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Items: 1 to 50 of 125

1.

Loss of adult 5-HT1A autoreceptors results in a paradoxical anxiogenic response to antidepressant treatment.

Turcotte-Cardin V, Vahid-Ansari F, Luckhart C, Daigle M, Geddes SD, Tanaka KF, Hen R, James J, Merali Z, Béïque JC, Albert PR.

J Neurosci. 2018 Dec 14. pii: 0352-18. doi: 10.1523/JNEUROSCI.0352-18.2018. [Epub ahead of print]

PMID:
30552180
2.

A Novel Alternative Splicing Mechanism That Enhances Human 5-HT1A Receptor RNA Stability Is Altered in Major Depression.

Le François B, Zhang L, Mahajan GJ, Stockmeier CA, Friedman E, Albert PR.

J Neurosci. 2018 Sep 19;38(38):8200-8210. doi: 10.1523/JNEUROSCI.0902-18.2018. Epub 2018 Aug 7.

PMID:
30093565
3.

Loss of MeCP2 in adult 5-HT neurons induces 5-HT1A autoreceptors, with opposite sex-dependent anxiety and depression phenotypes.

Philippe TJ, Vahid-Ansari F, Donaldson ZR, Le François B, Zahrai A, Turcotte-Cardin V, Daigle M, James J, Hen R, Merali Z, Albert PR.

Sci Rep. 2018 Apr 10;8(1):5788. doi: 10.1038/s41598-018-24167-8.

4.

Is poststroke depression the same as major depression?

Albert PR.

J Psychiatry Neurosci. 2018 Mar;43(2):76-78. No abstract available.

5.

Chronic Fluoxetine Induces Activity Changes in Recovery From Poststroke Anxiety, Depression, and Cognitive Impairment.

Vahid-Ansari F, Albert PR.

Neurotherapeutics. 2018 Jan;15(1):200-215. doi: 10.1007/s13311-017-0590-3.

6.

Abrogated Freud-1/Cc2d1a Repression of 5-HT1A Autoreceptors Induces Fluoxetine-Resistant Anxiety/Depression-Like Behavior.

Vahid-Ansari F, Daigle M, Manzini MC, Tanaka KF, Hen R, Geddes SD, Béïque JC, James J, Merali Z, Albert PR.

J Neurosci. 2017 Dec 6;37(49):11967-11978. doi: 10.1523/JNEUROSCI.1668-17.2017. Epub 2017 Nov 3.

7.

Length of axons expressing the serotonin transporter in orbitofrontal cortex is lower with age in depression.

Rajkowska G, Mahajan G, Legutko B, Challagundla L, Griswold M, Albert PR, Daigle M, Miguel-Hidalgo JJ, Austin MC, Blakely RD, Steffens DC, Stockmeier CA.

Neuroscience. 2017 Sep 17;359:30-39. doi: 10.1016/j.neuroscience.2017.07.006. Epub 2017 Jul 13.

8.

The adaptive brain in mental health: overcoming inherited risk factors.

Albert PR.

J Psychiatry Neurosci. 2017 Jan;42(1):3-5. No abstract available.

9.

Recruitment by the Repressor Freud-1 of Histone Deacetylase-Brg1 Chromatin Remodeling Complexes to Strengthen HTR1A Gene Repression.

Souslova T, Mirédin K, Millar AM, Albert PR.

Mol Neurobiol. 2017 Dec;54(10):8263-8277. doi: 10.1007/s12035-016-0306-4. Epub 2016 Dec 2.

10.

Sex-dependent adaptive changes in serotonin-1A autoreceptor function and anxiety in Deaf1-deficient mice.

Luckhart C, Philippe TJ, Le François B, Vahid-Ansari F, Geddes SD, Béïque JC, Lagace DC, Daigle M, Albert PR.

Mol Brain. 2016 Aug 3;9(1):77. doi: 10.1186/s13041-016-0254-y.

11.

Persistent post-stroke depression in mice following unilateral medial prefrontal cortical stroke.

Vahid-Ansari F, Lagace DC, Albert PR.

Transl Psychiatry. 2016 Aug 2;6(8):e863. doi: 10.1038/tp.2016.124.

12.

The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription.

Donaldson ZR, le Francois B, Santos TL, Almli LM, Boldrini M, Champagne FA, Arango V, Mann JJ, Stockmeier CA, Galfalvy H, Albert PR, Ressler KJ, Hen R.

