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Charting the Path Forward Development, Goals and Initiatives of the 2019 IDSA Strategic Plan.

Sears CL, File TM, Alexander BD, McQuillen DP, MacIntyre AT, Allen UD, Colasanti JA, Siddiqui J, Reveles KR, Busky C.

Clin Infect Dis. 2019 Oct 17. pii: ciz1040. doi: 10.1093/cid/ciz1040. [Epub ahead of print]


Oral and Inhaled Ribavirin Treatment for Respiratory Syncytial Virus Infection in Lung Transplant Recipients.

Permpalung N, Thaniyavarn T, Saullo JL, Arif S, Miller RA, Reynolds JM, Alexander BD.

Transplantation. 2019 Sep 24. doi: 10.1097/TP.0000000000002985. [Epub ahead of print]


Surfactant modulated interactions of hydrophobically modified ethoxylated urethane (HEUR) polymers with penetrable surfaces.

Ibrahim MS, King S, Murray M, Szczygiel A, Alexander BD, Griffiths PC.

J Colloid Interface Sci. 2019 Sep 15;552:9-16. doi: 10.1016/j.jcis.2019.05.035. Epub 2019 May 11.


Infections after kidney transplantation. Does age matter?

Hemmersbach-Miller M, Alexander BD, Sudan DL, Pieper C, Schmader KE.

Clin Transplant. 2019 Apr;33(4):e13516. doi: 10.1111/ctr.13516. Epub 2019 Mar 28.


Invasive Fungal Infection after Lung Transplantation: Epidemiology in the Setting of Antifungal Prophylaxis.

Baker AW, Maziarz EK, Arnold CJ, Johnson MD, Workman AD, Reynolds JM, Perfect JR, Alexander BD.

Clin Infect Dis. 2019 Feb 25. pii: ciz156. doi: 10.1093/cid/ciz156. [Epub ahead of print]


Surfactant modulated interaction of hydrophobically modified ethoxylated urethane (HEUR) polymers with impenetrable surfaces.

Ibrahim MS, Rogers S, Mahmoudi N, Murray M, Szczygiel A, Green B, Alexander BD, Griffiths PC.

J Colloid Interface Sci. 2019 Mar 15;539:126-134. doi: 10.1016/j.jcis.2018.12.059. Epub 2018 Dec 15.


Single-center analysis of infectious complications in older adults during the first year after kidney transplantation.

Hemmersbach-Miller M, Alexander BD, Sudan DL, Pieper C, Schmader KE.

Eur J Clin Microbiol Infect Dis. 2019 Jan;38(1):141-148. doi: 10.1007/s10096-018-3405-5. Epub 2018 Oct 23.


Fluoroquinolone prophylaxis reduces febrile neutropenia, bloodstream infections from mucosal translocations, and intensive care admissions in high risk hematological patients, a single center experience.

Chung SJ, Miller RA, Permpalung N, Baker AW, Diehl LF, Rizzieri DA, Alexander BD.

Leuk Lymphoma. 2019 Feb;60(2):488-492. doi: 10.1080/10428194.2018.1488252. Epub 2018 Aug 21. No abstract available.


Production of membrane proteins for characterisation of their pheromone-sensing and antimicrobial resistance functions.

Azam AA, Kinder JM, Khan GN, Alase A, Ma P, Liu Y, Ault JR, Henderson PJF, Chowdhry BZ, Alexander BD, Harding SE, Phillips-Jones MK.

Eur Biophys J. 2018 Oct;47(7):723-737. doi: 10.1007/s00249-018-1325-z. Epub 2018 Jul 31.


Studying the interaction of hydrophobically modified ethoxylated urethane (HEUR) polymers with sodium dodecylsulfate (SDS) in concentrated polymer solutions.

Ibrahim MS, Valencony J, King S, Murray M, Szczygiel A, Alexander BD, Griffiths PC.

J Colloid Interface Sci. 2018 Nov 1;529:588-598. doi: 10.1016/j.jcis.2018.06.042. Epub 2018 Jun 20.


Clinical and Genomic Characterization of Recurrent Enterococcal Bloodstream Infection in Patients With Acute Leukemia.

Messina JA, Sinha R, Starr K, Arshad M, Alexander BD, Chao NJ, Sung AD.

Open Forum Infect Dis. 2018 May 5;5(6):ofy107. doi: 10.1093/ofid/ofy107. eCollection 2018 Jun.


