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Items: 1 to 50 of 164

1.

Hospice utilization in elderly patients with brain metastases.

Mehanna EK, Catalano PJ, Cagney DN, Haas-Kogan DA, Alexander BM, Tulsky JA, Aizer AA.

J Natl Cancer Inst. 2020 Mar 12. pii: djaa036. doi: 10.1093/jnci/djaa036. [Epub ahead of print]

PMID:
32163145
2.

Racial disparities in supportive medication use among older patients with brain metastases: A population-based analysis.

Lamba N, Mehanna E, Kearney RB, Catalano PJ, Haas-Kogan DA, Alexander BM, Cagney DN, Lee KA, Aizer AA.

Neuro Oncol. 2020 Mar 9. pii: noaa054. doi: 10.1093/neuonc/noaa054. [Epub ahead of print]

PMID:
32149345
3.

Melanomas with activating RAF1 fusions: clinical, histopathologic, and molecular profiles.

Williams EA, Shah N, Montesion M, Sharaf R, Pavlick DC, Sokol ES, Alexander BM, Venstrom JM, Elvin JA, Ross JS, Tse JY, Mochel MC.

Mod Pathol. 2020 Mar 2. doi: 10.1038/s41379-020-0510-7. [Epub ahead of print]

PMID:
32123303
4.

Pathological complete response after neoadjuvant chemotherapy and impact on breast cancer recurrence and survival: a comprehensive meta-analysis.

Spring LM, Fell G, Arfe A, Sharma C, Greenup RA, Reynolds KL, Smith BL, Alexander BM, Moy B, Isakoff SJ, Parmigiani G, Trippa L, Bardia A.

Clin Cancer Res. 2020 Feb 11. pii: clincanres.3492.2019. doi: 10.1158/1078-0432.CCR-19-3492. [Epub ahead of print]

PMID:
32046998
5.

Urothelial cancer harbours EGFR and HER2 amplifications and exon 20 insertions.

Madison RW, Gupta SV, Elamin YY, Lin DI, Pal SK, Necchi A, Miller VA, Ross JS, Chung JH, Alexander BM, Schrock AB, Heymach JV, Reddy P, Ali SM.

BJU Int. 2020 Jan 27. doi: 10.1111/bju.15006. [Epub ahead of print]

PMID:
31985116
6.

Comprehensive Assessment of Immuno-oncology Biomarkers in Adenocarcinoma, Urothelial Carcinoma, and Squamous-cell Carcinoma of the Bladder.

Necchi A, Madison R, Raggi D, Jacob JM, Bratslavsky G, Shapiro O, Elvin JA, Vergilio JA, Killian JK, Ngo N, Ramkissoon S, Severson E, Hemmerich AC, Huang R, Ali SM, Chung JH, Reddy P, Miller VA, Schrock AB, Gay LM, Alexander BM, Grivas P, Ross JS.

Eur Urol. 2020 Apr;77(4):548-556. doi: 10.1016/j.eururo.2020.01.003. Epub 2020 Jan 17.

PMID:
31959546
7.

New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures.

Boxer AL, Gold M, Feldman H, Boeve BF, Dickinson SL, Fillit H, Ho C, Paul R, Pearlman R, Sutherland M, Verma A, Arneric SP, Alexander BM, Dickerson BC, Dorsey ER, Grossman M, Huey ED, Irizarry MC, Marks WJ, Masellis M, McFarland F, Niehoff D, Onyike CU, Paganoni S, Panzara MA, Rockwood K, Rohrer JD, Rosen H, Schuck RN, Soares HD, Tatton N.

Alzheimers Dement. 2020 Jan;16(1):131-143. doi: 10.1016/j.jalz.2019.06.4956. Epub 2020 Jan 6.

PMID:
31668596
8.

Atypical Histopathological Features and the Risk of Treatment Failure in Nonmalignant Meningiomas: A Multi-Institutional Analysis.

