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Items: 1 to 50 of 194

1.

The Effect of Zoledronic Acid on Serum Biomarkers among Patients with Chronic Low Back Pain and Modic Changes in Lumbar Magnetic Resonance Imaging.

Koivisto K, Karppinen J, Haapea M, Järvinen J, Kyllönen E, Tervonen O, Niinimäki J, Alini M, Lotz J, Dudli S, Samartzis D, Risteli J, Majuri ML, Alenius H, Grad S.

Diagnostics (Basel). 2019 Dec 4;9(4). pii: E212. doi: 10.3390/diagnostics9040212.

2.

Nanosized silver, but not titanium dioxide or zinc oxide, enhances oxidative stress and inflammatory response by inducing 5-HETE activation in THP-1 cells.

Poon WL, Lee JC, Leung KS, Alenius H, El-Nezami H, Karisola P.

Nanotoxicology. 2019 Nov 27:1-15. doi: 10.1080/17435390.2019.1687776. [Epub ahead of print]

PMID:
31775543
3.

Microbe-host interplay in atopic dermatitis and psoriasis.

Fyhrquist N, Muirhead G, Prast-Nielsen S, Jeanmougin M, Olah P, Skoog T, Jules-Clement G, Feld M, Barrientos-Somarribas M, Sinkko H, van den Bogaard EH, Zeeuwen PLJM, Rikken G, Schalkwijk J, Niehues H, Däubener W, Eller SK, Alexander H, Pennino D, Suomela S, Tessas I, Lybeck E, Baran AM, Darban H, Gangwar RS, Gerstel U, Jahn K, Karisola P, Yan L, Hansmann B, Katayama S, Meller S, Bylesjö M, Hupé P, Levi-Schaffer F, Greco D, Ranki A, Schröder JM, Barker J, Kere J, Tsoka S, Lauerma A, Soumelis V, Nestle FO, Homey B, Andersson B, Alenius H.

Nat Commun. 2019 Oct 16;10(1):4703. doi: 10.1038/s41467-019-12253-y.

4.

Epigenetic clocks and allostatic load reveal potential sex-specific drivers of biological ageing.

McCrory C, Fiorito G, McLoughlin S, Polidoro S, Ni Cheallaigh C, Bourke N, Karisola P, Alenius H, Vineis P, Layte R, Kenny RA.

J Gerontol A Biol Sci Med Sci. 2019 Oct 11. pii: glz241. doi: 10.1093/gerona/glz241. [Epub ahead of print]

PMID:
31603985
5.

Silver, titanium dioxide, and zinc oxide nanoparticles trigger miRNA/isomiR expression changes in THP-1 cells that are proportional to their health hazard potential.

Ndika J, Seemab U, Poon WL, Fortino V, El-Nezami H, Karisola P, Alenius H.

Nanotoxicology. 2019 Dec;13(10):1380-1395. doi: 10.1080/17435390.2019.1661040. Epub 2019 Sep 13.

PMID:
31519129
6.

Surface PEGylation suppresses pulmonary effects of CuO in allergen-induced lung inflammation.

Ilves M, Kinaret PAS, Ndika J, Karisola P, Marwah V, Fortino V, Fedutik Y, Correia M, Ehrlich N, Loeschner K, Besinis A, Vassallo J, Handy RD, Wolff H, Savolainen K, Greco D, Alenius H.

Part Fibre Toxicol. 2019 Jul 5;16(1):28. doi: 10.1186/s12989-019-0309-1.

7.

Molecular Signature of Asthma-Enhanced Sensitivity to CuO Nanoparticle Aerosols from 3D Cell Model.

Kooter I, Ilves M, Gröllers-Mulderij M, Duistermaat E, Tromp PC, Kuper F, Kinaret P, Savolainen K, Greco D, Karisola P, Ndika J, Alenius H.

ACS Nano. 2019 Jun 25;13(6):6932-6946. doi: 10.1021/acsnano.9b01823. Epub 2019 Jun 17.

8.

How does socio-economic position (SEP) get biologically embedded? A comparison of allostatic load and the epigenetic clock(s).