A Randomized, Placebo-controlled Trial of Fidaxomicin for Prophylaxis of Clostridium difficile-associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation.

Mullane KM, Winston DJ, Nooka A, Morris MI, Stiff P, Dugan MJ, Holland H, Gregg K, Adachi JA, Pergam SA, Alexander BD, Dubberke ER, Broyde N, Gorbach SL, Sears PS.

Clin Infect Dis. 2019 Jan 7;68(2):196-203. doi: 10.1093/cid/ciy484. Erratum in: Clin Infect Dis. 2019 Mar 19;68(7):1254.


Genomic characterization of recurrent mold infections in thoracic transplant recipients.

Messina JA, Wolfe CR, Hemmersbach-Miller M, Milano C, Todd JL, Reynolds J, Alexander BD, Schell WA, Cuomo CA, Perfect JR.

Transpl Infect Dis. 2018 Oct;20(5):e12935. doi: 10.1111/tid.12935. Epub 2018 Jun 19.


A Mycoses Study Group International Prospective Study of Phaeohyphomycosis: An Analysis of 99 Proven/Probable Cases.

Revankar SG, Baddley JW, Chen SC, Kauffman CA, Slavin M, Vazquez JA, Seas C, Morris MI, Nguyen MH, Shoham S, Thompson GR 3rd, Alexander BD, Simkins J, Ostrosky-Zeichner L, Mullane K, Alangaden G, Andes DR, Cornely OA, Wahlers K, Lockhart SR, Pappas PG.

Open Forum Infect Dis. 2017 Sep 26;4(4):ofx200. doi: 10.1093/ofid/ofx200. eCollection 2017 Fall.


Circular dichroism studies of low molecular weight hydrogelators: The use of SRCD and addressing practical issues.

Sitsanidis ED, Piras CC, Alexander BD, Siligardi G, Jávorfi T, Hall AJ, Edwards AA.

Chirality. 2018 Jun;30(6):708-718. doi: 10.1002/chir.22850. Epub 2018 Apr 12.


3D printed microneedles for insulin skin delivery.

Pere CPP, Economidou SN, Lall G, Ziraud C, Boateng JS, Alexander BD, Lamprou DA, Douroumis D.

Int J Pharm. 2018 Jun 15;544(2):425-432. doi: 10.1016/j.ijpharm.2018.03.031. Epub 2018 Mar 16.


Antifungal Activity of SCY-078 and Standard Antifungal Agents against 178 Clinical Isolates of Resistant and Susceptible Candida Species.

Schell WA, Jones AM, Borroto-Esoda K, Alexander BD.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01102-17. doi: 10.1128/AAC.01102-17. Print 2017 Nov.


Facet-Dependent Interactions of Islet Amyloid Polypeptide with Gold Nanoparticles: Implications for Fibril Formation and Peptide-Induced Lipid Membrane Disruption.

Wang ST, Lin Y, Todorova N, Xu Y, Mazo M, Rana S, Leonardo V, Amdursky N, Spicer CD, Alexander BD, Edwards AA, Matthews SJ, Yarovsky I, Stevens MM.

Chem Mater. 2017 Feb 28;29(4):1550-1560. doi: 10.1021/acs.chemmater.6b04144. Epub 2017 Feb 13.


Establishment and Use of Epidemiological Cutoff Values for Molds and Yeasts by Use of the Clinical and Laboratory Standards Institute M57 Standard.

Lockhart SR, Ghannoum MA, Alexander BD.

J Clin Microbiol. 2017 May;55(5):1262-1268. doi: 10.1128/JCM.02416-16. Epub 2017 Feb 15. Review.


Changing Epidemiology of Invasive Mold Infections in Patients Receiving Azole Prophylaxis.

Lamoth F, Chung SJ, Damonti L, Alexander BD.

Clin Infect Dis. 2017 Jun 1;64(11):1619-1621. doi: 10.1093/cid/cix130. Erratum in: Clin Infect Dis. 2017 Oct 15;65(8):1431-1433.


Two-Phase Hospital-Associated Outbreak of Mycobacterium abscessus: Investigation and Mitigation.

Baker AW, Lewis SS, Alexander BD, Chen LF, Wallace RJ Jr, Brown-Elliott BA, Isaacs PJ, Pickett LC, Patel CB, Smith PK, Reynolds JM, Engel J, Wolfe CR, Milano CA, Schroder JN, Davis RD, Hartwig MG, Stout JE, Strittholt N, Maziarz EK, Saullo JH, Hazen KC, Walczak RJ Jr, Vasireddy R, Vasireddy S, McKnight CM, Anderson DJ, Sexton DJ.

