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Deep Learning-Based Histopathologic Assessment of Kidney Tissue.

Hermsen M, de Bel T, den Boer M, Steenbergen EJ, Kers J, Florquin S, Roelofs JJTH, Stegall MD, Alexander MP, Smith BH, Smeets B, Hilbrands LB, van der Laak JAWM.

J Am Soc Nephrol. 2019 Sep 5. pii: ASN.2019020144. doi: 10.1681/ASN.2019020144. [Epub ahead of print]


De novo pauci-immune glomerulonephritis in renal allografts.

Buglioni A, Fidler ME, Alexander MP, Sethi S, Nasr SH, Hernandez LPH, Grande JP, Cosio FG, Cornell LD.

Mod Pathol. 2019 Sep 2. doi: 10.1038/s41379-019-0355-0. [Epub ahead of print]


The sensitivity and specificity of the routine kidney biopsy immunofluorescence panel are inferior to diagnosing renal immunoglobulin-derived amyloidosis by mass spectrometry.

Gonzalez Suarez ML, Zhang P, Nasr SH, Sathick IJ, Kittanamongkolchai W, Kurtin PJ, Alexander MP, Cornell LD, Fidler ME, Grande JP, Herrera Hernandez LP, Said SM, Sethi S, Dispenzieri A, Gertz MA, Leung N.

Kidney Int. 2019 Jun 25. pii: S0085-2538(19)30611-8. doi: 10.1016/j.kint.2019.05.027. [Epub ahead of print]


Dysproteinemia and the Kidney: Core Curriculum 2019.

Hogan JJ, Alexander MP, Leung N.

Am J Kidney Dis. 2019 Jul 19. pii: S0272-6386(19)30798-X. doi: 10.1053/j.ajkd.2019.04.029. [Epub ahead of print] Review.


Serum levels of DNAJB9 are elevated in fibrillary glomerulonephritis patients.

Nasr SH, Dasari S, Lieske JC, Benson LM, Vanderboom PM, Holtz-Heppelmann CJ, Giesen CD, Snyder MR, Erickson SB, Fervenza FC, Leung N, Kurtin PJ, Alexander MP.

Kidney Int. 2019 May;95(5):1269-1272. doi: 10.1016/j.kint.2019.01.024. Epub 2019 Mar 1.


Heavy Chain Fibrillary Glomerulonephritis: A Case Report.

Nasr SH, Sirac C, Bridoux F, Javaugue V, Bender S, Rinsant A, Kaaki S, Pinault E, Dasari S, Alexander MP, Said SM, Hogan JJ, Dispenzieri A, Touchard G, McPhail ED, Leung N.

Am J Kidney Dis. 2019 Aug;74(2):276-280. doi: 10.1053/j.ajkd.2019.01.032. Epub 2019 Apr 5.


Using computer-assisted morphometrics of 5-year biopsies to identify biomarkers of late renal allograft loss.

Denic A, Morales MC, Park WD, Smith BH, Kremers WK, Alexander MP, Cosio FG, Rule AD, Stegall MD.

Am J Transplant. 2019 Apr 4. doi: 10.1111/ajt.15380. [Epub ahead of print]


Cloning, function, and localization of human, canine, and Drosophila ZIP10 (SLC39A10), a Zn2+ transporter.

Landry GM, Furrow E, Holmes HL, Hirata T, Kato A, Williams P, Strohmaier K, Gallo CJR, Chang M, Pandey MK, Jiang H, Bansal A, Franz MC, Montalbetti N, Alexander MP, Cabrero P, Dow JAT, DeGrado TR, Romero MF.

Am J Physiol Renal Physiol. 2019 Feb 1;316(2):F263-F273. doi: 10.1152/ajprenal.00573.2017. Epub 2018 Dec 6.


Transplantation of HCV-infected organs into uninfected recipients: Advance with caution.

Wadei HM, Pungpapong S, Cortese C, Alexander MP, Keaveny AP, Yang L, Taner CB, Croome KP.

Am J Transplant. 2019 Mar;19(3):960-961. doi: 10.1111/ajt.15152. Epub 2018 Nov 26. No abstract available.


A method to reduce variability in scoring antibody-mediated rejection in renal allografts: implications for clinical trials - a retrospective study.

