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Items: 1 to 50 of 144

1.

Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.

Moreno-Grau S, de Rojas I, Hernández I, Quintela I, Montrreal L, Alegret M, Hernández-Olasagarre B, Madrid L, González-Perez A, Maroñas O, Rosende-Roca M, Mauleón A, Vargas L, Lafuente A, Abdelnour C, Rodríguez-Gómez O, Gil S, Santos-Santos MÁ, Espinosa A, Ortega G, Sanabria Á, Pérez-Cordón A, Cañabate P, Moreno M, Preckler S, Ruiz S, Aguilera N, Pineda JA, Macías J, Alarcón-Martín E, Sotolongo-Grau O; GR@ACE consortium; DEGESCO consortium; Alzheimer's Disease Neuroimaging Initiative, Marquié M, Monté-Rubio G, Valero S, Benaque A, Clarimón J, Bullido MJ, García-Ribas G, Pástor P, Sánchez-Juan P, Álvarez V, Piñol-Ripoll G, García-Alberca JM, Royo JL, Franco E, Mir P, Calero M, Medina M, Rábano A, Ávila J, Antúnez C, Real LM, Orellana A, Carracedo Á, Sáez ME, Tárraga L, Boada M, Ruiz A.

Alzheimers Dement. 2019 Aug 13. pii: S1552-5260(19)35117-9. doi: 10.1016/j.jalz.2019.06.4950. [Epub ahead of print]

2.

Letter Verbal Fluency in Spanish-, Basque-, and Catalan-Speaking Individuals: Does the Selection of the Letters Influence the Outcome?

Olabarrieta-Landa L, Benito-Sánchez I, Alegret M, Gailhajanet A, Landa Torre E, López-Mugartza JC, Arango-Lasprilla JC.

J Speech Lang Hear Res. 2019 Jul 15;62(7):2400-2410. doi: 10.1044/2019_JSLHR-L-18-0365. Epub 2019 Jun 19.

PMID:
31216206
3.

Visual impairment in aging and cognitive decline: experience in a Memory Clinic.

Marquié M, Castilla-Martí M, Valero S, Martínez J, Sánchez D, Hernández I, Rosende-Roca M, Vargas L, Mauleón A, Rodríguez-Gómez O, Abdelnour C, Gil S, Santos-Santos MA, Alegret M, Espinosa A, Ortega G, Pérez-Cordón A, Sanabria Á, Roberto N, Moreno-Grau S, de Rojas I, Simó R, Ciudin A, Hernández C, Orellana A, Monté-Rubio G, Benaque A, Ruiz A, Tárraga L, Boada M.

Sci Rep. 2019 Jun 18;9(1):8698. doi: 10.1038/s41598-019-45055-9.

4.

The MOPEAD project: Advancing patient engagement for the detection of "hidden" undiagnosed cases of Alzheimer's disease in the community.

Rodríguez-Gómez O, Rodrigo A, Iradier F, Santos-Santos MA, Hundemer H, Ciudin A, Sannemann L, Zwan M, Glaysher B, Wimo A, Bonn J, Johansson G, Rodriguez I, Alegret M, Gove D, Pinó S, Trigueros P, Kivipelto M, Mathews B, Ciudad A, Ferreira D, Bintener C, Gurruchaga M, Westman E, Belger M, Valero S, Maguire P, Krivec D, Kramberger M, Simó R, Garro IP, Visser PJ, Dumas A, Georges J, Jessen F, Winblad B, Shering C, Stewart N, Campo L, Boada M; MOPEAD Consortium.

Alzheimers Dement. 2019 Jun;15(6):828-839. doi: 10.1016/j.jalz.2019.02.003. Epub 2019 May 7. Review.

5.

mTOR is a Key Protein Involved in the Metabolic Effects of Simple Sugars.

Sangüesa G, Roglans N, Baena M, Velázquez AM, Laguna JC, Alegret M.

Int J Mol Sci. 2019 Mar 5;20(5). pii: E1117. doi: 10.3390/ijms20051117. Review.

6.

Correlations between plasma and PET beta-amyloid levels in individuals with subjective cognitive decline: the Fundació ACE Healthy Brain Initiative (FACEHBI).

de Rojas I, Romero J, Rodríguez-Gomez O, Pesini P, Sanabria A, Pérez-Cordon A, Abdelnour C, Hernández I, Rosende-Roca M, Mauleón A, Vargas L, Alegret M, Espinosa A, Ortega G, Gil S, Guitart M, Gailhajanet A, Santos-Santos MA, Moreno-Grau S, Sotolongo-Grau O, Ruiz S, Montrreal L, Martín E, Pelejà E, Lomeña F, Campos F, Vivas A, Gómez-Chiari M, Tejero MA, Giménez J, Pérez-Grijalba V, Marquié GM, Monté-Rubio G, Valero S, Orellana A, Tárraga L, Sarasa M, Ruiz A, Boada M; FACEHBI study.

