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Items: 1 to 50 of 299

1.

Differences in topological progression profile among neurodegenerative diseases from imaging data.

Garbarino S, Lorenzi M, Oxtoby NP, Vinke EJ, Marinescu RV, Eshaghi A, Ikram MA, Niessen WJ, Ciccarelli O, Barkhof F, Schott JM, Vernooij MW, Alexander DC.

Elife. 2019 Dec 3;8. pii: e49298. doi: 10.7554/eLife.49298. [Epub ahead of print]

2.

SVM recursive feature elimination analyses of structural brain MRI predicts near-term relapses in patients with clinically isolated syndromes suggestive of multiple sclerosis.

Wottschel V, Chard DT, Enzinger C, Filippi M, Frederiksen JL, Gasperini C, Giorgio A, Rocca MA, Rovira A, De Stefano N, Tintoré M, Alexander DC, Barkhof F, Ciccarelli O; MAGNIMS study group and the EuroPOND consortium.

Neuroimage Clin. 2019 Oct 22;24:102011. doi: 10.1016/j.nicl.2019.102011. [Epub ahead of print]

3.

Reduced neurite density in the brain and cervical spinal cord in relapsing-remitting multiple sclerosis: A NODDI study.

Collorone S, Cawley N, Grussu F, Prados F, Tona F, Calvi A, Kanber B, Schneider T, Kipp L, Zhang H, Alexander DC, Thompson AJ, Toosy A, Wheeler-Kingshott CAG, Ciccarelli O.

Mult Scler. 2019 Nov 4:1352458519885107. doi: 10.1177/1352458519885107. [Epub ahead of print]

PMID:
31682198
4.

Disease Progression Modelling in Chronic Obstructive Pulmonary Disease (COPD).

Young AL, Bragman FJS, Rangelov B, Han M, Galbán CJ, Lynch DA, Hawkes DJ, Alexander DC, Hurst JR; COPDGene Investigators.

Am J Respir Crit Care Med. 2019 Oct 28. doi: 10.1164/rccm.201908-1600OC. [Epub ahead of print]

PMID:
31657634
5.

Alcohol metabolism contributes to brain histone acetylation.

Mews P, Egervari G, Nativio R, Sidoli S, Donahue G, Lombroso SI, Alexander DC, Riesche SL, Heller EA, Nestler EJ, Garcia BA, Berger SL.

Nature. 2019 Oct;574(7780):717-721. doi: 10.1038/s41586-019-1700-7. Epub 2019 Oct 23.

PMID:
31645761
6.

In Utero Diffusion MRI: Challenges, Advances, and Applications.

Christiaens D, Slator PJ, Cordero-Grande L, Price AN, Deprez M, Alexander DC, Rutherford M, Hajnal JV, Hutter J.

Top Magn Reson Imaging. 2019 Oct;28(5):255-264. doi: 10.1097/RMR.0000000000000211.

PMID:
31592992
7.

Probing axons using multi-compartmental diffusion in multiple sclerosis.

Bagnato F, Franco G, Li H, Kaden E, Ye F, Fan R, Chen A, Alexander DC, Smith SA, Dortch R, Xu J.

Ann Clin Transl Neurol. 2019 Sep;6(9):1595-1605. doi: 10.1002/acn3.50836. Epub 2019 Aug 13.

8.

Multi-study validation of data-driven disease progression models to characterize evolution of biomarkers in Alzheimer's disease.

Archetti D, Ingala S, Venkatraghavan V, Wottschel V, Young AL, Bellio M, Bron EE, Klein S, Barkhof F, Alexander DC, Oxtoby NP, Frisoni GB, Redolfi A; Alzheimer's Disease Neuroimaging Initiative; for EuroPOND Consortium.

Neuroimage Clin. 2019 Jul 23;24:101954. doi: 10.1016/j.nicl.2019.101954. [Epub ahead of print]

9.

Longitudinal neuroanatomical and cognitive progression of posterior cortical atrophy.

Firth NC, Primativo S, Marinescu RV, Shakespeare TJ, Suarez-Gonzalez A, Lehmann M, Carton A, Ocal D, Pavisic I, Paterson RW, Slattery CF, Foulkes AJM, Ridha BH, Gil-Néciga E, Oxtoby NP, Young AL, Modat M, Cardoso MJ, Ourselin S, Ryan NS, Miller BL, Rabinovici GD, Warrington EK, Rossor MN, Fox NC, Warren JD, Alexander DC, Schott JM, Yong KXX, Crutch SJ.

Brain. 2019 Jul 1;142(7):2082-2095. doi: 10.1093/brain/awz136.

10.