Smith B, Cornell LD, Smith M, Cortese C, Geiger X, Alexander MP, Ryan M, Park W, Morales Alvarez MC, Schinstock C, Kremers W, Stegall M.

Transpl Int. 2019 Feb;32(2):173-183. doi: 10.1111/tri.13340. Epub 2018 Oct 2.


Beta-glucan-induced inflammatory monocytes mediate antitumor efficacy in the murine lung.

Alexander MP, Fiering SN, Ostroff GR, Cramer RA, Mullins DW.

Cancer Immunol Immunother. 2018 Nov;67(11):1731-1742. doi: 10.1007/s00262-018-2234-9. Epub 2018 Aug 23.


Congophilic Fibrillary Glomerulonephritis: A Case Series.

Alexander MP, Dasari S, Vrana JA, Riopel J, Valeri AM, Markowitz GS, Hever A, Bijol V, Larsen CP, Cornell LD, Fidler ME, Said SM, Sethi S, Herrera Hernandez LP, Grande JP, Erickson SB, Fervenza FC, Leung N, Kurtin PJ, Nasr SH.

Am J Kidney Dis. 2018 Sep;72(3):325-336. doi: 10.1053/j.ajkd.2018.03.017. Epub 2018 Jun 14.


Clinical and Pathology Findings Associate Consistently with Larger Glomerular Volume.

Denic A, Mathew J, Nagineni VV, Thompson RH, Leibovich BC, Lerman LO, Lieske JC, Alexander MP, Augustine JJ, Kremers WK, Rule AD.

J Am Soc Nephrol. 2018 Jul;29(7):1960-1969. doi: 10.1681/ASN.2017121305. Epub 2018 May 22. Erratum in: J Am Soc Nephrol. 2018 Sep;29(9):2445.


Proliferative glomerulonephritis with monoclonal immunoglobulin G deposits is associated with high rate of early recurrence in the allograft.

Said SM, Cosio FG, Valeri AM, Leung N, Sethi S, Salameh H, Cornell LD, Fidler ME, Alexander MP, Fervenza FC, Drosou ME, Zhang D, D'Agati VD, Nasr SH.

Kidney Int. 2018 Jul;94(1):159-169. doi: 10.1016/j.kint.2018.01.028. Epub 2018 Apr 30.


Harnessing innate lung anti-cancer effector functions with a novel bacterial-derived immunotherapy.

Bazett M, Costa AM, Bosiljcic M, Anderson RM, Alexander MP, Wong SWY, Dhanji S, Chen JM, Pankovich J, Lam S, Sutcliffe S, Gunn H, Kalyan S, Mullins DW.

Oncoimmunology. 2017 Nov 27;7(3):e1398875. doi: 10.1080/2162402X.2017.1398875. eCollection 2018.


DNAJB9 Is a Specific Immunohistochemical Marker for Fibrillary Glomerulonephritis.

Nasr SH, Vrana JA, Dasari S, Bridoux F, Fidler ME, Kaaki S, Quellard N, Rinsant A, Goujon JM, Sethi S, Fervenza FC, Cornell LD, Said SM, McPhail ED, Herrera Hernandez LP, Grande JP, Hogan MC, Lieske JC, Leung N, Kurtin PJ, Alexander MP.

Kidney Int Rep. 2017 Aug 8;3(1):56-64. doi: 10.1016/j.ekir.2017.07.017. eCollection 2018 Jan.


Dense deposit disease associated with multiple myeloma

Alkhunaizi AM, AlKhatti AA, Nasr SH, Alexander MP.

Clin Nephrol. 2018 Apr;89(4):300-304. doi: 10.5414/CN109308.


The Incidence of Primary vs Secondary Focal Segmental Glomerulosclerosis: A Clinicopathologic Study.

Hommos MS, De Vriese AS, Alexander MP, Sethi S, Vaughan L, Zand L, Bharucha K, Lepori N, Rule AD, Fervenza FC.

Mayo Clin Proc. 2017 Dec;92(12):1772-1781. doi: 10.1016/j.mayocp.2017.09.011. Epub 2017 Oct 27.


DnaJ Heat Shock Protein Family B Member 9 Is a Novel Biomarker for Fibrillary GN.