Alzheimers Res Ther. 2018 Nov 29;10(1):119. doi: 10.1186/s13195-018-0444-1.

7.

Exploring Genetic Associations of Alzheimer's Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes.

Espinosa A, Hernández-Olasagarre B, Moreno-Grau S, Kleineidam L, Heilmann-Heimbach S, Hernández I, Wolfsgruber S, Wagner H, Rosende-Roca M, Mauleón A, Vargas L, Lafuente A, Rodríguez-Gómez O, Abdelnour C, Gil S, Marquié M, Santos-Santos MA, Sanabria Á, Ortega G, Monté-Rubio G, Pérez A, Ibarria M, Ruiz S, Kornhuber J, Peters O, Frölich L, Hüll M, Wiltfang J, Luck T, Riedel-Heller S, Montrreal L, Cañabate P, Moreno M, Preckler S, Aguilera N, de Rojas I, Orellana A, Alegret M, Valero S, Nöthen MM, Wagner M, Jessen F, Tárraga L, Boada M, Ramírez A, Ruiz A.

Front Aging Neurosci. 2018 Oct 30;10:340. doi: 10.3389/fnagi.2018.00340. eCollection 2018.

8.

Usefulness of peripapillary nerve fiber layer thickness assessed by optical coherence tomography as a biomarker for Alzheimer's disease.

Sánchez D, Castilla-Marti M, Rodríguez-Gómez O, Valero S, Piferrer A, Martínez G, Martínez J, Serra J, Moreno-Grau S, Hernández-Olasagarre B, De Rojas I, Hernández I, Abdelnour C, Rosende-Roca M, Vargas L, Mauleón A, Santos-Santos MA, Alegret M, Ortega G, Espinosa A, Pérez-Cordón A, Sanabria Á, Ciudin A, Simó R, Hernández C, Villaoslada P, Ruiz A, Tàrraga L, Boada M.

Sci Rep. 2018 Nov 5;8(1):16345. doi: 10.1038/s41598-018-34577-3.

9.

Risk of progression to Alzheimer's disease for different neuropsychological Mild Cognitive Impairment subtypes: A hierarchical meta-analysis of longitudinal studies.

Oltra-Cucarella J, Ferrer-Cascales R, Alegret M, Gasparini R, Díaz-Ortiz LM, Ríos R, Martínez-Nogueras ÁL, Onandia I, Pérez-Vicente JA, Cabello-Rodríguez L, Sánchez-SanSegundo M.

Psychol Aging. 2018 Nov;33(7):1007-1021. doi: 10.1037/pag0000294. Epub 2018 Oct 4.

PMID:
30284855
10.

Chronic Liquid Fructose, but not Glucose, Supplementation Selectively Induces Visceral Adipose Tissue Leptin Resistance and Hypertrophy in Female Sprague-Dawley Rats.

Sangüesa G, Roglans N, Montañés JC, Baena M, Velázquez AM, Sánchez RM, Alegret M, Laguna JC.

Mol Nutr Food Res. 2018 Nov;62(22):e1800777. doi: 10.1002/mnfr.201800777. Epub 2018 Oct 11.

PMID:
30260587
11.

Analysis of shared heritability in common disorders of the brain.

Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze JF, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JSK, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, Nöthen MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh KH, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HHH, Lehtimäki T, Wedenoja J, Buring JE, Schürks M, Hrafnsdottir M, Hottenga JJ, Penninx B, Artto V, Kaunisto M, Vepsäläinen S, Martin NG, Montgomery GW, Kurki MI, Hämäläinen E, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, Göbel H, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart JA, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono RJ, Catarino CB, Cossette P, De Jonghe P, Depondt C, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, Kälviäinen R, Kunz WS, Lerche H, Leu C, Lindhout D, Lo W, Lowenstein D, McCormack M, Møller RS, Molloy A, Ng PW, Oliver K, Privitera M, Radtke R, Ruppert AK, Sander T, Schachter S, Schankin C, Scheffer I, Schoch S, Sisodiya SM, Smith P, Sperling M, Striano P, Surges R, Thomas GN, Visscher F, Whelan CD, Zara F, Heinzen EL, Marson A, Becker F, Stroink H, Zimprich F, Gasser T, Gibbs R, Heutink P, Martinez M, Morris HR, Sharma M, Ryten M, Mok KY, Pulit S, Bevan S, Holliday E, Attia J, Battey T, Boncoraglio G, Thijs V, Chen WM, Mitchell B, Rothwell P, Sharma P, Sudlow C, Vicente A, Markus H, Kourkoulis C, Pera J, Raffeld M, Silliman S, Boraska Perica V, Thornton LM, Huckins LM, William Rayner N, Lewis CM, Gratacos M, Rybakowski F, Keski-Rahkonen A, Raevuori A, Hudson JI, Reichborn-Kjennerud T, Monteleone P, Karwautz A, Mannik K, Baker JH, O'Toole JK, Trace SE, Davis OSP, Helder SG, Ehrlich S, Herpertz-Dahlmann B, Danner UN, van Elburg AA, Clementi M, Forzan M, Docampo E, Lissowska J, Hauser J, Tortorella A, Maj M, Gonidakis F, Tziouvas K, Papezova H, Yilmaz Z, Wagner G, Cohen-Woods S, Herms S, Julià A, Rabionet R, Dick DM, Ripatti S, Andreassen OA, Espeseth T, Lundervold AJ, Steen VM, Pinto D, Scherer SW, Aschauer H, Schosser A, Alfredsson L, Padyukov L, Halmi KA, Mitchell J, Strober M, Bergen AW, Kaye W, Szatkiewicz JP, Cormand B, Ramos-Quiroga JA, Sánchez-Mora C, Ribasés M, Casas M, Hervas A, Arranz MJ, Haavik J, Zayats T, Johansson S, Williams N, Dempfle A, Rothenberger A, Kuntsi J, Oades RD, Banaschewski T, Franke B, Buitelaar JK, Arias Vasquez A, Doyle AE, Reif A, Lesch KP, Freitag C, Rivero O, Palmason H, Romanos M, Langley K, Rietschel M, Witt SH, Dalsgaard S, Børglum AD, Waldman I, Wilmot B, Molly N, Bau CHD, Crosbie J, Schachar R, Loo SK, McGough JJ, Grevet EH, Medland SE, Robinson E, Weiss LA, Bacchelli E, Bailey A, Bal V, Battaglia A, Betancur C, Bolton P, Cantor R, Celestino-Soper P, Dawson G, De Rubeis S, Duque F, Green A, Klauck SM, Leboyer M, Levitt P, Maestrini E, Mane S, De-Luca DM, Parr J, Regan R, Reichenberg A, Sandin S, Vorstman J, Wassink T, Wijsman E, Cook E, Santangelo S, Delorme R, Rogé B, Magalhaes T, Arking D, Schulze TG, Thompson RC, Strohmaier J, Matthews K, Melle I, Morris D, Blackwood D, McIntosh A, Bergen SE, Schalling M, Jamain S, Maaser A, Fischer SB, Reinbold CS, Fullerton JM, Guzman-Parra J, Mayoral F, Schofield PR, Cichon S, Mühleisen TW, Degenhardt F, Schumacher J, Bauer M, Mitchell PB, Gershon ES, Rice J, Potash JB, Zandi PP, Craddock N, Ferrier IN, Alda M, Rouleau GA, Turecki G, Ophoff R, Pato C, Anjorin A, Stahl E, Leber M, Czerski PM, Cruceanu C, Jones IR, Posthuma D, Andlauer TFM, Forstner AJ, Streit F, Baune BT, Air T, Sinnamon G, Wray NR, MacIntyre DJ, Porteous D, Homuth G, Rivera M, Grove J, Middeldorp CM, Hickie I, Pergadia M, Mehta D, Smit JH, Jansen R, de Geus E, Dunn E, Li QS, Nauck M, Schoevers RA, Beekman AT, Knowles JA, Viktorin A, Arnold P, Barr CL, Bedoya-Berrio G, Bienvenu OJ, Brentani H, Burton C, Camarena B, Cappi C, Cath D, Cavallini M, Cusi D, Darrow S, Denys D, Derks EM, Dietrich A, Fernandez T, Figee M, Freimer N, Gerber G, Grados M, Greenberg E, Hanna GL, Hartmann A, Hirschtritt ME, Hoekstra PJ, Huang A, Huyser C, Illmann C, Jenike M, Kuperman S, Leventhal B, Lochner C, Lyon GJ, Macciardi F, Madruga-Garrido M, Malaty IA, Maras A, McGrath L, Miguel EC, Mir P, Nestadt G, Nicolini H, Okun MS, Pakstis A, Paschou P, Piacentini J, Pittenger C, Plessen K, Ramensky V, Ramos EM, Reus V, Richter MA, Riddle MA, Robertson MM, Roessner V, Rosário M, Samuels JF, Sandor P, Stein DJ, Tsetsos F, Van Nieuwerburgh F, Weatherall S, Wendland JR, Wolanczyk T, Worbe Y, Zai G, Goes FS, McLaughlin N, Nestadt PS, Grabe HJ, Depienne C, Konkashbaev A, Lanzagorta N, Valencia-Duarte A, Bramon E, Buccola N, Cahn W, Cairns M, Chong SA, Cohen D, Crespo-Facorro B, Crowley J, Davidson M, DeLisi L, Dinan T, Donohoe G, Drapeau E, Duan J, Haan L, Hougaard D, Karachanak-Yankova S, Khrunin A, Klovins J, Kučinskas V, Lee Chee Keong J, Limborska S, Loughland C, Lönnqvist J, Maher B, Mattheisen M, McDonald C, Murphy KC, Nenadic I, van Os J, Pantelis C, Pato M, Petryshen T, Quested D, Roussos P, Sanders AR, Schall U, Schwab SG, Sim K, So HC, Stögmann E, Subramaniam M, Toncheva D, Waddington J, Walters J, Weiser M, Cheng W, Cloninger R, Curtis D, Gejman PV, Henskens F, Mattingsdal M, Oh SY, Scott R, Webb B, Breen G, Churchhouse C, Bulik CM, Daly M, Dichgans M, Faraone SV, Guerreiro R, Holmans P, Kendler KS, Koeleman B, Mathews CA, Price A, Scharf J, Sklar P, Williams J, Wood NW, Cotsapas C, Palotie A, Smoller JW, Sullivan P, Rosand J, Corvin A, Neale BM, Schott JM, Anney R, Elia J, Grigoroiu-Serbanescu M, Edenberg HJ, Murray R.