Lamba N, Hwang WL, Kim DW, Niemierko A, Marciscano AE, Mehan WA Jr, Benayoun MD, Curry WT, Barker FG 2nd, Martuza RL, Dunn IF, Claus E, Bi WL, Aizer AA, Alexander BM, Oh KS, Loeffler JS, Shih HA.

World Neurosurg. 2020 Jan;133:e804-e812. doi: 10.1016/j.wneu.2019.10.002. Epub 2019 Oct 9.

PMID:
31605839
9.

Deviation from the Proportional Hazards Assumption in Randomized Phase 3 Clinical Trials in Oncology: Prevalence, Associated Factors, and Implications.

Rahman R, Fell G, Ventz S, Arfé A, Vanderbeek AM, Trippa L, Alexander BM.

Clin Cancer Res. 2019 Nov 1;25(21):6339-6345. doi: 10.1158/1078-0432.CCR-18-3999. Epub 2019 Jul 25.

PMID:
31345838
10.

Barriers to Accrual and Enrollment in Brain Tumor Trials.

Lee EQ, Chukwueke UN, Hervey-Jumper SL, de Groot JF, Leone JP, Armstrong TS, Chang SM, Arons D, Oliver K, Verble K, Musella A, Willmarth N, Alexander BM, Bates A, Doherty L, Galanis E, Gaffey S, Halkin T, Friday BE, Fouladi M, Lin NU, Macdonald D, Mehta MP, Penas-Prado M, Vogelbaum MA, Sahebjam S, Sandak D, van den Bent M, Weller M, Reardon DA, Wen PY.

Neuro Oncol. 2019 Jun 7. pii: noz104. doi: 10.1093/neuonc/noz104. [Epub ahead of print]

PMID:
31175826
11.

Design and Evaluation of an External Control Arm Using Prior Clinical Trials and Real-World Data.

Ventz S, Lai A, Cloughesy TF, Wen PY, Trippa L, Alexander BM.

Clin Cancer Res. 2019 Aug 15;25(16):4993-5001. doi: 10.1158/1078-0432.CCR-19-0820. Epub 2019 Jun 7.

12.

To randomize, or not to randomize, that is the question: using data from prior clinical trials to guide future designs.

Vanderbeek AM, Ventz S, Rahman R, Fell G, Cloughesy TF, Wen PY, Trippa L, Alexander BM.

Neuro Oncol. 2019 Oct 9;21(10):1239-1249. doi: 10.1093/neuonc/noz097.

PMID:
31155679
13.

Video-Based Preconception Counseling for Women Living With HIV.

Alexander BM, Farel CE, Rahangdale L, McGee K, Thompson J, Barley K, Harmon JL.

J Assoc Nurses AIDS Care. 2020 Jan-Feb;31(1):66-70. doi: 10.1097/JNC.0000000000000081. No abstract available.

PMID:
31094867
14.

Breast cancer subtype and intracranial recurrence patterns after brain-directed radiation for brain metastases.

Cagney DN, Lamba N, Montoya S, Li P, Besse L, Martin AM, Brigell RH, Catalano PJ, Brown PD, Leone JP, Tanguturi SK, Haas-Kogan DA, Alexander BM, Lin NU, Aizer AA.

Breast Cancer Res Treat. 2019 Jul;176(1):171-179. doi: 10.1007/s10549-019-05236-6. Epub 2019 Apr 13.

PMID:
30982195
15.

Divining responder populations from survival data.

Rahman R, Ventz S, Fell G, Vanderbeek AM, Trippa L, Alexander BM.

Ann Oncol. 2019 Jun 1;30(6):1005-1013. doi: 10.1093/annonc/mdz087.

16.

Association of Neurosurgical Resection With Development of Pachymeningeal Seeding in Patients With Brain Metastases.

Cagney DN, Lamba N, Sinha S, Catalano PJ, Bi WL, Alexander BM, Aizer AA.

