Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 36

1.

Synthesis and Evaluation of Folate-Conjugated Phenanthraquinones for Tumor-Targeted Oxidative Chemotherapy.

Kumar A, Chelvam V, Sakkarapalayam M, Li G, Sanchez-Cruz P, Piñero NS, Low PS, Alegria AE.

Open J Med Chem. 2016 Mar;6(1):1-17. Epub 2016 Mar 11.

2.

Identification of the first inhibitor of the GBP1:PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells.

Andreoli M, Persico M, Kumar A, Orteca N, Kumar V, Pepe A, Mahalingam S, Alegria AE, Petrella L, Sevciunaite L, Camperchioli A, Mariani M, Di Dato A, Novellino E, Scambia G, Malhotra SV, Ferlini C, Fattorusso C.

J Med Chem. 2014 Oct 9;57(19):7916-32. doi: 10.1021/jm5009902. Epub 2014 Sep 26.

3.

Metal-independent reduction of hydrogen peroxide by semiquinones.

Sanchez-Cruz P, Santos A, Diaz S, Alegría AE.

Chem Res Toxicol. 2014 Aug 18;27(8):1380-6. doi: 10.1021/tx500089x. Epub 2014 Jul 29.

4.

Roles of hydrophilicities and hydrophobicities of dye and sacrificial electron donor on the photochemical pathway.

Sanchez-Cruz P, Dejesus-Andino F, Alegria AE.

J Photochem Photobiol A Chem. 2012 May 15;236:54-60. Epub 2012 Mar 29.

5.

Synthetic and application perspectives of azapodophyllotoxins: alternative scaffolds of podophyllotoxin.

Kumar A, Kumar V, Alegria AE, Malhotra SV.

Curr Med Chem. 2011;18(25):3853-70. Review.

6.

N-hydroxyethyl-4-aza-didehydropodophyllotoxin derivatives as potential antitumor agents.

Kumar A, Kumar V, Alegria AE, Malhotra SV.

Eur J Pharm Sci. 2011 Sep 18;44(1-2):21-6. doi: 10.1016/j.ejps.2011.04.013. Epub 2011 May 13.

7.
8.

Quenching enhancement of the singlet excited state of pheophorbide-a by DNA in the presence of the quinone carboquone.

Díaz-Espinosa Y, Crespo-Hernández CE, Alegría AE, García C, Arce R.

Photochem Photobiol. 2011 Mar-Apr;87(2):275-83. doi: 10.1111/j.1751-1097.2010.00869.x. Epub 2011 Jan 4.

9.

Role of quinones in the ascorbate reduction rates of S-nitrosoglutathione.

Sanchez-Cruz P, Garcia C, Alegria AE.

Free Radic Biol Med. 2010 Nov 15;49(9):1387-94. doi: 10.1016/j.freeradbiomed.2010.07.022. Epub 2010 Aug 5.

10.

Quinone-enhanced reduction of nitric oxide by xanthine/xanthine oxidase.

Sanchez-Cruz P, Alegría AE.

Chem Res Toxicol. 2009 May;22(5):818-23. doi: 10.1021/tx800392j.

11.

Role of the nitro functionality in the DNA binding of 3-nitro-10-methylbenzothiazolo[3,2-a]quinolinium chloride.

Colón IG, González FA, Cordero M, Zayas B, Velez C, Cox O, Kumar A, Alegría AE.

Chem Res Toxicol. 2008 Sep;21(9):1706-15. doi: 10.1021/tx800076c. Epub 2008 Aug 30.

12.

Photosensitized oxidation of hypoxanthine and xanthine by aluminum phthalocyanine tetrasulfonate. Role of the alkylating quinone 2,5-dichloro-diaziridinyl-1,4-benzoquinone.

Alegria AE, Inostroza Y, Kumar A.

Photochem Photobiol. 2008 Nov-Dec;84(6):1583-8. doi: 10.1111/j.1751-1097.2008.00389.x. Epub 2008 Jun 20.

13.

Quinone-enhanced sonochemical production of nitric oxide from s-nitrosoglutathione.

Alegría AE, Dejesús-Andino FJ, Sanchez-Cruz P.

Ultrason Sonochem. 2009 Jan;16(1):190-6. doi: 10.1016/j.ultsonch.2008.05.009. Epub 2008 May 24.

14.

Thiols oxidation and covalent binding of BSA by cyclolignanic quinones are enhanced by the magnesium cation.

Alegria AE, Sanchez-Cruz P, Kumar A, Garcia C, Gonzalez FA, Orellano A, Zayas B, Gordaliza M.

Free Radic Res. 2008 Jan;42(1):70-81. doi: 10.1080/10715760701790671.

15.

Ortho-quinone-enhanced ascorbate oxidation. Combined roles of lipid charge and the magnesium cation.

Alegría AE, Sanchez-Cruz P.

Toxicol Environ Chem. 2008 Mar 1;90(2):327-340.

