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Targeted AKT Inhibition in Prostate Cancer Cells and Spheroids Reduces Aerobic Glycolysis and Generation of Hyperpolarized [1-13C] Lactate.

Tee SS, Suster I, Truong S, Jeong S, Eskandari R, DiGialleonardo V, Alvarez JA, Aldeborgh HN, Keshari KR.

Mol Cancer Res. 2018 Mar;16(3):453-460. doi: 10.1158/1541-7786.MCR-17-0458. Epub 2018 Jan 12.


Multinuclear NMR and MRI Reveal an Early Metabolic Response to mTOR Inhibition in Sarcoma.

Di Gialleonardo V, Aldeborgh HN, Miloushev V, Folkers KM, Granlund K, Tap WD, Lewis JS, Weber WA, Keshari KR.

Cancer Res. 2017 Jun 1;77(11):3113-3120. doi: 10.1158/0008-5472.CAN-16-3310. Epub 2017 Apr 6.


High-Throughput Indirect Quantitation of 13C Enriched Metabolites Using 1H NMR.

Di Gialleonardo V, Tee SS, Aldeborgh HN, Miloushev VZ, Cunha LS, Sukenick GD, Keshari KR.

Anal Chem. 2016 Nov 15;88(22):11147-11153. Epub 2016 Oct 26.


Sampling Hyperpolarized Molecules Utilizing a 1 Tesla Permanent Magnetic Field.

Tee SS, DiGialleonardo V, Eskandari R, Jeong S, Granlund KL, Miloushev V, Poot AJ, Truong S, Alvarez JA, Aldeborgh HN, Keshari KR.

Sci Rep. 2016 Sep 6;6:32846. doi: 10.1038/srep32846.

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