Transl Psychiatry. 2016 Mar 1;6:e746. doi: 10.1038/tp.2015.226.

13.

Concentration-Dependent Dual Mode of Zn Action at Serotonin 5-HT1A Receptors: In Vitro and In Vivo Studies.

Satała G, Duszyńska B, Stachowicz K, Rafalo A, Pochwat B, Luckhart C, Albert PR, Daigle M, Tanaka KF, Hen R, Lenda T, Nowak G, Bojarski AJ, Szewczyk B.

Mol Neurobiol. 2016 Dec;53(10):6869-6881. Epub 2015 Dec 12.

14.

Chronic mild stress and antidepressant treatment alter 5-HT1A receptor expression by modifying DNA methylation of a conserved Sp4 site.

Le François B, Soo J, Millar AM, Daigle M, Le Guisquet AM, Leman S, Minier F, Belzung C, Albert PR.

Neurobiol Dis. 2015 Oct;82:332-341. doi: 10.1016/j.nbd.2015.07.002. Epub 2015 Jul 15.

15.

Why is depression more prevalent in women?

Albert PR.

J Psychiatry Neurosci. 2015 Jul;40(4):219-21. No abstract available.

16.

COMT polymorphism modulates the resting-state EEG alpha oscillatory response to acute nicotine in male non-smokers.

Bowers H, Smith D, de la Salle S, Choueiry J, Impey D, Philippe T, Dort H, Millar A, Daigle M, Albert PR, Beaudoin A, Knott V.

Genes Brain Behav. 2015 Jul;14(6):466-76. doi: 10.1111/gbb.12226. Epub 2015 Jul 15.

17.

Evidence revealing deregulation of the KLF11-MAO A pathway in association with chronic stress and depressive disorders.

Harris S, Johnson S, Duncan JW, Udemgba C, Meyer JH, Albert PR, Lomberk G, Urrutia R, Ou XM, Stockmeier CA, Wang JM.

Neuropsychopharmacology. 2015 May;40(6):1373-82. doi: 10.1038/npp.2014.321. Epub 2014 Dec 15.

18.

Editorial. Thematic section: serotonin and its receptors.

Albert PR.

Int J Neuropsychopharmacol. 2014 Nov;17(11):1727-8. doi: 10.1017/S1461145714001096. No abstract available.

19.

Stress-induced alterations in 5-HT1A receptor transcriptional modulators NUDR and Freud-1.

Szewczyk B, Kotarska K, Daigle M, Misztak P, Sowa-Kucma M, Rafalo A, Curzytek K, Kubera M, Basta-Kaim A, Nowak G, Albert PR.

Int J Neuropsychopharmacol. 2014 Nov;17(11):1763-75. doi: 10.1017/S146114571400100X. Epub 2014 Jun 19.

20.

Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression.

Albert PR, Vahid-Ansari F, Luckhart C.

Front Behav Neurosci. 2014 Jun 6;8:199. doi: 10.3389/fnbeh.2014.00199. eCollection 2014. Review.

21.

Light up your life: optogenetics for depression?

Albert PR.

J Psychiatry Neurosci. 2014 Jan;39(1):3-5. doi: 10.1503/jpn.130267. No abstract available.

23.

The expression of KLF11 (TIEG2), a monoamine oxidase B transcriptional activator in the prefrontal cortex of human alcohol dependence.

Udemgba C, Johnson S, Stockmeier CA, Luo J, Albert PR, Wang J, May WL, Rajkowska G, Harris S, Sittman DB, Ou XM.

Alcohol Clin Exp Res. 2014 Jan;38(1):144-51. doi: 10.1111/acer.12229. Epub 2013 Aug 5.

24.

DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA.

Ordureau A, Enesa K, Nanda S, Le Francois B, Peggie M, Prescott A, Albert PR, Cohen P.

J Biol Chem. 2013 Aug 23;288(34):24569-80. doi: 10.1074/jbc.M113.479550. Epub 2013 Jul 11.

25.

Role of protein kinase C in agonist-induced desensitization of 5-HT₁A receptor coupling to calcium channels in F11 cells.

Wu X, Kushwaha N, Banerjee P, Albert PR, Penington NJ.

Eur J Pharmacol. 2013 Apr 15;706(1-3):84-91. doi: 10.1016/j.ejphar.2013.03.005. Epub 2013 Mar 16.

26.

The neurobiology of depression--revisiting the serotonin hypothesis. II. Genetic, epigenetic and clinical studies.

Albert PR, Benkelfat C.