Science. 2018 Jun 22;360(6395). pii: eaap8757. doi: 10.1126/science.aap8757.

12.

Genome-wide significant risk factors on chromosome 19 and the APOE locus.

Moreno-Grau S, Hernández I, Heilmann-Heimbach S, Ruiz S, Rosende-Roca M, Mauleón A, Vargas L, Rodríguez-Gómez O, Alegret M, Espinosa A, Ortega G, Aguilera N, Abdelnour C, Neuroimaging Initiative AD, Gil S, Maier W, Sotolongo-Grau O, Tárraga L, Ramirez A, López-Arrrieta J, Antúnez C, Serrano-Ríos M, Boada M, Ruiz A.

Oncotarget. 2018 May 15;9(37):24590-24600. doi: 10.18632/oncotarget.25083. eCollection 2018 May 15.

13.

Differential effects of high consumption of fructose or glucose on mesenteric arterial function in female rats.

Shaligram S, Sangüesa G, Akther F, Alegret M, Laguna JC, Rahimian R.

J Nutr Biochem. 2018 Jul;57:136-144. doi: 10.1016/j.jnutbio.2018.03.021. Epub 2018 Apr 3.

14.

Patient Engagement: The Fundació ACE Framework for Improving Recruitment and Retention in Alzheimer's Disease Research.

Boada M, Santos-Santos MA, Rodríguez-Gómez O, Alegret M, Cañabate P, Lafuente A, Abdelnour C, Buendía M, de Dios MJ, Morera A, Sanabria Á, Campo L, Ruiz A, Tárraga L.

J Alzheimers Dis. 2018;62(3):1079-1090. doi: 10.3233/JAD-170866. Review. Erratum in: J Alzheimers Dis. 2018;63(3):1207.

15.

Chronic fructose intake does not induce liver steatosis and inflammation in female Sprague-Dawley rats, but causes hypertriglyceridemia related to decreased VLDL receptor expression.

Sangüesa G, Montañés JC, Baena M, Sánchez RM, Roglans N, Alegret M, Laguna JC.

Eur J Nutr. 2019 Apr;58(3):1283-1297. doi: 10.1007/s00394-018-1654-9. Epub 2018 Mar 7.

PMID:
29516226
16.

The Spanish version of Face-Name Associative Memory Exam (S-FNAME) performance is related to amyloid burden in Subjective Cognitive Decline.

Sanabria A, Alegret M, Rodriguez-Gomez O, Valero S, Sotolongo-Grau O, Monté-Rubio G, Abdelnour C, Espinosa A, Ortega G, Perez-Cordon A, Gailhajanet A, Hernandez I, Rosende-Roca M, Vargas L, Mauleon A, Sanchez D, Martin E, Rentz DM, Lomeña F, Ruiz A, Tarraga L, Boada M; FACEHBI study group.

Sci Rep. 2018 Feb 28;8(1):3828. doi: 10.1038/s41598-018-21644-y.

17.

The Role of Verb Fluency in the Detection of Early Cognitive Impairment in Alzheimer's Disease.

Alegret M, Peretó M, Pérez A, Valero S, Espinosa A, Ortega G, Hernández I, Mauleón A, Rosende-Roca M, Vargas L, Rodríguez-Gómez O, Abdelnour C, Berthier ML, Bak TH, Ruíz A, Tárraga L, Boada M.

J Alzheimers Dis. 2018;62(2):611-619. doi: 10.3233/JAD-170826.

PMID:
29480180
18.