Modeling longitudinal imaging biomarkers with parametric Bayesian multi-task learning.

Aksman LM, Scelsi MA, Marquand AF, Alexander DC, Ourselin S, Altmann A; for ADNI.

Hum Brain Mapp. 2019 Sep;40(13):3982-4000. doi: 10.1002/hbm.24682. Epub 2019 Jun 5.

11.

Applying causal models to explore the mechanism of action of simvastatin in progressive multiple sclerosis.

Eshaghi A, Kievit RA, Prados F, Sudre CH, Nicholas J, Cardoso MJ, Chan D, Nicholas R, Ourselin S, Greenwood J, Thompson AJ, Alexander DC, Barkhof F, Chataway J, Ciccarelli O.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):11020-11027. doi: 10.1073/pnas.1818978116. Epub 2019 May 9.

12.

CPHLN recommendations for the laboratory detection of Shiga toxin-producing Escherichia coli (O157 and non-O157).

Chui L, Christianson S, Alexander DC, Arseneau V, Bekal S, Berenger B, Chen Y, Davidson R, Farrell DJ, German GJ, Gilbert L, Hoang L, Johnson RP, MacKeen A, Maki A, Nadon C, Nickerson E, Peralta A, Arneson SR, Yu Y, Ziebell K.

Can Commun Dis Rep. 2018 Nov 1;44(11):304-307. doi: 10.14745/ccdr.v44i11a06. eCollection 2018 Nov 1.

13.

Fixel-based analysis of the preterm brain: Disentangling bundle-specific white matter microstructural and macrostructural changes in relation to clinical risk factors.

Pecheva D, Tournier JD, Pietsch M, Christiaens D, Batalle D, Alexander DC, Hajnal JV, Edwards AD, Zhang H, Counsell SJ.

Neuroimage Clin. 2019;23:101820. doi: 10.1016/j.nicl.2019.101820. Epub 2019 Apr 10.

14.

Combined diffusion-relaxometry MRI to identify dysfunction in the human placenta.

Slator PJ, Hutter J, Palombo M, Jackson LH, Ho A, Panagiotaki E, Chappell LC, Rutherford MA, Hajnal JV, Alexander DC.

Magn Reson Med. 2019 Jul;82(1):95-106. doi: 10.1002/mrm.27733. Epub 2019 Mar 18.

15.

DIVE: A spatiotemporal progression model of brain pathology in neurodegenerative disorders.

Marinescu RV, Eshaghi A, Lorenzi M, Young AL, Oxtoby NP, Garbarino S, Crutch SJ, Alexander DC; Alzheimer's Disease Neuroimaging Initiative.

Neuroimage. 2019 May 15;192:166-177. doi: 10.1016/j.neuroimage.2019.02.053. Epub 2019 Mar 4.

PMID:
30844504
16.

Abnormal Microstructural Development of the Cerebral Cortex in Neonates With Congenital Heart Disease Is Associated With Impaired Cerebral Oxygen Delivery.

Kelly CJ, Christiaens D, Batalle D, Makropoulos A, Cordero-Grande L, Steinweg JK, O'Muircheartaigh J, Khan H, Lee G, Victor S, Alexander DC, Zhang H, Simpson J, Hajnal JV, Edwards AD, Rutherford MA, Counsell SJ.

J Am Heart Assoc. 2019 Mar 5;8(5):e009893. doi: 10.1161/JAHA.118.009893.

17.

Mycobacterium avium in Community and Household Water, Suburban Philadelphia, Pennsylvania, USA, 2010-2012.

Lande L, Alexander DC, Wallace RJ Jr, Kwait R, Iakhiaeva E, Williams M, Cameron ADS, Olshefsky S, Devon R, Vasireddy R, Peterson DD, Falkinham JO 3rd.

Emerg Infect Dis. 2019 Mar;25(3):473-481. doi: 10.3201/eid2503.180336.

18.

Report of a KPC-producing Pseudomonas aeruginosa isolate in Canada.

Walkty A, Alexander DC, Karlowsky JA, Nichol K, Embil J.

J Antimicrob Chemother. 2019 Jun 1;74(6):1748-1749. doi: 10.1093/jac/dkz064. No abstract available.

PMID:
30783655
19.

VERDICT MRI validation in fresh and fixed prostate specimens using patient-specific moulds for histological and MR alignment.

Bailey C, Bourne RM, Siow B, Johnston EW, Brizmohun Appayya M, Pye H, Heavey S, Mertzanidou T, Whitaker H, Freeman A, Patel D, Shaw GL, Sridhar A, Hawkes DJ, Punwani S, Alexander DC, Panagiotaki E.

