Moynihan KM, Jansen MA, Liaw SN, Alexander PMA, Truog RD.

Pediatr Crit Care Med. 2018 Aug;19(8):e433-e437. doi: 10.1097/PCC.0000000000001591.


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