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Items: 1 to 50 of 85

1.

HIV-1 Nef Hijacks Lck and Rac1 Endosomal Traffic To Dually Modulate Signaling-Mediated and Actin Cytoskeleton-Mediated T Cell Functions.

Del Río-Iñiguez I, Vázquez-Chávez E, Cuche C, Di Bartolo V, Bouchet J, Alcover A.

J Immunol. 2018 Nov 1;201(9):2624-2640. doi: 10.4049/jimmunol.1800372. Epub 2018 Oct 3.

2.

Cell Biology of T Cell Receptor Expression and Regulation.

Alcover A, Alarcón B, Di Bartolo V.

Annu Rev Immunol. 2018 Apr 26;36:103-125. doi: 10.1146/annurev-immunol-042617-053429. Epub 2017 Dec 20. Review.

PMID:
29261409
3.

Adenomatous Polyposis Coli Defines Treg Differentiation and Anti-inflammatory Function through Microtubule-Mediated NFAT Localization.

Agüera-González S, Burton OT, Vázquez-Chávez E, Cuche C, Herit F, Bouchet J, Lasserre R, Del Río-Iñiguez I, Di Bartolo V, Alcover A.

Cell Rep. 2017 Oct 3;21(1):181-194. doi: 10.1016/j.celrep.2017.09.020.

4.

Studying the Immune Synapse in HIV-1 Infection.

Del Río-Iñiguez I, Bouchet J, Alcover A.

Methods Mol Biol. 2017;1584:545-557. doi: 10.1007/978-1-4939-6881-7_34.

5.

Imaging Vesicular Traffic at the Immune Synapse.

Bouchet J, Del Río-Iñiguez I, Alcover A.

Methods Mol Biol. 2017;1584:129-142. doi: 10.1007/978-1-4939-6881-7_9.

6.

Rab11-FIP3 Regulation of Lck Endosomal Traffic Controls TCR Signal Transduction.

Bouchet J, Del Río-Iñiguez I, Vázquez-Chávez E, Lasserre R, Agüera-González S, Cuche C, McCaffrey MW, Di Bartolo V, Alcover A.

J Immunol. 2017 Apr 1;198(7):2967-2978. doi: 10.4049/jimmunol.1600671. Epub 2017 Feb 24.

7.

Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function.

Navas VH, Cuche C, Alcover A, Di Bartolo V.

PLoS One. 2017 Jan 20;12(1):e0170396. doi: 10.1371/journal.pone.0170396. eCollection 2017.

8.

Editorial: Molecular Dynamics at the Immunological Synapse.

Alcover A, Di Bartolo V, Roda-Navarro P.

Front Immunol. 2016 Dec 21;7:632. doi: 10.3389/fimmu.2016.00632. eCollection 2016. No abstract available.

9.

The functional interplay of Rab11, FIP3 and Rho proteins on the endosomal recycling pathway controls cell shape and symmetry.

Bouchet J, McCaffrey MW, Graziani A, Alcover A.

Small GTPases. 2018 Jul 4;9(4):310-315. doi: 10.1080/21541248.2016.1224288. Epub 2016 Sep 2. Review.

10.

Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation.

Bouchet J, Del Río-Iñiguez I, Lasserre R, Agüera-Gonzalez S, Cuche C, Danckaert A, McCaffrey MW, Di Bartolo V, Alcover A.

EMBO J. 2016 Jun 1;35(11):1160-74. doi: 10.15252/embj.201593274. Epub 2016 May 6.

11.

Comparative Anatomy of Phagocytic and Immunological Synapses.

Niedergang F, Di Bartolo V, Alcover A.

Front Immunol. 2016 Jan 28;7:18. doi: 10.3389/fimmu.2016.00018. eCollection 2016. Review.

12.

Group Selection and Contribution of Minority Variants during Virus Adaptation Determines Virus Fitness and Phenotype.

Bordería AV, Isakov O, Moratorio G, Henningsson R, Agüera-González S, Organtini L, Gnädig NF, Blanc H, Alcover A, Hafenstein S, Fontes M, Shomron N, Vignuzzi M.

PLoS Pathog. 2015 May 5;11(5):e1004838. doi: 10.1371/journal.ppat.1004838. eCollection 2015 May.

13.

[Immunological synapse is a dynamic signaling platform for T cell activation].

Bouchet J, Alcover A.

Med Sci (Paris). 2014 Jun-Jul;30(6-7):665-70. doi: 10.1051/medsci/20143006017. Epub 2014 Jul 11. Review. French.

14.

Orchestrating cytoskeleton and intracellular vesicle traffic to build functional immunological synapses.

Soares H, Lasserre R, Alcover A.

Immunol Rev. 2013 Nov;256(1):118-32. doi: 10.1111/imr.12110. Review.

PMID:
24117817
15.

Regulated vesicle fusion generates signaling nanoterritories that control T cell activation at the immunological synapse.

Soares H, Henriques R, Sachse M, Ventimiglia L, Alonso MA, Zimmer C, Thoulouze MI, Alcover A.