NMR Biomed. 2019 May;32(5):e4073. doi: 10.1002/nbm.4073. Epub 2019 Feb 19.

20.

Dental Team's Role in Maternal and Child Oral Health During and After Pregnancy.

Geisinger ML, Alexander DC, Dragan IF, Mitchell SC.

Compend Contin Educ Dent. 2019 Feb;40(2):90-96; quiz 97.

PMID:
30767548
21.

Cross-scanner and cross-protocol diffusion MRI data harmonisation: A benchmark database and evaluation of algorithms.

Tax CM, Grussu F, Kaden E, Ning L, Rudrapatna U, John Evans C, St-Jean S, Leemans A, Koppers S, Merhof D, Ghosh A, Tanno R, Alexander DC, Zappalà S, Charron C, Kusmia S, Linden DE, Jones DK, Veraart J.

Neuroimage. 2019 Jul 15;195:285-299. doi: 10.1016/j.neuroimage.2019.01.077. Epub 2019 Feb 1.

22.

The metabolite repair enzyme Nit1 is a dual-targeted amidase that disposes of damaged glutathione in Arabidopsis.

Niehaus TD, Patterson JA, Alexander DC, Folz JS, Pyc M, MacTavish BS, Bruner SD, Mullen RT, Fiehn O, Hanson AD.

Biochem J. 2019 Feb 19;476(4):683-697. doi: 10.1042/BCJ20180931.

PMID:
30692244
23.

Simplified Luminal Water Imaging for the Detection of Prostate Cancer From Multiecho T2 MR Images.

Devine W, Giganti F, Johnston EW, Sidhu HS, Panagiotaki E, Punwani S, Alexander DC, Atkinson D.

J Magn Reson Imaging. 2019 Sep;50(3):910-917. doi: 10.1002/jmri.26608. Epub 2018 Dec 19.

24.

A generative model of realistic brain cells with application to numerical simulation of the diffusion-weighted MR signal.

Palombo M, Alexander DC, Zhang H.

Neuroimage. 2019 Mar;188:391-402. doi: 10.1016/j.neuroimage.2018.12.025. Epub 2018 Dec 12.

PMID:
30553045
25.

Collaborating With the Perinatal Team for Optimal Oral Health Before, During, and After a Healthy Pregnancy.

Alexander DC, Geisinger ML, Shenoy S, Dragan IF.

Compend Contin Educ Dent. 2018 Nov/Dec;39(10):678-684; quiz 685.

PMID:
30421937
26.

VERDICT-AMICO: Ultrafast fitting algorithm for non-invasive prostate microstructure characterization.

Bonet-Carne E, Johnston E, Daducci A, Jacobs JG, Freeman A, Atkinson D, Hawkes DJ, Punwani S, Alexander DC, Panagiotaki E.

NMR Biomed. 2019 Jan;32(1):e4019. doi: 10.1002/nbm.4019. Epub 2018 Oct 31.

27.

Neurite orientation and dispersion density imaging (NODDI) detects cortical and corticospinal tract degeneration in ALS.

Broad RJ, Gabel MC, Dowell NG, Schwartzman DJ, Seth AK, Zhang H, Alexander DC, Cercignani M, Leigh PN.

J Neurol Neurosurg Psychiatry. 2019 Apr;90(4):404-411. doi: 10.1136/jnnp-2018-318830. Epub 2018 Oct 25.

28.

Neurite density is reduced in the presymptomatic phase of C9orf72 disease.

Wen J, Zhang H, Alexander DC, Durrleman S, Routier A, Rinaldi D, Houot M, Couratier P, Hannequin D, Pasquier F, Zhang J, Colliot O, Le Ber I, Bertrand A; Predict to Prevent Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis (PREV-DEMALS) Study Group.

J Neurol Neurosurg Psychiatry. 2019 Apr;90(4):387-394. doi: 10.1136/jnnp-2018-318994. Epub 2018 Oct 24.

PMID:
30355607
29.

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference.

Young AL, Marinescu RV, Oxtoby NP, Bocchetta M, Yong K, Firth NC, Cash DM, Thomas DL, Dick KM, Cardoso J, van Swieten J, Borroni B, Galimberti D, Masellis M, Tartaglia MC, Rowe JB, Graff C, Tagliavini F, Frisoni GB, Laforce R Jr, Finger E, de Mendonça A, Sorbi S, Warren JD, Crutch S, Fox NC, Ourselin S, Schott JM, Rohrer JD, Alexander DC; Genetic FTD Initiative (GENFI); Alzheimer’s Disease Neuroimaging Initiative (ADNI).

Nat Commun. 2018 Oct 15;9(1):4273. doi: 10.1038/s41467-018-05892-0.

