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Items: 27


Development of a Pan-H1 Influenza Vaccine.

Darricarrère N, Pougatcheva S, Duan X, Rudicell RS, Chou TH, DiNapoli J, Ross TM, Alefantis T, Vogel TU, Kleanthous H, Wei CJ, Nabel GJ.

J Virol. 2018 Oct 29;92(22). pii: e01349-18. doi: 10.1128/JVI.01349-18. Print 2018 Nov 15.


A multimechanistic antibody targeting the receptor binding site potently cross-protects against influenza B viruses.

Shen C, Chen J, Li R, Zhang M, Wang G, Stegalkina S, Zhang L, Chen J, Cao J, Bi X, Anderson SF, Alefantis T, Zhang M, Cai X, Yang K, Zheng Q, Fang M, Yu H, Luo W, Zheng Z, Yuan Q, Zhang J, Wai-Kuo Shih J, Kleanthous H, Chen H, Chen Y, Xia N.

Sci Transl Med. 2017 Oct 18;9(412). pii: eaam5752. doi: 10.1126/scitranslmed.aam5752.


Computationally Optimized Broadly Reactive Hemagglutinin Elicits Hemagglutination Inhibition Antibodies against a Panel of H3N2 Influenza Virus Cocirculating Variants.

Wong TM, Allen JD, Bebin-Blackwell AG, Carter DM, Alefantis T, DiNapoli J, Kleanthous H, Ross TM.

J Virol. 2017 Nov 30;91(24). pii: e01581-17. doi: 10.1128/JVI.01581-17. Print 2017 Dec 15.


Iron-dependent reconfiguration of the proteome underlies the intracellular lifestyle of Brucella abortus.

Roset MS, Alefantis TG, DelVecchio VG, Briones G.

Sci Rep. 2017 Sep 6;7(1):10637. doi: 10.1038/s41598-017-11283-0.


Design and Characterization of a Computationally Optimized Broadly Reactive Hemagglutinin Vaccine for H1N1 Influenza Viruses.

Carter DM, Darby CA, Lefoley BC, Crevar CJ, Alefantis T, Oomen R, Anderson SF, Strugnell T, Cortés-Garcia G, Vogel TU, Parrington M, Kleanthous H, Ross TM.

J Virol. 2016 Apr 14;90(9):4720-4734. doi: 10.1128/JVI.03152-15. Print 2016 May.


Self-adjuvanting bacterial vectors expressing pre-erythrocytic antigens induce sterile protection against malaria.

Bergmann-Leitner ES, Hosie H, Trichilo J, Deriso E, Ranallo RT, Alefantis T, Savranskaya T, Grewal P, Ockenhouse CF, Venkatesan MM, Delvecchio VG, Angov E.

Front Immunol. 2013 Jul 4;4:176. doi: 10.3389/fimmu.2013.00176. eCollection 2013.


Comparative proteomic profiling of culture filtrate proteins of less and highly virulent Francisella tularensis strains.

Konecna K, Hernychova L, Reichelova M, Lenco J, Klimentova J, Stulik J, Macela A, Alefantis T, Delvecchio VG.

Proteomics. 2010 Dec;10(24):4501-11. doi: 10.1002/pmic.201000248. Epub 2010 Nov 9.


Identification of essential filovirion-associated host factors by serial proteomic analysis and RNAi screen.

Spurgers KB, Alefantis T, Peyser BD, Ruthel GT, Bergeron AA, Costantino JA, Enterlein S, Kota KP, Boltz RC, Aman MJ, Delvecchio VG, Bavari S.

Mol Cell Proteomics. 2010 Dec;9(12):2690-703. doi: 10.1074/mcp.M110.003418. Epub 2010 Aug 11.


Proteomics for the development of vaccines and therapeutics.

DelVecchio VG, Sabato MA, Trichilo J, Dake C, Grewal P, Alefantis T.

Crit Rev Immunol. 2010;30(3):239-54. Review.


Identification of human T cell leukemia virus type 1 tax amino acid signals and cellular factors involved in secretion of the viral oncoprotein.

Jain P, Mostoller K, Flaig KE, Ahuja J, Lepoutre V, Alefantis T, Khan ZK, Wigdahl B.

J Biol Chem. 2007 Nov 23;282(47):34581-93. Epub 2007 Sep 26.


Bacillus anthracis secretome time course under host-simulated conditions and identification of immunogenic proteins.

Walz A, Mujer CV, Connolly JP, Alefantis T, Chafin R, Dake C, Whittington J, Kumar SP, Khan AS, DelVecchio VG.