McCrory C, Fiorito G, Ni Cheallaigh C, Polidoro S, Karisola P, Alenius H, Layte R, Seeman T, Vineis P, Kenny RA.

Psychoneuroendocrinology. 2019 Jun;104:64-73. doi: 10.1016/j.psyneuen.2019.02.018. Epub 2019 Feb 16.

PMID:
30818253
9.

eUTOPIA: solUTion for Omics data PreprocessIng and Analysis.

Marwah VS, Scala G, Kinaret PAS, Serra A, Alenius H, Fortino V, Greco D.

Source Code Biol Med. 2019 Jan 29;14:1. doi: 10.1186/s13029-019-0071-7. eCollection 2019.

10.

CD300a expression is modulated in atopic dermatitis and could influence the inflammatory response.

Karra L, Gangwar RS, Puzzovio PG, Fyhrquist N, Minai-Fleminger Y, Landolina N, Simon HU, Alenius H, Leibovici V, Simon D, Levi-Schaffer F.

Allergy. 2019 Jul;74(7):1377-1380. doi: 10.1111/all.13724. Epub 2019 Feb 19. No abstract available.

PMID:
30667087
11.

Pulmonary effects of nanofibrillated celluloses in mice suggest that carboxylation lowers the inflammatory and acute phase responses.

Hadrup N, Knudsen KB, Berthing T, Wolff H, Bengtson S, Kofoed C, Espersen R, Højgaard C, Winther JR, Willemoës M, Wedin I, Nuopponen M, Alenius H, Norppa H, Wallin H, Vogel U.

Environ Toxicol Pharmacol. 2019 Feb;66:116-125. doi: 10.1016/j.etap.2019.01.003. Epub 2019 Jan 14.

PMID:
30665014
12.

Ultraviolet B radiation modifies circadian time in epidermal skin and in subcutaneous adipose tissue.

Nikkola V, Miettinen ME, Karisola P, Grönroos M, Ylianttila L, Alenius H, Snellman E, Partonen T.

Photodermatol Photoimmunol Photomed. 2019 May;35(3):157-163. doi: 10.1111/phpp.12440. Epub 2018 Dec 10.

PMID:
30472764
13.

Tape-stripping alters the microbe-host correlations in mouse skin.

Karisola P, Suomalainen A, Fortino V, Ottman N, Vendelin J, Wolff HJ, Ruokolainen L, Greco D, Fyhrquist N, Alenius H.

Allergy. 2019 Mar;74(3):617-621. doi: 10.1111/all.13653. Epub 2018 Nov 22. No abstract available.

PMID:
30372529
14.

Soil exposure modifies the gut microbiota and supports immune tolerance in a mouse model.

Ottman N, Ruokolainen L, Suomalainen A, Sinkko H, Karisola P, Lehtimäki J, Lehto M, Hanski I, Alenius H, Fyhrquist N.

J Allergy Clin Immunol. 2019 Mar;143(3):1198-1206.e12. doi: 10.1016/j.jaci.2018.06.024. Epub 2018 Aug 7.

PMID:
30097187
15.

Advanced tools for the safety assessment of nanomaterials.

Fadeel B, Farcal L, Hardy B, Vázquez-Campos S, Hristozov D, Marcomini A, Lynch I, Valsami-Jones E, Alenius H, Savolainen K.

Nat Nanotechnol. 2018 Jul;13(7):537-543. doi: 10.1038/s41565-018-0185-0. Epub 2018 Jul 6. Review.

PMID:
29980781
16.

Nanofibrillated cellulose causes acute pulmonary inflammation that subsides within a month.

Ilves M, Vilske S, Aimonen K, Lindberg HK, Pesonen S, Wedin I, Nuopponen M, Vanhala E, Højgaard C, Winther JR, Willemoës M, Vogel U, Wolff H, Norppa H, Savolainen K, Alenius H.

Nanotoxicology. 2018 Sep;12(7):729-746. doi: 10.1080/17435390.2018.1472312. Epub 2018 May 30.

PMID:
29848128
17.

Nasal mucosa and blood cell transcriptome profiles do not reflect respiratory symptoms associated with moisture damage.

