Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 17

1.

Small molecule inhibitors of LcrF, a Yersinia pseudotuberculosis transcription factor, attenuate virulence and limit infection in a murine pneumonia model.

Garrity-Ryan LK, Kim OK, Balada-Llasat JM, Bartlett VJ, Verma AK, Fisher ML, Castillo C, Songsungthong W, Tanaka SK, Levy SB, Mecsas J, Alekshun MN.

Infect Immun. 2010 Nov;78(11):4683-90. doi: 10.1128/IAI.01305-09. Epub 2010 Sep 7.

2.

N-Hydroxybenzimidazole inhibitors of ExsA MAR transcription factor in Pseudomonas aeruginosa: In vitro anti-virulence activity and metabolic stability.

Grier MC, Garrity-Ryan LK, Bartlett VJ, Klausner KA, Donovan PJ, Dudley C, Alekshun MN, Tanaka SK, Draper MP, Levy SB, Kim OK.

Bioorg Med Chem Lett. 2010 Jun 1;20(11):3380-3. doi: 10.1016/j.bmcl.2010.04.014. Epub 2010 Apr 11.

PMID:
20434913
3.

N-hydroxybenzimidazole inhibitors of the transcription factor LcrF in Yersinia: novel antivirulence agents.

Kim OK, Garrity-Ryan LK, Bartlett VJ, Grier MC, Verma AK, Medjanis G, Donatelli JE, Macone AB, Tanaka SK, Levy SB, Alekshun MN.

J Med Chem. 2009 Sep 24;52(18):5626-34. doi: 10.1021/jm9006577.

4.

Novel anti-infection agents: small-molecule inhibitors of bacterial transcription factors.

Bowser TE, Bartlett VJ, Grier MC, Verma AK, Warchol T, Levy SB, Alekshun MN.

Bioorg Med Chem Lett. 2007 Oct 15;17(20):5652-5. Epub 2007 Aug 21.

PMID:
17766109
5.

Molecular mechanisms of antibacterial multidrug resistance.

Alekshun MN, Levy SB.

Cell. 2007 Mar 23;128(6):1037-50. Review.

6.

MarA, SoxS and Rob function as virulence factors in an Escherichia coli murine model of ascending pyelonephritis.

Casaz P, Garrity-Ryan LK, McKenney D, Jackson C, Levy SB, Tanaka SK, Alekshun MN.

Microbiology. 2006 Dec;152(Pt 12):3643-50.

PMID:
17159217
7.

Commensals upon us.

Alekshun MN, Levy SB.

Biochem Pharmacol. 2006 Mar 30;71(7):893-900. Epub 2006 Feb 7. Review.

PMID:
16464437
8.

New advances in antibiotic development and discovery.

Alekshun MN.

Expert Opin Investig Drugs. 2005 Feb;14(2):117-34. Review.

PMID:
15757391
10.

Beyond comparison--antibiotics from genome data?

Alekshun MN.

Nat Biotechnol. 2001 Dec;19(12):1124-5. No abstract available.

PMID:
11731779
11.

The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution.

Alekshun MN, Levy SB, Mealy TR, Seaton BA, Head JF.

Nat Struct Biol. 2001 Aug;8(8):710-4.

PMID:
11473263
13.

The mar regulon: multiple resistance to antibiotics and other toxic chemicals.

Alekshun MN, Levy SB.

Trends Microbiol. 1999 Oct;7(10):410-3. Review.

PMID:
10498949
15.

Characterization of MarR superrepressor mutants.

Alekshun MN, Levy SB.

J Bacteriol. 1999 May;181(10):3303-6.

16.

Multidrug resistance following expression of the Escherichia coli marA gene in Mycobacterium smegmatis.

McDermott PF, White DG, Podglajen I, Alekshun MN, Levy SB.

J Bacteriol. 1998 Jun;180(11):2995-8.

17.

Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon.

Alekshun MN, Levy SB.

Antimicrob Agents Chemother. 1997 Oct;41(10):2067-75. Review. No abstract available.

Supplemental Content

Loading ...
Support Center