J Exp Med. 2013 Oct 21;210(11):2415-33. doi: 10.1084/jem.20130150. Epub 2013 Oct 7.

16.

Microtubule dynamics and signal transduction at the immunological synapse: new partners and new connections.

Lasserre R, Alcover A.

EMBO J. 2012 Nov 5;31(21):4100-2. doi: 10.1038/emboj.2012.276. Epub 2012 Oct 9. No abstract available.

17.

Ezrin/radixin/moesin are required for the purinergic P2X7 receptor (P2X7R)-dependent processing of the amyloid precursor protein.

Darmellah A, Rayah A, Auger R, Cuif MH, Prigent M, Arpin M, Alcover A, Delarasse C, Kanellopoulos JM.

J Biol Chem. 2012 Oct 5;287(41):34583-95. doi: 10.1074/jbc.M112.400010. Epub 2012 Aug 13.

18.

Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation.

Lasserre R, Cuche C, Blecher-Gonen R, Libman E, Biquand E, Danckaert A, Yablonski D, Alcover A, Di Bartolo V.

J Cell Biol. 2011 Nov 28;195(5):839-53. doi: 10.1083/jcb.201103105. Epub 2011 Nov 21.

19.

Can viruses form biofilms?

Thoulouze MI, Alcover A.

Trends Microbiol. 2011 Jun;19(6):257-62. doi: 10.1016/j.tim.2011.03.002. Epub 2011 Mar 31.

PMID:
21458997
20.

Cytoskeletal cross-talk in the control of T cell antigen receptor signaling.

Lasserre R, Alcover A.

FEBS Lett. 2010 Dec 15;584(24):4845-50. doi: 10.1016/j.febslet.2010.09.001. Epub 2010 Sep 7. Review.

21.

[Viral extracellular biofilms: a novel spreading trick of viruses?].

Thoulouze MI, Alcover A.

Med Sci (Paris). 2010 Jun-Jul;26(6-7):571-3. doi: 10.1051/medsci/2010266-7571. French. No abstract available.

22.

Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse.

Lasserre R, Charrin S, Cuche C, Danckaert A, Thoulouze MI, de Chaumont F, Duong T, Perrault N, Varin-Blank N, Olivo-Marin JC, Etienne-Manneville S, Arpin M, Di Bartolo V, Alcover A.

EMBO J. 2010 Jul 21;29(14):2301-14. doi: 10.1038/emboj.2010.127. Epub 2010 Jun 15.

23.

Biofilm-like extracellular viral assemblies mediate HTLV-1 cell-to-cell transmission at virological synapses.

Pais-Correia AM, Sachse M, Guadagnini S, Robbiati V, Lasserre R, Gessain A, Gout O, Alcover A, Thoulouze MI.

Nat Med. 2010 Jan;16(1):83-9. doi: 10.1038/nm.2065. Epub 2009 Dec 20.

PMID:
20023636
24.

Vesicle traffic to the immunological synapse: a multifunctional process targeted by lymphotropic viruses.

Alcover A, Thoulouze MI.

Curr Top Microbiol Immunol. 2010;340:191-207. doi: 10.1007/978-3-642-03858-7_10. Review.

PMID:
19960315
25.

Coronin-1A links cytoskeleton dynamics to TCR alpha beta-induced cell signaling.

Mugnier B, Nal B, Verthuy C, Boyer C, Lam D, Chasson L, Nieoullon V, Chazal G, Guo XJ, He HT, Rueff-Juy D, Alcover A, Ferrier P.

PLoS One. 2008;3(10):e3467. doi: 10.1371/journal.pone.0003467. Epub 2008 Oct 21.

26.

Modulation of the immunological synapse: a key to HIV-1 pathogenesis?

Fackler OT, Alcover A, Schwartz O.

Nat Rev Immunol. 2007 Apr;7(4):310-7. Review.

PMID:
17380160
27.

ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation.

Sol-Foulon N, Sourisseau M, Porrot F, Thoulouze MI, Trouillet C, Nobile C, Blanchet F, di Bartolo V, Noraz N, Taylor N, Alcover A, Hivroz C, Schwartz O.

EMBO J. 2007 Jan 24;26(2):516-26. Epub 2007 Jan 11.

28.

Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse.

Thoulouze MI, Sol-Foulon N, Blanchet F, Dautry-Varsat A, Schwartz O, Alcover A.

Immunity. 2006 May;24(5):547-61.

30.

ARF6 GTPase controls bacterial invasion by actin remodelling.

Balañá ME, Niedergang F, Subtil A, Alcover A, Chavrier P, Dautry-Varsat A.

J Cell Sci. 2005 May 15;118(Pt 10):2201-10. Epub 2005 Apr 19.

31.

[Activation-induced polarized recycling targets T cell receptors to the immunological synapse].

Alcover A, Thoulouze MI, Galli T.

Med Sci (Paris). 2005 Jan;21(1):9-10. French. No abstract available.

32.

Engaged and bystander T cell receptors are down-modulated by different endocytotic pathways.

Monjas A, Alcover A, Alarcón B.

J Biol Chem. 2004 Dec 31;279(53):55376-84. Epub 2004 Oct 28.