Ndika J, Suojalehto H, Täubel M, Lehto M, Karvala K, Pallasaho P, Sund J, Auvinen P, Järvi K, Pekkanen J, Kinaret P, Greco D, Hyvärinen A, Alenius H.

Indoor Air. 2018 May 4. doi: 10.1111/ina.12472. [Epub ahead of print]

PMID:
29729044
18.

Elucidating differential nano-bio interactions of multi-walled andsingle-walled carbon nanotubes using subcellular proteomics.

Ndika JDT, Sund J, Alenius H, Puustinen A.

Nanotoxicology. 2018 Aug;12(6):554-570. doi: 10.1080/17435390.2018.1465141. Epub 2018 Apr 24.

PMID:
29688820
19.

DNA methylation in childhood asthma: an epigenome-wide meta-analysis.

Xu CJ, Söderhäll C, Bustamante M, Baïz N, Gruzieva O, Gehring U, Mason D, Chatzi L, Basterrechea M, Llop S, Torrent M, Forastiere F, Fantini MP, Carlsen KCL, Haahtela T, Morin A, Kerkhof M, Merid SK, van Rijkom B, Jankipersadsing SA, Bonder MJ, Ballereau S, Vermeulen CJ, Aguirre-Gamboa R, de Jongste JC, Smit HA, Kumar A, Pershagen G, Guerra S, Garcia-Aymerich J, Greco D, Reinius L, McEachan RRC, Azad R, Hovland V, Mowinckel P, Alenius H, Fyhrquist N, Lemonnier N, Pellet J, Auffray C; BIOS Consortium, van der Vlies P, van Diemen CC, Li Y, Wijmenga C, Netea MG, Moffatt MF, Cookson WOCM, Anto JM, Bousquet J, Laatikainen T, Laprise C, Carlsen KH, Gori D, Porta D, Iñiguez C, Bilbao JR, Kogevinas M, Wright J, Brunekreef B, Kere J, Nawijn MC, Annesi-Maesano I, Sunyer J, Melén E, Koppelman GH.

Lancet Respir Med. 2018 May;6(5):379-388. doi: 10.1016/S2213-2600(18)30052-3. Epub 2018 Feb 26.

20.

A novel glycocluster molecule prevents timothy-induced allergic airway inflammation in mice.

Lehto M, Wolff H, Leino R, Alenius H, Savolainen J.

Allergy. 2018 Aug;73(8):1700-1706. doi: 10.1111/all.13419. Epub 2018 Feb 13.

PMID:
29377154
21.

Nano-sized zinc oxide and silver, but not titanium dioxide, induce innate and adaptive immunity and antiviral response in differentiated THP-1 cells.

Poon WL, Alenius H, Ndika J, Fortino V, Kolhinen V, Meščeriakovas A, Wang M, Greco D, Lähde A, Jokiniemi J, Lee JC, El-Nezami H, Karisola P.

Nanotoxicology. 2017 Sep;11(7):936-951. doi: 10.1080/17435390.2017.1382600. Epub 2017 Sep 29.

PMID:
28958187
22.

Epithelial proteome profiling suggests the essential role of interferon-inducible proteins in patients with allergic rhinitis.

Ndika J, Airaksinen L, Suojalehto H, Karisola P, Fyhrquist N, Puustinen A, Alenius H.

J Allergy Clin Immunol. 2017 Nov;140(5):1288-1298. doi: 10.1016/j.jaci.2017.05.040. Epub 2017 Jun 19.

PMID:
28633877
23.

Network Analysis Reveals Similar Transcriptomic Responses to Intrinsic Properties of Carbon Nanomaterials in Vitro and in Vivo.

Kinaret P, Marwah V, Fortino V, Ilves M, Wolff H, Ruokolainen L, Auvinen P, Savolainen K, Alenius H, Greco D.

ACS Nano. 2017 Apr 25;11(4):3786-3796. doi: 10.1021/acsnano.6b08650. Epub 2017 Apr 11.

PMID:
28380293
24.

Significant disparities in allergy prevalence and microbiota between the young people in Finnish and Russian Karelia.