30.

Multi-modal functional MRI to explore placental function over gestation.

Hutter J, Slator PJ, Jackson L, Gomes ADS, Ho A, Story L, O'Muircheartaigh J, Teixeira RPAG, Chappell LC, Alexander DC, Rutherford MA, Hajnal JV.

Magn Reson Med. 2019 Feb;81(2):1191-1204. doi: 10.1002/mrm.27447. Epub 2018 Sep 21.

31.

Relevance of time-dependence for clinically viable diffusion imaging of the spinal cord.

Grussu F, Ianuş A, Tur C, Prados F, Schneider T, Kaden E, Ourselin S, Drobnjak I, Zhang H, Alexander DC, Gandini Wheeler-Kingshott CAM.

Magn Reson Med. 2019 Feb;81(2):1247-1264. doi: 10.1002/mrm.27463. Epub 2018 Sep 5.

32.

Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington's disease.

Byrne LM, Rodrigues FB, Johnson EB, Wijeratne PA, De Vita E, Alexander DC, Palermo G, Czech C, Schobel S, Scahill RI, Heslegrave A, Zetterberg H, Wild EJ.

Sci Transl Med. 2018 Sep 12;10(458). pii: eaat7108. doi: 10.1126/scitranslmed.aat7108.

PMID:
30209243
33.

Accurate estimation of microscopic diffusion anisotropy and its time dependence in the mouse brain.

Ianuş A, Jespersen SN, Serradas Duarte T, Alexander DC, Drobnjak I, Shemesh N.

Neuroimage. 2018 Dec;183:934-949. doi: 10.1016/j.neuroimage.2018.08.034. Epub 2018 Aug 23.

PMID:
30145206
34.

Neuroimage special issue on microstructure - Editorial.

Stikov N, Alexander DC, Pike GB.

Neuroimage. 2018 Nov 15;182:1-2. doi: 10.1016/j.neuroimage.2018.07.061. Epub 2018 Jul 29. No abstract available.

PMID:
30059732
35.

Failure of a multiplex polymerase chain reaction assay to detect IMP-27 in a clinical isolate of Morganella morganii.

Walkty A, Adam H, Tran V, Alexander DC, Boyd D, Bharat A, Karlowsky J.

Diagn Microbiol Infect Dis. 2018 Nov;92(3):194-195. doi: 10.1016/j.diagmicrobio.2018.06.011. Epub 2018 Jun 22.

PMID:
30025967
36.

Aging related cognitive changes associated with Alzheimer's disease in Down syndrome.

Firth NC, Startin CM, Hithersay R, Hamburg S, Wijeratne PA, Mok KY, Hardy J, Alexander DC; LonDownS Consortium, Strydom A.

Ann Clin Transl Neurol. 2018 May 20;5(6):741-751. doi: 10.1002/acn3.571. eCollection 2018 Jun.

37.

Laboratory testing and phylogenetic analysis during a mumps outbreak in Ontario, Canada.

L'Huillier AG, Eshaghi A, Racey CS, Ogbulafor K, Lombos E, Higgins RR, Alexander DC, Kristjanson E, Maregmen J, Gubbay JB, Mazzulli T.

Virol J. 2018 Jun 5;15(1):98. doi: 10.1186/s12985-018-0996-5.

38.

Different patterns of cortical maturation before and after 38 weeks gestational age demonstrated by diffusion MRI in vivo.

Batalle D, O'Muircheartaigh J, Makropoulos A, Kelly CJ, Dimitrova R, Hughes EJ, Hajnal JV, Zhang H, Alexander DC, Edwards AD, Counsell SJ.

Neuroimage. 2019 Jan 15;185:764-775. doi: 10.1016/j.neuroimage.2018.05.046. Epub 2018 May 23.

39.

Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI.

Jones DK, Alexander DC, Bowtell R, Cercignani M, Dell'Acqua F, McHugh DJ, Miller KL, Palombo M, Parker GJM, Rudrapatna US, Tax CMW.

Neuroimage. 2018 Nov 15;182:8-38. doi: 10.1016/j.neuroimage.2018.05.047. Epub 2018 May 22. Review.

PMID:
29793061
40.

An image-based model of brain volume biomarker changes in Huntington's disease.

Wijeratne PA, Young AL, Oxtoby NP, Marinescu RV, Firth NC, Johnson EB, Mohan A, Sampaio C, Scahill RI, Tabrizi SJ, Alexander DC.

Ann Clin Transl Neurol. 2018 Apr 2;5(5):570-582. doi: 10.1002/acn3.558. eCollection 2018 May.

41.