Dasari S, Alexander MP, Vrana JA, Theis JD, Mills JR, Negron V, Sethi S, Dispenzieri A, Highsmith WE Jr, Nasr SH, Kurtin PJ.

J Am Soc Nephrol. 2018 Jan;29(1):51-56. doi: 10.1681/ASN.2017030306. Epub 2017 Nov 2.


Single-Nephron Glomerular Filtration Rate in Healthy Adults.

Denic A, Mathew J, Lerman LO, Lieske JC, Larson JJ, Alexander MP, Poggio E, Glassock RJ, Rule AD.

N Engl J Med. 2017 Jun 15;376(24):2349-2357. doi: 10.1056/NEJMoa1614329.


The effect of focal cortical frontal and posterior lesions on recollection and familiarity in recognition memory.

Stamenova V, Gao F, Black SE, Schwartz ML, Kovacevic N, Alexander MP, Levine B.

Cortex. 2017 Jun;91:316-326. doi: 10.1016/j.cortex.2017.04.003. Epub 2017 Apr 15.


Concomitant Disruption of CD4 and CD8 Genes Facilitates the Development of Double Negative αβ TCR+ Peripheral T Cells That Respond Robustly to Staphylococcal Superantigen.

Chowdhary VR, Krogman A, Tilahun AY, Alexander MP, David CS, Rajagopalan G.

J Immunol. 2017 Jun 1;198(11):4413-4424. doi: 10.4049/jimmunol.1601991. Epub 2017 May 3.


Clinical, biopsy, and mass spectrometry findings of renal gelsolin amyloidosis.

Sethi S, Dasari S, Amin MS, Vrana JA, Theis JD, Alexander MP, Kurtin PJ.

Kidney Int. 2017 Apr;91(4):964-971. doi: 10.1016/j.kint.2016.11.017. Epub 2017 Jan 29.


Cryofibrinogen-Associated Glomerulonephritis.

Sethi S, Yachoui R, Murray DL, Radhakrishnan J, Alexander MP.

Am J Kidney Dis. 2017 Feb;69(2):302-308. doi: 10.1053/j.ajkd.2016.08.031. Epub 2016 Nov 17.


HLA-DR polymorphisms influence in vivo responses to staphylococcal toxic shock syndrome toxin-1 in a transgenic mouse model.

Krogman A, Tilahun A, David CS, Chowdhary VR, Alexander MP, Rajagopalan G.

HLA. 2017 Jan;89(1):20-28. doi: 10.1111/tan.12930. Epub 2016 Nov 15.


Negative Staining for COL4A5 Correlates With Worse Prognosis and More Severe Ultrastructural Alterations in Males With Alport Syndrome.

Said SM, Fidler ME, Valeri AM, McCann B, Fiedler W, Cornell LD, Alexander MP, Alkhunaizi AM, Sullivan A, Cramer CH, Hogan MC, Nasr SH.

Kidney Int Rep. 2016 Sep 29;2(1):44-52. doi: 10.1016/j.ekir.2016.09.056. eCollection 2017 Jan.


Current anti-myeloma therapies in renal manifestations of monoclonal light chain-associated Fanconi syndrome: a retrospective series of 49 patients.

Vignon M, Javaugue V, Alexander MP, El-Karoui K, Karras A, Roos-Weil D, Royer B, Asli B, Knebelmann B, Touchard G, Jaccard A, Arnulf B, Bridoux F, Leung N, Fermand JP.

Leukemia. 2017 Jan;31(1):123-129. doi: 10.1038/leu.2016.195. Epub 2016 Jul 20.


The Substantial Loss of Nephrons in Healthy Human Kidneys with Aging.

Denic A, Lieske JC, Chakkera HA, Poggio ED, Alexander MP, Singh P, Kremers WK, Lerman LO, Rule AD.

J Am Soc Nephrol. 2017 Jan;28(1):313-320. doi: 10.1681/ASN.2016020154. Epub 2016 Jul 8.


C4d as a marker for masked immune deposits.

Sethi S, Hernandez LH, Alexander MP, Fervenza FC.

Kidney Int. 2016 Jul;90(1):223-4. doi: 10.1016/j.kint.2016.02.041. No abstract available.


Tubulointerstitial Fibrosis of Living Donor Kidneys Associates with Urinary Monocyte Chemoattractant Protein 1.