Impairment of Novel Object Recognition Memory and Brain Insulin Signaling in Fructose- but Not Glucose-Drinking Female Rats.

Sangüesa G, Cascales M, Griñán C, Sánchez RM, Roglans N, Pallàs M, Laguna JC, Alegret M.

Mol Neurobiol. 2018 Aug;55(8):6984-6999. doi: 10.1007/s12035-017-0863-1. Epub 2018 Jan 26.

PMID:
29372547
19.

FACEHBI: A Prospective Study of Risk Factors, Biomarkers and Cognition in a Cohort of Individuals with Subjective Cognitive Decline. Study Rationale and Research Protocols.

Rodriguez-Gomez O, Sanabria A, Perez-Cordon A, Sanchez-Ruiz D, Abdelnour C, Valero S, Hernandez I, Rosende-Roca M, Mauleon A, Vargas L, Alegret M, Espinosa A, Ortega G, Guitart M, Gailhajanet A, Sotolongo-Grau O, Moreno-Grau S, Ruiz S, Tarragona M, Serra J, Martin E, Peleja E, Lomeña F, Campos F, Vivas A, Gomez-Chiari M, Tejero MA, Giménez J, Pesini P, Sarasa M, Martinez G, Ruiz A, Tarraga L, Boada M.

J Prev Alzheimers Dis. 2017;4(2):100-108. doi: 10.14283/jpad.2016.122.

PMID:
29186280
20.

Exploring APOE genotype effects on Alzheimer's disease risk and amyloid β burden in individuals with subjective cognitive decline: The FundacioACE Healthy Brain Initiative (FACEHBI) study baseline results.

Moreno-Grau S, Rodríguez-Gómez O, Sanabria Á, Pérez-Cordón A, Sánchez-Ruiz D, Abdelnour C, Valero S, Hernández I, Rosende-Roca M, Mauleón A, Vargas L, Lafuente A, Gil S, Santos-Santos MÁ, Alegret M, Espinosa A, Ortega G, Guitart M, Gailhajanet A, de Rojas I, Sotolongo-Grau Ó, Ruiz S, Aguilera N, Papasey J, Martín E, Peleja E; Alzheimer's Disease Neuroimaging Initiative, Lomeña F, Campos F, Vivas A, Gómez-Chiari M, Tejero MÁ, Giménez J, Serrano-Ríos M, Orellana A, Tárraga L, Ruiz A, Boada M; FACEHBI study group.

Alzheimers Dement. 2018 May;14(5):634-643. doi: 10.1016/j.jalz.2017.10.005. Epub 2017 Nov 20.

21.

Type 2 diabetes is an independent risk factor for dementia conversion in patients with mild cognitive impairment.

Ciudin A, Espinosa A, Simó-Servat O, Ruiz A, Alegret M, Hernández C, Boada M, Simó R.

J Diabetes Complications. 2017 Aug;31(8):1272-1274. doi: 10.1016/j.jdiacomp.2017.04.018. Epub 2017 Apr 19.

PMID:
28545893
22.

Social Representation of Dementia: An Analysis of 5,792 Consecutive Cases Evaluated in a Memory Clinic.

Cañabate P, Martínez G, Rosende-Roca M, Moreno M, Preckler S, Valero S, Sotolongo O, Hernández I, Alegret M, Ortega G, Espinosa A, Mauleón A, Vargas L, Rodríguez O, Abdelnour C, Sánchez D, Martín E, Ruiz A, Tárraga L, Boada M.

J Alzheimers Dis. 2017;58(4):1099-1108. doi: 10.3233/JAD-161119.

23.

The Addition of Liquid Fructose to a Western-Type Diet in LDL-R-/- Mice Induces Liver Inflammation and Fibrogenesis Markers without Disrupting Insulin Receptor Signalling after an Insulin Challenge.

Sangüesa G, Baena M, Hutter N, Montañés JC, Sánchez RM, Roglans N, Laguna JC, Alegret M.

Nutrients. 2017 Mar 15;9(3). pii: E278. doi: 10.3390/nu9030278.

24.

Cognitive Composites Domain Scores Related to Neuroimaging Biomarkers within Probable-Amnestic Mild Cognitive Impairment-Storage Subtype.

Espinosa A, Alegret M, Pesini P, Valero S, Lafuente A, Buendía M, San José I, Ibarria M, Tejero MA, Giménez J, Ruiz S, Hernández I, Pujadas F, Martínez-Lage P, Munuera J, Arbizu J, Tárraga L, Hendrix SB, Ruiz A, Becker JT, Landau SM, Sotolongo-Grau O, Sarasa M, Boada M; AB255 Study Group; Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2017;57(2):447-459. doi: 10.3233/JAD-161223.

25.

Impact of Recruitment Methods in Subjective Cognitive Decline.