Ruokolainen L, Paalanen L, Karkman A, Laatikainen T, von Hertzen L, Vlasoff T, Markelova O, Masyuk V, Auvinen P, Paulin L, Alenius H, Fyhrquist N, Hanski I, Mäkelä MJ, Zilber E, Jousilahti P, Vartiainen E, Haahtela T.

Clin Exp Allergy. 2017 May;47(5):665-674. doi: 10.1111/cea.12895. Epub 2017 Mar 6.

PMID:
28165640
25.

Inhalation and Oropharyngeal Aspiration Exposure to Rod-Like Carbon Nanotubes Induce Similar Airway Inflammation and Biological Responses in Mouse Lungs.

Kinaret P, Ilves M, Fortino V, Rydman E, Karisola P, Lähde A, Koivisto J, Jokiniemi J, Wolff H, Savolainen K, Greco D, Alenius H.

ACS Nano. 2017 Jan 24;11(1):291-303. doi: 10.1021/acsnano.6b05652. Epub 2017 Jan 11.

PMID:
28045493
26.

Characterization of sputum biomarkers for asthma-COPD overlap syndrome.

Gao J, Iwamoto H, Koskela J, Alenius H, Hattori N, Kohno N, Laitinen T, Mazur W, Pulkkinen V.

Int J Chron Obstruct Pulmon Dis. 2016 Sep 30;11:2457-2465. eCollection 2016. Erratum in: Int J Chron Obstruct Pulmon Dis. 2017 Apr 18;12 :1191.

27.

Genotoxic and inflammatory effects of nanofibrillated cellulose in murine lungs.

Catalán J, Rydman E, Aimonen K, Hannukainen KS, Suhonen S, Vanhala E, Moreno C, Meyer V, Perez DD, Sneck A, Forsström U, Højgaard C, Willemoes M, Winther JR, Vogel U, Wolff H, Alenius H, Savolainen KM, Norppa H.

Mutagenesis. 2017 Jan;32(1):23-31. doi: 10.1093/mutage/gew035. Epub 2016 Jul 28.

PMID:
27470699
28.

[Pregnancy contraception (Current Care Guideline)].

Halttunen-Nieminen M, Piltonen T, Alenius H, Apukka L, Kosunen E, Pietilä K, Sihvo S, Vuorela P, Väänänen E, Yli-Kivistö T.

Duodecim. 2016;132(10):932-3. Finnish.

PMID:
27382829
29.

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses.

Aho V, Ollila HM, Kronholm E, Bondia-Pons I, Soininen P, Kangas AJ, Hilvo M, Seppälä I, Kettunen J, Oikonen M, Raitoharju E, Hyötyläinen T, Kähönen M, Viikari JS, Härmä M, Sallinen M, Olkkonen VM, Alenius H, Jauhiainen M, Paunio T, Lehtimäki T, Salomaa V, Orešič M, Raitakari OT, Ala-Korpela M, Porkka-Heiskanen T.

Sci Rep. 2016 Apr 22;6:24828. doi: 10.1038/srep24828.

30.

Isotretinoin treatment reduces acne lesions but not directly lesional acne inflammation.

Kelhälä HL, Fyhrquist N, Palatsi R, Lehtimäki S, Väyrynen JP, Kubin ME, Kallioinen M, Alenius H, Tasanen K, Lauerma A.

Exp Dermatol. 2016 Jun;25(6):477-8. doi: 10.1111/exd.12971. Epub 2016 Mar 2. No abstract available.

PMID:
26845242
31.

Innate and adaptive immunity in the development of depression: An update on current knowledge and technological advances.

Haapakoski R, Ebmeier KP, Alenius H, Kivimäki M.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Apr 3;66:63-72. doi: 10.1016/j.pnpbp.2015.11.012. Epub 2015 Nov 26. Review.

32.

A novel mannoside-glycocluster adjuvant: Compared in vitro to CpG ODN and MPL and tested in vivo in mouse asthma model.

Mäkinen K, Mukherjee C, Leino M, Panchadhayee R, Lehto M, Wolff H, Alenius H, Leino R, Savolainen J.