Wang X, Lieske JC, Alexander MP, Jayachandran M, Denic A, Mathew J, Lerman LO, Kremers WK, Larson JJ, Rule AD.

Am J Nephrol. 2016;43(6):454-9. doi: 10.1159/000446851. Epub 2016 Jun 10.


Clinical, biopsy, and mass spectrometry characteristics of renal apolipoprotein A-IV amyloidosis.

Dasari S, Amin MS, Kurtin PJ, Vrana JA, Theis JD, Grogg KL, Alexander MP, Nasr SH, Fervenza FC, Leung N, Sethi S.

Kidney Int. 2016 Sep;90(3):658-64. doi: 10.1016/j.kint.2016.04.003. Epub 2016 Jun 2.


Independent, Community-Based Aerobic Exercise Training for People With Moderate-to-Severe Traumatic Brain Injury.

Devine JM, Wong B, Gervino E, Pascual-Leone A, Alexander MP.

Arch Phys Med Rehabil. 2016 Aug;97(8):1392-7. doi: 10.1016/j.apmr.2016.04.015. Epub 2016 May 20.


Temporal IgG Subtype Changes in Recurrent Idiopathic Membranous Nephropathy.

Kattah AG, Alexander MP, Angioi A, De Vriese AS, Sethi S, Cosio FG, Lorenz EC, Cornell LD, Fervenza FC.

Am J Transplant. 2016 Oct;16(10):2964-2972. doi: 10.1111/ajt.13806. Epub 2016 May 5.


The clinicopathologic characteristics and outcome of atypical anti-glomerular basement membrane nephritis.

Nasr SH, Collins AB, Alexander MP, Schraith DF, Herrera Hernandez L, Fidler ME, Sethi S, Leung N, Fervenza FC, Cornell LD.

Kidney Int. 2016 Apr;89(4):897-908. doi: 10.1016/j.kint.2016.02.001.


Detection and Clinical Patterns of Nephron Hypertrophy and Nephrosclerosis Among Apparently Healthy Adults.

Denic A, Alexander MP, Kaushik V, Lerman LO, Lieske JC, Stegall MD, Larson JJ, Kremers WK, Vrtiska TJ, Chakkera HA, Poggio ED, Rule AD.

Am J Kidney Dis. 2016 Jul;68(1):58-67. doi: 10.1053/j.ajkd.2015.12.029. Epub 2016 Feb 6.


Rapidly progressive glomerulonephritis due to coexistent anti-glomerular basement membrane disease and fibrillary glomerulonephritis.

Cheungpasitporn W, Zacharek CC, Fervenza FC, Cornell LD, Sethi S, Herrera Hernandez LP, Nasr SH, Alexander MP.

Clin Kidney J. 2016 Feb;9(1):97-101. doi: 10.1093/ckj/sfv126. Epub 2015 Nov 30.


Mayo Clinic/Renal Pathology Society Consensus Report on Pathologic Classification, Diagnosis, and Reporting of GN.

Sethi S, Haas M, Markowitz GS, D'Agati VD, Rennke HG, Jennette JC, Bajema IM, Alpers CE, Chang A, Cornell LD, Cosio FG, Fogo AB, Glassock RJ, Hariharan S, Kambham N, Lager DJ, Leung N, Mengel M, Nath KA, Roberts IS, Rovin BH, Seshan SV, Smith RJ, Walker PD, Winearls CG, Appel GB, Alexander MP, Cattran DC, Casado CA, Cook HT, De Vriese AS, Radhakrishnan J, Racusen LC, Ronco P, Fervenza FC.

J Am Soc Nephrol. 2016 May;27(5):1278-87. doi: 10.1681/ASN.2015060612. Epub 2015 Nov 13.


Renal extramedullary hematopoiesis: interstitial and glomerular pathology.

Alexander MP, Nasr SH, Kurtin PJ, Casey ET, Hernandez LP, Fidler ME, Sethi S, Cornell LD.

Mod Pathol. 2015 Dec;28(12):1574-83. doi: 10.1038/modpathol.2015.117. Epub 2015 Oct 9.


A Corticosteroid Gene Therapy Combination Strategy to Maximize Intramuscular-Mediated Delivery in Postischemic Myocardium.

Fargnoli AS, Katz MG, Alexander MP, Kendle AP, Bridges CR.