Abdelnour C, Rodríguez-Gómez O, Alegret M, Valero S, Moreno-Grau S, Sanabria Á, Hernández I, Rosende-Roca M, Vargas L, Mauleón A, Sánchez D, Espinosa A, Ortega G, Pérez-Cordón A, Diego S, Gailhajanet A, Guitart M, Sotolongo-Grau Ó, Ruiz A, Tárraga L, Boada M.

J Alzheimers Dis. 2017;57(2):625-632. doi: 10.3233/JAD-160915.

PMID:
28269773
26.

The impact of automated hippocampal volumetry on diagnostic confidence in patients with suspected Alzheimer's disease: A European Alzheimer's Disease Consortium study.

Bosco P, Redolfi A, Bocchetta M, Ferrari C, Mega A, Galluzzi S, Austin M, Chincarini A, Collins DL, Duchesne S, Maréchal B, Roche A, Sensi F, Wolz R, Alegret M, Assal F, Balasa M, Bastin C, Bougea A, Emek-Savaş DD, Engelborghs S, Grimmer T, Grosu G, Kramberger MG, Lawlor B, Mandic Stojmenovic G, Marinescu M, Mecocci P, Molinuevo JL, Morais R, Niemantsverdriet E, Nobili F, Ntovas K, O'Dwyer S, Paraskevas GP, Pelini L, Picco A, Salmon E, Santana I, Sotolongo-Grau O, Spiru L, Stefanova E, Popovic KS, Tsolaki M, Yener GG, Zekry D, Frisoni GB.

Alzheimers Dement. 2017 Sep;13(9):1013-1023. doi: 10.1016/j.jalz.2017.01.019. Epub 2017 Mar 3.

PMID:
28263741
27.

Type of supplemented simple sugar, not merely calorie intake, determines adverse effects on metabolism and aortic function in female rats.

Sangüesa G, Shaligram S, Akther F, Roglans N, Laguna JC, Rahimian R, Alegret M.

Am J Physiol Heart Circ Physiol. 2017 Feb 1;312(2):H289-H304. doi: 10.1152/ajpheart.00339.2016. Epub 2016 Dec 6.

28.

Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer's Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial.

Boada M, Anaya F, Ortiz P, Olazarán J, Shua-Haim JR, Obisesan TO, Hernández I, Muñoz J, Buendia M, Alegret M, Lafuente A, Tárraga L, Núñez L, Torres M, Grifols JR, Ferrer I, Lopez OL, Páez A.

J Alzheimers Dis. 2017;56(1):129-143. doi: 10.3233/JAD-160565.

29.

Liquid fructose in Western-diet-fed mice impairs liver insulin signaling and causes cholesterol and triglyceride loading without changing calorie intake and body weight.

Baena M, Sangüesa G, Hutter N, Beltrán JM, Sánchez RM, Roglans N, Alegret M, Laguna JC.

J Nutr Biochem. 2017 Feb;40:105-115. doi: 10.1016/j.jnutbio.2016.10.015. Epub 2016 Nov 2.

PMID:
27883935
30.

Fructose, but not glucose, impairs insulin signaling in the three major insulin-sensitive tissues.

Baena M, Sangüesa G, Dávalos A, Latasa MJ, Sala-Vila A, Sánchez RM, Roglans N, Laguna JC, Alegret M.

Sci Rep. 2016 May 19;6:26149. doi: 10.1038/srep26149.

31.

Genome-wide significant risk factors for Alzheimer's disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment.

Lacour A, Espinosa A, Louwersheimer E, Heilmann S, Hernández I, Wolfsgruber S, Fernández V, Wagner H, Rosende-Roca M, Mauleón A, Moreno-Grau S, Vargas L, Pijnenburg YA, Koene T, Rodríguez-Gómez O, Ortega G, Ruiz S, Holstege H, Sotolongo-Grau O, Kornhuber J, Peters O, Frölich L, Hüll M, Rüther E, Wiltfang J, Scherer M, Riedel-Heller S, Alegret M, Nöthen MM, Scheltens P, Wagner M, Tárraga L, Jessen F, Boada M, Maier W, van der Flier WM, Becker T, Ramirez A, Ruiz A.

Mol Psychiatry. 2017 Jan;22(1):153-160. doi: 10.1038/mp.2016.18. Epub 2016 Mar 15.

32.

Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment.

Louwersheimer E, Wolfsgruber S, Espinosa A, Lacour A, Heilmann-Heimbach S, Alegret M, Hernández I, Rosende-Roca M, Tárraga L, Boada M, Kornhuber J, Peters O, Frölich L, Hüll M, Rüther E, Wiltfang J, Scherer M, Riedel-Heller S, Jessen F, Nöthen MM, Maier W, Koene T, Scheltens P, Holstege H, Wagner M, Ruiz A, van der Flier WM, Becker T, Ramirez A.