JAMA Oncol. 2019 May 1;5(5):703-709. doi: 10.1001/jamaoncol.2018.7204.

17.

Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial.

Wen PY, Touat M, Alexander BM, Mellinghoff IK, Ramkissoon S, McCluskey CS, Pelton K, Haidar S, Basu SS, Gaffey SC, Brown LE, Martinez-Ledesma JE, Wu S, Kim J, Wei W, Park MA, Huse JT, Kuhn JG, Rinne ML, Colman H, Agar NYR, Omuro AM, DeAngelis LM, Gilbert MR, de Groot JF, Cloughesy TF, Chi AS, Roberts TM, Zhao JJ, Lee EQ, Nayak L, Heath JR, Horky LL, Batchelor TT, Beroukhim R, Chang SM, Ligon AH, Dunn IF, Koul D, Young GS, Prados MD, Reardon DA, Yung WKA, Ligon KL.

J Clin Oncol. 2019 Mar 20;37(9):741-750. doi: 10.1200/JCO.18.01207. Epub 2019 Feb 4.

18.

Local control after brain-directed radiation in patients with cystic versus solid brain metastases.

Brigell RH, Cagney DN, Martin AM, Besse LA, Catalano PJ, Lee EQ, Wen PY, Brown PD, Phillips JG, Pashtan IM, Tanguturi SK, Haas-Kogan DA, Alexander BM, Aizer AA.

J Neurooncol. 2019 Apr;142(2):355-363. doi: 10.1007/s11060-019-03106-1. Epub 2019 Feb 4.

PMID:
30715665
19.

Bayesian Adaptive Randomization in Dose-Finding Trials.

Ventz S, Alexander BM, Trippa L.

JAMA Netw Open. 2018 Dec 7;1(8):e186075. doi: 10.1001/jamanetworkopen.2018.6075. No abstract available.

20.

The impact of histopathology and NAB2-STAT6 fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma.

Fritchie K, Jensch K, Moskalev EA, Caron A, Jenkins S, Link M, Brown PD, Rodriguez FJ, Guajardo A, Brat D, Velázquez Vega JE, Perry A, Wu A, Raleigh DR, Santagata S, Louis DN, Brastianos PK, Kaplan A, Alexander BM, Rossi S, Ferrarese F, Haller F, Giannini C.

Acta Neuropathol. 2019 Feb;137(2):307-319. doi: 10.1007/s00401-018-1952-6. Epub 2018 Dec 24.

21.

Neurosurgical Resection and Stereotactic Radiation Versus Stereotactic Radiation Alone in Patients with a Single or Solitary Brain Metastasis.

Lamba N, Cagney DN, Brigell RH, Martin AM, Besse LA, Catalano PJ, Phillips JG, Pashtan IM, Bi WL, Claus EB, Golby AJ, Dunn IF, Smith TR, Tanguturi SK, Haas-Kogan DA, Alexander BM, Aizer AA.

World Neurosurg. 2019 Feb;122:e1557-e1561. doi: 10.1016/j.wneu.2018.11.100. Epub 2018 Nov 22.

PMID:
30471438
22.

Comparison of Local Control of Brain Metastases With Stereotactic Radiosurgery vs Surgical Resection: A Secondary Analysis of a Randomized Clinical Trial.

Churilla TM, Chowdhury IH, Handorf E, Collette L, Collette S, Dong Y, Alexander BM, Kocher M, Soffietti R, Claus EB, Weiss SE.

JAMA Oncol. 2019 Feb 1;5(2):243-247. doi: 10.1001/jamaoncol.2018.4610.

23.

The Impact of Radiation Therapy on Lymphocyte Count and Survival in Metastatic Cancer Patients Receiving PD-1 Immune Checkpoint Inhibitors.

Pike LRG, Bang A, Mahal BA, Taylor A, Krishnan M, Spektor A, Cagney DN, Aizer AA, Alexander BM, Rahma O, Balboni T, Ott PA, Hodi FS, Schoenfeld JD.