Progression of regional grey matter atrophy in multiple sclerosis.

Eshaghi A, Marinescu RV, Young AL, Firth NC, Prados F, Jorge Cardoso M, Tur C, De Angelis F, Cawley N, Brownlee WJ, De Stefano N, Laura Stromillo M, Battaglini M, Ruggieri S, Gasperini C, Filippi M, Rocca MA, Rovira A, Sastre-Garriga J, Geurts JJG, Vrenken H, Wottschel V, Leurs CE, Uitdehaag B, Pirpamer L, Enzinger C, Ourselin S, Gandini Wheeler-Kingshott CA, Chard D, Thompson AJ, Barkhof F, Alexander DC, Ciccarelli O.

Brain. 2018 Jun 1;141(6):1665-1677. doi: 10.1093/brain/awy088.

42.

Healthy Pregnancy: A Patient-Centered Approach to Counseling and Behavioral Change.

Geisinger ML, Dragan IF, Alexander DC.

Compend Contin Educ Dent. 2018 May;39(5):286-290; quiz 292. Review.

PMID:
29714494
43.

Data-driven models of dominantly-inherited Alzheimer's disease progression.

Oxtoby NP, Young AL, Cash DM, Benzinger TLS, Fagan AM, Morris JC, Bateman RJ, Fox NC, Schott JM, Alexander DC.

Brain. 2018 May 1;141(5):1529-1544. doi: 10.1093/brain/awy050.

44.

Cortical microstructure in young onset Alzheimer's disease using neurite orientation dispersion and density imaging.

Parker TD, Slattery CF, Zhang J, Nicholas JM, Paterson RW, Foulkes AJM, Malone IB, Thomas DL, Modat M, Cash DM, Crutch SJ, Alexander DC, Ourselin S, Fox NC, Zhang H, Schott JM.

Hum Brain Mapp. 2018 Jul;39(7):3005-3017. doi: 10.1002/hbm.24056. Epub 2018 Mar 25.

45.

Susceptibility of brain atrophy to TRIB3 in Alzheimer's disease, evidence from functional prioritization in imaging genetics.

Lorenzi M, Altmann A, Gutman B, Wray S, Arber C, Hibar DP, Jahanshad N, Schott JM, Alexander DC, Thompson PM, Ourselin S; Alzheimer’s Disease Neuroimaging Initiative.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3162-3167. doi: 10.1073/pnas.1706100115. Epub 2018 Mar 6.

46.

Microstructure Characterization of Bone Metastases from Prostate Cancer with Diffusion MRI: Preliminary Findings.

Bailey C, Collins DJ, Tunariu N, Orton MR, Morgan VA, Feiweier T, Hawkes DJ, Leach MO, Alexander DC, Panagiotaki E.

Front Oncol. 2018 Feb 16;8:26. doi: 10.3389/fonc.2018.00026. eCollection 2018.

47.

Dental Care as a Safe and Essential Part of a Healthy Pregnancy.

Dragan IF, Veglia V, Geisinger ML, Alexander DC.

Compend Contin Educ Dent. 2018 Feb;39(2):86-91; quiz 92.

PMID:
29388782
48.

Mycobacterium xenopi Genotype Associated with Clinical Phenotype in Lung Disease.

Hirama T, Marchand-Austin A, Ma J, Alexander DC, Brode SK, Marras TK, Jamieson FB.

Lung. 2018 Apr;196(2):213-217. doi: 10.1007/s00408-018-0087-9. Epub 2018 Jan 18.

PMID:
29349535
49.

Deep gray matter volume loss drives disability worsening in multiple sclerosis.

Eshaghi A, Prados F, Brownlee WJ, Altmann DR, Tur C, Cardoso MJ, De Angelis F, van de Pavert SH, Cawley N, De Stefano N, Stromillo ML, Battaglini M, Ruggieri S, Gasperini C, Filippi M, Rocca MA, Rovira A, Sastre-Garriga J, Vrenken H, Leurs CE, Killestein J, Pirpamer L, Enzinger C, Ourselin S, Wheeler-Kingshott CAMG, Chard D, Thompson AJ, Alexander DC, Barkhof F, Ciccarelli O; MAGNIMS study group.

Ann Neurol. 2018 Feb;83(2):210-222. doi: 10.1002/ana.25145. Epub 2018 Feb 6.

50.

Using diffusion MRI to discriminate areas of cortical grey matter.

Ganepola T, Nagy Z, Ghosh A, Papadopoulo T, Alexander DC, Sereno MI.

Neuroimage. 2018 Nov 15;182:456-468. doi: 10.1016/j.neuroimage.2017.12.046. Epub 2017 Dec 21.

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