Philos Trans R Soc Lond B Biol Sci. 2013 Feb 25;368(1615):20120535. doi: 10.1098/rstb.2012.0535. Print 2013.

27.

Drugs for kids: good or bad?

Albert PR.

J Psychiatry Neurosci. 2012 Sep;37(5):293-5. doi: 10.1503/jpn.120140. No abstract available.

28.

Transcriptional regulation of the 5-HT1A receptor: implications for mental illness.

Albert PR.

Philos Trans R Soc Lond B Biol Sci. 2012 Sep 5;367(1601):2402-15. doi: 10.1098/rstb.2011.0376. Review.

29.

The neurobiology of depression--revisiting the serotonin hypothesis. I. Cellular and molecular mechanisms.

Albert PR, Benkelfat C, Descarries L.

Philos Trans R Soc Lond B Biol Sci. 2012 Sep 5;367(1601):2378-81. doi: 10.1098/rstb.2012.0190.

30.

Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein pathway in stress-induced monoamine oxidase A expression.

Grunewald M, Johnson S, Lu D, Wang Z, Lomberk G, Albert PR, Stockmeier CA, Meyer JH, Urrutia R, Miczek KA, Austin MC, Wang J, Paul IA, Woolverton WL, Seo S, Sittman DB, Ou XM.

J Biol Chem. 2012 Jul 13;287(29):24195-206. doi: 10.1074/jbc.M112.373936. Epub 2012 May 24.

31.

17β-estradiol-induced regulation of the novel 5-HT1A-related transcription factors NUDR and Freud-1 in SH SY5Y cells.

Adeosun SO, Albert PR, Austin MC, Iyo AH.

Cell Mol Neurobiol. 2012 May;32(4):517-21. doi: 10.1007/s10571-012-9809-3. Epub 2012 Feb 11.

32.

Increased serotonin-1A (5-HT1A) autoreceptor expression and reduced raphe serotonin levels in deformed epidermal autoregulatory factor-1 (Deaf-1) gene knock-out mice.

Czesak M, Le François B, Millar AM, Deria M, Daigle M, Visvader JE, Anisman H, Albert PR.

J Biol Chem. 2012 Feb 24;287(9):6615-27. doi: 10.1074/jbc.M111.293027. Epub 2012 Jan 9.

33.

Ser/ Thr residues at α3/β5 loop of Gαs are important in morphine-induced adenylyl cyclase sensitization but not mitogen-activated protein kinase phosphorylation.

Seyedabadi M, Ostad SN, Albert PR, Dehpour AR, Rahimian R, Ghazi-Khansari M, Ghahremani MH.

FEBS J. 2012 Feb;279(4):650-60. doi: 10.1111/j.1742-4658.2011.08459.x. Epub 2012 Jan 13.

34.

What is a functional genetic polymorphism? Defining classes of functionality.

Albert PR.

J Psychiatry Neurosci. 2011 Nov;36(6):363-5. doi: 10.1503/jpn.110137. No abstract available.

35.

The reduction of R1, a novel repressor protein for monoamine oxidase A, in major depressive disorder.

Johnson S, Stockmeier CA, Meyer JH, Austin MC, Albert PR, Wang J, May WL, Rajkowska G, Overholser JC, Jurjus G, Dieter L, Johnson C, Sittman DB, Ou XM.

Neuropsychopharmacology. 2011 Sep;36(10):2139-48. doi: 10.1038/npp.2011.105. Epub 2011 Jun 8.

36.

Transcriptional dysregulation of 5-HT1A autoreceptors in mental illness.

Albert PR, Le François B, Millar AM.

Mol Brain. 2011 May 27;4:21. doi: 10.1186/1756-6606-4-21. Review.

37.

Brain derived neurotrophic factor, cardiopulmonary fitness and cognition in patients with coronary artery disease.

Swardfager W, Herrmann N, Marzolini S, Saleem M, Shammi P, Oh PI, Albert PR, Daigle M, Kiss A, Lanctôt KL.

Brain Behav Immun. 2011 Aug;25(6):1264-71. doi: 10.1016/j.bbi.2011.04.017. Epub 2011 Apr 30.

38.

Neurotensin triggers dopamine D2 receptor desensitization through a protein kinase C and beta-arrestin1-dependent mechanism.

Thibault D, Albert PR, Pineyro G, Trudeau LÉ.

J Biol Chem. 2011 Mar 18;286(11):9174-84. doi: 10.1074/jbc.M110.166454. Epub 2011 Jan 13.