Int J Radiat Oncol Biol Phys. 2019 Jan 1;103(1):142-151. doi: 10.1016/j.ijrobp.2018.09.010. Epub 2018 Sep 15.

PMID:
30227198
24.

Effects of maternal obesity on maternal and fetal plasma concentrations of adiponectin and expression of adiponectin and its receptor genes in cotyledonary and adipose tissues at mid- and late-gestation in sheep.

Fensterseifer SR, Austin KJ, Ford SP, Alexander BM.

Anim Reprod Sci. 2018 Oct;197:231-239. doi: 10.1016/j.anireprosci.2018.08.033. Epub 2018 Aug 26.

PMID:
30172606
25.

Neurologic Complications of Radiation Therapy.

Tanguturi SK, Alexander BM.

Neurol Clin. 2018 Aug;36(3):599-625. doi: 10.1016/j.ncl.2018.04.012. Epub 2018 Jun 15. Review.

PMID:
30072073
26.

Implications of Screening for Brain Metastases in Patients With Breast Cancer and Non-Small Cell Lung Cancer.

Cagney DN, Martin AM, Catalano PJ, Brown PD, Alexander BM, Lin NU, Aizer AA.

JAMA Oncol. 2018 Jul 1;4(7):1001-1003. doi: 10.1001/jamaoncol.2018.0813. No abstract available.

27.

Validation of postoperative residual contrast-enhancing tumor volume as an independent prognostic factor for overall survival in newly diagnosed glioblastoma.

Ellingson BM, Abrey LE, Nelson SJ, Kaufmann TJ, Garcia J, Chinot O, Saran F, Nishikawa R, Henriksson R, Mason WP, Wick W, Butowski N, Ligon KL, Gerstner ER, Colman H, de Groot J, Chang S, Mellinghoff I, Young RJ, Alexander BM, Colen R, Taylor JW, Arrillaga-Romany I, Mehta A, Huang RY, Pope WB, Reardon D, Batchelor T, Prados M, Galanis E, Wen PY, Cloughesy TF.

Neuro Oncol. 2018 Aug 2;20(9):1240-1250. doi: 10.1093/neuonc/noy053.

28.

Platform trials arrive on time for glioblastoma.

Alexander BM, Cloughesy TF.

Neuro Oncol. 2018 May 18;20(6):723-725. doi: 10.1093/neuonc/noy040. No abstract available.

30.

Hazards of Hazard Ratios - Deviations from Model Assumptions in Immunotherapy.

Alexander BM, Schoenfeld JD, Trippa L.

N Engl J Med. 2018 Mar 22;378(12):1158-1159. doi: 10.1056/NEJMc1716612. No abstract available.

PMID:
29562148
31.

The clinical trials landscape for glioblastoma: is it adequate to develop new treatments?

Vanderbeek AM, Rahman R, Fell G, Ventz S, Chen T, Redd R, Parmigiani G, Cloughesy TF, Wen PY, Trippa L, Alexander BM.

Neuro Oncol. 2018 Jul 5;20(8):1034-1043. doi: 10.1093/neuonc/noy027.

32.

Impact of pemetrexed on intracranial disease control and radiation necrosis in patients with brain metastases from non-small cell lung cancer receiving stereotactic radiation.

Cagney DN, Martin AM, Catalano PJ, Reitman ZJ, Mezochow GA, Lee EQ, Wen PY, Weiss SE, Brown PD, Ahluwalia MS, Arvold ND, Tanguturi SK, Haas-Kogan DA, Alexander BM, Redig AJ, Aizer AA.

Radiother Oncol. 2018 Mar;126(3):511-518. doi: 10.1016/j.radonc.2018.01.005. Epub 2018 Feb 3.

PMID:
29398153
33.

Immunotherapy and Symptomatic Radiation Necrosis in Patients With Brain Metastases Treated With Stereotactic Radiation.