Allergol Immunopathol (Madr). 2016 Jan-Feb;44(1):9-17. doi: 10.1016/j.aller.2015.04.008. Epub 2015 Sep 26.

PMID:
26395525
33.

[Current Care Guideline: Eating disorders].

Suokas J, Alenius H, Ebeling H, Haapasalo-Pesu KM, Järvi L, Koskinen M, Laukkanen E, Meskanen K, Morin-Papunen L, Ryöppönen A, Salonen U, Tossavainen P, Vuorela P; Päivitystiivistelmä.

Duodecim. 2015;131(12):1200-1. Finnish.

PMID:
26245050
34.

Visualization of Nanofibrillar Cellulose in Biological Tissues Using a Biotinylated Carbohydrate Binding Module of β-1,4-Glycanase.

Knudsen KB, Kofoed C, Espersen R, Højgaard C, Winther JR, Willemoës M, Wedin I, Nuopponen M, Vilske S, Aimonen K, Weydahl IE, Alenius H, Norppa H, Wolff H, Wallin H, Vogel U.

Chem Res Toxicol. 2015 Aug 17;28(8):1627-35. doi: 10.1021/acs.chemrestox.5b00271. Epub 2015 Aug 6.

PMID:
26208679
35.

Negligible respiratory irritation and inflammation potency of pigmentary TiO2 in mice.

Leppänen M, Korpi A, Yli-Pirilä P, Lehto M, Wolff H, Kosma VM, Alenius H, Pasanen P.

Inhal Toxicol. 2015;27(8):378-86. doi: 10.3109/08958378.2015.1056890. Epub 2015 Jul 15.

PMID:
26176585
36.

Invariant Natural Killer T Cells Play a Role in Chemotaxis, Complement Activation and Mucus Production in a Mouse Model of Airway Hyperreactivity and Inflammation.

Karisola P, Lehto M, Kinaret P, Ahonen N, Haapakoski R, Anthoni M, Taniguchi M, Wolff H, Puustinen A, Alenius H.

PLoS One. 2015 Jun 12;10(6):e0129446. doi: 10.1371/journal.pone.0129446. eCollection 2015.

37.

Cumulative meta-analysis of interleukins 6 and 1β, tumour necrosis factor α and C-reactive protein in patients with major depressive disorder.

Haapakoski R, Mathieu J, Ebmeier KP, Alenius H, Kivimäki M.

Brain Behav Immun. 2015 Oct;49:206-15. doi: 10.1016/j.bbi.2015.06.001. Epub 2015 Jun 9.

38.

A Single Aspiration of Rod-like Carbon Nanotubes Induces Asbestos-like Pulmonary Inflammation Mediated in Part by the IL-1 Receptor.

Rydman EM, Ilves M, Vanhala E, Vippola M, Lehto M, Kinaret PA, Pylkkänen L, Happo M, Hirvonen MR, Greco D, Savolainen K, Wolff H, Alenius H.

Toxicol Sci. 2015 Sep;147(1):140-55. doi: 10.1093/toxsci/kfv112. Epub 2015 Jun 5.

PMID:
26048651
39.

Level of Fatty Acid Binding Protein 5 (FABP5) Is Increased in Sputum of Allergic Asthmatics and Links to Airway Remodeling and Inflammation.

Suojalehto H, Kinaret P, Kilpeläinen M, Toskala E, Ahonen N, Wolff H, Alenius H, Puustinen A.

PLoS One. 2015 May 28;10(5):e0127003. doi: 10.1371/journal.pone.0127003. eCollection 2015.

40.

Functional Beta2-Integrins Restrict Skin Inflammation In Vivo.

Savinko TS, Morrison VL, Uotila LM, Wolff CHJ, Alenius HT, Fagerholm SC.

J Invest Dermatol. 2015 Sep;135(9):2249-2257. doi: 10.1038/jid.2015.164. Epub 2015 Apr 28.

41.

Osteoclast activators are elevated in intervertebral disks with Modic changes among patients operated for herniated nucleus pulposus.

Torkki M, Majuri ML, Wolff H, Koskelainen T, Haapea M, Niinimäki J, Alenius H, Lotz J, Karppinen J.