39.

Identification of Novel Transcriptional Regulators in the Nervous System.

Remes-Lenicov F, Jacobsen KX, Rogaeva A, Czesak M, Hadjighasem M, Daigle M, Albert PR.

In: Chattopadhyay A, editor. Serotonin Receptors in Neurobiology. Boca Raton (FL): CRC Press/Taylor & Francis; 2007. Chapter 5.

40.

Region-specific regulation of 5-HT1A receptor expression by Pet-1-dependent mechanisms in vivo.

Jacobsen KX, Czesak M, Deria M, Le François B, Albert PR.

J Neurochem. 2011 Mar;116(6):1066-76. doi: 10.1111/j.1471-4159.2010.07161.x. Epub 2011 Jan 24.

41.

Freud-2/CC2D1B mediates dual repression of the serotonin-1A receptor gene.

Hadjighassem MR, Galaraga K, Albert PR.

Eur J Neurosci. 2011 Jan;33(2):214-23. doi: 10.1111/j.1460-9568.2010.07498.x. Epub 2010 Dec 14.

42.

Epigenetics in mental illness: hope or hype?

Albert PR.

J Psychiatry Neurosci. 2010 Nov;35(6):366-8. doi: 10.1503/jpn.100148. No abstract available.

43.

A functional alternative splicing mutation in human tryptophan hydroxylase-2.

Zhang X, Nicholls PJ, Laje G, Sotnikova TD, Gainetdinov RR, Albert PR, Rajkowska G, Stockmeier CA, Speer MC, Steffens DC, Austin MC, McMahon FJ, Krishnan KR, Garcia-Blanco MA, Caron MG.

Mol Psychiatry. 2011 Dec;16(12):1169-76. doi: 10.1038/mp.2010.99. Epub 2010 Sep 21.

44.

Modifying 5-HT1A Receptor Gene Expression as a New Target for Antidepressant Therapy.

Albert PR, François BL.

Front Neurosci. 2010 Jun 17;4:35. doi: 10.3389/fnins.2010.00035. eCollection 2010.

45.

TNFAIP8: a new effector for Galpha(i) coupling to reduce cell death and induce cell transformation.

Laliberté B, Wilson AM, Nafisi H, Mao H, Zhou YY, Daigle M, Albert PR.

J Cell Physiol. 2010 Nov;225(3):865-74. doi: 10.1002/jcp.22297.

46.

Decreased expression of Freud-1/CC2D1A, a transcriptional repressor of the 5-HT1A receptor, in the prefrontal cortex of subjects with major depression.

Szewczyk B, Albert PR, Rogaeva A, Fitzgibbon H, May WL, Rajkowska G, Miguel-Hidalgo JJ, Stockmeier CA, Woolverton WL, Kyle PB, Wang Z, Austin MC.

Int J Neuropsychopharmacol. 2010 Sep;13(8):1089-101. doi: 10.1017/S1461145710000301. Epub 2010 Apr 15.

47.

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes.

Yip L, Su L, Sheng D, Chang P, Atkinson M, Czesak M, Albert PR, Collier AR, Turley SJ, Fathman CG, Creusot RJ.

Nat Immunol. 2009 Sep;10(9):1026-33. doi: 10.1038/ni.1773. Epub 2009 Aug 9.

48.

Differential regulation of the serotonin 1 A transcriptional modulators five prime repressor element under dual repression-1 and nuclear-deformed epidermal autoregulatory factor by chronic stress.

Iyo AH, Kieran N, Chandran A, Albert PR, Wicks I, Bissette G, Austin MC.

Neuroscience. 2009 Nov 10;163(4):1119-27. doi: 10.1016/j.neuroscience.2009.07.053. Epub 2009 Jul 30.

49.

Human Freud-2/CC2D1B: a novel repressor of postsynaptic serotonin-1A receptor expression.

Hadjighassem MR, Austin MC, Szewczyk B, Daigle M, Stockmeier CA, Albert PR.

Biol Psychiatry. 2009 Aug 1;66(3):214-22. doi: 10.1016/j.biopsych.2009.02.033. Epub 2009 May 7.

50.

GAP1(IP4BP)/RASA3 mediates Galphai-induced inhibition of mitogen-activated protein kinase.

Nafisi H, Banihashemi B, Daigle M, Albert PR.

J Biol Chem. 2008 Dec 19;283(51):35908-17. doi: 10.1074/jbc.M803622200. Epub 2008 Oct 24.

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