Martin AM, Cagney DN, Catalano PJ, Alexander BM, Redig AJ, Schoenfeld JD, Aizer AA.

JAMA Oncol. 2018 Aug 1;4(8):1123-1124. doi: 10.1001/jamaoncol.2017.3993. No abstract available.

34.

Clinical trial design for local therapies for brain metastases: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group.

Alexander BM, Brown PD, Ahluwalia MS, Aoyama H, Baumert BG, Chang SM, Gaspar LE, Kalkanis SN, Macdonald DR, Mehta MP, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wefel JS, Lee EQ, Wen PY; Response Assessment in Neuro-Oncology (RANO) group.

Lancet Oncol. 2018 Jan;19(1):e33-e42. doi: 10.1016/S1470-2045(17)30692-7. Review.

PMID:
29304360
35.

The FDA NIH Biomarkers, EndpointS, and other Tools (BEST) resource in neuro-oncology.

Cagney DN, Sul J, Huang RY, Ligon KL, Wen PY, Alexander BM.

Neuro Oncol. 2018 Aug 2;20(9):1162-1172. doi: 10.1093/neuonc/nox242. Review.

36.

Future cancer research priorities in the USA: a Lancet Oncology Commission.

Jaffee EM, Dang CV, Agus DB, Alexander BM, Anderson KC, Ashworth A, Barker AD, Bastani R, Bhatia S, Bluestone JA, Brawley O, Butte AJ, Coit DG, Davidson NE, Davis M, DePinho RA, Diasio RB, Draetta G, Frazier AL, Futreal A, Gambhir SS, Ganz PA, Garraway L, Gerson S, Gupta S, Heath J, Hoffman RI, Hudis C, Hughes-Halbert C, Ibrahim R, Jadvar H, Kavanagh B, Kittles R, Le QT, Lippman SM, Mankoff D, Mardis ER, Mayer DK, McMasters K, Meropol NJ, Mitchell B, Naredi P, Ornish D, Pawlik TM, Peppercorn J, Pomper MG, Raghavan D, Ritchie C, Schwarz SW, Sullivan R, Wahl R, Wolchok JD, Wong SL, Yung A.

Lancet Oncol. 2017 Nov;18(11):e653-e706. doi: 10.1016/S1470-2045(17)30698-8. Epub 2017 Oct 31. Review.

37.

Radiographic prediction of meningioma grade by semantic and radiomic features.

Coroller TP, Bi WL, Huynh E, Abedalthagafi M, Aizer AA, Greenwald NF, Parmar C, Narayan V, Wu WW, Miranda de Moura S, Gupta S, Beroukhim R, Wen PY, Al-Mefty O, Dunn IF, Santagata S, Alexander BM, Huang RY, Aerts HJWL.

PLoS One. 2017 Nov 16;12(11):e0187908. doi: 10.1371/journal.pone.0187908. eCollection 2017.

38.

Sun exposure in pigs increases the vitamin D nutritional quality of pork.

Larson-Meyer DE, Ingold BC, Fensterseifer SR, Austin KJ, Wechsler PJ, Hollis BW, Makowski AJ, Alexander BM.

PLoS One. 2017 Nov 14;12(11):e0187877. doi: 10.1371/journal.pone.0187877. eCollection 2017.

39.

The impact of different stereotactic radiation therapy regimens for brain metastases on local control and toxicity.

Jimenez RB, Alexander BM, Mahadevan A, Niemierko A, Rajakesari S, Arvold ND, Floyd SR, Oh KS, Loeffler JS, Shih HA.

Adv Radiat Oncol. 2017 Jun 6;2(3):391-397. doi: 10.1016/j.adro.2017.05.008. eCollection 2017 Jul-Sep.

40.

Tyrosine hydroxylase in the ventral tegmental area of rams with high or low libido-A role for dopamine.

Kramer AC, Mirto AJ, Austin KJ, Roselli CE, Alexander BM.