Eur Spine J. 2016 Jan;25(1):207-16. doi: 10.1007/s00586-015-3897-y. Epub 2015 Mar 27.

PMID:
25813008
42.

Size-dependent ROS production by palladium and nickel nanoparticles in cellular and acellular environments - An indication for the catalytic nature of their interactions.

Neubauer N, Palomaeki J, Karisola P, Alenius H, Kasper G.

Nanotoxicology. 2015;9(8):1059-66. doi: 10.3109/17435390.2015.1019585. Epub 2015 Mar 20.

PMID:
25791496
43.

Hunt for the origin of allergy - comparing the Finnish and Russian Karelia.

Haahtela T, Laatikainen T, Alenius H, Auvinen P, Fyhrquist N, Hanski I, von Hertzen L, Jousilahti P, Kosunen TU, Markelova O, Mäkelä MJ, Pantelejev V, Uhanov M, Zilber E, Vartiainen E.

Clin Exp Allergy. 2015 May;45(5):891-901. doi: 10.1111/cea.12527.

PMID:
25772429
44.

Interleukin-6 as a predictor of symptom resolution in psychological distress: a cohort study.

Virtanen M, Shipley MJ, Batty GD, Hamer M, Allan CL, Lowe GD, Ebmeier KP, Akbaraly TN, Alenius H, Haapakoski R, Singh-Manoux A, Kivimäki M.

Psychol Med. 2015 Jul;45(10):2137-44. doi: 10.1017/S0033291715000070. Epub 2015 Feb 20.

PMID:
25697833
45.

BACA: bubble chArt to compare annotations.

Fortino V, Alenius H, Greco D.

BMC Bioinformatics. 2015 Feb 5;16:37. doi: 10.1186/s12859-015-0477-4.

46.

Co-exposure with fullerene may strengthen health effects of organic industrial chemicals.

Lehto M, Karilainen T, Róg T, Cramariuc O, Vanhala E, Tornaeus J, Taberman H, Jänis J, Alenius H, Vattulainen I, Laine O.

PLoS One. 2014 Dec 4;9(12):e114490. doi: 10.1371/journal.pone.0114490. eCollection 2014.

47.

A secretomics analysis reveals major differences in the macrophage responses towards different types of carbon nanotubes.

Palomäki J, Sund J, Vippola M, Kinaret P, Greco D, Savolainen K, Puustinen A, Alenius H.

Nanotoxicology. 2015;9(6):719-28. doi: 10.3109/17435390.2014.969346. Epub 2014 Oct 17.

PMID:
25325160
48.

Inhalation of rod-like carbon nanotubes causes unconventional allergic airway inflammation.

Rydman EM, Ilves M, Koivisto AJ, Kinaret PA, Fortino V, Savinko TS, Lehto MT, Pulkkinen V, Vippola M, Hämeri KJ, Matikainen S, Wolff H, Savolainen KM, Greco D, Alenius H.

Part Fibre Toxicol. 2014 Oct 16;11:48. doi: 10.1186/s12989-014-0048-2.

49.

Acinetobacter species in the skin microbiota protect against allergic sensitization and inflammation.

Fyhrquist N, Ruokolainen L, Suomalainen A, Lehtimäki S, Veckman V, Vendelin J, Karisola P, Lehto M, Savinko T, Jarva H, Kosunen TU, Corander J, Auvinen P, Paulin L, von Hertzen L, Laatikainen T, Mäkelä M, Haahtela T, Greco D, Hanski I, Alenius H.

J Allergy Clin Immunol. 2014 Dec;134(6):1301-1309.e11. doi: 10.1016/j.jaci.2014.07.059. Epub 2014 Sep 26.

PMID:
25262465
50.

Genotoxic and immunotoxic effects of cellulose nanocrystals in vitro.

Catalán J, Ilves M, Järventaus H, Hannukainen KS, Kontturi E, Vanhala E, Alenius H, Savolainen KM, Norppa H.

Environ Mol Mutagen. 2015 Mar;56(2):171-82. doi: 10.1002/em.21913. Epub 2014 Sep 24.

PMID:
25257801

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