Clin Infect Dis. 2017 Apr 1;64(7):902-911. doi: 10.1093/cid/ciw877.


Fungal CYP51 Inhibitors VT-1161 and VT-1129 Exhibit Strong In Vitro Activity against Candida glabrata and C. krusei Isolates Clinically Resistant to Azole and Echinocandin Antifungal Compounds.

Schell WA, Jones AM, Garvey EP, Hoekstra WJ, Schotzinger RJ, Alexander BD.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e01817-16. doi: 10.1128/AAC.01817-16. Print 2017 Mar.


Selective complexation of divalent cations by a cyclic α,β-peptoid hexamer: a spectroscopic and computational study.

De Santis E, Edwards AA, Alexander BD, Holder SJ, Biesse-Martin AS, Nielsen BV, Mistry D, Waters L, Siligardi G, Hussain R, Faure S, Taillefumier C.

Org Biomol Chem. 2016 Dec 7;14(48):11371-11380.


Diagnosis of Capnocytophaga canimorsus Sepsis by Whole-Genome Next-Generation Sequencing.

Abril MK, Barnett AS, Wegermann K, Fountain E, Strand A, Heyman BM, Blough BA, Swaminathan AC, Sharma-Kuinkel B, Ruffin F, Alexander BD, McCall CM, Costa SF, Arcasoy MO, Hong DK, Blauwkamp TA, Kertesz M, Fowler VG Jr, Kraft BD.

Open Forum Infect Dis. 2016 Jul 12;3(3):ofw144. eCollection 2016 Sep.


Hemorrhagic Herpes Simplex Virus Type 1 Nephritis: An Unusual Cause of Acute Allograft Dysfunction.

Hemmersbach-Miller M, Duronville J, Sethi S, Miller SE, Howell DN, Henshaw N, Alexander BD, Roberts JK.

Am J Transplant. 2017 Jan;17(1):287-291. doi: 10.1111/ajt.14022. Epub 2016 Sep 14.


Monitoring real time polymorphic transformation of sulfanilamide by diffuse reflectance visible spectroscopy.

Ehiwe TO, Alexander BD, Mitchell JC, Snowden MJ, Waters LJ.

J Pharm Anal. 2016 Jun;6(3):179-183. doi: 10.1016/j.jpha.2015.12.002. Epub 2016 Jan 8.


Solid-state flurbiprofen and methyl-β-cyclodextrin inclusion complexes prepared using a single-step, organic solvent-free supercritical fluid process.

Rudrangi SR, Kaialy W, Ghori MU, Trivedi V, Snowden MJ, Alexander BD.

Eur J Pharm Biopharm. 2016 Jul;104:164-70. doi: 10.1016/j.ejpb.2016.04.024. Epub 2016 May 7.


Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance.

Healey KR, Zhao Y, Perez WB, Lockhart SR, Sobel JD, Farmakiotis D, Kontoyiannis DP, Sanglard D, Taj-Aldeen SJ, Alexander BD, Jimenez-Ortigosa C, Shor E, Perlin DS.

Nat Commun. 2016 Mar 29;7:11128. doi: 10.1038/ncomms11128.


An in vitro evaluation of epigallocatechin gallate (eGCG) as a biocompatible inhibitor of ricin toxin.

Dyer PD, Kotha AK, Gollings AS, Shorter SA, Shepherd TR, Pettit MW, Alexander BD, Getti GT, El-Daher S, Baillie L, Richardson SC.

Biochim Biophys Acta. 2016 Jul;1860(7):1541-50. doi: 10.1016/j.bbagen.2016.03.024. Epub 2016 Mar 23.


Role of Antifungal Susceptibility Testing in Non-Aspergillus Invasive Mold Infections.

Lamoth F, Damonti L, Alexander BD.

J Clin Microbiol. 2016 Jun;54(6):1638-1640. doi: 10.1128/JCM.00318-16. Epub 2016 Mar 23.


The 2015 International Society for Heart and Lung Transplantation Guidelines for the management of fungal infections in mechanical circulatory support and cardiothoracic organ transplant recipients: Executive summary.