Proteome Sci. 2007 Jul 27;5:11.


Interaction of HTLV-1 Tax protein with calreticulin: implications for Tax nuclear export and secretion.

Alefantis T, Flaig KE, Wigdahl B, Jain P.

Biomed Pharmacother. 2007 May;61(4):194-200. Epub 2007 Mar 9.


Proteomic profiling and identification of immunodominant spore antigens of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis.

Delvecchio VG, Connolly JP, Alefantis TG, Walz A, Quan MA, Patra G, Ashton JM, Whittington JT, Chafin RD, Liang X, Grewal P, Khan AS, Mujer CV.

Appl Environ Microbiol. 2006 Sep;72(9):6355-63.


Identification of protein candidates for developing bacterial ghost vaccines against Brucella.

DelVecchio VG, Alefantis T, Ugalde RA, Comerci D, Marchesini MI, Khan A, Lubitz W, Mujer CV.

Methods Biochem Anal. 2006;49:363-77. Review. No abstract available.


AP-1-directed human T cell leukemia virus type 1 viral gene expression during monocytic differentiation.

Grant C, Jain P, Nonnemacher M, Flaig KE, Irish B, Ahuja J, Alexaki A, Alefantis T, Wigdahl B.

J Leukoc Biol. 2006 Sep;80(3):640-50. Epub 2006 Jul 7.


Proteomic analysis of Brucella abortus cell envelope and identification of immunogenic candidate proteins for vaccine development.

Connolly JP, Comerci D, Alefantis TG, Walz A, Quan M, Chafin R, Grewal P, Mujer CV, Ugalde RA, DelVecchio VG.

Proteomics. 2006 Jul;6(13):3767-80.


Regulation of human T-cell leukemia virus type 1 gene expression by Sp1 and Sp3 interaction with TRE-1 repeat III.

Yao J, Grant C, Harhaj E, Nonnemacher M, Alefantis T, Martin J, Jain P, Wigdahl B.

DNA Cell Biol. 2006 May;25(5):262-76.


Proteomics and bioinformatics strategies to design countermeasures against infectious threat agents.

Khan AS, Mujer CV, Alefantis TG, Connolly JP, Mayr UB, Walcher P, Lubitz W, Delvecchio VG.

J Chem Inf Model. 2006 Jan-Feb;46(1):111-5.


HTLV-1 Tax nucleocytoplasmic shuttling, interaction with the secretory pathway, extracellular signaling, and implications for neurologic disease.

Alefantis T, Jain P, Ahuja J, Mostoller K, Wigdahl B.

J Biomed Sci. 2005 Dec;12(6):961-74. Epub 2005 Oct 14. Review.


Human T cell leukemia virus type I Tax activates CD40 gene expression via the NF-kappa B pathway.

Harhaj EW, Harhaj NS, Grant C, Mostoller K, Alefantis T, Sun SC, Wigdahl B.

Virology. 2005 Mar 1;333(1):145-58.


Secretion of the human T cell leukemia virus type I transactivator protein tax.

Alefantis T, Mostoller K, Jain P, Harhaj E, Grant C, Wigdahl B.

J Biol Chem. 2005 Apr 29;280(17):17353-62. Epub 2005 Jan 19.


Antigen discovery and delivery of subunit vaccines by nonliving bacterial ghost vectors.

Walcher P, Mayr UB, Azimpour-Tabrizi C, Eko FO, Jechlinger W, Mayrhofer P, Alefantis T, Mujer CV, DelVecchio VG, Lubitz W.

Expert Rev Vaccines. 2004 Dec;3(6):681-91. Review.


A rapid and sensitive magnetic bead-based immunoassay for the detection of staphylococcal enterotoxin B for high-through put screening.

Alefantis T, Grewal P, Ashton J, Khan AS, Valdes JJ, Del Vecchio VG.

Mol Cell Probes. 2004 Dec;18(6):379-82.


Human T cell leukemia virus type I-induced disease: pathways to cancer and neurodegeneration.

Barmak K, Harhaj E, Grant C, Alefantis T, Wigdahl B.

Virology. 2003 Mar 30;308(1):1-12. Review.


Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax.

Alefantis T, Barmak K, Harhaj EW, Grant C, Wigdahl B.

J Biol Chem. 2003 Jun 13;278(24):21814-22. Epub 2003 Apr 1.


Detection of duck enteritis virus by polymerase chain reaction.

Plummer PJ, Alefantis T, Kaplan S, O'Connell P, Shawky S, Schat KA.

Avian Dis. 1998 Jul-Sep;42(3):554-64.


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