16.

Comparison of the nucleic acid covalent binding capacity of two nitro-substituted benzazolo[3,2-a]quinolinium salts upon enzymatic reduction.

Zayas B, Beyley J, Terron M, Cordero M, Hernandez W, Alegría AE, Cox O.

Toxicol In Vitro. 2007 Sep;21(6):1155-64. Epub 2007 Mar 13.

17.

Sonochemically induced covalent binding of calf thymus DNA by aziridinylquinones.

Alegria AE, Sanchez-Cruz P, Lopez-Colon D.

Radiat Res. 2005 Oct;164(4 Pt 1):446-52.

PMID:
16187747
18.

Oxidation of tea extracts and tea catechins by molecular oxygen.

Roginsky V, Alegria AE.

J Agric Food Chem. 2005 Jun 1;53(11):4529-35.

PMID:
15913321
19.

Quinone-enhanced ascorbate reduction of nitric oxide: role of quinone redox potential.

Alegria AE, Sanchez S, Quintana I.

Free Radic Res. 2004 Oct;38(10):1107-12.

PMID:
15512799
20.

Alkaline-earth cations enhance ortho-quinone-catalyzed ascorbate oxidation.

Alegría AE, Sanchez-Cruz P, Rivas L.

Free Radic Biol Med. 2004 Nov 15;37(10):1631-9.

PMID:
15477014
21.
22.

Reductive activation and thiol reactivity of benzazolo[3,2-a]quinolinium salts.

Alegria AE, Flores W, Cordones E, Rivera L, Sanchez-Cruz P, Cordero M, Cox O.

Toxicology. 2004 Jul 1;199(2-3):87-96.

PMID:
15147783
23.

Reductive activation of terpenylnaphthoquinones.

Alegria AE, Cordones E, Santiago G, Marcano Y, Sanchez S, Gordaliza M, Martín-Martín ML.

Toxicology. 2002 Jun 14;175(1-3):167-75.

PMID:
12049845
24.
25.

Sonochemistry of quinones in argon-saturated aqueous solutions: enhanced cytochrome c reduction.

Lawson RC, Ferrer A, Flores W, Alegría AE.

Chem Res Toxicol. 1999 Sep;12(9):850-4.

PMID:
10490507
26.
27.

Adriamycin and daunomycin semiquinone membrane/buffer partition constants using the spin-broadening technique.

Alegría AE, Santiago G.

Arch Biochem Biophys. 1997 Oct 1;346(1):91-5.

PMID:
9328288
28.

Photochemistry of water-soluble quinones. Production of a water-derived spin adduct.

Alegría AE, Ferrer A, Sepúlveda E.

Photochem Photobiol. 1997 Oct;66(4):436-42.

PMID:
9337614
29.

Photophysical properties of gilvocarcins V and M and their binding constant to calf thymus DNA.

Oyola R, Arce R, Alegría AE, García C.

Photochem Photobiol. 1997 May;65(5):802-10.

PMID:
9155255
30.

A comparative study of the visible light photochemistry of gilvocarcins V and M.

Alegría AE, Zayas L, Guevara N.

Photochem Photobiol. 1995 Sep;62(3):409-15.

PMID:
8570700
31.

Reductive activation of benzazolo[3,2-a]-quinolinium chlorides.

Alegría AE, Cox O, Santiago V, Colón M, Reyes Z, Zayas L, Rivera LA, Dumas JA.

Free Radic Biol Med. 1993 Jul;15(1):49-56.

PMID:
8395453
32.

Semiquinones derived from anthraquinone-containing antitumor drugs can partition into phosphatidylcholine bilayers.

Alegría AE, Rodríguez MS, Hernández J.

Biochim Biophys Acta. 1990 Jul 20;1035(1):51-5.

PMID:
2166575
33.

Free radicals induced by adriamycin-sensitive and adriamycin-resistant cells: a spin-trapping study.

Alegria AE, Samuni A, Mitchell JB, Riesz P, Russo A.

Biochemistry. 1989 Oct 17;28(21):8653-8.

PMID:
2557905
34.

An ESR study of the visible light photochemistry of gilvocarcin V.

Alegria AE, Krishna CM, Elespuru RK, Riesz P.

Photochem Photobiol. 1989 Mar;49(3):257-65.

PMID:
2543995
35.

Photochemistry of aqueous solutions of benzazolo[3,2-a]quinolinium salts. A spin-trapping study using 17O-enriched water and oxygen.

Alegria AE, Cox O, Dumas JA, Rivera LA, Riesz P.

Biochim Biophys Acta. 1988 Oct 13;967(1):1-10.

PMID:
2844279
36.

Photochemistry of aqueous adriamycin and daunomycin. A spin trapping study with 17O enriched oxygen and water.

Alegria AE, Riesz P.

Photochem Photobiol. 1988 Aug;48(2):147-52. No abstract available.

PMID:
2851841

Supplemental Content

Loading ...
Support Center