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Items: 11

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1.

Hexokinase 2 Is an Intracellular Glucose Sensor of Yeast Cells That Maintains the Structure and Activity of Mig1 Protein Repressor Complex.

Vega M, Riera A, Fernández-Cid A, Herrero P, Moreno F.

J Biol Chem. 2016 Apr 1;291(14):7267-85. doi: 10.1074/jbc.M115.711408. Epub 2016 Feb 10.

2.

A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase.

Herrera MC, Tognetti S, Riera A, Zech J, Clarke P, Fernández-Cid A, Speck C.

Nucleic Acids Res. 2015 Dec 2;43(21):10238-50. doi: 10.1093/nar/gkv881. Epub 2015 Sep 3.

3.

Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function.

Sun J, Fernandez-Cid A, Riera A, Tognetti S, Yuan Z, Stillman B, Speck C, Li H.

Genes Dev. 2014 Oct 15;28(20):2291-303. doi: 10.1101/gad.242313.114.

4.

A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA.

Samel SA, Fernández-Cid A, Sun J, Riera A, Tognetti S, Herrera MC, Li H, Speck C.

Genes Dev. 2014 Aug 1;28(15):1653-66. doi: 10.1101/gad.242404.114.

5.

The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation.

Evrin C, Fernández-Cid A, Riera A, Zech J, Clarke P, Herrera MC, Tognetti S, Lurz R, Speck C.

Nucleic Acids Res. 2014 Feb;42(4):2257-69. doi: 10.1093/nar/gkt1148. Epub 2013 Nov 14.

6.

Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.

Sun J, Evrin C, Samel SA, Fernández-Cid A, Riera A, Kawakami H, Stillman B, Speck C, Li H.

Nat Struct Mol Biol. 2013 Aug;20(8):944-51. doi: 10.1038/nsmb.2629. Epub 2013 Jul 14.

7.

The ORC/Cdc6/MCM2–7 complex, a new power player for regulated helicase loading.

Riera A, Fernández-Cid A, Speck C.

Cell Cycle. 2013 Jul 15;12(14):2155-6. No abstract available.

8.

An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly.

Fernández-Cid A, Riera A, Tognetti S, Herrera MC, Samel S, Evrin C, Winkler C, Gardenal E, Uhle S, Speck C.

Mol Cell. 2013 May 23;50(4):577-88. doi: 10.1016/j.molcel.2013.03.026. Epub 2013 Apr 18.

9.

In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.

Evrin C, Fernández-Cid A, Zech J, Herrera MC, Riera A, Clarke P, Brill S, Lurz R, Speck C.

Nucleic Acids Res. 2013 Mar 1;41(5):3162-72. doi: 10.1093/nar/gkt043. Epub 2013 Feb 1.

10.

Yeast importin-β is required for nuclear import of the Mig2 repressor.

Fernández-Cid A, Vega M, Herrero P, Moreno F.

BMC Cell Biol. 2012 Nov 6;13:31. doi: 10.1186/1471-2121-13-31.

11.

Glucose levels regulate the nucleo-mitochondrial distribution of Mig2.

Fernández-Cid A, Riera A, Herrero P, Moreno F.

Mitochondrion. 2012 May;12(3):370-80. doi: 10.1016/j.mito.2012.02.001. Epub 2012 Feb 12.

PMID:
22353369

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