Husain S, Sole A, Alexander BD, Aslam S, Avery R, Benden C, Billaud EM, Chambers D, Danziger-Isakov L, Fedson S, Gould K, Gregson A, Grossi P, Hadjiliadis D, Hopkins P, Luong ML, Marriott DJE, Monforte V, Muñoz P, Pasqualotto AC, Roman A, Silveira FP, Teuteberg J, Weigt S, Zaas AK, Zuckerman A, Morrissey O.

J Heart Lung Transplant. 2016 Mar;35(3):261-282. doi: 10.1016/j.healun.2016.01.007. Epub 2016 Jan 19. No abstract available.


CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival.

Swamydas M, Gao JL, Break TJ, Johnson MD, Jaeger M, Rodriguez CA, Lim JK, Green NM, Collar AL, Fischer BG, Lee CC, Perfect JR, Alexander BD, Kullberg BJ, Netea MG, Murphy PM, Lionakis MS.

Sci Transl Med. 2016 Jan 20;8(322):322ra10. doi: 10.1126/scitranslmed.aac7718.


Improved Detection of Invasive Pulmonary Aspergillosis Arising during Leukemia Treatment Using a Panel of Host Response Proteins and Fungal Antigens.

Brasier AR, Zhao Y, Spratt HM, Wiktorowicz JE, Ju H, Wheat LJ, Baden L, Stafford S, Wu Z, Issa N, Caliendo AM, Denning DW, Soman K, Clancy CJ, Nguyen MH, Sugrue MW, Alexander BD, Wingard JR.

PLoS One. 2015 Nov 18;10(11):e0143165. doi: 10.1371/journal.pone.0143165. eCollection 2015.


Preparation of olanzapine and methyl-β-cyclodextrin complexes using a single-step, organic solvent-free supercritical fluid process: An approach to enhance the solubility and dissolution properties.

Rudrangi SR, Trivedi V, Mitchell JC, Wicks SR, Alexander BD.

Int J Pharm. 2015 Oct 15;494(1):408-16. doi: 10.1016/j.ijpharm.2015.08.062. Epub 2015 Aug 24.


Comparing Etest and Broth Microdilution for Antifungal Susceptibility Testing of the Most-Relevant Pathogenic Molds.

Lamoth F, Alexander BD.

J Clin Microbiol. 2015 Oct;53(10):3176-81. doi: 10.1128/JCM.00925-15. Epub 2015 Jul 22.


Phaeohyphomycosis in transplant recipients: Results from the Transplant Associated Infection Surveillance Network (TRANSNET).

McCarty TP, Baddley JW, Walsh TJ, Alexander BD, Kontoyiannis DP, Perl TM, Walker R, Patterson TF, Schuster MG, Lyon GM, Wingard JR, Andes DR, Park BJ, Brandt ME, Pappas PG; TRANSNET Investigators.

Med Mycol. 2015 Jun;53(5):440-6. doi: 10.1093/mmy/myv018. Epub 2015 Apr 23.


Antifungal activities of SCY-078 (MK-3118) and standard antifungal agents against clinical non-Aspergillus mold isolates.

Lamoth F, Alexander BD.

Antimicrob Agents Chemother. 2015 Jul;59(7):4308-11. doi: 10.1128/AAC.00234-15. Epub 2015 Apr 20.


Influence of the preparation method on the physicochemical properties of indomethacin and methyl-β-cyclodextrin complexes.

Rudrangi SR, Bhomia R, Trivedi V, Vine GJ, Mitchell JC, Alexander BD, Wicks SR.

Int J Pharm. 2015 Feb 20;479(2):381-90. doi: 10.1016/j.ijpharm.2015.01.010. Epub 2015 Jan 8.


Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species.

Lamoth F, Alexander BD, Juvvadi PR, Steinbach WJ.

J Antimicrob Chemother. 2015 May;70(5):1408-11. doi: 10.1093/jac/dku549. Epub 2015 Jan 3.


Reply to "Insufficient demonstration of long-term stability of Aspergillus galactomannan".

Wheat LJ, Nguyen MH, Alexander BD, Denning D, Caliendo AM, Lyon GM, Baden LR, Marty FM, Clancy C, Kirsch E, Noth P, Witt J, Sugrue M, Wingard JR.

J Clin Microbiol. 2014 Nov;52(11):4119. doi: 10.1128/JCM.02433-14. No abstract available.


Predictors of immune reconstitution syndrome in organ transplant recipients with cryptococcosis: implications for the management of immunosuppression.