Alzheimers Dement. 2016 Aug;12(8):872-81. doi: 10.1016/j.jalz.2016.01.006. Epub 2016 Feb 26.

33.

Beneficial Effects of an Integrated Psychostimulation Program in Patients with Alzheimer's Disease.

Ibarria M, Alegret M, Valero S, Morera A, Guitart M, Cañabate P, Moreno M, Lara S, Diego S, Hernández J, Tantinyá N, Vera M, Hernández I, Becker JT, Ruíz A, Boada M, Tárraga L.

J Alzheimers Dis. 2016;50(2):559-66. doi: 10.3233/JAD-150455.

34.

Concordance between Subjective and Objective Memory Impairment in Volunteer Subjects.

Alegret M, Rodríguez O, Espinosa A, Ortega G, Sanabria A, Valero S, Hernández I, Rosende-Roca M, Vargas L, Abdelnour C, Mauleón A, Gailhajanet A, Martín E, Tárraga L, Rentz DM, Amariglio RE, Ruíz A, Boada M.

J Alzheimers Dis. 2015;48(4):1109-17. doi: 10.3233/JAD-150594.

PMID:
26444795
35.

Validation of the Spanish Version of the Face Name Associative Memory Exam (S-FNAME) in Cognitively Normal Older Individuals.

Alegret M, Valero S, Ortega G, Espinosa A, Sanabria A, Hernández I, Rodríguez O, Rosende-Roca M, Mauleón A, Vargas L, Martín E, Ruíz A, Tárraga L, Amariglio RE, Rentz DM, Boada M.

Arch Clin Neuropsychol. 2015 Nov;30(7):712-20. doi: 10.1093/arclin/acv050. Epub 2015 Aug 18.

36.

PLD3 in non-familial Alzheimer's disease.

Heilmann S, Drichel D, Clarimon J, Fernández V, Lacour A, Wagner H, Thelen M, Hernández I, Fortea J, Alegret M, Blesa R, Mauleón A, Roca MR, Kornhuber J, Peters O, Heun R, Frölich L, Hüll M, Heneka MT, Rüther E, Riedel-Heller S, Scherer M, Wiltfang J, Jessen F, Becker T, Tárraga L, Boada M, Maier W, Lleó A, Ruiz A, Nöthen MM, Ramirez A.

Nature. 2015 Apr 2;520(7545):E3-5. doi: 10.1038/nature14039. No abstract available.

PMID:
25832411
37.

Hypercholesterolemia and neurodegeneration. Comparison of hippocampal phenotypes in LDLr knockout and APPswe/PS1dE9 mice.

Ettcheto M, Petrov D, Pedrós I, de Lemos L, Pallàs M, Alegret M, Laguna JC, Folch J, Camins A.

Exp Gerontol. 2015 May;65:69-78. doi: 10.1016/j.exger.2015.03.010. Epub 2015 Mar 20.

PMID:
25797218
38.

Differentiated clinical presentation of early and late-onset Alzheimer's disease: is 65 years of age providing a reliable threshold?

Palasí A, Gutiérrez-Iglesias B, Alegret M, Pujadas F, Olabarrieta M, Liébana D, Quintana M, Álvarez-Sabín J, Boada M.

J Neurol. 2015 May;262(5):1238-46. doi: 10.1007/s00415-015-7698-3. Epub 2015 Mar 21.

PMID:
25791224
39.

Evaluation of Candidate Genes Related to Neuronal Apoptosis in Late-Onset Alzheimer’s Disease.

Moreno-Grau S, Barneda B, Carriba P, Marín J, Sotolongo-Grau O, Hernández I, Rosende-Roca M, Mauleón A, Vargas L, Espinosa A, Alegret M, Rodriguez O, Ortega G, Fernández MV, López-Arrieta J, Tárraga L, Boada M, Antúnez C, López J, Ruiz A, Comella JX.

J Alzheimers Dis. 2015;45(2):621-9.

PMID:
25613099
40.

Simple sugar intake and hepatocellular carcinoma: epidemiological and mechanistic insight.

Laguna JC, Alegret M, Roglans N.

Nutrients. 2014 Dec 22;6(12):5933-54. doi: 10.3390/nu6125933. Review.

41.

Fructose supplementation impairs rat liver autophagy through mTORC activation without inducing endoplasmic reticulum stress.

Baena M, Sangüesa G, Hutter N, Sánchez RM, Roglans N, Laguna JC, Alegret M.

Biochim Biophys Acta. 2015 Feb;1851(2):107-16. doi: 10.1016/j.bbalip.2014.11.003. Epub 2014 Nov 9.

PMID:
25463011
42.

Erratum to "Exploratory analysis of seven Alzheimer's disease genes: disease progression" [Neurobiol. Aging 34 (2013) 1310.e1-1310.e7].