Hum Gene Ther Clin Dev. 2015 Sep;26(3):157-8. doi: 10.1089/humc.2015.061. Epub 2015 Jul 24. No abstract available.


C3 glomerulonephritis and autoimmune disease: more than a fortuitous association?

Alexander MP, Fervenza FC, De Vriese AS, Smith RJH, Nasr SH, Cornell LD, Herrera Hernandez LP, Zhang Y, Sethi S.

J Nephrol. 2016 Apr;29(2):203-209. doi: 10.1007/s40620-015-0218-9. Epub 2015 Jul 18.


Membranoproliferative glomerulonephritis with masked monotypic immunoglobulin deposits.

Larsen CP, Messias NC, Walker PD, Fidler ME, Cornell LD, Hernandez LH, Alexander MP, Sethi S, Nasr SH.

Kidney Int. 2015 Oct;88(4):867-73. doi: 10.1038/ki.2015.195. Epub 2015 Jul 8.


Melanoma Induces, and Adenosine Suppresses, CXCR3-Cognate Chemokine Production and T-cell Infiltration of Lungs Bearing Metastatic-like Disease.

Clancy-Thompson E, Perekslis TJ, Croteau W, Alexander MP, Chabanet TB, Turk MJ, Huang YH, Mullins DW.

Cancer Immunol Res. 2015 Aug;3(8):956-67. doi: 10.1158/2326-6066.CIR-15-0015. Epub 2015 Jun 5.


Distinguishing age-related from disease-related glomerulosclerosis on kidney biopsy: the Aging Kidney Anatomy study.

Kremers WK, Denic A, Lieske JC, Alexander MP, Kaushik V, Elsherbiny HE, Chakkera HA, Poggio ED, Rule AD.

Nephrol Dial Transplant. 2015 Dec;30(12):2034-9. doi: 10.1093/ndt/gfv072. Epub 2015 Apr 16.


Mild traumatic brain injury.

Katz DI, Cohen SI, Alexander MP.

Handb Clin Neurol. 2015;127:131-56. doi: 10.1016/B978-0-444-52892-6.00009-X. Review.


Increasing pulmonary infiltrates in a 72-year-old woman with metastatic breast cancer.

Bois MC, Hu X, Roden AC, Yi ES, Ryu JH, Alexander MP.

Chest. 2014 Dec;146(6):e208-e211. doi: 10.1378/chest.14-0761. No abstract available.


Nephron hypertrophy and glomerulosclerosis and their association with kidney function and risk factors among living kidney donors.

Elsherbiny HE, Alexander MP, Kremers WK, Park WD, Poggio ED, Prieto M, Lieske JC, Rule AD.

Clin J Am Soc Nephrol. 2014 Nov 7;9(11):1892-902. doi: 10.2215/CJN.02560314. Epub 2014 Oct 15.


Automated assessment of renal cortical surface roughness from computerized tomography images and its association with age.

Duan X, Rule AD, Elsherbiny H, Vrtiska TJ, Avula RT, Alexander MP, Lerman LO, McCollough CH.

Acad Radiol. 2014 Nov;21(11):1441-5. doi: 10.1016/j.acra.2014.05.014. Epub 2014 Jul 30.


Recovery, long-term cognitive outcome and quality of life following out-of-hospital cardiac arrest.

Lim C, Verfaellie M, Schnyer D, Lafleche G, Alexander MP.

J Rehabil Med. 2014 Jul;46(7):691-7. doi: 10.2340/16501977-1816.


Multiple murine BRaf(V600E) melanoma cell lines with sensitivity to PLX4032.

Jenkins MH, Steinberg SM, Alexander MP, Fisher JL, Ernstoff MS, Turk MJ, Mullins DW, Brinckerhoff CE.

Pigment Cell Melanoma Res. 2014 May;27(3):495-501. doi: 10.1111/pcmr.12220. Epub 2014 Mar 6. No abstract available.


From the thalamus with love: a rare window into the locus of emotional synesthesia.

Schweizer TA, Li Z, Fischer CE, Alexander MP, Smith SD, Graham SJ, Fornazarri L.

Neurology. 2013 Jul 30;81(5):509-10. doi: 10.1212/WNL.0b013e31829d86cc. Epub 2013 Jun 26. No abstract available.


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