Sun HY, Alexander BD, Huprikar S, Forrest GN, Bruno D, Lyon GM, Wray D, Johnson LB, Sifri CD, Razonable RR, Morris MI, Stosor V, Wagener MM, Singh N.

Clin Infect Dis. 2015 Jan 1;60(1):36-44. doi: 10.1093/cid/ciu711. Epub 2014 Sep 9. Erratum in: Clin Infect Dis. 2016 Jun 15;62(12):1621.


Hepatitis B core antibody-positive donors in cardiac transplantation: a single-center experience.

Horan JL, Stout JE, Alexander BD.

Transpl Infect Dis. 2014 Oct;16(5):859-63. doi: 10.1111/tid.12280. Epub 2014 Aug 25.


Nonmolecular methods for the diagnosis of respiratory fungal infections.

Lamoth F, Alexander BD.

Clin Lab Med. 2014 Jun;34(2):315-36. doi: 10.1016/j.cll.2014.02.006. Epub 2014 Apr 12. Review.


Epidemiology of invasive mold infections in lung transplant recipients.

Doligalski CT, Benedict K, Cleveland AA, Park B, Derado G, Pappas PG, Baddley JW, Zaas DW, Harris MT, Alexander BD.

Am J Transplant. 2014 Jun;14(6):1328-33. doi: 10.1111/ajt.12691. Epub 2014 Apr 11.


Long-term stability at -20 °C of Aspergillus galactomannan in serum and bronchoalveolar lavage specimens.

Wheat LJ, Nguyen MH, Alexander BD, Denning D, Caliendo AM, Lyon GM, Baden LR, Marty FM, Clancy C, Kirsch E, Noth P, Witt J, Sugrue M, Wingard JR.

J Clin Microbiol. 2014 Jun;52(6):2108-11. doi: 10.1128/JCM.03500-13. Epub 2014 Apr 9.


Role of autophagy genetic variants for the risk of Candida infections.

Rosentul DC, Plantinga TS, Farcas M, Oosting M, Hamza OJ, Scott WK, Alexander BD, Yang JC, Laird GM, Joosten LA, van der Meer JW, Perfect JR, Kullberg BJ, van der Ven AJ, Johnson MD, Netea MG.

Med Mycol. 2014 May;52(4):333-41. doi: 10.1093/mmy/myt035. Epub 2014 Apr 8.


Complexities associated with the molecular and proteomic identification of Paecilomyces species in the clinical mycology laboratory.

Barker AP, Horan JL, Slechta ES, Alexander BD, Hanson KE.

Med Mycol. 2014 Jul;52(5):537-45. doi: 10.1093/mmy/myu001. Epub 2014 Mar 30.


Endemic fungal infections in solid organ and hematopoietic cell transplant recipients enrolled in the Transplant-Associated Infection Surveillance Network (TRANSNET).

Kauffman CA, Freifeld AG, Andes DR, Baddley JW, Herwaldt L, Walker RC, Alexander BD, Anaissie EJ, Benedict K, Ito JI, Knapp KM, Lyon GM, Marr KA, Morrison VA, Park BJ, Patterson TF, Schuster MG, Chiller TM, Pappas PG.

Transpl Infect Dis. 2014 Apr;16(2):213-24. doi: 10.1111/tid.12186. Epub 2014 Mar 4.


CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.

Lionakis MS, Swamydas M, Fischer BG, Plantinga TS, Johnson MD, Jaeger M, Green NM, Masedunskas A, Weigert R, Mikelis C, Wan W, Lee CC, Lim JK, Rivollier A, Yang JC, Laird GM, Wheeler RT, Alexander BD, Perfect JR, Gao JL, Kullberg BJ, Netea MG, Murphy PM.

J Clin Invest. 2013 Dec;123(12):5035-51. doi: 10.1172/JCI71307. Epub 2013 Nov 1.


Development and evaluation of a calibrator material for nucleic acid-based assays for diagnosing aspergillosis.

Lyon GM, Abdul-Ali D, Loeffler J, White PL, Wickes B, Herrera ML, Alexander BD, Baden LR, Clancy C, Denning D, Nguyen MH, Sugrue M, Wheat LJ, Wingard JR, Donnelly JP, Barnes R, Patterson TF, Caliendo AM; AsTeC, IAAM, EAPCRI Investigators.

J Clin Microbiol. 2013 Jul;51(7):2403-5. doi: 10.1128/JCM.00744-13. Epub 2013 Apr 24.

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