Anim Reprod Sci. 2017 Dec;187:152-158. doi: 10.1016/j.anireprosci.2017.10.019. Epub 2017 Oct 31.

41.

Evaluation of an improved prototype mini-baghouse to control the release of respirable crystalline silica from sand movers.

Alexander BM, Esswein EJ, Gressel MG, Kratzer JL, Feng HA, Miller AL, Cauda E, Heil G.

J Occup Environ Hyg. 2018 Jan;15(1):24-37. doi: 10.1080/15459624.2017.1376068.

PMID:
29053936
42.

Innovation Incentives and Biomarkers.

Stern AD, Alexander BM, Chandra A.

Clin Pharmacol Ther. 2018 Jan;103(1):34-36. doi: 10.1002/cpt.876. Epub 2017 Oct 16.

PMID:
29034452
43.

Salvage re-irradiation for recurrent high-grade glioma and comparison to bevacizumab alone.

Arvold ND, Shi DD, Aizer AA, Norden AD, Reardon DA, Lee EQ, Nayak L, Dunn IF, Golby AJ, Johnson MD, Claus EB, Chiocca EA, Ligon KL, Wen PY, Alexander BM.

J Neurooncol. 2017 Dec;135(3):581-591. doi: 10.1007/s11060-017-2611-9. Epub 2017 Oct 3.

PMID:
28975467
44.

Whole brain radiotherapy after stereotactic radiosurgery or surgical resection among patients with one to three brain metastases and favorable prognoses: a secondary analysis of EORTC 22952-26001.

Churilla TM, Handorf E, Collette S, Collette L, Dong Y, Aizer AA, Kocher M, Soffietti R, Alexander BM, Weiss SE.

Ann Oncol. 2017 Oct 1;28(10):2588-2594. doi: 10.1093/annonc/mdx332.

45.

Prophylactic cranial irradiation in patients with extensive-stage small cell lung cancer.

Aizer AA, Mak R, Alexander BM.

Neuro Oncol. 2017 Aug 1;19(8):1015-1016. doi: 10.1093/neuonc/nox113. No abstract available.

46.

Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE.

Alexander BM, Ba S, Berger MS, Berry DA, Cavenee WK, Chang SM, Cloughesy TF, Jiang T, Khasraw M, Li W, Mittman R, Poste GH, Wen PY, Yung WKA, Barker AD; GBM AGILE Network.

Clin Cancer Res. 2018 Feb 15;24(4):737-743. doi: 10.1158/1078-0432.CCR-17-0764. Epub 2017 Aug 16. Review.

47.

The cost and value of glioblastoma therapy.

Cagney DN, Alexander BM.

Expert Rev Anticancer Ther. 2017 Aug;17(8):657-659. doi: 10.1080/14737140.2017.1351355. Epub 2017 Jul 13. No abstract available.

PMID:
28689438
48.

Adult Glioblastoma.

Alexander BM, Cloughesy TF.

J Clin Oncol. 2017 Jul 20;35(21):2402-2409. doi: 10.1200/JCO.2017.73.0119. Epub 2017 Jun 22. Review.

PMID:
28640706
49.

Designing Clinical Trials That Accept New Arms: An Example in Metastatic Breast Cancer.

Ventz S, Alexander BM, Parmigiani G, Gelber RD, Trippa L.

J Clin Oncol. 2017 Sep 20;35(27):3160-3168. doi: 10.1200/JCO.2016.70.1169. Epub 2017 May 22.

PMID:
28530853
50.

Erratum to: Rapid progression of intracranial melanoma metastases controlled with combined BRAF/MEK inhibition after discontinuation of therapy: a clinical challenge.

Cagney DN, Alexander BM, Hodi FS, Buchbinder EI, Ott PA, Aizer AA.

J Neurooncol. 2017 May;133(1):221. doi: 10.1007/s11060-017-2485-x. No abstract available.

PMID:
28527005

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