33.

Jamip1 (marlin-1) defines a family of proteins interacting with janus kinases and microtubules.

Steindler C, Li Z, Algarté M, Alcover A, Libri V, Ragimbeau J, Pellegrini S.

J Biol Chem. 2004 Oct 8;279(41):43168-77. Epub 2004 Jul 23.

34.

Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment.

Coumailleau F, Das V, Alcover A, Raposo G, Vandormael-Pournin S, Le Bras S, Baldacci P, Dautry-Varsat A, Babinet C, Cohen-Tannoudji M.

Mol Biol Cell. 2004 Oct;15(10):4444-56. Epub 2004 Jun 30.

35.

Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse; involvement of SNARE complexes.

Das V, Nal B, Dujeancourt A, Thoulouze MI, Galli T, Roux P, Dautry-Varsat A, Alcover A.

Immunity. 2004 May;20(5):577-88.

36.

Coronin-1 expression in T lymphocytes: insights into protein function during T cell development and activation.

Nal B, Carroll P, Mohr E, Verthuy C, Da Silva MI, Gayet O, Guo XJ, He HT, Alcover A, Ferrier P.

Int Immunol. 2004 Feb;16(2):231-40.

PMID:
14734608
37.

Characterization of a gene encoding two isoforms of a mitochondrial protein up-regulated by cyclosporin A in activated T cells.

Mascarell L, Auger R, Alcover A, Ojcius DM, Jungas T, Cadet-Daniel V, Kanellopoulos JM, Truffa-Bachi P.

J Biol Chem. 2004 Mar 12;279(11):10556-63. Epub 2003 Dec 18.

38.

Vav proteins, masters of the world of cytoskeleton organization.

Hornstein I, Alcover A, Katzav S.

Cell Signal. 2004 Jan;16(1):1-11. Review.

PMID:
14607270
39.

TCR dynamics in human mature T lymphocytes lacking CD3 gamma.

Torres PS, Alcover A, Zapata DA, Arnaud J, Pacheco A, Martín-Fernández JM, Villasevil EM, Sanal O, Regueiro JR.

J Immunol. 2003 Jun 15;170(12):5947-55.

40.

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

Ragimbeau J, Dondi E, Alcover A, Eid P, Uzé G, Pellegrini S.

EMBO J. 2003 Feb 3;22(3):537-47.

41.

Induction of the NF-kappaB cascade by recruitment of the scaffold molecule NEMO to the T cell receptor.

Weil R, Schwamborn K, Alcover A, Bessia C, Di Bartolo V, Israël A.

Immunity. 2003 Jan;18(1):13-26.

42.

T-lymphocyte activation induced by staphylococcal enterotoxin superantigens. Analysis of protein tyrosine phosphorylation.

Roumier A, Niedergang F, Alcover A.

Methods Mol Biol. 2003;214:127-35. No abstract available.

PMID:
12489459
43.

Membrane-cytoskeleton interactions during the formation of the immunological synapse and subsequent T-cell activation.

Das V, Nal B, Roumier A, Meas-Yedid V, Zimmer C, Olivo-Marin JC, Roux P, Ferrier P, Dautry-Varsat A, Alcover A.

Immunol Rev. 2002 Nov;189:123-35. Review.

PMID:
12445270
44.

Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways.

Groysman M, Hornstein I, Alcover A, Katzav S.

J Biol Chem. 2002 Dec 20;277(51):50121-30. Epub 2002 Oct 16.

45.

Defective assembly of the B-cell receptor chains accounts for its low expression in B-chronic lymphocytic leukaemia.

Payelle-Brogard B, Magnac C, Alcover A, Roux P, Dighiero G.

Br J Haematol. 2002 Sep;118(4):976-85.

PMID:
12199775
46.

Role of ICAM-3 in the initial interaction of T lymphocytes and APCs.

Montoya MC, Sancho D, Bonello G, Collette Y, Langlet C, He HT, Aparicio P, Alcover A, Olive D, Sánchez-Madrid F.

Nat Immunol. 2002 Feb;3(2):159-68. Epub 2002 Jan 7.

PMID:
11812993
47.

The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation.

Roumier A, Olivo-Marin JC, Arpin M, Michel F, Martin M, Mangeat P, Acuto O, Dautry-Varsat A, Alcover A.

Immunity. 2001 Nov;15(5):715-28.

48.

Internalization and intracellular fate of TCR-CD3 complexes.

Alcover A, Alarcón B.

Crit Rev Immunol. 2000;20(4):325-46. Review.

PMID:
11100805
49.

Rho regulates T cell receptor ITAM-induced lymphocyte spreading in an integrin-independent manner.

Borroto A, Gil D, Delgado P, Vicente-Manzanares M, Alcover A, Sánchez-Madrid F, Alarcón B.

Eur J Immunol. 2000 Dec;30(12):3403-10.

50.

CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation.

Michel F, Mangino G, Attal-Bonnefoy G, Tuosto L, Alcover A, Roumier A, Olive D, Acuto O.

J Immunol. 2000 Oct 1;165(7):3820-9.

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