Ruiz A, Hernández I, Ronsende-Roca M, González-Pérez A, Rodriguez-Noriega E, Ramírez-Lorca R, Mauleón A, Moreno-Rey C, Boswell L, Tune L, Valero S, Alegret M, Gayán J, Becker JT, Real LM, Tárraga L, Ballard C, Terrin M, Sherman S, Payami H, López OL, Mintzer JE, Boada M.

Neurobiol Aging. 2014 Nov;35(11):2661. doi: 10.1016/j.neurobiolaging.2014.06.016. Epub 2014 Sep 17. No abstract available.

PMID:
28911722
43.

Association of TMEM106B rs1990622 marker and frontotemporal dementia: evidence for a recessive effect and meta-analysis.

Hernández I, Rosende-Roca M, Alegret M, Mauleón A, Espinosa A, Vargas L, Sotolongo-Grau O, Tárraga L, Boada M, Ruiz A.

J Alzheimers Dis. 2015;43(1):325-34. doi: 10.3233/JAD-132432.

PMID:
25096617
44.

Cognitive, genetic, and brain perfusion factors associated with four year incidence of Alzheimer's disease from mild cognitive impairment.

Alegret M, Cuberas-Borrós G, Espinosa A, Valero S, Hernández I, Ruíz A, Becker JT, Rosende-Roca M, Mauleón A, Sotolongo O, Castell-Conesa J, Roca I, Tárraga L, Boada M.

J Alzheimers Dis. 2014;41(3):739-48. doi: 10.3233/JAD-132516.

45.

Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene.

Ruiz A, Heilmann S, Becker T, Hernández I, Wagner H, Thelen M, Mauleón A, Rosende-Roca M, Bellenguez C, Bis JC, Harold D, Gerrish A, Sims R, Sotolongo-Grau O, Espinosa A, Alegret M, Arrieta JL, Lacour A, Leber M, Becker J, Lafuente A, Ruiz S, Vargas L, Rodríguez O, Ortega G, Dominguez MA; IGAP, Mayeux R, Haines JL, Pericak-Vance MA, Farrer LA, Schellenberg GD, Chouraki V, Launer LJ, van Duijn C, Seshadri S, Antúnez C, Breteler MM, Serrano-Ríos M, Jessen F, Tárraga L, Nöthen MM, Maier W, Boada M, Ramírez A.

Transl Psychiatry. 2014 Feb 4;4:e358. doi: 10.1038/tp.2014.2.

46.

Liquid fructose down-regulates liver insulin receptor substrate 2 and gluconeogenic enzymes by modifying nutrient sensing factors in rats.

Rebollo A, Roglans N, Baena M, Padrosa A, Sánchez RM, Merlos M, Alegret M, Laguna JC.

J Nutr Biochem. 2014 Feb;25(2):250-8. doi: 10.1016/j.jnutbio.2013.10.014. Epub 2013 Nov 22.

47.

Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells.

Rebollo A, Roglans N, Baena M, Sánchez RM, Merlos M, Alegret M, Laguna JC.

Biochim Biophys Acta. 2014 Apr 4;1841(4):514-24. doi: 10.1016/j.bbalip.2014.01.002. Epub 2014 Jan 13.

48.

Identification of misdiagnosed fronto-temporal dementia using APOE genotype and phenotype-genotype correlation analyses.

Hernández I, Mauleón A, Rosense-Roca M, Alegret M, Vinyes G, Espinosa A, Sotolongo-Grau O, Becker JT, Valero S, Tarraga L, López OL, Ruiz A, Boada M.

Curr Alzheimer Res. 2014 Feb;11(2):182-91.

49.

Blood amyloid beta levels in healthy, mild cognitive impairment and Alzheimer's disease individuals: replication of diastolic blood pressure correlations and analysis of critical covariates.

Ruiz A, Pesini P, Espinosa A, Pérez-Grijalba V, Valero S, Sotolongo-Grau O, Alegret M, Monleón I, Lafuente A, Buendía M, Ibarria M, Ruiz S, Hernández I, San José I, Tárraga L, Boada M, Sarasa M.

PLoS One. 2013 Nov 27;8(11):e81334. doi: 10.1371/journal.pone.0081334. eCollection 2013.

50.

Cut-off scores of a brief neuropsychological battery (NBACE) for Spanish individual adults older than 44 years old.

Alegret M, Espinosa A, Valero S, Vinyes-Junqué G, Ruiz A, Hernández I, Rosende-Roca M, Mauleón A, Becker JT, Tárraga L, Boada M.

PLoS One. 2013 Oct 16;8(10):e76436. doi: 10.1371/journal.pone.0076436. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/acefbfc7-8fb6-4505-a273-0fdb4e2bb580.

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